Successful treatment of aspergillus brain abscess in a child with acute lymphoblastic leukemia and liver failure.

Abstract:

:Invasive fungal infection continues to pose a significant threat to immunocompromised patients, with cerebral aspergillosis being among the most feared ones. The authors describe an adolescent girl with acute lymphoblastic leukemia (ALL) with subsequent acute liver failure, who developed an aspergillus brain abscess. The patient was treated with combined antifungal therapy using amphotericin B local instillation, prolonged systemic amphotericin B colloidal dispersion along with vinca alkaloids-containing chemotherapy, followed by neurosurgical débridement and oral voriconazole in the setting of ongoing antileukemic maintenance chemotherapy. Her ALL remains now in complete remission 30 months from diagnosis, with no evidence of fungal infection.

journal_name

Pediatr Hematol Oncol

authors

Sterba J,Prochazka J,Ventruba J,Kren L,Valik D,Burgetova D,Mudry P,Skotakova J,Blatny J

doi

10.1080/08880010500278665

subject

Has Abstract

pub_date

2005-12-01 00:00:00

pages

649-55

issue

8

eissn

0888-0018

issn

1521-0669

pii

X32524TM115N8RJW

journal_volume

22

pub_type

杂志文章
  • MYCN amplification by differential PCR.

    abstract::A method is described to estimate MYCN (N-myc) oncogene amplification in neuroblastoma by the technique of differential polymerase chain reaction (PCR). The technique is quicker than conventional Southern blotting techniques and does not require radioactive materials. The ability to measure MYCN amplification from sma...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880019309016525

    authors: Huddart SN,Mann JR,McGukin AG,Corbett R

    更新日期:1993-01-01 00:00:00

  • Pediatric oncology at Hospital Infantil de Mexico: fifty-five years of accomplishment.

    abstract::The Department of Oncology at Hospital Infantil de México Federico Gómez (HIMFG) was the first unit in our country, and one of the first in Latin America, to specialize in the management of children with cancer. The HIMFG is part of the National Institutes of Health of Mexico, and is a reference hospital with research...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010290097198

    authors: Medina-Sanson A,Martínez-Avalos A,Gallegos-Castorena S,Juárez-Villegas LE,González-Montalvo P,Perales-Arroyo A,Gallegos-González E,Ayometzi-Ouchi MT

    更新日期:2002-09-01 00:00:00

  • Profiling Loss of Heterozygosity Patterns in a Cohort of Favorable Histology Nephroblastoma Egyptian Patients: What is Consistent With the Rest of the World.

    abstract::According to the Fifth National Wilms Tumor Study (NWTS-5), tumor-specific loss of heterozygosity (LOH) for chromosomes 1p and 16q identifies a subset of patients with Wilms tumor (WT) who despite having favorable histology (FH) have a significantly increased risk of relapse and death. We aimed to find out 1p and 16q ...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880018.2015.1071902

    authors: Fawzy M,Bahanassy A,Samir A,Hafez H

    更新日期:2015-01-01 00:00:00

  • Complications of β-thalassemia intermedia in Iran during 1996-2010 (single-center study).

    abstract::Patients with thalassemia intermedia (TI) experience many complications, of which the incidence varies greatly among cases. Considering the high prevalence of thalassemia in Iran, the study was carried out to determine the frequency of TI complications in Iranian patients and to find possible risk factors for each of ...

    journal_title:Pediatric hematology and oncology

    pub_type: 临床试验,杂志文章

    doi:10.3109/08880018.2011.572144

    authors: Rafsanjani KA,Mafi N,Tafreshi RI

    更新日期:2011-09-01 00:00:00

  • Relapse of primitive mediastinal lymphoma as a myeloid mass following beam autologous transplant and subsequent refractoriness to matched unrelated umbilical cord blood allograft.

    abstract::Outlining the treatment for an unclassifiable lymphoid malignancy is often difficult. A highly undifferentiated lymphomatous mass that relapsed in spite of intense chemotherapy and autologous transplant is reported. At relapse, there was differentiation into myeloid lineage. Though remission was achieved with AML-type...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010902754883

    authors: Anoop P,Lancaster DL,Ethell ME,Potter MN,Wotherspoon A

    更新日期:2009-03-01 00:00:00

  • Secondary malignant neoplasms after childhood cancer.

    abstract::Overall survival from cancer has greatly improved, although it still remains the second leading cause of mortality in the world. This result was achieved through the use of chemotherapy and radiotherapy, which are severely toxic to normal tissues. In the long-term follow-up of cancer patients, the development of secon...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章,评审

    doi:10.3109/08880018.2011.553879

    authors: Varan A,Kebudi R

    更新日期:2011-08-01 00:00:00

  • Infections in childhood acute lymphoblastic leukemia: an analysis of 222 febrile neutropenic episodes.

    abstract::A retrospective analysis was performed on febrile neutropenic episodes in patients with acute lymphoblastic leukemia (ALL) from 1992 to 2002. There were 222 febrile neutropenic episodes in 266 ALL patients with documented ANC < 500/mm(3). Of the 222 episodes, 98 (44%) had documented focus of infection; the rest were f...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010802106564

    authors: Bakhshi S,Padmanjali KS,Arya LS

    更新日期:2008-06-01 00:00:00

  • Somnolence syndrome in a child following 1200-cGy total body irradiation in an unrelated bone marrow transplantation.

    abstract::Neurological complications may occur following intensive chemotherapy and hematopoietic cell transplantation. Postirradiation somnolence syndrome has been observed in children with acute lymphoblastic leukemia who received central nervous system preventive therapy with 1800-2400 cGy cranial irradiation. The authors re...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010050120854

    authors: Miyahara M,Azuma E,Hirayama M,Kobayashi M,Hori H,Komada Y,Masuda H

    更新日期:2000-09-01 00:00:00

  • Does D-dimer predict cerebral sinovenous thrombosis in the newborn?

    abstract::Sinovenous thrombosis describes thrombosis in one or more of the cerebral venous sinuses. The incidence of SVT in childhood appears to be highest during the neonatal period. Although plasma level of D-dimer has been shown to be sensitive for the diagnosis of deep vein thrombosis and pulmonary embolism in adult patient...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010701255769

    authors: Karagöl BS,Erdeve O,Fítöz S,Uysal Z,Atasay B,Arsan S

    更新日期:2007-07-01 00:00:00

  • Ondansetron and tropisetron in the control of nausea and vomiting in children receiving combined cancer chemotherapy.

    abstract::Ondansetron (Zofron, Glaxo) and tropisetron (Navoban, Sandoz) are selective serotonin (5HT3) antagonists that have proven very effective in the prevention of vomiting and nausea in adults and children receiving cancer chemotherapy. This study compared the efficacy of the two agents in the prevention of vomiting and na...

    journal_title:Pediatric hematology and oncology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/088800199277425

    authors: Stiakaki E,Savvas S,Lydaki E,Bolonaki I,Kouvidi E,Dimitriou H,Kambourakis A,Kalmanti M

    更新日期:1999-03-01 00:00:00

  • α-Thalassemia frequency and mutations in children with hypochromic microcytic anemias and relation with β-thalassemia, iron deficiency anemia.

    abstract::The majority of the anemias during childhood are hypochromic and microcytic. The aim of the present study was to determine the status of α-thalassemia mutations and its association with other etiologies, such as iron deficiency anemia (IDA) and β-thalassemia trait, that are frequently seen hypochromic microcytic anemi...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880018.2012.661831

    authors: Gulen H,Hanimeli O,Karaca O,Taneli F

    更新日期:2012-04-01 00:00:00

  • Etoposide in Langerhans cell histiocytosis in children: a preliminary experience.

    abstract::Treatment of Langerhans cell histiocytosis (LCH) is yet to be established. We treated seven patients with etoposide alone at a dose of 100 mg/m2/day for 3 days given every 3 to 4 weeks for six cycles. Three patients had received prior chemotherapy, two patients were less than 2 years of age, and two had liver dysfunct...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880019609030806

    authors: Basade MM,Nair CN,Kurkure PA,Pai SK,Advani SH

    更新日期:1996-03-01 00:00:00

  • Increased urinary HVA levels in neuroblastoma screens related to diet, not tumor.

    abstract::At present, urinary vanillylmandelic acid (VMA) and/or homovanillic acid (HVA), metabolites of catecholamines, are the most sensitive diagnostic markers of neuroblastoma. They can be measured by the high-performance liquid chromatographic method, which has been used to screen for neuroblastoma in infants in Japan. Fro...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880019709030914

    authors: Numata K,Kusui H,Kawakatsu H,Kizaki Z,Sawada T

    更新日期:1997-11-01 00:00:00

  • Successful multimodal therapy for kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon: case report and review of the literature.

    abstract::We present the management challenge provided by a patient with kaposiform hemangioendothelioma associated with Kasabach-Merritt phenomenon. A female child presented at 14 months of age with an ecchymotic swelling of her right upper arm and axilla. Subsequently, she developed profound thrombocytopenia and hypofibrinoge...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章,评审

    doi:10.3109/08880019809014013

    authors: Blei F,Karp N,Rofsky N,Rosen R,Greco MA

    更新日期:1998-07-01 00:00:00

  • Post-radiotherapy apparent diffusion coefficient (ADC) in children and young adults with high-grade gliomas and diffuse intrinsic pontine gliomas.

    abstract::Objectives: Diffusion-weighted magnetic resonance imaging (DW-MRI) offers potential to monitor response and predict survival in high-grade gliomas (HGG) and diffuse intrinsic pontine gliomas (DIPG). We hypothesized that post-radiotherapy DW-MRI may provide prognostic imaging biomarkers in children and young adults wit...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880018.2019.1592267

    authors: Carceller F,Jerome NP,Fowkes LA,Khabra K,Mackinnon A,Bautista F,Marshall LV,Vaidya S,Mandeville H,Morgan V,Leach MO,Koh DM

    更新日期:2019-03-01 00:00:00

  • Amantadine in chronic granulomatous disease.

    abstract::Chronic granulomatous disease (CGD) is a rare genetically determined immunodeficiency. Neutrophils from CGD patients show a defective killing of phagocytosed fungi and bacteria, due not only to an impairment in oxidative burst, but also to absence of normal pH value within phagocytic vacuole following phagocytosis. Be...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010590907267

    authors: Granzotto M,Leone V,Lepore L,Zerial M,Tommasini A,Ciambra R,Gombac F,Ventura A

    更新日期:2005-03-01 00:00:00

  • Usefulness of power Doppler ultrasonography and superparamagnetic iron oxide enhanced magnetic resonance imaging for diagnosis of focal nodular hyperplasia of the liver after treatment of neuroblastoma.

    abstract::Focal nodular hyperplasia (FNH) of the liver is rare in children, and it is usually diagnosed through a biopsy of the liver or hepatectomy. The authors report a case of a 10-year-old girl with multiple focal nodular hyperplasia lesions of the liver after the completion of tumor therapy for advanced neuroblastoma, and ...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880010903464206

    authors: Sugito K,Kusafuka T,Kawashima H,Uekusa S,Furuya T,Ohashi K,Inoue M,Ikeda T,Koshinaga T,Maebayashi T

    更新日期:2010-04-01 00:00:00

  • Daily Bathing with Chlorhexidine and Its Effects on Nosocomial Infection Rates in Pediatric Oncology Patients.

    abstract::Infections remain a serious complication in pediatric oncology patients. To determine if daily bathing with Chlorhexidine gluconate can decrease the rate of nosocomial infection in pediatric oncology patients, we reviewed rates of infections in pediatric oncology patients over a 14-month span. Intervention group recei...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880018.2015.1013588

    authors: Raulji CM,Clay K,Velasco C,Yu LC

    更新日期:2015-01-01 00:00:00

  • Shift from fetal to adult hemoglobin production in a preterm infant after exchange transfusion: a quantitative approach.

    abstract::To evaluate the quantitative aspects of the shift in production from fetal hemoglobin (HbF) to adult hemoglobin (HbA), the HbF and HbA mass were estimated in a preterm infant (gestational age 29 weeks) for 22 weeks after an exchange transfusion the second day of life, leading to an initial HbA% of 100. Up until the es...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880019809016572

    authors: Refsum HE,Bechensteen AG,Lindemann R

    更新日期:1998-09-01 00:00:00

  • Wiskott-Aldrich syndrome: Two case reports with a novel mutation.

    abstract:BACKGROUND:The Wiskott-Aldrich syndrome (WAS) is X-linked recessive disorder associated with microplatelet thrombocytopenia, eczema, infections, and an increased risk of autoimmunity and lymphoid neoplasia. The originally described features of WAS include susceptibility to infections, microthrombocytopenia, and eczema....

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880018.2017.1397072

    authors: Kamuran K,Çetin M,Geylan H,Karaman S,Demir N,Yurekturk E,Yavuz İ,Yavuz G,Tuncer O

    更新日期:2017-08-01 00:00:00

  • Association of maternal education with the neuroblastoma susceptibility in children: a meta-analysis.

    abstract::Maternal education might be an important factor for the neuroblastoma risk in children, but it was conflicting. This meta-analysis was performed to evaluate the relationship between maternal education and neuroblastoma susceptibility and to explore whether maternal education was an important indicator to be associated...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章,meta分析

    doi:10.3109/08880018.2012.742605

    authors: Wang P,Liao N,Liao XH,Liang B,Huang CX,Li W

    更新日期:2013-02-01 00:00:00

  • Triosephosphate isomerase deficiency in a child with congenital hemolytic anemia and severe hypotonia.

    abstract::A discussion of a 5-year-old child with congenital hemolytic anemia and severe hypotonia caused by triosephosphate (TPI) deficiency is presented. The complexities in the diagnosis and management of this condition is discussed and the relevant literature is reviewed. ...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880019809018318

    authors: Linarello RE,Shetty AK,Thomas T,Warrier RP

    更新日期:1998-11-01 00:00:00

  • Soft tissue density variations in thalassemia major: a possible pitfall in lumbar bone mineral density measurements by dual-energy X-ray absorptiometry.

    abstract::Osteoporosis is common in patients with thalassemia major. A 16-year-old patient with thalassemia major was referred for evaluation of osteoporosis. The results of dual-energy X-ray absorptiometry in a patient with thalassemia major are presented. The patient underwent measurements of the spine in both AP and lateral ...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010500278707

    authors: Yildiz M,Canatan D

    更新日期:2005-12-01 00:00:00

  • Endemic Burkitt Lymphoma: Long-term Outcome in 87 Patients Who Presented With Paraplegia in Cameroon.

    abstract::The reported long-term outcome of endemic Burkitt lymphoma (eBL) patients who present with paraplegia is largely unknown. Records of BL patients treated with comparable short-interval cyclophosphamide chemotherapy schedules between 2004 and 2014 at three Baptist mission hospitals in Cameroon were reviewed. Survivors w...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章,多中心研究

    doi:10.3109/08880018.2015.1085936

    authors: Hesseling PB,Mbah G,Kouya F,Kimbi C,Nfor P,Kaah J,Kuruvilla R,Best A,Wharin P

    更新日期:2015-01-01 00:00:00

  • Vincristine and irinotecan in children with relapsed hepatoblastoma: a single-institution experience.

    abstract:PURPOSE:This study was to determine the efficacy of vincristine and irinotecan in children with relapsed hepatoblastoma (HB). METHODS:A total of 10 patients with relapsed HB were enrolled. Three patients were excluded. Patients received irinotecan 50 mg/m(2)/day, day 1-5 and vincristine 1.5 mg/m(2)/day, day 1, repeate...

    journal_title:Pediatric hematology and oncology

    pub_type: 临床试验,杂志文章

    doi:10.3109/08880018.2014.909913

    authors: Zhang YT,Feng LH,Zhong XD,Wang LZ,Chang J

    更新日期:2015-02-01 00:00:00

  • Homozygous 23-bp insertion of endothelial protein c receptor gene in a child with fatal sepsis.

    abstract::Endothelial protein C receptor (EPCR) is primarily localized on the endothelial cells of large blood vessels and is very low or absent in the microvascular endothelium of most tissues. EPCR augments the thrombin/thrombomodulin-dependent activation of protein C by 5- to 20-fold. EPCR appears to be physiologically signi...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010701198811

    authors: Kendirli T,Ciftçi E,Ince E,Yurdakul E,Kansu A,Akar N

    更新日期:2007-04-01 00:00:00

  • Elevated p53 protein expression; a predictor of relapse in rare chronic myeloid malignancies in children?

    abstract:BACKGROUND:Alterations in the tumor suppressor gene TP53 have been associated with poor outcome in adult hematological malignancies. We have earlier reported an increased expression of the TP53 encoded protein p53, in bone marrow samples from pediatric patients with aggressive leukemia. Our aim was now to evaluate p53 ...

    journal_title:Pediatric hematology and oncology

    pub_type: 临床试验,杂志文章

    doi:10.3109/08880018.2014.898723

    authors: Honkaniemi E,Mattsson K,Barbany G,Sander B,Gustafsson B

    更新日期:2014-05-01 00:00:00

  • Hematologic phenotype of the mutations IVS1-n6 (T-->C), IVS1-n110 (G-->A), and CD39 (C-->T) in carriers of beta-thalassemia in Greece.

    abstract::The hematologic phenotype was characterized in heterozygotes for three of the most common beta-thalassemia mutations in the Greek population. The study included 17 carriers of beta++ IVS1-n6 (T-->C), 21 carriers of beta+ IVS1-n110 (G-->A), and 17 carriers of beta 0 CD39 (C-->T). The 55 beta-thalassemia heterozygotes w...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880019409141689

    authors: Stefanis L,Kanavakis E,Traeger-Synodinos J,Tzetis M,Metaxotou-Mavromati A,Kattamis C

    更新日期:1994-09-01 00:00:00

  • Nonossifying fibromyxoid tumor of soft tissue.

    abstract::A firm, painless tumor of the temporal region was excised in a 3-year-old girl. The diagnosis of nonossifying fibromyxoid tumor was established on pathologic examination, which showed that most of the cells formed cords and tubulelike structures in a myxoid background. Bone and osteoid were lacking. The child is free ...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880019409140547

    authors: Leray V,Gosseye S,Sempoux C,Ninane J,Vanwijck R

    更新日期:1994-07-01 00:00:00

  • A randomized study of ondansetron syrup in children: evaluation of taste acceptability and tolerance.

    abstract::Ondansetron, a highly selective 5-HT3 receptor antagonist, is available in an intravenous (IV) formulation and tables, but syrup would be particularly useful in children. As chemotherapy can affect taste perceptions, this study was undertaken to determine the preference between two flavors of ondansetron syrup in chil...

    journal_title:Pediatric hematology and oncology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.3109/08880019609030816

    authors: Stevens R,Votan B,Lane R,Schaison G,Hewitt M,Kohler J,Thyss A

    更新日期:1996-03-01 00:00:00