Autologous bone marrow transplantation in pediatric solid tumors.

abstract：:Twelve cases of neuroblastoma (NB) (7 boys and 5 girls) and 4 cases of primitive peripheral neuroectodermal tumor (PNET) (3 boys and 1 girl) were investigated for the presence of apoptosis and retinoic acid receptor (RAR) by immunhistochemical method. The apoptotic index in NB was zero or 1% in 8 children and relative...

journal_title：Pediatric hematology and oncology

authors： Farid P,Babosa M,Hauser P,Schuler D,Szende B

更新日期：2000-06-01 00:00:00

abstract：:Few studies have been performed during adolescents' cancer treatment to evaluate its interference on health-related quality of life (HRQL). The purpose of this prospective cohort study was to evaluate adolescents' HRQL during cancer treatment. The Health Utilities Index (HUI) was used for scoring. Forty-five individua...

journal_title：Pediatric hematology and oncology

authors： Rodrigues KE,Machado ST,Ferreira MA,Martins TF,Viana MB,Oliveira BM

更新日期：2013-05-01 00:00:00

abstract：:The authors report their experience with 70 pediatric patients with spinal cord compression (SCC) due to malignancies identified among 898 patients with solid tumors. An extradural tumor was the most frequent cause of SCC (71%); 54% of these were soft tissue sarcomas and neuroblastoma. Most intradural tumors (70%) wer...

journal_title：Pediatric hematology and oncology

authors： Pollono D,Tomarchia S,Drut R,Ibañez O,Ferreyra M,Cédola J

更新日期：2003-09-01 00:00:00

abstract：:Euthyroid sick syndrome is related to profound changes in thyroid metabolism induced by nonthyroidal diseases. To determine whether children with newly diagnosed Hodgkin disease might present thyroid abnormalities and to establish their predictive value, the authors performed regular thyroid function testing. Seven ch...

journal_title：Pediatric hematology and oncology

authors： Mohn A,Di Marzio A,Cerruto M,Angrilli F,Fioritoni C,Chiarelli F

更新日期：2001-04-01 00:00:00

abstract：:We evaluated serum C-reactive protein (CRP) level and serum sodium concentration as early indicators of bacteremia in neutropenic children in two different series in 1983-1984 (49 bacteremias) and 1989-1990 (29 bacteremias). During the earlier period, the goal was to avoid unnecessary antimicrobial therapy. Currently ...

journal_title：Pediatric hematology and oncology

authors： Riikonen P,Saarinen UM,Perkkiö M,Hovi L,Siimes MA

更新日期：1992-10-01 00:00:00

abstract：:Brucellosis produces a variety of nonspecific hematologic abnormalities. Hematologic complications of mild anemia and leukopenia have been frequently associated with acute brucellosis, but pancytopenia is less frequently seen. In this study, records of children with brucellosis aged under or equal to 16 years, admitte...

journal_title：Pediatric hematology and oncology

authors： Akbayram S,Dogan M,Akgun C,Peker E,Parlak M,Caksen H,Oner AF

更新日期：2011-04-01 00:00:00

abstract：:Outcomes in pediatric B-Non-Hodgkin Lymphoma (B NHL) have improved with intensive chemotherapy protocols, with long-term survival now over 80%. However, long-term adverse effects of therapy and poor outcomes for patients who relapse remain challenges. In this study, we aimed to evaluate the potential risks and benefit...

journal_title：Pediatric hematology and oncology

authors： Eissa HM,Allen CE,Kamdar K,Simko S,Goradia P,Dreyer Z,Steuber P,McClain KL,Guillerman RP,Bollard CM

更新日期：2014-04-01 00:00:00

abstract：:One of the causes of the childhood anemia is gastrointestinal system bleeding, which rarely results from parasites. The authors report on a 3-year-old boy with severe anemia and a history of hematemesis. While they were investigating the cause of the anemia and the hematemesis, a leech showing itself in the nasal pass...

journal_title：Pediatric hematology and oncology

authors： Demirören K,Calişkan U

更新日期：2003-10-01 00:00:00

abstract：:We present the case of a female newborn with life-threatening bleeding of a ruptured infantile fibrosarcoma (IFS) and consecutive multiorgan dysfunction syndrome shortly after birth. After stabilization, the tumor could be treated without amputation due to surgery, laser therapy, and chemotherapy. The patient is free ...

journal_title：Pediatric hematology and oncology

authors： Kerl K,Nowacki M,Leuschner I,Masjosthusmann K,Frühwald MC

更新日期：2012-09-01 00:00:00

abstract：:Parvovirus B19 (PVB19) is the causative agent of infectious erythema. In healthy children the virus causes transient erythroid aplasia, whereas in children with chronic hemolytic anemias it can cause severe aplastic crises, and in immunodeficient individuals it can produce chronic red cell aplasia. If contracted durin...

journal_title：Pediatric hematology and oncology

authors： Miniero R,Dalponte S,Linari A,Saracco P,Testa A,Musiani M

更新日期：1996-11-01 00:00:00

abstract：:Since 1981, the Children's Cancer and Leukemia Study Group (CCLSG) has developed a series of protocols for treatment of acute lymphoblastic leukemia (ALL) in childhood. In the first randomized controlled study of the 811 protocol (1981-1983) a comparison of conventional daily 6-mercaptopurine and methotrexate with a p...

journal_title：Pediatric hematology and oncology

authors： Koizumi S,Fujimoto T,Oka T,Watanabe S,Kikuta A,Tsuchiya T,Matsushita T,Asami K,Yanase T,Mimaya J,Ohta S,Miyake M,Nishikawa K,Furuyama T,Yamamura Y,Takaue Y,Ninomiya T,Shimokawa T,Iwai A,Ishida Y,Ariyoshi N,Kimur

更新日期：1997-01-01 00:00:00

abstract：:Unexplained menorrhagia and hematuria occurred in a 13-year-old female with a mild inherited platelet disorder who had never experienced prior bleeding as a result of this disorder. An intensive search revealed that this patient was receiving coumadin that was given by the mother. In addition, the mother drew large vo...

journal_title：Pediatric hematology and oncology

authors： Souid AK,Korins K,Keith D,Dubansky S,Sadowitz PD

更新日期：1993-07-01 00:00:00

abstract：:To determine the effect of recombinant human granulocyte-colony stimulation factor (rhG-CSF) on the immune system, serum immunoglobulins, lymphocyte subsets, and serum cytokines were analyzed in eight pediatric patients with aplastic anemia (AA) during 8-week rhG-CSF therapy. The rhG-CSF was administered either subcut...

journal_title：Pediatric hematology and oncology

authors： Hibi S,Yoshihara T,Nakajima F,Misu H,Mabuchi O,Imashuku S

更新日期：1994-05-01 00:00:00

abstract：:Although most common in tropical regions, population migration has meant that sickle cell disease is now one of the most prevalent genetic diseases worldwide. The issues and challenges faced by physicians and patients have been discussed by an international group of experts representing 4 key regions: the USA, Europe,...

journal_title：Pediatric hematology and oncology

authors： Vichinsky EP,Ohene-Frempong K,Thein SL,Lobo CL,Inati A,Thompson AA,Smith-Whitley K,Kwiatkowski JL,Swerdlow PS,Porter JB,Marks PW

更新日期：2011-03-01 00:00:00

abstract：:Down syndrome (DS) is an important risk factor associated with acute leukemia (AL). The presence of polymorphisms that reduce 5,10-methylenetetrahydrofolate reductase (MTHFR) activity has been linked to the multifactorial leukemogenic process. The authors have conducted a study to test whether 677C-->T and/or 1298A-->...

journal_title：Pediatric hematology and oncology

authors： Amorim MR,Zanrosso CW,Magalhães IQ,Pereira SC,Figueiredo A,Emerenciano M,Pinheiro VR,d'Andréa ML,Orioli IM,Koifman S,Pombo-de-Oliveira MS

更新日期：2008-12-01 00:00:00

abstract：:A 2-year-old girl with acute lymphoblastic leukemia (ALL) showing a t(4;11)(q21;q23) karyotype underwent allogeneic bone marrow transplantation (BMT) with the conditioning regimen of L-PAM (70 mg/m2/d for 3 days), busulfan (140 mg/m2/d for 2 days), and total body irradiation (12 Gy). On day 57, the patient developed p...

journal_title：Pediatric hematology and oncology

authors： Takanashi M,Hibi S,Todo S,Sawada T,Tsunamoto K,Imashuku S

更新日期：1998-01-01 00:00:00

abstract：:Fanconi's anemia is an autosomal recessive disorder characterized by progressive pancytopenia and congenital malformation of the skeleton. This study investigated the oral health status of 15 children with Fanconi's anemia, including oral lesions, gingival and periodontal status, and dental abnormalities. All children...

journal_title：Pediatric hematology and oncology

authors： Açikgöz A,Ozden FO,Fisgin T,Açikgöz G,Duru F,Yarali N,Albayrak D

更新日期：2005-09-01 00:00:00

abstract：:Infantile hemangioendothelioma is the most common hepatic vascular tumor in infants less than 6 months of age, with a prevalence of 1%. Serum alpha-fetoprotein levels have been used as an important tumor marker for hepatoblastoma, hepatocellular carcinoma, and germ cell tumors. It is rarely elevated in hepatic hemangi...

journal_title：Pediatric hematology and oncology

authors： Sari N,Yalçin B,Akyüz C,Haliloglu M,Büyükpamukçu M

更新日期：2006-12-01 00:00:00

abstract：:Three cases of vitamin B12 deficiency that occurred during infancy are presented. These cases appeared to be the result of pre-existing maternal deficiency. All three infants demonstrated evidence of neurodevelopmental delay at presentation, and one had sustained loss of milestones and developed involuntary motor move...

journal_title：Pediatric hematology and oncology

authors： Doyle JJ,Langevin AM,Zipursky A

更新日期：1989-01-01 00:00:00

abstract：:We investigated bone marrow (BM) recovery of hematopoietic stem cells (HSC) and hematopoietic microenvironment after chemotherapy in childhood acute lymphoblastic leukemia (ALL). Twenty-nine de novo childhood ALL patients were enrolled and BM biopsy sections at diagnosis (BM0), after induction (BM1), consolidation (BM...

journal_title：Pediatric hematology and oncology

authors： Park SH,Lee MJ,Park CJ,Jang S,Seo EJ,Im HJ,Seo JJ

更新日期：2019-05-01 00:00:00

abstract：INTRODUCTION:Chronic liver disease causes a disruption of procoagulant and anticoagulant factors, resulting in a fragile state, prone to increased rates of both bleeding and thrombosis. Currently, there is limited literature describing the changes observed in pediatric liver disease and extrahepatic portal vein obstruc...

journal_title：Pediatric hematology and oncology

authors： Beattie W,Magnusson M,Hardikar W,Monagle P,Ignjatovic V

更新日期：2017-03-01 00:00:00

abstract：:Factor XIII deficiency is a very rare bleeding disorder. We report here on the clinical outcome of a young child with intracranial bleeding due to factor XIII deficiency. Clinicians should bear in mind that severe factor XIII deficiency is associated with a significant risk of unexpected intracranial hemorrhage (ICH)....

journal_title：Pediatric hematology and oncology

authors： Bay A,Sirikci A,Dogan A,Leblebisatan G,Yilmaz F

更新日期：2013-11-01 00:00:00

abstract：:Focal nodular hyperplasia (FNH) of the liver is rare in children, and it is usually diagnosed through a biopsy of the liver or hepatectomy. The authors report a case of a 10-year-old girl with multiple focal nodular hyperplasia lesions of the liver after the completion of tumor therapy for advanced neuroblastoma, and ...

journal_title：Pediatric hematology and oncology

authors： Sugito K,Kusafuka T,Kawashima H,Uekusa S,Furuya T,Ohashi K,Inoue M,Ikeda T,Koshinaga T,Maebayashi T

更新日期：2010-04-01 00:00:00

abstract：:It is well known in the literature that cancer creates educationally related barriers for all children, which may or may not contribute to clinically relevant school problems. The goal of this study was to obtain a base rate for the characteristic pattern of school functioning for children with leukemia, so that the c...

journal_title：Pediatric hematology and oncology

authors： Adamoli L,Deasy-Spinetta P,Corbetta A,Jankovic M,Lia R,Locati A,Fraschini D,Masera G,Spinetta JJ

更新日期：1997-03-01 00:00:00

abstract：:The majority of the anemias during childhood are hypochromic and microcytic. The aim of the present study was to determine the status of α-thalassemia mutations and its association with other etiologies, such as iron deficiency anemia (IDA) and β-thalassemia trait, that are frequently seen hypochromic microcytic anemi...

journal_title：Pediatric hematology and oncology

authors： Gulen H,Hanimeli O,Karaca O,Taneli F

更新日期：2012-04-01 00:00:00

abstract：:In recent years erythropoietic agents have become important tools in the management of anemia in cancer patients, improving hemoglobin (Hb) concentrations, reducing the need for transfusion, and enhancing quality of life. In this prospective and historically controlled study, the effects of epoetin beta on Hb concentr...

journal_title：Pediatric hematology and oncology

authors： Corapcioglu F,Aksu G,Basar EZ,Demirel A,Oncel S,Mutlu A

更新日期：2008-09-01 00:00:00

abstract：:To investigate the possible clinical application of the hypothesis that insufficient induction of 3,4-dihydroxyphenylalanine decarboxylase (DDC) causes accumulation and secretion of 3,4-dihydroxyphenylalanine (DOPA) in unfavorable neuroblastomas, we measured plasma DOPA in 28 neuroblastoma patients. Abnormally high le...

journal_title：Pediatric hematology and oncology

authors： Ikeda H,Suzuki N,Takahashi A,Kuroiwa M,Matsuyama S

更新日期：1996-01-01 00:00:00

abstract：:Osteoporosis is common in patients with thalassemia major. A 16-year-old patient with thalassemia major was referred for evaluation of osteoporosis. The results of dual-energy X-ray absorptiometry in a patient with thalassemia major are presented. The patient underwent measurements of the spine in both AP and lateral ...

journal_title：Pediatric hematology and oncology

authors： Yildiz M,Canatan D

更新日期：2005-12-01 00:00:00

abstract：:The aim of this study was to investigate the impact of therapy on long-term gonadal function of young people cured of childhood lymphomas and to assess whether a prepubertal state during the treatment protects the gonads from chemotherapy and/or radiotherapy late effects. Clinical evaluation, semen analysis, and endoc...

journal_title：Pediatric hematology and oncology

authors： Ben Arush MW,Solt I,Lightman A,Linn S,Kuten A

更新日期：2000-04-01 00:00:00

abstract：UNLABELLED:In settings of limited health resources, using leukocyte-filtered blood is limited to patients with leukocyte-mediated complications. The aim of this study was to determine the patterns of lung dysfunction among patients with β-thalassemia major (BTM) after the application of the leukostop filter during tran...

journal_title：Pediatric hematology and oncology

authors： Hamed Ael S,Ragab IA,Kamel TB,Abd-El-Gawad AO

更新日期：2013-11-01 00:00:00