Effects of atorvastatin on serum lipids of patients with familial hypercholesterolaemia.

abstract：:Sepsis is a major clinical problem in intensive care. The mortality in septic shock is high, and predominantly due to cardiovascular collapse and multiple organ dysfunction. In sepsis high levels of circulating hyaluronan have been found, correlating to disease severity and prognosis. The reason behind the increased l...

journal_title：Journal of internal medicine

authors： Berg S

更新日期：1997-07-01 00:00:00

abstract：:We report two cases of fulminant hepatic failure in HIV-1-infected patients treated with didanosine (ddI). Clinical manifestations including vomiting, diarrhoea and dyspnoea were identical in both cases. Biological data mainly revealed hepatic failure and lactic acidosis. Histological examination of liver biopsies sho...

journal_title：Journal of internal medicine

authors： Bissuel F,Bruneel F,Habersetzer F,Chassard D,Cotte L,Chevallier M,Bernuau J,Lucet JC,Trepo C

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:To assess the impact of delay in emergency department (ED) on outcome of critically ill patients admitted to the medical intensive care unit (MICU). Outcome was defined as hospital mortality and as health-related quality of life (HRQoL) at 6 months after intensive care assessed by the 15D measure. The 15D is ...

journal_title：Journal of internal medicine

authors： Saukkonen KA,Varpula M,Räsänen P,Roine RP,Voipio-Pulkki LM,Pettilä V

更新日期：2006-12-01 00:00:00

abstract：:Multimorbidity, the simultaneous presence of multiple health conditions in an individual, is an increasingly common phenomenon globally. The systematic assessment of the quality of care delivered to people with multimorbidity will be key to informing the organization of services for meeting their complex needs. Yet, c...

journal_title：Journal of internal medicine

authors： Valderas JM,Gangannagaripalli J,Nolte E,Boyd CM,Roland M,Sarria-Santamera A,Jones E,Rijken M

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:Small LDL particle size has been shown to be associated with coronary artery disease. However, no previous study has been performed relating LDL particle size to ultrasound measurement of atherosclerosis in hypercholesterolaemic subjects. The main aims of the present study were therefore: (i) to investigate ...

journal_title：Journal of internal medicine

authors： Hulthe J,Wiklund O,Bondjers G,Wikstrand J

更新日期：2000-07-01 00:00:00

abstract：:Hyponatraemia (HN) can result from a wide range of mechanisms, and therapy must be individualized. Two theories of the origin of HN in acute brain disease have prevailed. The first is the cerebral salt wasting syndrome (CSWS), where excessive natriuresis caused by some unknown cerebral natriuretic factor lowers the to...

journal_title：Journal of internal medicine

authors： Kröll M,Juhler M,Lindholm J

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:Therapeutic paracentesis in patients with cirrhosis is associated with a circulatory dysfunction. Intravenous albumin has been used to prevent the circulatory dysfunction; however, the use of albumin is controversial and costly. Splanchnic vasodilation is mainly responsible for circulatory dysfunction in thes...

journal_title：Journal of internal medicine

authors： Singh V,Kumar B,Nain CK,Singh B,Sharma N,Bhalla A,Sharma AK

更新日期：2006-07-01 00:00:00

abstract：:The hypothesis that asymptomatic visual field defects can be found in patients with carotid transient ischaemic attacks (TIA) or minor strokes was tested. Twenty-two consecutive male patients with TIA and 18 patients with minor strokes from the carotid artery territory were examined by perimetry, cerebral computerised...

journal_title：Journal of internal medicine

authors： Falke P,Abela BM Jr,Krakau CE,Lilja B,Lindgärde F,Maly P,Stavenow L

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Bradykinin-mediated angioedema (AE) is a complication associated with thrombolysis for acute ischemic stroke. Risk factors are unknown and management is discussed. OBJECTIVES:To clarify risk factors associated with bradykinin-mediated AE after thrombolysis for acute ischemic stroke. METHODS:In a case-contr...

journal_title：Journal of internal medicine

authors： Vigneron C,Lécluse A,Ronzière T,Bouillet L,Boccon-Gibod I,Gayet S,Doche E,Smadja D,Di Legge S,Dumont F,Gaudron M,Ion I,Marcel S,Sévin M,Vlaicu MB,Launay D,Arnaud I,Girard-Madoux P,Héroum C,Lefèvre S,Marc G,Obadi

更新日期：2019-12-01 00:00:00

abstract：:Previous studies in patients with peripheral arterial disease (PAD) have shown that the prognosis is relatively good when the distal systolic ankle index (ankle systolic pressure/arm systolic pressure) is above 50% and the distal toe systolic pressure is above 40 mmHg. In 132 patients suspected of PAD in the legs we i...

journal_title：Journal of internal medicine

authors： Christensen JH,Freundlich M,Jacobsen BA,Falstie-Jensen N

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Pulse pressure (PP), a marker of cyclic strain on the arterial wall, is a significant predictor of cardiovascular (CV) risk, particularly regarding the incidence of coronary arterial stenosis. Genes related to haemostatic and/or fibrinolytic factors are consistently influenced in vitro by mechanical strain. ...

journal_title：Journal of internal medicine

authors： Mourad JJ,du Cailar G,Nazal EM,Safar ME,Mimran A

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:P2X7 receptor (P2X7R), trigger of acute inflammatory responses via the NLRP3 inflammasome, is hyperfunctioning in patients with Sjögren's syndrome (SS), where it stimulates IL-18 production. Some patients with SS develop a mucosa-associated lymphoid tissue non-Hodgkin's lymphoma (MALT-NHL). OBJECTIVES:To pr...

journal_title：Journal of internal medicine

authors： Baldini C,Santini E,Rossi C,Donati V,Solini A

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:The relationship between physical activity and cognitive function is intriguing but controversial. We performed a systematic meta-analysis of all the available prospective studies that investigated the association between physical activity and risk of cognitive decline in nondemented subjects. METHODS:We con...

journal_title：Journal of internal medicine

authors： Sofi F,Valecchi D,Bacci D,Abbate R,Gensini GF,Casini A,Macchi C

更新日期：2011-01-01 00:00:00

abstract：:A 40-year-old woman with previous parathyroidectomy for adenoma was found to have a serum calcium level of 5.35 mmol l-1 (21.4 mg dl-1). Inadvertent calcium overdose had occurred because of her mistaken belief that if some prescribed calcium was good, then more was better. Her misconception is in contrast with that of...

journal_title：Journal of internal medicine

authors： McAlister NH,Abrams HB,Schlosser R,Sturtridge W

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:Patients with psoriasis are prone to premature atherosclerosis and increased risk of cardiovascular disease events. However, the prevalence and extent of atherosclerosis in patients with psoriasis are unknown. DESIGN:A cross-sectional study. SETTING AND SUBJECTS:The prevalence and extent of coronary and car...

journal_title：Journal of internal medicine

authors： Yiu KH,Yeung CK,Zhao CT,Chan JC,Siu CW,Tam S,Wong CS,Yan GH,Yue WS,Khong PL,Chan HH,Tse HF

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:Few studies have simultaneously analysed the influence of elevated serum uric acid (UA) on acute myocardial infarction (AMI), ischaemic and haemorrhagic stroke (IS, HS) and congestive heart failure (CHF) in large healthy populations. We, here, examine UA as a risk factor for AMI, stroke and CHF by age and ge...

journal_title：Journal of internal medicine

authors： Holme I,Aastveit AH,Hammar N,Jungner I,Walldius G

更新日期：2009-12-01 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder that affects approximately 10% of the population. Diet triggers symptoms in the vast majority of individuals with IBS. In view of this, there has been a focus on the role of diet in IBS. The diets currently being headlined for IBS include ...

journal_title：Journal of internal medicine

authors： Rej A,Aziz I,Tornblom H,Sanders DS,Simrén M

更新日期：2019-11-01 00:00:00

abstract：:There is good evidence that both inherited and environmental factors influence the risk of developing asthma. Only recently, large well-designed studies have been undertaken with the power to identify the genetic causes for asthma, and methods developed in parallel with the Human Genome Project, such as gene expressio...

journal_title：Journal of internal medicine

authors： Melén E,Pershagen G

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Studies have shown that lipoprotein(a) [Lp(a)], an important carrier of oxidized phospholipids, is causally related to calcific aortic valve stenosis (CAVS). Recently, we found that Lp(a) mediates the development of CAVS through autotaxin (ATX). OBJECTIVE:To determine the predictive value of circulating ATX...

journal_title：Journal of internal medicine

authors： Nsaibia MJ,Mahmut A,Boulanger MC,Arsenault BJ,Bouchareb R,Simard S,Witztum JL,Clavel MA,Pibarot P,Bossé Y,Tsimikas S,Mathieu P

更新日期：2016-11-01 00:00:00

abstract：:Findings from preclinical and clinical studies show that vascular normalization represents a novel strategy to enhance the efficacy of and overcome the acquired resistance to anti-angiogenic therapies in cancer. Several mechanisms of tumour vessel normalization have been revealed. Amongst them, secreted class 3 semaph...

journal_title：Journal of internal medicine

authors： Serini G,Bussolino F,Maione F,Giraudo E

更新日期：2013-02-01 00:00:00

abstract：:The first unifying definition for the metabolic syndrome was proposed by WHO in 1998. In accordance to this, patients with type 2 diabetes mellitus or impaired glucose tolerance have the syndrome if they fulfil two of the criteria: hypertension, dyslipidaemia, obesity/abdominal obesity and microalbuminuria. Persons wi...

journal_title：Journal of internal medicine

authors： Groop L,Orho-Melander M

更新日期：2001-08-01 00:00:00

abstract：:Recent studies have demonstrated that replacement of C-peptide to normal physiological concentrations in insulin-dependent diabetic (IDDM) patients on a short-term basis (1-3 h) results in decreased glomerular hyperfiltration, augmented glucose utilization and improved autonomic nervous function. More prolonged admini...

journal_title：Journal of internal medicine

authors： Wahren J,Johansson BL,Wallberg-Henriksson H,Linde B,Fernqvist-Forbes E,Zierath JR

更新日期：1996-09-01 00:00:00

abstract：:Two cases of young healthy males presenting with cardiac tamponade and developing clinical adrenal insufficiency within a few weeks are described. On presentation they had a brisk inflammatory response with complement activation. Both had signs of subclinical hepatitis, and both have later shown evidence of thyroid in...

journal_title：Journal of internal medicine

authors： Torfoss D,von de Lippe E,Jacobsen D

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the predictive accuracy of the scoring system Rapid Acute Physiology score (RAPS) in nonsurgical patients attending the emergency department (ED) regarding in-hospital mortality and length of stay in hospital (LOS), and to investigate whether the predictive ability of RAPS could be improved by ex...

journal_title：Journal of internal medicine

authors： Olsson T,Terent A,Lind L

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To develop a method to evaluate routine management practices concerning lipid-lowering treatment in patients with ischaemic heart disease (IHD) in a large geographic area. DESIGN:A register-based study linking information on IHD with cholesterol levels and prescriptions on lipid-lowering medications by perso...

journal_title：Journal of internal medicine

authors： Kanstrup H,Lassen JF,Heickendorff L,Lauritzen T,Larsen ML

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:To assess the coexistence of hypertension and diabetes, associations with cardiovascular risk factors and the achievement of current treatment goals. DESIGN:A community-based, cross-sectional, observational study. SETTING:Hypertension and diabetes outpatient clinics in primary health care, Skara, Sweden. ...

journal_title：Journal of internal medicine

authors： Bøg-Hansen E,Lindblad U,Bengtsson K,Ranstam J,Melander A,Råstam L

更新日期：1998-03-01 00:00:00

abstract：:We describe a 48-year-old woman with recurrent severe hypoglycaemia apparently caused by a paraprotein with insulin-binding capacity. Very high fasting values were found for serum insulin (170 and > 250 mU l-1) as well as for proinsulin 125 pmol l-1 and an insulinoma was suspected. Hypoglycaemia developed after an ora...

journal_title：Journal of internal medicine

authors： Arnqvist HJ,Halban PA,Mathiesen UL,Zahnd G,von Schenck H

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to identify predictors of weight loss in obese men participating in a 2-year behaviour modification programme. DESIGN:Longitudinal, clinical intervention study of a behaviour modifying weight loss program. SETTING:University Hospital, Stockholm, Sweden. SUBJECTS:Forty-four ...

journal_title：Journal of internal medicine

authors： Näslund E,Andersson I,Degerblad M,Kogner P,Kral JG,Rössner S,Hellström PM

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:To study the prognostic value of neutrophil gelatinase-associated lipocalin (NGAL) in chronic heart failure (HF) of ischaemic aetiology. BACKGROUND:Neutrophil gelatinase-associated lipocalin is a marker of kidney injury as well as matrix degradation and inflammation and has previously been shown to be increa...

journal_title：Journal of internal medicine

authors： Nymo SH,Ueland T,Askevold ET,Flo TH,Kjekshus J,Hulthe J,Wikstrand J,McMurray J,Van Veldhuisen DJ,Gullestad L,Aukrust P,Yndestad A

更新日期：2012-05-01 00:00:00

abstract：:The therapeutic effect of an elemental diet (Pepti 2000) and blended normal diet (placebo) was investigated in 43 out-patients with chronic inflammatory bowel disease (IBD); 24 with ulcerative colitis (UC) and 19 with Crohn's disease (CD), in a mild to moderate state of disease activity. A pilot study on healthy volun...

journal_title：Journal of internal medicine

authors： Munkholm Larsen P,Rasmussen D,Rønn B,Munck O,Elmgreen J,Binder V

更新日期：1989-05-01 00:00:00