Amantadine in chronic granulomatous disease.

abstract：BACKGROUND:The authors report the experience at the Children's Hospital Los Angeles with brain tumors diagnosed before 6 months of age, describing the characteristics of the patients, their tumors, treatment strategies, and prognostic factors. METHODS:Thirty-three children who were identified between 1979 and 2005 wer...

journal_title：Pediatric hematology and oncology

authors： Serowka K,Chiu Y,Gonzalez I,Gilles F,McComb G,Krieger M,Dhall G,Britt B,Ji L,Sposto R,Finlay JL

更新日期：2010-03-01 00:00:00

abstract：:Methotrexate (MTX) is an antimetabolite with a major role in the treatment of acute lymphoblastic leukaemia (ALL). The authors report the management of a 9-year-old boy who developed an anaphylactoid reaction to high-dose MTX infusion, after a first challenge with intrathecal administration, during induction therapy f...

journal_title：Pediatric hematology and oncology

authors： Caldeira T,Costa V,Silva I,Oliva T,Norton L

更新日期：2008-03-01 00:00:00

abstract：:The treatment of a child with a relapsed state acute leukemia after allogeneic stem cell transplantation (allo-SCT) is a challenge. The authors report about a child with an acute myelogenous leukemia (AML), which relapsed after allo-SCT despite immunological intervention. It was further treated with a second line chem...

journal_title：Pediatric hematology and oncology

authors： Hartwig M,Weigel S,Bernig T,Bader P,Dölken R,Beck J

更新日期：2007-03-01 00:00:00

abstract：:This study examined both the endogenous and exogenous (therapy-related) pharmacokinetics of the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) in neutropenic children with solid and systemic malignancies. The daily endogenous GM-CSF serum concentration before application was 29 pg/mL. During the 10...

journal_title：Pediatric hematology and oncology

authors： Müller CE,Mukodzi S,Reddemann H

更新日期：1999-11-01 00:00:00

abstract：:Factor XIII deficiency is a very rare bleeding disorder. We report here on the clinical outcome of a young child with intracranial bleeding due to factor XIII deficiency. Clinicians should bear in mind that severe factor XIII deficiency is associated with a significant risk of unexpected intracranial hemorrhage (ICH)....

journal_title：Pediatric hematology and oncology

authors： Bay A,Sirikci A,Dogan A,Leblebisatan G,Yilmaz F

更新日期：2013-11-01 00:00:00

abstract：:To evaluate the quantitative aspects of the shift in production from fetal hemoglobin (HbF) to adult hemoglobin (HbA), the HbF and HbA mass were estimated in a preterm infant (gestational age 29 weeks) for 22 weeks after an exchange transfusion the second day of life, leading to an initial HbA% of 100. Up until the es...

journal_title：Pediatric hematology and oncology

authors： Refsum HE,Bechensteen AG,Lindemann R

更新日期：1998-09-01 00:00:00

abstract：:Three children with malignant solid tumors developed hyponatremia with renal sodium wasting associated with other signs of tubular dysfunction, such as hypokalemia or hypomagnesemia, a few days after cis-diammine dichloroplatinum (CDDP) administration. The normalization of serum electrolyte disturbances was obtained w...

journal_title：Pediatric hematology and oncology

authors： Vassal G,Rubie H,Kalifa C,Hartmann O,Lemerle J

更新日期：1987-01-01 00:00:00

abstract：AIM:In recent years, survival rates of childhood cancers have significantly increased, and occurrence of long-term adverse late effects (eg, insulin resistance, diabetes mellitus, metabolic syndrome, hypertension) has become increasingly important. Early diagnosis of obesity/hypertension in childhood is essential to av...

journal_title：Pediatric hematology and oncology

authors： Guler E,Col N,Buyukcelik M,Balat A

更新日期：2018-02-01 00:00:00

abstract：:Clear cell sarcoma of the kidney (CCSK) has been classified as high risk tumour in the previous UK and international Wilms tumor studies. The current Society of Paediatric Oncology (SIOP) trial, UK version, advocates chemotherapy including doxorubicin prior to nephrectomy. Pathological staging and histology of the res...

journal_title：Pediatric hematology and oncology

authors： Ng A,Jenkinson H,Morland B,Grundy R

更新日期：2005-04-01 00:00:00

abstract：:Immune thrombocytopenia (ITP) is a frequently encountered disease in childhood. Recent reports pointed to the benefit of high-dose steroid in ITP treatment since it resulted in a better outcome in a shorter time than IV immunoglobulin therapy. In the authors' clinic, mainly after 1984, megadose methyl prednisolone (MD...

journal_title：Pediatric hematology and oncology

authors： Yetgin S,Yenicesu IC,Ersoy F

更新日期：2005-07-01 00:00:00

abstract：:Ten children receiving 5 to 6 week courses of radiotherapy after brain tumor surgery were given ondansetron treatment for persistent nausea and emesis. All patients continued the ondansetron treatment until the end of their radiotherapy course. Nausea, emesis, appetite, and adverse events were scored throughout the on...

journal_title：Pediatric hematology and oncology

authors： Lippens RJ,Broeders GC

更新日期：1996-05-01 00:00:00

abstract：:During the last 5 years massive chemotherapy and autologous bone marrow transplantation have been increasingly explored in the treatment of pediatric solid tumors, mainly for neuroblastoma, Ewing's sarcoma, rhabdomyosarcoma, Wilms' tumor, germ cell tumors, osteosarcoma, and retinoblastoma. Although the disease course ...

journal_title：Pediatric hematology and oncology

authors： Yaniv I,Bouffet E,Irle C,Negrier S,Biron P,Favrot M,Philip I,Brunat-Mentigny M,Philip T

更新日期：1990-01-01 00:00:00

abstract：:Background: Preclinical studies show that TLR9 agonists can eradicate leukemia by induction of immune responses in vivo against AML and ALL. These studies demonstrated that TLR9 agonists induce an immediate NK response followed by adaptive T and B cells responses resulting in long term anti-leukemia immunity. Methods:...

journal_title：Pediatric hematology and oncology

authors： Ronsley R,Kariminia A,Ng B,Mostafavi S,Reid G,Subrt P,Hijiya N,Schultz KR

更新日期：2019-11-01 00:00:00

abstract：:Hyperleukocytosis in patients with leukemia is associated with early mortality, especially due to the pulmonary and neurological complications of leukostasis. The prompt use of leukapheresis may improve patients' survival in the initial treatment period. The medical records of all previously untreated acute leukemia p...

journal_title：Pediatric hematology and oncology

authors： Yilmaz D,Karapinar B,Karadaş N,Duyu M,Yazici P,Ay Y,Balkan C,Aydinok Y,Kavakli K

更新日期：2014-05-01 00:00:00

abstract：:Primary diffuse leptomeningeal glioneuronal tumors (DLGNT) are rare tumors, recently recognized as a unique entity based on their unique pathologic and clinical characteristics. We report three cases of DLGNT and compare their clinical characteristics and presentation with other reported cases, and with primary leptom...

journal_title：Pediatric hematology and oncology

authors： Abongwa C,Cotter J,Tamrazi B,Dhall G,Davidson T,Margol A

更新日期：2020-04-01 00:00:00

abstract：:An 11-year-old girl with hereditary factor-VII deficiency and her family have been studied for factor VII coagulation activity (VII:C) and factor VII antigen level (VII:Ag). The proband had 11% VII:C, whereas her VII:Ag was at a level that corresponds to about 50% coagulation activity. Forty-two members of the proband...

journal_title：Pediatric hematology and oncology

authors： Svendsen J,Osterud B

更新日期：1987-01-01 00:00:00

abstract：:Medulloblastoma (MB) is a cancer of the cerebellum and the most common primary pediatric malignancy of the central nervous system. Classified as a primitive neural ectoderm tumor; it is thought to arise from granule cell precursors in the cerebellum. The standard of care consists of surgery, chemotherapy and age-depen...

journal_title：Pediatric hematology and oncology

authors： Byrd T,Grossman RG,Ahmed N

更新日期：2012-09-01 00:00:00

abstract：:Tolerance of full-dose methotrexate/6-mercaptopurine (MTX/6MP) maintenance therapy for childhood acute lymphoblastic leukemia (ALL) without side effects could reflect insufficient systemic drug exposure, and drug withdrawals due to toxicity might reduce the chance of cure. The present study included 122 children with ...

journal_title：Pediatric hematology and oncology

authors： Schmiegelow K

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:Venous thrombotic events (VTE) are a well-recognized complication in pediatric cancer patients. Population-based data on the incidence and characteristics of VTE in all pediatric cancer patients are limited. This information is crucial to identify patients at high risk and design targeted interventions accord...

journal_title：Pediatric hematology and oncology

authors： Asyyed Z,MacDonald T,Digout C,Kulkarni K

更新日期：2017-03-01 00:00:00

abstract：:This study evaluates the efficacy of heparinization in prolonging patency of arterial and central venous catheters in children. A randomized double-blind trial in a tertiary 10-bed pediatric intensive care unit was used to evaluate 300 children (age older than 4 weeks, younger than 18 years). Trial medication consiste...

journal_title：Pediatric hematology and oncology

authors： de Neef M,Heijboer H,van Woensel JB,de Haan RJ

更新日期：2002-12-01 00:00:00

abstract：:Although survival rates in childhood cancer have distinctly improved, pediatric cancer patients often experience various disease- and treatment-related side effects with long-term consequences. Despite current studies investigating inactivity and limitations in physical functioning and quality of life in pediatric can...

journal_title：Pediatric hematology and oncology

authors： Beulertz J,Bloch W,Prokop A,Baumann FT

更新日期：2013-05-01 00:00:00

abstract：:Bloodstream infections (BSI) represent one of the most serious complications in patients in the hematology-oncology unit. In this study, the prevalence, distribution, drug sensitivity profiles, and clinical outcome of BSI were analyzed in pediatric patients with hematological malignancies. Patients admitted to the ped...

journal_title：Pediatric hematology and oncology

authors： Chen S,Liu S,Yuan X,Mai H,Lin J,Wen F

更新日期：2019-11-01 00:00:00

abstract：:A 7-year-old boy with prolonged and marked leukopenia diagnosed at 6 months of age is described. The polymorphonuclear cells presented no hypersegmented nuclei or concentrated nuclear chromatin, although vacuolated myeloid cells appeared in bone marrow smears. Neutrophils reversed in response to administration of G-CS...

journal_title：Pediatric hematology and oncology

authors： Arai J,Wakiguchi H,Hisakawa H,Kubota H,Kurashige T

更新日期：2000-03-01 00:00:00

abstract：:The aim of the study is to evaluate the etiologic and clinical characteristics, treatment regimens, and outcome of the patients with intracranial tumors presenting with central diabetes insipidus (DI). Sixty-nine patients with intracranial tumors presenting with central DI between 1972 and 2012 were retrospectively ev...

journal_title：Pediatric hematology and oncology

authors： Varan A,Atas E,Aydın B,Yalçın B,Akyüz C,Kutluk T,Büyükpamukçu M

更新日期：2013-10-01 00:00:00

abstract：:Twenty-eight children with HSP and 79 healthy children were entered into study. Activities of protein C, free-protein S and antithrombin, activated protein C resistance, levels of fibrinogen. D-dimer, thrombin-antithrombin complex (TAT), prothrombin fragments 1 + 2 (PF(1+2)), and von Willebrand factor antigen (vWAg) a...

journal_title：Pediatric hematology and oncology

authors： Yilmaz D,Kavakli K,Ozkayin N

更新日期：2005-01-01 00:00:00

abstract：:A pheochromocytoma was diagnosed in a 14-year-old boy developing hypertension after treatment with imipramine for primary nocturnal enuresis. The mechanism of action is assumed to be an inhibition of the neuronal uptake of catecholamines being released in large quantities from the tumor. The diagnosis of pheochromocyt...

journal_title：Pediatric hematology and oncology

authors： Birkebaek NH,Perrild BD

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:Physiologic uptake of 18F-fluorodeoxyglucose (FDG) in brown adipose tissue (adipose tissue) of cancer patients may confound interpretation of positron emission tomography (PET) scans. Uptake in adipose tissue occurs in up to half of pediatric oncology patients undergoing PET scans, and is especially common in...

journal_title：Pediatric hematology and oncology

authors： George A,Sinha P,Conrad G,Memon AA,Dressler EV,Wagner LM

更新日期：2017-04-01 00:00:00

abstract：:In 33 children, 23 with acute lymphoblastic leukemia (ALL) and 10 with solid tumors, the phenotype of the enzyme adenosine deaminase (ADA) was detected in the erythrocytes by electrophoresis in cellulose acetate. In all children the ADA enzyme activity was also determined in the plasma by spectrophotometry at the onse...

journal_title：Pediatric hematology and oncology

authors： Hatzistilianou M,Athanassiadou F,Catriu D,Makedou A,Hitoglou S,Papaeconomou A

更新日期：1996-07-01 00:00:00

abstract：:Advancements in surgery, radiotherapy, and chemotherapy have greatly improved the cures rates for children with Wilms tumor. However, a number of therapy-related late effects have been observed in long-term survivors. Generally, late complications are a consequence of treatment type and intensity; the use of radiother...

journal_title：Pediatric hematology and oncology

authors： Wright KD,Green DM,Daw NC

更新日期：2009-09-01 00:00:00

abstract：:Thrombo-embolism in childhood is a multifactorial disorder. The present study is a case-control study that investigated the role of genetic and acquired risk factors in 60 children with thrombosis and compared the results with the controls. Acquired and inherited risk factors precipitating thrombosis were present in 7...

journal_title：Pediatric hematology and oncology

authors： Günes AM,Baytan B,Günay U

更新日期：2006-07-01 00:00:00