Homocysteine and major coronary events: a prospective population study amongst women.

abstract：:Vasopressin (AVP) plays a major role in the regulation of water and sodium homeostasis by its antidiuretic action on the kidney, mediated by V2 receptors. AVP secretion is stimulated by a rise in plasma osmolality, a decline in blood volume or stress. V1a receptors are expressed in vascular smooth muscle cells, but th...

journal_title：Journal of internal medicine

authors： Bankir L,Bichet DG,Morgenthaler NG

更新日期：2017-10-01 00:00:00

abstract：:The systemic regulation of immune reactions by the nervous system is well studied and depends on the release of hormones. Some regional regulations of immune reactions, on the other hand, depend on specific neural pathways. Better understanding of these regulations will expand therapeutic applications for neuroimmune ...

journal_title：Journal of internal medicine

authors： Kamimura D,Murakami M

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Haemostatic imbalance may be an aetiological factor in the development of acute coronary syndromes. Inherited resistance to activated protein C (APC) is a common disorder associated with hypercoagulability and lifelong risk of venous thrombosis. APC resistance is due to a single mutation in the gene coding fo...

journal_title：Journal of internal medicine

authors： Holm J,Zöller B,Berntorp E,Erhardt L,Dahlbäck B

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthesis causing endothelial dysfunction, an early sign of atherogenesis. Symmetric dimethylarginine (SDMA) does not inhibit NO synthases. Peripheral arterial disease (PAD) is a systemic indication of atherosclerosis. METHOD...

journal_title：Journal of internal medicine

authors： Böger RH,Endres HG,Schwedhelm E,Darius H,Atzler D,Lüneburg N,von Stritzky B,Maas R,Thiem U,Benndorf RA,Diehm C

更新日期：2011-03-01 00:00:00

abstract：:The B lymphocyte-associated antigen CD20 is becoming an important immunotherapy target for autoimmune diseases, although its biological function has not been defined. Besides rheumatoid arthritis, growing experience with B cell-depleting therapy indicates that it may be effective in Sjögren's syndrome, dermatomyositis...

journal_title：Journal of internal medicine

authors： Perosa F,Prete M,Racanelli V,Dammacco F

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:Peroxidation of lipoproteins may be of critical importance in the development of atherosclerosis. Tocopherol is considered to be the most effective lipid-soluble antioxidant. The main aim of this study was to measure the serum tocopherol concentrations in a Swedish reference population and to relate them to ...

journal_title：Journal of internal medicine

authors： Ohrvall M,Tengblad S,Vessby B

更新日期：1993-07-01 00:00:00

abstract：:Pheochromocytoma endures as a life-threatening disorder. In the absence of systemic hypertension, diagnosis may be difficult. We present a 46-year-old normotensive male with a history of presyncope. One of these episodes could be documented, and revealed symptomatic bradycardia suspicious of sinus node arrest. Due to ...

journal_title：Journal of internal medicine

authors： Zweiker R,Tiemann M,Eber B,Schumacher M,Fruhwald FM,Lipp R,Lax S,Pristautz H,Klein W

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVES:The effects of atorvastatin, a new synthetic HMG-CoA reductase inhibitor, were investigated in patients with familial hypercholesterolaemia (FH), with high LDLc levels whilst on standard treatment. DESIGN:Open treatment with 40 mg atorvastatin daily for 6 weeks, followed by another 6 weeks with 80 mg atorva...

journal_title：Journal of internal medicine

authors： Hoogerbrugge N

更新日期：1998-08-01 00:00:00

abstract：:Cancer is a genetic disease caused by 'gain of function' mutations of oncogenes and 'loss of function' mutations of tumour suppressors and of genes involved in DNA repair mechanisms. The RET gene encodes a tyrosine kinase receptor for molecules belonging to the glial cell line-derived neurotrophic factor (GDNF) family...

journal_title：Journal of internal medicine

authors： Santoro M,Melillo RM,Carlomagno F,Visconti R,De Vita G,Salvatore G,Lupoli G,Fusco A,Vecchio G

更新日期：1998-06-01 00:00:00

abstract：:A 59-year-old male patient presented with invalidating osteomalacia of 2.5 years' duration. The osteomalacia was caused by severe malabsorption due to gluten-sensitive enteropathy (GSE). There were no other signs or symptoms of GSE in this patient. Clinical presentation with monosymptomatic osteomalacia is very unusua...

journal_title：Journal of internal medicine

authors： De Boer WA,Tytgat GN

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the prognostic value of exercise testing performed soon after acute myocardial infarction (AMI) in patients treated with thrombolytic therapy. DESIGN:A 1-year prospective follow-up of 185 subjects treated with thrombolytic therapy who survived AMI, and who performed exercise testing 3 weeks afte...

journal_title：Journal of internal medicine

authors： Abboud L,Hir J,Eisen I,Markiewicz W

更新日期：1994-11-01 00:00:00

abstract：:A survey among Danish students revealed that 33 (7.2%) of the respondents had experience with hallucinogenic mushrooms (HM). Afterwards these students answered an extended questionnaire about habits and pattern of consumption. It seems that mushroom use is experimental and may be due to risk-seeking behaviour but is m...

journal_title：Journal of internal medicine

authors： Lassen JF,Lassen NF,Skov J

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Gallium-67 (67Ga) scintigraphy may be useful in evaluating patients with retroperitoneal fibrosis (RPF), but a systematic assessment of its value is lacking. OBJECTIVE:Prospective evaluation of the value of 67Ga scintigraphy in assessing active RPF disease and in predicting treatment response. METHODS:Thir...

journal_title：Journal of internal medicine

authors： van Bommel EF,Siemes C,van der Veer SJ,Han SH,Huiskes AW,Hendriksz TR

更新日期：2007-08-01 00:00:00

abstract：:An inverse relationship between the concentration of high-density lipoprotein (HDL) cholesterol and the risk of developing cardiovascular is well established. There are several documented functions of HDLs that may contribute to a protective role of these lipoproteins. These include the ability of HDLs to promote the ...

journal_title：Journal of internal medicine

authors： Barter PJ,Rye KA

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:It has been hypothesized that epicardial adipose tissue (EAT) exerts pathogenic effects on cardiac structures. We analysed the associations between EAT and both cardiovascular (CV) disease risk factors and CV events in patients with chronic kidney disease (CKD). PATIENTS AND METHODS:We included 277 nondialy...

journal_title：Journal of internal medicine

authors： Cordeiro AC,Amparo FC,Oliveira MA,Amodeo C,Smanio P,Pinto IM,Lindholm B,Stenvinkel P,Carrero JJ

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:The mortality from coronary heart disease (CHD) is exceptionally low in northernmost Finland, the Sámi (formerly known as Lapp) area. To clarify the reasons for this, the levels of serum cholesterol, other classic risk factors, and major antioxidants, alpha-tocopherol, retinol, albumin and selenium were dete...

journal_title：Journal of internal medicine

authors： Luoma PV,Näyhä S,Sikkilä K,Hassi J

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:Study patient characteristics, morbidity patterns and drug regimens associated with fatal adverse drug events (FADEs) amongst medical department inpatients. DESIGN:An observational, descriptive study using aggregated medical records, autopsies and pre and postmortem drug analyses. SETTING:A department of in...

journal_title：Journal of internal medicine

authors： Buajordet I,Ebbesen J,Erikssen J,Brørs O,Hilberg T

更新日期：2001-10-01 00:00:00

abstract：:Poikilothermia syndrome is a rare cause of intrinsic thermoregulatory failure. Patients with this syndrome regulate body temperature poorly, if at all. Recently, a patient was referred to us who had clinical evidence of poikilothermia syndrome, as well as long-standing multiple sclerosis. Computerized tomography and m...

journal_title：Journal of internal medicine

authors： Kurz A,Sessler DI,Tayefeh F,Goldberger R

更新日期：1998-11-01 00:00:00

abstract：:When and where did modern humans evolve? How did our ancestors spread over the world? Traditionally, answers to questions such as these have been sought in historical, archaeological, and fossil records. However, increasingly genetic data provide information about the evolution of our species. In this review, we focus...

journal_title：Journal of internal medicine

authors： Kaessmann H,Pääbo S

更新日期：2002-01-01 00:00:00

abstract：:This review discusses the interplay between multimorbidity (i.e. co-occurrence of more than one chronic health condition in an individual) and functional impairment (i.e. limitations in mobility, strength or cognition that may eventually hamper a person's ability to perform everyday tasks). On the one hand, diseases b...

journal_title：Journal of internal medicine

authors： Calderón-Larrañaga A,Vetrano DL,Ferrucci L,Mercer SW,Marengoni A,Onder G,Eriksdotter M,Fratiglioni L

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:To investigate the concordance of anti-hepatitis C virus (anti-HCV) reactivity by a second-generation enzyme immunoassay (EIA-2) and by a four-antigen recombinant immunoblot assay (4-RIBA) in homosexual men, in comparison with that found in other sexually active groups and blood donors. DESIGN:Prospective s...

journal_title：Journal of internal medicine

authors： Andreu J,Abad MA,Sanchez-Quijano A,Torronteras R,Luque F,Garcia de las Heras J,Soto B,Pineda JA,Leal M,Lissen E

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVES:Autoantibodies to apolipoprotein (apo) B-100 peptides are present in human plasma and have been shown to be associated with decreased cardiovascular risk. The present study aimed to determine if apo B-100 peptide vaccines are atheroprotective in mice expressing human apo B-100 and if the effectiveness of the...

journal_title：Journal of internal medicine

authors： Fredrikson GN,Björkbacka H,Söderberg I,Ljungcrantz I,Nilsson J

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Intravenous nitrate therapy has been shown to improve short-term outcome of acute heart failure patients treated in the intensive care unit. The potential of a noninvasive high-dose nitrate strategy in the Emergency Department and the general ward remains unknown. METHODS:A total of 128 consecutive acute he...

journal_title：Journal of internal medicine

authors： Breidthardt T,Noveanu M,Potocki M,Reichlin T,Egli P,Hartwiger S,Socrates T,Gayat E,Christ M,Mebazaa A,Mueller C

更新日期：2010-03-01 00:00:00

abstract：:A normal brain function requires constant levels of cholesterol, and the need for constancy seems to be higher here than in any other organ. Nature has met this need by isolation of brain cholesterol by a highly efficient blood-brain barrier. As a low synthesis of cholesterol is present in the brain, a mechanism for c...

journal_title：Journal of internal medicine

authors： Björkhem I

更新日期：2006-12-01 00:00:00

abstract：:The fruitless search for the cause of Crohn's disease has been conducted for more than a century. Various theories, including autoimmunity, mycobacterial infection and aberrant response to food and other ingested materials, have been abandoned for lack of robust proof. This review will provide the evidence, obtained f...

journal_title：Journal of internal medicine

authors： Segal AW

更新日期：2019-10-01 00:00:00

abstract：:In Sweden, prophylactic treatment of boys with severe haemophilia has been practised since 1958 in an attempt to convert the disease from a severe to a milder form. The present study population consisted of 60 severe haemophiliacs (52 A, 8 B), aged 3-32 years. Treatment is started when the boys are 1-2 years of age, t...

journal_title：Journal of internal medicine

authors： Nilsson IM,Berntorp E,Löfqvist T,Pettersson H

更新日期：1992-07-01 00:00:00

abstract：:A patient with undiagnosed, long-standing coeliac disease had multiple hot spots on skeletal scintigraphy, similar to those observed in malignant disease metastatic to the skeleton. A gluten-free diet corrected the pathological laboratory values, and a repeat skeletal scintigram 15 months after the first one was norma...

journal_title：Journal of internal medicine

authors： Paul R

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVES:A low level of education is associated with an increased risk of developing a dementia disorder, as well as with a higher risk of cardiovascular disease. The aim of this study was to investigate the association between education and cardiovascular risk factors, and to study the relation between these factors...

journal_title：Journal of internal medicine

authors： Kilander L,Nyman H,Boberg M,Lithell H

更新日期：1997-10-01 00:00:00

abstract：:Patients with established coronary disease and abnormalities of lipid metabolism represent a particularly important subgroup, since their mortality risk is typically 10 times greater than that amongst-subjects with comparable risk factors but no clinical history. Such patients are commonly treated initially with anti-...

journal_title：Journal of internal medicine

authors： Brown BG,Zhao XQ,Bardsley J,Albers JJ

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To investigate the adjusted relative risk of cardiovascular disease (CVD) events in offspring of parents with cardiovascular mortality before 75 years. SETTING:The city of Malmö, Sweden. DESIGN:A follow-up study based on register linkage analyses. SUBJECTS AND METHODS:In the Malmö Preventive Project (MPP),...

journal_title：Journal of internal medicine

authors： Nilsson PM,Nilsson JA,Berglund G

更新日期：2004-02-01 00:00:00