High frequency of asymptomatic visual field defects in subjects with transient ischaemic attacks or minor strokes.

abstract：OBJECTIVES:Single nucleotide polymorphisms in genes encoding inflammatory molecules may determine genetic profiles associated with increased risk of development and progression of cardiovascular diseases. In this study, we evaluated distribution and reciprocal interaction of a set of functionally important polymorphism...

journal_title：Journal of internal medicine

authors： Flex A,Gaetani E,Angelini F,Sabusco A,Chillà C,Straface G,Biscetti F,Pola P,Castellot JJ Jr,Pola R

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:The major aim of this study was to compare various aspects of carbohydrate, insulin, and lipoprotein metabolism, serum uric acid concentration, and blood pressure in normal subjects stratified on the basis of both plasma insulin concentration and degree of obesity. The hypothesis to be tested was that hyperin...

journal_title：Journal of internal medicine

authors： Zavaroni I,Bonini L,Fantuzzi M,Dall'Aglio E,Passeri M,Reaven GM

更新日期：1994-01-01 00:00:00

abstract：:We observed two patients with hypercholesterolaemia and tendon xanthomas associated with apolipoprotein (apoE-7) E-7, a rare variant of the apoE isoforms. Both suffered from coronary artery disease and had undergone a coronary bypass operation. Their cholesterol levels were 268 and 310 mg dl-1, respectively. Both pati...

journal_title：Journal of internal medicine

authors： Ueyama Y,Nozaki S,Yanagi K,Hiraoka H,Nakagawa T,Sakai N,Jiao S,Yamashita S,Matsuzawa Y

更新日期：1994-02-01 00:00:00

abstract：:It is now well recognized that cardiovascular events (CVE) occur quite commonly, both in the acute phase and in the long-term, in patients with community-acquired pneumonia (CAP). CVE have been noted in up to 30% of patients hospitalized with all-cause CAP. One systematic review and meta-analysis of hospitalized patie...

journal_title：Journal of internal medicine

authors： Feldman C,Normark S,Henriques-Normark B,Anderson R

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:It is well known that pulmonary function is associated with all-cause and cardiovascular (CV) death. Less is known about the association between respiratory symptoms and mortality and whether such an association is independent of physical fitness. In this study, we assessed the association of breathlessness ...

journal_title：Journal of internal medicine

authors： Stavem K,Sandvik L,Erikssen J

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:To analyse the associations between serum gamma-glutamyl transpeptidase activity (GTP) and the components of the metabolic syndrome. DESIGN:Cross-sectional, observational study of hypertensive patients and controls. SETTING:The participating subjects visited the research laboratory of the Department of Inte...

journal_title：Journal of internal medicine

authors： Rantala AO,Lilja M,Kauma H,Savolainen MJ,Reunanen A,Kesäniemi YA

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:To evaluate (i) the demineralizing effect of L-thyroxine (LT4) therapy at doses mildly inhibiting serum thyroid stimulating hormone (TSH) in patients with benign nodular goitre; (ii) the efficacy of treatment on nodule size. DESIGN:Cross-sectional study comparing euthyroid women with nodular goitre treated ...

journal_title：Journal of internal medicine

authors： Baldini M,Gallazzi M,Orsatti A,Fossati S,Leonardi P,Cantalamessa L

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVES:The cell cycle regulator cyclin D1 plays an important role in parathyroid tumourigenesis. The NciI polymorphism in exon 4 has recently been associated with early onset of hereditary nonpolyposis colorectal cancer and is a prognostic indicator of nonsmall cell lung cancer and squamous cell carcinomas. Further...

journal_title：Journal of internal medicine

authors： Correa P,Lundgren E,Rastad J,Akerström G,Westin G,Carling T

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:Peroxidation of lipoproteins may be of critical importance in the development of atherosclerosis. Tocopherol is considered to be the most effective lipid-soluble antioxidant. The main aim of this study was to measure the serum tocopherol concentrations in a Swedish reference population and to relate them to ...

journal_title：Journal of internal medicine

authors： Ohrvall M,Tengblad S,Vessby B

更新日期：1993-07-01 00:00:00

abstract：:Although biofilms have been observed early in the history of microbial research, their impact has only recently been fully recognized. Biofilm infections, which contribute to up to 80% of human microbial infections, are associated with common human disorders, such as diabetes mellitus and poor dental hygiene, but also...

journal_title：Journal of internal medicine

authors： Bjarnsholt T,Buhlin K,Dufrêne YF,Gomelsky M,Moroni A,Ramstedt M,Rumbaugh KP,Schulte T,Sun L,Åkerlund B,Römling U

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:The Cardiovascular Risk in Young Finns Study is an on-going multicentre study of atherosclerosis precursors in Finnish children and young adults. We have collected risk factor data in the 21-year follow-up performed in 2001. The aims of this analysis were to examine the levels, secular trends and east-west d...

journal_title：Journal of internal medicine

authors： Juonala M,Viikari JS,Hutri-Kähönen N,Pietikäinen M,Jokinen E,Taittonen L,Marniemi J,Rönnemaa T,Raitakari OT

更新日期：2004-04-01 00:00:00

abstract：:Apart from being an acute phase reactant, fibrinogen appears to play an important although not widely recognized role in athero-/thrombogenesis. Arteriosclerotic diseases are associated with elevated levels of plasma fibrinogen. Strategies that lower the cardiovascular risk also lower fibrinogen levels. Virtually all ...

journal_title：Journal of internal medicine

authors： Ernst E

更新日期：1990-06-01 00:00:00

abstract：:Ebola virus disease (EVD) is a zoonotic disease that causes severe haemorrhagic fever, with high fatality rates of up to 90% in humans. Today, there is no effective treatment available. Person-to-person transmission occurs through exposure to blood or body fluids, which can threaten other household members and first-l...

journal_title：Journal of internal medicine

authors： Mirazimi A

更新日期：2015-09-01 00:00:00

abstract：:Here, the notion of distributive justice is explored in relation to the introduction and the application of new medical technologies within the clinical setting. The point of departure is that, in the decision making process on what is necessary and fair in patient care, participants will mobilize different ethical mo...

journal_title：Journal of internal medicine

authors： van der Kloot Meijburg HH

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVES:To clarify the mechanisms by which smoking is associated to toxic and nontoxic goitre and thyroid nodules. DESIGN:Cohort study. SETTING:Sweden. SUBJECTS:A cohort of 874,507 parous women identified through the Medical Birth Registry, with smoking behaviour assessed through self-reported information at the ...

journal_title：Journal of internal medicine

authors： Galanti MR,Granath F,Cnattingius S,Ekbom-Schnell A,Ekbom A

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthesis causing endothelial dysfunction, an early sign of atherogenesis. Symmetric dimethylarginine (SDMA) does not inhibit NO synthases. Peripheral arterial disease (PAD) is a systemic indication of atherosclerosis. METHOD...

journal_title：Journal of internal medicine

authors： Böger RH,Endres HG,Schwedhelm E,Darius H,Atzler D,Lüneburg N,von Stritzky B,Maas R,Thiem U,Benndorf RA,Diehm C

更新日期：2011-03-01 00:00:00

abstract：:We studied the effect of sleeping in the head-up tilt (HUT) position, alone and in combination with fludrocortisone, on orthostatic tolerance and blood pressure (BP) in six patients with hypoadrenergic orthostatic hypotension. A high salt diet of 150-200 mmol Na+ d-1 was also administered. Combined treatment reduced o...

journal_title：Journal of internal medicine

authors： Ten Harkel AD,Van Lieshout JJ,Wieling W

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVES:Hip and distal arm fractures are associated with osteoporosis in the postmenopausal female. In diabetic patients, bone mass has been found to be reduced leading to the hypothesis that diabetes is a risk factor for osteoporosis. Whether this has any clinical implication has only been sparsely elucidated. DES...

journal_title：Journal of internal medicine

authors： Melchior TM,Sørensen H,Torp-Pedersen C

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:To assess the relationships between circulating levels of proinflammatory cytokines and adrenocortical hormones and leptin early after stroke. DESIGN:Blood samples were collected four times daily the first two days after stroke, twice daily the next 4 days and four times at day 7. Cognitive function and func...

journal_title：Journal of internal medicine

authors： Johansson A,Ahrén B,Näsman B,Carlström K,Olsson T

更新日期：2000-02-01 00:00:00

abstract：:Pulsatile, intravenous insulin infusion designed to mimic the portal insulin concentrations that emerge physiologically after a meal, has been postulated to improve glucose tolerance in Type 1 (insulin-dependent) diabetic patients. We studied the effects of insulin pulsing (10 i.v. pulses of human insulin of 0.035 U k...

journal_title：Journal of internal medicine

authors： Heinemann L,Sonnenberg GE,Hohmann A,Ritzenhoff A,Berger M,Benn J,Sönksen P,Kelley D,Gerich J,Aoki T

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVES:To investigate the relationship between cardiac repolarization (QT interval duration) and intima media thickness (IMT) of the carotid arteries as surrogate measures of subclinical atherosclerosis. DESIGN:Prospective study with consecutive subjects enrolled in the SAPHIR program (Salzburg Atherosclerosis Pre...

journal_title：Journal of internal medicine

authors： Strohmer B,Pichler M,Iglseder B,Paulweber B

更新日期：2005-03-01 00:00:00

abstract：:Millions of people worldwide receive agents targeting the renin-angiotensin system (RAS) to treat hypertension or statins to lower cholesterol. The RAS and cholesterol metabolic pathways in the brain are autonomous from their systemic counterparts and are interrelated through the cholesterol metabolite 27-hydroxychole...

journal_title：Journal of internal medicine

authors： Petek B,Villa-Lopez M,Loera-Valencia R,Gerenu G,Winblad B,Kramberger MG,Ismail MA,Eriksdotter M,Garcia-Ptacek S

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To examine the feasibility and efficacy of a multifactorial intervention programme directed towards hypercholesterolaemia, smoking, and diabetes mellitus in treated hypertensive patients after more than 3 years' follow-up and to describe the incidence of cardiovascular complications. DESIGN:Open, randomized,...

journal_title：Journal of internal medicine

authors： Agewall S,Wikstrand J,Samuelsson O,Persson B,Andersson OK,Fagerberg B

更新日期：1994-12-01 00:00:00

abstract：:Cardiac troponin assays have become more sensitive over the years leading to the clinical introduction of high-sensitivity cardiac troponin assays in 2010. Their use has revolutionized the assessment of patients with chest pain in the emergency department by allowing earlier rule-in and rule-out of myocardial infarcti...

journal_title：Journal of internal medicine

authors： Holzmann MJ

更新日期：2018-07-01 00:00:00

abstract：:In the mitochondrion, inherited defects have been identified in the electron transport system by which ATP is formed, as well as in the transport and metabolism of fuels. Clinical findings in diseases due to these defects can be related to abnormal accumulations of metabolic intermediates and inadequate or inefficient...

journal_title：Journal of internal medicine

authors： Luft R,Landau BR

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:To study the association between postural hypotension and (i) electrolyte levels and (ii) neurohumoral factors in elderly hypertensive patients using diuretics. DESIGN:Cross-sectional study of patients and controls. SETTING:The subjects were gathered from senior citizen clubs or they were referred to the st...

journal_title：Journal of internal medicine

authors： Luutonen S,Neuvonen P,Ruskoaho H,Räihä I,Rajala T,Antila K,Sourander L

更新日期：1995-04-01 00:00:00

abstract：:Originally isolated from a haematophagous hookworm, recombinant nematode anticoagulant protein c2 (rNAPc2) is an 85-amino acid protein with potent anticoagulant properties. Unlike conventional anticoagulants that attenuate blood coagulation via inhibition of thrombin or activated factor X (FXa) at the downstream porti...

journal_title：Journal of internal medicine

authors： Lee AY,Vlasuk GP

更新日期：2003-10-01 00:00:00

abstract：:The aim of the present study was to determine the incidence of malignant disease (MD) in adult patients with nephrotic syndrome (NS). Eighty-eight consecutive patients (38 females; 50 males; mean age 47 years; range 15-86) seen in a renal clinic in a 13-year period with NS were studied. Eight of the patients had or de...

journal_title：Journal of internal medicine

authors： Lund L,Jacobsen BA,Schmidt EB

更新日期：1989-09-01 00:00:00

abstract：:Breast cancer is not only increasing in the west but also particularly rapidly in eastern countries where traditionally the incidence has been low. The rise in incidence is mainly related to changes in reproductive patterns and lifestyle. These trends could potentially be reversed by defining women at greatest risk an...

journal_title：Journal of internal medicine

authors： Howell A,Astley S,Warwick J,Stavrinos P,Sahin S,Ingham S,McBurney H,Eckersley B,Harvie M,Wilson M,Beetles U,Warren R,Hufton A,Sergeant J,Newman W,Buchan I,Cuzick J,Evans DG

更新日期：2012-04-01 00:00:00

abstract：:Mutations in the cardiac Na+ channel gene SCN5A are responsible for multiple lethal ventricular arrhythmias including Brugada syndrome and congenital long QT syndrome. Here we report a case of Brugada syndrome with ST elevation in the right precordial and inferior leads accompanied by atrial standstill and spontaneous...

journal_title：Journal of internal medicine

authors： Takehara N,Makita N,Kawabe J,Sato N,Kawamura Y,Kitabatake A,Kikuchi K

更新日期：2004-01-01 00:00:00