Percentage tumor necrosis following chemotherapy in neuroblastoma correlates with MYCN status but not survival.

abstract：:To determine treatment outcome using ceftazidime-aminoglycosides in febrile neutropenic children with cancer, the authors conducted a prospective cohort study in 216 episodes. Early and complete responses to antibiotics were 108/216 (50.0%) and 133/216 (61.6%) episodes, respectively. Death, a modification of antibioti...

journal_title：Pediatric hematology and oncology

authors： Laoprasopwattana K,Pruekprasert P,Laosombat V,Wongchanchailert M

更新日期：2007-12-01 00:00:00

abstract：:The Department of Oncology at Hospital Infantil de México Federico Gómez (HIMFG) was the first unit in our country, and one of the first in Latin America, to specialize in the management of children with cancer. The HIMFG is part of the National Institutes of Health of Mexico, and is a reference hospital with research...

journal_title：Pediatric hematology and oncology

authors： Medina-Sanson A,Martínez-Avalos A,Gallegos-Castorena S,Juárez-Villegas LE,González-Montalvo P,Perales-Arroyo A,Gallegos-González E,Ayometzi-Ouchi MT

更新日期：2002-09-01 00:00:00

abstract：:Arsenic trioxide (ATO) has been proven to be highly effective in adults with newly diagnosed or relapsed acute promyelocytic leukemia (APL). Only very limited data are published on the use of ATO as a single agent for first-line therapy of relapsed APL. The authors present a case of a 8-year-old boy with a bone marrow...

journal_title：Pediatric hematology and oncology

authors： Ebinger M,Schwarze CP,Feuchtinger T,Scheel-Walter HG,Lang P,Hildenbrand S,Gessler P,Handgretinger R

更新日期：2011-05-01 00:00:00

abstract：:Endocrine system dysfunctions are the significant complications of excessive iron overload in beta thalassemia patients. The aim of this study was to evaluate the long-term effect of chelation with deferasirox on endocrine complications. The study group consisted of children with beta thalassemia who had been evaluate...

journal_title：Pediatric hematology and oncology

authors： Bilgin BK,Yozgat AK,Isik P,Çulha V,Kacar D,Kara A,Ozbek NY,Yarali N

更新日期：2020-09-01 00:00:00

abstract：:A recently isolated peptide hormone, hepcidin, is thought to be the principal regulator of iron homeostasis. Hepcidin acts by limiting intestinal iron absorption and promoting iron retention in reticuloendothelial cells. Its precursor peptide form is called pro-hepcidin. The aims of this study were to determine serum ...

journal_title：Pediatric hematology and oncology

authors： Tiker F,Celik B,Tarcan A,Kilicdag H,Ozbek N,Gurakan B

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:To describe clinical and CT features of L-asparaginase-associated pancreatitis (L-AP) and to correlate CT grades with clinical parameters. METHODS:A total of 16 children (M:F = 9:7; mean age, 8.1 years) who developed L-AP after L-asparaginase (L-asp) treatment and underwent abdominal CT scan were included. We ...

journal_title：Pediatric hematology and oncology

authors： Oh HJ,Im SA,Lee JW,Chung NG,Cho B

更新日期：2014-10-01 00:00:00

abstract：:An 11-year-old girl with hereditary factor-VII deficiency and her family have been studied for factor VII coagulation activity (VII:C) and factor VII antigen level (VII:Ag). The proband had 11% VII:C, whereas her VII:Ag was at a level that corresponds to about 50% coagulation activity. Forty-two members of the proband...

journal_title：Pediatric hematology and oncology

authors： Svendsen J,Osterud B

更新日期：1987-01-01 00:00:00

abstract：:Malignant rhabdoid tumors (MRT) of soft tissues are aggressive tumors, which can be detected in almost any part of the body. MRT are rare, and very few cases have been reported in the literature. Prognosis of these tumors is extremely poor despite intensive therapy. Some risk factors such as young age or disseminated ...

journal_title：Pediatric hematology and oncology

authors： Hernández-Marqués C,Lassaletta A,Cormenzana M,García-Esparza E,Madero-López L

更新日期：2015-04-01 00:00:00

abstract：:Metastatic osteosarcoma most commonly affects the lungs and other bones. Hepatic metastasis at the time of diagnosis is extremely rare. A 14-year-old boy with synovial sarcoma of the left popliteal fossa was treated with surgical resection, radiotherapy for microscopic residual disease, and 1 year of chemotherapy (vin...

journal_title：Pediatric hematology and oncology

authors： Daw NC,Kaste SC,Hill DA,Kun LE,Pratt CB

更新日期：2001-03-01 00:00:00

abstract：:To evaluate the quantitative aspects of the shift in production from fetal hemoglobin (HbF) to adult hemoglobin (HbA), the HbF and HbA mass were estimated in a preterm infant (gestational age 29 weeks) for 22 weeks after an exchange transfusion the second day of life, leading to an initial HbA% of 100. Up until the es...

journal_title：Pediatric hematology and oncology

authors： Refsum HE,Bechensteen AG,Lindemann R

更新日期：1998-09-01 00:00:00

abstract：UNLABELLED:Intravenous (IV) ferric iron (Fe)-carbohydrate complexes are used for treating Fe deficiency in children with iron-refractory iron-deficiency anemia (IRIDA). An optimal treatment has yet to be determined. There are relatively little publications on the responsiveness to IV iron therapy in children with IRIDA...

journal_title：Pediatric hematology and oncology

authors： Akin M,Atay E,Oztekin O,Karadeniz C,Karakus YT,Yilmaz B,Erdogan F

更新日期：2014-02-01 00:00:00

abstract：:Medulloblastoma (MB) is a cancer of the cerebellum and the most common primary pediatric malignancy of the central nervous system. Classified as a primitive neural ectoderm tumor; it is thought to arise from granule cell precursors in the cerebellum. The standard of care consists of surgery, chemotherapy and age-depen...

journal_title：Pediatric hematology and oncology

authors： Byrd T,Grossman RG,Ahmed N

更新日期：2012-09-01 00:00:00

abstract：:Immune thrombocytopenia (ITP) is a frequently encountered disease in childhood. Recent reports pointed to the benefit of high-dose steroid in ITP treatment since it resulted in a better outcome in a shorter time than IV immunoglobulin therapy. In the authors' clinic, mainly after 1984, megadose methyl prednisolone (MD...

journal_title：Pediatric hematology and oncology

authors： Yetgin S,Yenicesu IC,Ersoy F

更新日期：2005-07-01 00:00:00

abstract：:Outlining the treatment for an unclassifiable lymphoid malignancy is often difficult. A highly undifferentiated lymphomatous mass that relapsed in spite of intense chemotherapy and autologous transplant is reported. At relapse, there was differentiation into myeloid lineage. Though remission was achieved with AML-type...

journal_title：Pediatric hematology and oncology

authors： Anoop P,Lancaster DL,Ethell ME,Potter MN,Wotherspoon A

更新日期：2009-03-01 00:00:00

abstract：:The effectiveness of the different pharmacological agents and different doses of systemic corticosteroids was analyzed. A total of 1109 patients (median age 8 months; F/M: 2.3) with hemangioma, followed up in our unit for 23 years, were evaluated retrospectively. Forty-five of them received systemic corticosteroids. T...

journal_title：Pediatric hematology and oncology

authors： Akyüz C,Yariş N,Kutluk MT,Büyükpamukçu M

更新日期：2001-01-01 00:00:00

abstract：:A newborn infant presented with intraocular tumor that was clinically diagnosed as retinoblastoma and treated by exenteration of the globe. Within a few weeks however, a large abdominal mass was noted, which was found to involve the left kidney and right lobe of liver. Pathologic evaluation of the intraocular mass as ...

journal_title：Pediatric hematology and oncology

authors： Akhtar M,Ali MA,Sackey K,Bakry M,Johnson T

更新日期：1991-01-01 00:00:00

abstract：:Sinovenous thrombosis describes thrombosis in one or more of the cerebral venous sinuses. The incidence of SVT in childhood appears to be highest during the neonatal period. Although plasma level of D-dimer has been shown to be sensitive for the diagnosis of deep vein thrombosis and pulmonary embolism in adult patient...

journal_title：Pediatric hematology and oncology

authors： Karagöl BS,Erdeve O,Fítöz S,Uysal Z,Atasay B,Arsan S

更新日期：2007-07-01 00:00:00

abstract：:The purpose of this study was to retrospectively analyze the clinical presentation, treatment, and outcomes of children with Wilms tumor (WT) and intravascular extension who were treated at a single institution. A retrospective review was conducted of medical records of all children with Wilms tumor and intravascular ...

journal_title：Pediatric hematology and oncology

authors： Aspiazu D,Fernandez-Pineda I,Cabello R,Ramirez G,Alvarez-Madrid A,De Agustin JC

更新日期：2012-02-01 00:00:00

abstract：:It is well known in the literature that cancer creates educationally related barriers for all children, which may or may not contribute to clinically relevant school problems. The goal of this study was to obtain a base rate for the characteristic pattern of school functioning for children with leukemia, so that the c...

journal_title：Pediatric hematology and oncology

authors： Adamoli L,Deasy-Spinetta P,Corbetta A,Jankovic M,Lia R,Locati A,Fraschini D,Masera G,Spinetta JJ

更新日期：1997-03-01 00:00:00

abstract：:Euthyroid sick syndrome is related to profound changes in thyroid metabolism induced by nonthyroidal diseases. To determine whether children with newly diagnosed Hodgkin disease might present thyroid abnormalities and to establish their predictive value, the authors performed regular thyroid function testing. Seven ch...

journal_title：Pediatric hematology and oncology

authors： Mohn A,Di Marzio A,Cerruto M,Angrilli F,Fioritoni C,Chiarelli F

更新日期：2001-04-01 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) is a rare and fatal hematological syndrome that causes a disturbance of the immune system. Overall mortality of HLH is greater than 50% and the majority of patients who die do so within the first 8 weeks of chemotherapy treatment. To find clinical parameters relating to high-ri...

journal_title：Pediatric hematology and oncology

authors： Dao AT,Luong VT,Nguyen TT,Huynh QT,Phan TT,Lam MT,Ngoma AM,Koriyama C

更新日期：2014-04-01 00:00:00

abstract：:Twelve cases of neuroblastoma (NB) (7 boys and 5 girls) and 4 cases of primitive peripheral neuroectodermal tumor (PNET) (3 boys and 1 girl) were investigated for the presence of apoptosis and retinoic acid receptor (RAR) by immunhistochemical method. The apoptotic index in NB was zero or 1% in 8 children and relative...

journal_title：Pediatric hematology and oncology

authors： Farid P,Babosa M,Hauser P,Schuler D,Szende B

更新日期：2000-06-01 00:00:00

abstract：:Invasive fungal infection continues to pose a significant threat to immunocompromised patients, with cerebral aspergillosis being among the most feared ones. The authors describe an adolescent girl with acute lymphoblastic leukemia (ALL) with subsequent acute liver failure, who developed an aspergillus brain abscess. ...

journal_title：Pediatric hematology and oncology

authors： Sterba J,Prochazka J,Ventruba J,Kren L,Valik D,Burgetova D,Mudry P,Skotakova J,Blatny J

更新日期：2005-12-01 00:00:00

abstract：:Acute basophilic leukemia is a distinct entity of Acute Myeloid Leukemia (AML) with primary differentiation to basophils. Increased basophil count has been described in AML cases with translocation t(6;9)(p23;q34) or other chromosomal abnormalities. We describe a 15-year old female teenager with AML and excess periphe...

journal_title：Pediatric hematology and oncology

authors： Servitzoglou M,Grenzelia M,Baka M,Harisi M,Pourtsidis A,Bouhoutsou D,Varvoutsi M,Doganis D,Dana H,Divane A,Kosmidis H

更新日期：2014-03-01 00:00:00

abstract：:Anaplastic lymphoma kinase (ALK) inhibitors such as crizotinib and alectinib have been shown to have significant activity in ALK-rearranged non-small cell lung cancers (NSCLC). There are no data for alectinib's safety or efficacy in younger patients, though it is superior to crizotinib in adult trials. We present a 14...

journal_title：Pediatric hematology and oncology

authors： Balzer BWR,Loo C,Wegner EA,Nath CE,Lee S,Smith C,Lewis CR,Trahair TN,Anazodo AC

更新日期：2018-01-01 00:00:00

abstract：:The authors describe the relation between clamping time and blood volume collected, and two enrichment systems of CD34+ stem cells from umbilical cord blood, to determine an excellent recovery with high proliferate ability and bone marrow reconstitution. After an obstetrician-based cord blood collection, the purificat...

journal_title：Pediatric hematology and oncology

authors： Pafumi C,Bosco P,Cavallaro A,Farina M,Leonardi I,Pernicone G,Bandiera S,Russo A,Giardina P,Chiarenza M,Calogero AE

更新日期：2002-06-01 00:00:00

abstract：:Although survival rates in childhood cancer have distinctly improved, pediatric cancer patients often experience various disease- and treatment-related side effects with long-term consequences. Despite current studies investigating inactivity and limitations in physical functioning and quality of life in pediatric can...

journal_title：Pediatric hematology and oncology

authors： Beulertz J,Bloch W,Prokop A,Baumann FT

更新日期：2013-05-01 00:00:00

abstract：:To determine the effect of recombinant human granulocyte-colony stimulation factor (rhG-CSF) on the immune system, serum immunoglobulins, lymphocyte subsets, and serum cytokines were analyzed in eight pediatric patients with aplastic anemia (AA) during 8-week rhG-CSF therapy. The rhG-CSF was administered either subcut...

journal_title：Pediatric hematology and oncology

authors： Hibi S,Yoshihara T,Nakajima F,Misu H,Mabuchi O,Imashuku S

更新日期：1994-05-01 00:00:00

abstract：:The aim of this study was to evaluate the efficacy and safety of meropenem plus amikacin compared with piperacillin-tazobactam plus netilmicin for initial empirical antibiotic treatment of high-risk febrile neutropenia in children with cancer. Patients with hematologic malignancy (leukemia or stage III/IV non-Hodgkin ...

journal_title：Pediatric hematology and oncology

authors： Aksoylar S,Cetingül N,Kantar M,Karapinar D,Kavakli K,Kansoy S

更新日期：2004-03-01 00:00:00

abstract：:The third International Conference on Immunotherapy in Pediatric Oncology was held in Frankfurt/Main, Germany, October 1-2, 2012. Major topics of the conference included (i) cellular therapies using antigen-specific and gene-modified T cells for targeting leukemia and pediatric solid tumors; (ii) overcoming hurdles an...

journal_title：Pediatric hematology and oncology

authors： Brehm C,Huenecke S,Pfirrmann V,Rossig C,Mackall CL,Bollard CM,Gottschalk S,Schlegel PG,Klingebiel T,Bader P

更新日期：2013-08-01 00:00:00