Oral and dental findings in Fanconi's anemia.

Abstract:

:Fanconi's anemia is an autosomal recessive disorder characterized by progressive pancytopenia and congenital malformation of the skeleton. This study investigated the oral health status of 15 children with Fanconi's anemia, including oral lesions, gingival and periodontal status, and dental abnormalities. All children in the group were found to have a tendency to develop tooth decay and were in need of dental treatment. Two had aggressive periodontitis. In one patient supernumerary teeth were found, while in another teeth were congenitally missing. The increased tendency toward periodontal disease in patients with Fanconi's anemia may be due not only to the anemia, leukopenia, and defective detoxification of oxygen radicals that are characteristic of the disease itself, but also to medications applied during intense immunosuppressive treatment, such as prednisolone.

journal_name

Pediatr Hematol Oncol

authors

Açikgöz A,Ozden FO,Fisgin T,Açikgöz G,Duru F,Yarali N,Albayrak D

doi

10.1080/08880010591002413

subject

Has Abstract

pub_date

2005-09-01 00:00:00

pages

531-9

issue

6

eissn

0888-0018

issn

1521-0669

pii

J45840087717R380

journal_volume

22

pub_type

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