Bone marrow recovery of hematopoietic stem cells and microenvironment after chemotherapy in childhood acute lymphoblastic leukemia: consecutive observations according to chemotherapy schedule.

abstract：UNLABELLED:In settings of limited health resources, using leukocyte-filtered blood is limited to patients with leukocyte-mediated complications. The aim of this study was to determine the patterns of lung dysfunction among patients with β-thalassemia major (BTM) after the application of the leukostop filter during tran...

journal_title：Pediatric hematology and oncology

authors： Hamed Ael S,Ragab IA,Kamel TB,Abd-El-Gawad AO

更新日期：2013-11-01 00:00:00

abstract：:All pediatric osteosarcomas treated in our hospital between 1985 and 1995 were reviewed. There were 26 patients, 15 males and 11 females, aged 20 or less at diagnosis. All had limb primaries. Nineteen patients had localized disease and seven presented with metastases. Intensive multiagent chemotherapy was given both p...

journal_title：Pediatric hematology and oncology

authors： Kwong DL,Ha SY,Chau KY,Choi PH,Chan GC,Kwong PW,Lau YL

更新日期：1998-05-01 00:00:00

abstract：:Fever and neutropenia (FN) is a common precipitant for hospitalization among children with cancer, but hospital utilization trends are not well described. This study describes national trends for hospital discharges for FN among children with cancer for the year 2012, compared with the authors' previous analysis from ...

journal_title：Pediatric hematology and oncology

authors： Mueller EL,Croop J,Carroll AE

更新日期：2016-02-01 00:00:00

abstract：:Autologous blood-derived stem cells were used for stem-cell rescue in a 5-year-old boy with chemotherapy-resistant B-Non-Hodgkin's lymphoma (B-NHL) involving bone marrow. The high dose chemoradiotherapy was carried out 5 months after initial diagnosis during partial remission. The preparative regimen consisted of 12 G...

journal_title：Pediatric hematology and oncology

authors： Emminger W,Emminger-Schmidmeier W,Ambros P,Gadner H,Höcker P,Radaszkiewicz T,Hinterberger W

更新日期：1990-01-01 00:00:00

abstract：:Factor XIII deficiency is a very rare bleeding disorder. We report here on the clinical outcome of a young child with intracranial bleeding due to factor XIII deficiency. Clinicians should bear in mind that severe factor XIII deficiency is associated with a significant risk of unexpected intracranial hemorrhage (ICH)....

journal_title：Pediatric hematology and oncology

authors： Bay A,Sirikci A,Dogan A,Leblebisatan G,Yilmaz F

更新日期：2013-11-01 00:00:00

abstract：:Spontaneous remission/regression of cancer is defined as partial or complete disappearance of malignant disease temporarily or permanently in the absence of medical treatment. This event is named as spontaneous regression for solid tumors and spontaneous remission for leukemia. The authors report the case of a girl ag...

journal_title：Pediatric hematology and oncology

authors： Yoruk A,Erguven M,Celiker E,Aki H,Timur C,Yuksel E,Ozkan H

更新日期：2008-04-01 00:00:00

abstract：:Factor X (FX) is the component of both extrinsic and intrinsic coagulation cascade and is the first enzyme of the common pathway which results in thrombus. Congenital FX deficiency (FXD) is an extremely rare coagulation defect. In this study, we aimed to investigate the clinical and laboratory data of the patients dia...

journal_title：Pediatric hematology and oncology

authors： Karabel M,Söker M,Yıldırım AT,Oymak Y,Kelekçi S,Karabel D

更新日期：2013-11-01 00:00:00

abstract：:The third International Conference on Immunotherapy in Pediatric Oncology was held in Frankfurt/Main, Germany, October 1-2, 2012. Major topics of the conference included (i) cellular therapies using antigen-specific and gene-modified T cells for targeting leukemia and pediatric solid tumors; (ii) overcoming hurdles an...

journal_title：Pediatric hematology and oncology

authors： Brehm C,Huenecke S,Pfirrmann V,Rossig C,Mackall CL,Bollard CM,Gottschalk S,Schlegel PG,Klingebiel T,Bader P

更新日期：2013-08-01 00:00:00

abstract：:We present the case of a female newborn with life-threatening bleeding of a ruptured infantile fibrosarcoma (IFS) and consecutive multiorgan dysfunction syndrome shortly after birth. After stabilization, the tumor could be treated without amputation due to surgery, laser therapy, and chemotherapy. The patient is free ...

journal_title：Pediatric hematology and oncology

authors： Kerl K,Nowacki M,Leuschner I,Masjosthusmann K,Frühwald MC

更新日期：2012-09-01 00:00:00

abstract：:Neutropenic enterocolitis is an acute, life-threatening inflammation of the small and large bowel, often seen in children with malignancies during periods of prolonged or severe neutropenia. During the period 1990-1995, 180 children were treated at the authors' center for acute lymphoblastic leukemia using a standard ...

journal_title：Pediatric hematology and oncology

authors： Jain Y,Arya LS,Kataria R

更新日期：2000-01-01 00:00:00

abstract：:The authors aimed to investigate the efficacy of epoetin-alpha on hemoglobin levels and red cell transfusion requirement in children with both hematologic malignancy (HM, n = 27) and solid tumors (ST, n = 14). Epoetin-alpha was given (150 U/kg or 250 U/kg, thrice weekly) for 12 weeks. Epoetin alpha significantly incre...

journal_title：Pediatric hematology and oncology

authors： Yilmaz D,Cetingül N,Kantar M,Oniz H,Kansoy S,Kavakli K

更新日期：2004-01-01 00:00:00

abstract：:Increased susceptibility to infection is reported in patients with beta-thalassemia major due to toxic effect of iron on neutrophil functions and reticuloendothelial system dysfunction. This study investigated the association between the neutrophil apoptosis and frequency of infection episodes, desferrioxamine treatme...

journal_title：Pediatric hematology and oncology

authors： Oren H,Sahin B,Irken G,Ateş H,Duman M,Yilmaz S,Türker M,Atabay B,Yaprak I

更新日期：2003-04-01 00:00:00

abstract：:Blast cell chromosome abnormalities at presentation in childhood acute lymphoblastic leukemia (ALL) are common, and different patterns are known to be related to outcome. In contrast, the frequency and importance of further changes at the time of relapse remain unclear. Blast cell karyotype evolution was therefore stu...

journal_title：Pediatric hematology and oncology

authors： Vora AJ,Potter AM,Anderson LM,Lilleyman JS

更新日期：1994-07-01 00:00:00

abstract：:Down syndrome (DS) is an important risk factor associated with acute leukemia (AL). The presence of polymorphisms that reduce 5,10-methylenetetrahydrofolate reductase (MTHFR) activity has been linked to the multifactorial leukemogenic process. The authors have conducted a study to test whether 677C-->T and/or 1298A-->...

journal_title：Pediatric hematology and oncology

authors： Amorim MR,Zanrosso CW,Magalhães IQ,Pereira SC,Figueiredo A,Emerenciano M,Pinheiro VR,d'Andréa ML,Orioli IM,Koifman S,Pombo-de-Oliveira MS

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:To describe clinical and CT features of L-asparaginase-associated pancreatitis (L-AP) and to correlate CT grades with clinical parameters. METHODS:A total of 16 children (M:F = 9:7; mean age, 8.1 years) who developed L-AP after L-asparaginase (L-asp) treatment and underwent abdominal CT scan were included. We ...

journal_title：Pediatric hematology and oncology

authors： Oh HJ,Im SA,Lee JW,Chung NG,Cho B

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:We aimed to examine the association between vitamin D deficiency and anemia in a nationally representative sample of Korean children and adolescents. METHODS:Cross-sectional data on 2526 children and adolescents aged 10-20 years from the Korea National Health and Nutrition Examination Survey-V (2010-2012) w...

journal_title：Pediatric hematology and oncology

authors： Lee JA,Hwang JS,Hwang IT,Kim DH,Seo JH,Lim JS

更新日期：2015-03-01 00:00:00

abstract：:In this study, 82 Turkish children with Hodgkin's disease (HD) between 1 and 14 years of age and diagnosed over a 10-year period were evaluated retrospectively. More than half of the patients (54%) presented with advanced stages of HD. Mixed cellularity (MC) was the most frequent (56.1%) histopathologic type, which wa...

journal_title：Pediatric hematology and oncology

authors： Ertem U,Duru F,Dağdemir A,Taçyildiz N,Pamir A,Akçayöz A,Uluoğlu O,Teziç T

更新日期：1997-07-01 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) is a rare and fatal hematological syndrome that causes a disturbance of the immune system. Overall mortality of HLH is greater than 50% and the majority of patients who die do so within the first 8 weeks of chemotherapy treatment. To find clinical parameters relating to high-ri...

journal_title：Pediatric hematology and oncology

authors： Dao AT,Luong VT,Nguyen TT,Huynh QT,Phan TT,Lam MT,Ngoma AM,Koriyama C

更新日期：2014-04-01 00:00:00

abstract：:The reported long-term outcome of endemic Burkitt lymphoma (eBL) patients who present with paraplegia is largely unknown. Records of BL patients treated with comparable short-interval cyclophosphamide chemotherapy schedules between 2004 and 2014 at three Baptist mission hospitals in Cameroon were reviewed. Survivors w...

journal_title：Pediatric hematology and oncology

authors： Hesseling PB,Mbah G,Kouya F,Kimbi C,Nfor P,Kaah J,Kuruvilla R,Best A,Wharin P

更新日期：2015-01-01 00:00:00

abstract：:We have read, with great interest, the recent article by Lee. In this excellent study, the authors investigated the association between vitamin D deficiency and anemia in a nationally representative sample of Korean children and adolescents. They concluded that vitamin D deficiency is associated with increased risk of...

journal_title：Pediatric hematology and oncology

authors： Kartal Ö,Kartal AT

更新日期：2015-01-01 00:00:00

abstract：:Methotrexate (MTX) is an antimetabolite with a major role in the treatment of acute lymphoblastic leukaemia (ALL). The authors report the management of a 9-year-old boy who developed an anaphylactoid reaction to high-dose MTX infusion, after a first challenge with intrathecal administration, during induction therapy f...

journal_title：Pediatric hematology and oncology

authors： Caldeira T,Costa V,Silva I,Oliva T,Norton L

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The Wiskott-Aldrich syndrome (WAS) is X-linked recessive disorder associated with microplatelet thrombocytopenia, eczema, infections, and an increased risk of autoimmunity and lymphoid neoplasia. The originally described features of WAS include susceptibility to infections, microthrombocytopenia, and eczema....

journal_title：Pediatric hematology and oncology

authors： Kamuran K,Çetin M,Geylan H,Karaman S,Demir N,Yurekturk E,Yavuz İ,Yavuz G,Tuncer O

更新日期：2017-08-01 00:00:00

abstract：:Four children with beta-thalassemia intermedia ages 7 to 11 years developed a clinical picture characterized by headache, hypertension, convulsion, and cerebral hemorrhage after blood transfusion. Successive transfusions did not result in a similar picture. Factors responsible for this syndrome are discussed. ...

journal_title：Pediatric hematology and oncology

authors： Gürgey A,Kalayci O,Gümrük F,Cetin M,Altay C

更新日期：1994-09-01 00:00:00

abstract：:Signaling between leukemia cells and nonhematopoietic cells in the bone marrow microenvironment contributes to leukemia cell growth and survival. This complicated extrinsic mechanism of chemotherapy resistance relies on a number of pathways and factors, some of which have yet to be determined. Research on cell-cell cr...

journal_title：Pediatric hematology and oncology

authors： Sison EAR,Kurre P,Kim YM

更新日期：2017-01-01 00:00:00

abstract：:One of the causes of the childhood anemia is gastrointestinal system bleeding, which rarely results from parasites. The authors report on a 3-year-old boy with severe anemia and a history of hematemesis. While they were investigating the cause of the anemia and the hematemesis, a leech showing itself in the nasal pass...

journal_title：Pediatric hematology and oncology

authors： Demirören K,Calişkan U

更新日期：2003-10-01 00:00:00

abstract：:Li-Fraumeni syndrome (LFS) is one of the familial cancers characterized by different tumors and hereditary TP53 mutations. The adrenocortical carcinoma (ACC) association with acute leukemia is unusual in childhood, even in LFS. The authors here present a family with pR337P mutation in TP53 gene who had a child with ac...

journal_title：Pediatric hematology and oncology

authors： Karakas Z,Tugcu D,Unuvar A,Atay D,Akcay A,Gedik H,Kayserili H,Dogan O,Anak S,Devecioglu O

更新日期：2010-05-01 00:00:00

abstract：:Neuroblastoma presenting with obstructive jaundice is a rare event. Management of this condition includes surgery, chemotherapy, radiotherapy, temporary cholecystostomy tube, endoscopic retrograde cholangiopancreatography (ERCP), and internal biliary drainage (IBD). We herein describe our experience with one infant af...

journal_title：Pediatric hematology and oncology

authors： Saettini F,Agazzi R,Giraldi E,Foglia C,Cavalleri L,Morali L,Fasolini G,Spotti A,Provenzi M

更新日期：2015-04-01 00:00:00

abstract：:Growth was studied longitudinally in 19 children who were long-term survivors after acute lymphoblastic leukemia (ALL). Of the children, 13 were girls; 6 were boys. They had all undergone a 3-year cytostatic treatment period which included vincristine, adriamycin, asparaginase, methotrexate, purinethol, and prednisone...

journal_title：Pediatric hematology and oncology

authors： Sempoux P,Moëll C,Cornu G,Malvaux P,Maes M

更新日期：1992-07-01 00:00:00

abstract：:The acquired form of pure red cell aplasia (PRCA) presents either as an acute self-limited disease, predominantly seen in children, or as a chronic illness more frequently seen in adults with rare spontaneous remissions. A 14-year-old boy presented with pallor, without hepatosplenomegaly, jaundice, lymphadenopathy, pe...

journal_title：Pediatric hematology and oncology

authors： Khalil A,Elhasid R,Ben Barak A,Ben Arush MW

更新日期：2010-10-01 00:00:00

abstract：:Adrenocortical carcinoma (ACC) is a rare, aggressive endocrine neoplasm. Complete surgical resection is the single most important treatment. Most available information has been learned from experience with its more frequent adult counterpart. In this study, we assessed the features and survival outcome of patients wit...

journal_title：Pediatric hematology and oncology

authors： Zekri W,Hammad M,Rashed WM,Ahmed G,Elshafie M,Adly MH,Elborai Y,Abdalla B,Taha H,Elkinaae N,Refaat A,Younis A,Alfaar AS

更新日期：2020-04-01 00:00:00