Anaphylactoid reaction to high-dose methotrexate and re-administration after a successful desensitization.

abstract：:Ataxia-telangiectasia is an autosomal recessive disease characterized by progressive cerebellar ataxia, oculocutaneous telangiectasia, immunodeficiency, high incidence of cancer, and increased sensitivity to ionizing radiation. The authors report a case of dysgerminoma in a child with high alpha-fetoprotein, CA125 and...

journal_title：Pediatric hematology and oncology

authors： Koksal Y,Caliskan U,Ucar C,Yurtcu M,Artac H,Ilerisoy-Yakut Z,Reisli I

更新日期：2007-09-01 00:00:00

abstract：:Although survival rates in childhood cancer have distinctly improved, pediatric cancer patients often experience various disease- and treatment-related side effects with long-term consequences. Despite current studies investigating inactivity and limitations in physical functioning and quality of life in pediatric can...

journal_title：Pediatric hematology and oncology

authors： Beulertz J,Bloch W,Prokop A,Baumann FT

更新日期：2013-05-01 00:00:00

abstract：:Malignant rhabdoid tumors (MRT) of soft tissues are aggressive tumors, which can be detected in almost any part of the body. MRT are rare, and very few cases have been reported in the literature. Prognosis of these tumors is extremely poor despite intensive therapy. Some risk factors such as young age or disseminated ...

journal_title：Pediatric hematology and oncology

authors： Hernández-Marqués C,Lassaletta A,Cormenzana M,García-Esparza E,Madero-López L

更新日期：2015-04-01 00:00:00

abstract：:Growth was studied longitudinally in 19 children who were long-term survivors after acute lymphoblastic leukemia (ALL). Of the children, 13 were girls; 6 were boys. They had all undergone a 3-year cytostatic treatment period which included vincristine, adriamycin, asparaginase, methotrexate, purinethol, and prednisone...

journal_title：Pediatric hematology and oncology

authors： Sempoux P,Moëll C,Cornu G,Malvaux P,Maes M

更新日期：1992-07-01 00:00:00

abstract：:Renal and metabolic complications of tumor lysis syndrome (TLS) were recognized frequently in the 1960s and 1970s. Strategies were designed to prevent TLS. We conducted a retrospective chart review study to identify the current TLS risk in children with acute leukemia. Children were considered to have "laboratory tumo...

journal_title：Pediatric hematology and oncology

authors： Kedar A,Grow W,Neiberger RE

更新日期：1995-03-01 00:00:00

abstract：:The authors describe the relation between clamping time and blood volume collected, and two enrichment systems of CD34+ stem cells from umbilical cord blood, to determine an excellent recovery with high proliferate ability and bone marrow reconstitution. After an obstetrician-based cord blood collection, the purificat...

journal_title：Pediatric hematology and oncology

authors： Pafumi C,Bosco P,Cavallaro A,Farina M,Leonardi I,Pernicone G,Bandiera S,Russo A,Giardina P,Chiarenza M,Calogero AE

更新日期：2002-06-01 00:00:00

abstract：:Unexplained menorrhagia and hematuria occurred in a 13-year-old female with a mild inherited platelet disorder who had never experienced prior bleeding as a result of this disorder. An intensive search revealed that this patient was receiving coumadin that was given by the mother. In addition, the mother drew large vo...

journal_title：Pediatric hematology and oncology

authors： Souid AK,Korins K,Keith D,Dubansky S,Sadowitz PD

更新日期：1993-07-01 00:00:00

abstract：:Endocrine system dysfunctions are the significant complications of excessive iron overload in beta thalassemia patients. The aim of this study was to evaluate the long-term effect of chelation with deferasirox on endocrine complications. The study group consisted of children with beta thalassemia who had been evaluate...

journal_title：Pediatric hematology and oncology

authors： Bilgin BK,Yozgat AK,Isik P,Çulha V,Kacar D,Kara A,Ozbek NY,Yarali N

更新日期：2020-09-01 00:00:00

abstract：:Down syndrome (DS) is an important risk factor associated with acute leukemia (AL). The presence of polymorphisms that reduce 5,10-methylenetetrahydrofolate reductase (MTHFR) activity has been linked to the multifactorial leukemogenic process. The authors have conducted a study to test whether 677C-->T and/or 1298A-->...

journal_title：Pediatric hematology and oncology

authors： Amorim MR,Zanrosso CW,Magalhães IQ,Pereira SC,Figueiredo A,Emerenciano M,Pinheiro VR,d'Andréa ML,Orioli IM,Koifman S,Pombo-de-Oliveira MS

更新日期：2008-12-01 00:00:00

abstract：:Thalassemic children are at a high risk of graft rejection in cord blood transplantation. To investigate this possible mechanism, the authors evaluated the effect of panel reactive antibody on the growth of CD34(+) cells in vitro. On semisolid medium, CD34(+) cells derived from cord blood were incubated with thalassem...

journal_title：Pediatric hematology and oncology

authors： Fang JP,Xu LH,Yang XG,Wu YF,Weng WJ,Xu HG

更新日期：2009-07-01 00:00:00

abstract：:Invasive aspergillosis is a fungal infection that is being observed increasingly in immunocompromised patients due to the use of more aggressive chemotherapeutic regimens. To our knowledge, no case of pneumothorax and pneumopericardium associated with invasive pulmonary aspergillosis has been reported to date. High-do...

journal_title：Pediatric hematology and oncology

authors： Merino JM,Díaz MA,Ramírez M,Ruano D,Madero L

更新日期：1995-03-01 00:00:00

abstract：:A case of a 4-year-old girl with pleuropulmonary blastoma is reported. Surgical resection of the tumor was performed and histologic examination revealed pleuropulmonary blastoma with rhabdomyosarcomatous differentiation. Postoperative chemotherapy was administered and 3 weeks after initiation of treatment protocol a s...

journal_title：Pediatric hematology and oncology

authors： Perdikogianni C,Stiakaki E,Danilatou V,Delides G,Kalmanti M

更新日期：2001-06-01 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) embraces the frequently indistinguishable conditions of familial hemophagocytic lymphohistiocytosis (FHL) and virus-associated hemophagocytic syndrome (VAHS). Without therapy FHL is invariably fatal, but successful therapy, including chemotherapy and immunotherapy followed by b...

journal_title：Pediatric hematology and oncology

authors： Al-Lamki Z,Wali YA,Pathare A,Ericson KG,Henter JI

更新日期：2003-12-01 00:00:00

abstract：:Maternal education might be an important factor for the neuroblastoma risk in children, but it was conflicting. This meta-analysis was performed to evaluate the relationship between maternal education and neuroblastoma susceptibility and to explore whether maternal education was an important indicator to be associated...

journal_title：Pediatric hematology and oncology

authors： Wang P,Liao N,Liao XH,Liang B,Huang CX,Li W

更新日期：2013-02-01 00:00:00

abstract：:The use of G-CSF after myelotoxic chemotherapy accelerates neutrophil recovery reducing the risk of febrile neutropenia. Current guidelines recommend initiating G-CSF 24 hours after myelotoxic chemotherapy. However, the optimal timing of post-chemotherapy G-CSF administration has not been elucidated. Our previous work...

journal_title：Pediatric hematology and oncology

authors： Yankelevich M,Hoogstra DJ,Abrams J,Chu R,Bhambhani K,Taub JW

更新日期：2020-11-01 00:00:00

abstract：:High doses of intravenous deferoxamine via central venous line (CVL) has recently been shown to improve survival in patients with noncompliant thalassemia major (TM). The aim of this retrospective study was to evaluate the extent of CVL-related thrombosis and to determine the presence of prothrombotic factors in child...

journal_title：Pediatric hematology and oncology

authors： Finkelstein Y,Yaniv I,Berant M,Zilber R,Garty BZ,Epstein O,Lahav J,Tamary H

更新日期：2004-07-01 00:00:00

abstract：:Neuroblastoma is the most common solid tumor in childhood and is the most frequent neural crest tumor (NCT). More than 90% of the patients excrete high levels of vanilmandelic acid (VMA) and homovanillic acid (HVA) in the urine. Original biochemical methods for measuring these two metabolites of catecholamines employe...

journal_title：Pediatric hematology and oncology

authors： Gregianin LJ,McGill AC,Pinheiro CM,Brunetto AL

更新日期：1997-05-01 00:00:00

abstract：:Hyperleukocytosis in patients with leukemia is associated with early mortality, especially due to the pulmonary and neurological complications of leukostasis. The prompt use of leukapheresis may improve patients' survival in the initial treatment period. The medical records of all previously untreated acute leukemia p...

journal_title：Pediatric hematology and oncology

authors： Yilmaz D,Karapinar B,Karadaş N,Duyu M,Yazici P,Ay Y,Balkan C,Aydinok Y,Kavakli K

更新日期：2014-05-01 00:00:00

abstract：AIM:To standardize diagnosis and treatment of childhood Wilms tumor (WT) in Turkey. METHODS AND PATIENTS:Between 1998 and 2006, WT patients were registered from 19 centers. Patients <16 years with unilateral WT whose treatment started in first postoperative 3 weeks were included. Treatments were stage I favorable (FH)...

journal_title：Pediatric hematology and oncology

authors： Akyüz C,Yalçin B,Yildiz I,Hazar V,Yörük A,Tokuç G,Akici F,Büyükpamukçu N,Kale G,Atahan L,Büyükünal C,Dervişoğlu S,Atkovar GA,Melikoğlu M,Karpuzoğlu G,Olgun N,Ayan I,Oğuz A,Yariş N,Dağdemir A,Darendeliler E,Sande

更新日期：2010-04-01 00:00:00

abstract：:Modern treatment protocols lead to complete remission in a high proportion of patients with childhood acute lymphoblastic leukemia (ALL). However, a large number of them show a relapse of the disease. Treatment failure in these patients is mainly attributable to de novo or acquired resistance to a wide variety of cyto...

journal_title：Pediatric hematology and oncology

authors： Kourti M,Vavatsi N,Gombakis N,Tzimagiorgis G,Sidi V,Koliouskas D,Athanassiadou F

更新日期：2006-09-01 00:00:00

abstract：:In an autopsy series of children with cancer, histopathologic myocardial changes caused by anthracyclines (A) were evaluated. The series comprised three groups: group A, 9 patients given A whose myocardial function had been evaluated before death; group B, 10 patients given A, but no lifetime echocardiographic evaluat...

journal_title：Pediatric hematology and oncology

authors： Pihkala J,Sariola H,Saarinen UM

更新日期：1994-05-01 00:00:00

abstract：:Primary bone marrow lymphoma (PBML) is hard to diagnose in children, due to the difficult identification of malignant cells in bone marrow. The first case, a 5-year-old boy, showed knee swelling with an intermittent fever. The second case, a 12-year-old girl, showed fever of unknown origin without lymphadenopathy or h...

journal_title：Pediatric hematology and oncology

authors： Moritani K,Nakano N,Yonezawa S,Ochi F,Tauchi H,Eguchi-Ishimae M,Eguchi M,Ishii E,Nagai K

更新日期：2018-03-01 00:00:00

abstract：:Between 1973 and 1991, 10 patients with locally advanced [stages III and IV] nasopharyngeal carcinoma were treated at the Northern Israel Oncology Center. All patients were treated with wide-field irradiation to the primary tumor, including the base of skull, neck, and supraclavicular region. After 1984, 6 patients al...

journal_title：Pediatric hematology and oncology

authors： Arush MW,Stein ME,Rosenblatt E,Lavie R,Kuten A

更新日期：1995-05-01 00:00:00

abstract：:A cooperative Italian study group on acute idiopathic thrombocytopenic purpura (AITP) has been designed to evaluate efficacy and safety of no treatment at the onset of the disease and sequential treatment with immunoglobulin and high dose steroid. One hundred thirty-eight patients with AITP entered in the trial. Eleve...

journal_title：Pediatric hematology and oncology

authors： Mori PG,Lanza T,Mancuso G,De Mattia D,Catera P,Miano C,Del Principe D,Cottafava F

更新日期：1988-01-01 00:00:00

abstract：:A 9-year-old girl presented at the Pediatric Emergency Department with an acute onset of gastrointestinal symptoms due to hypercalcemia. Despite the absence of circulating blast, bone marrow biopsy was diagnostic of acute lymphoblastic leukemia. The hypercalcemia was initially treated with intravenous hydration and fu...

journal_title：Pediatric hematology and oncology

authors： Buonuomo PS,Ruggiero A,Piastra M,Riccardi R,Polidori G,Chiaretti A

更新日期：2004-09-01 00:00:00

abstract：:Endothelial protein C receptor (EPCR) is primarily localized on the endothelial cells of large blood vessels and is very low or absent in the microvascular endothelium of most tissues. EPCR augments the thrombin/thrombomodulin-dependent activation of protein C by 5- to 20-fold. EPCR appears to be physiologically signi...

journal_title：Pediatric hematology and oncology

authors： Kendirli T,Ciftçi E,Ince E,Yurdakul E,Kansu A,Akar N

更新日期：2007-04-01 00:00:00

abstract：:Fever and neutropenia (FN) is a common precipitant for hospitalization among children with cancer, but hospital utilization trends are not well described. This study describes national trends for hospital discharges for FN among children with cancer for the year 2012, compared with the authors' previous analysis from ...

journal_title：Pediatric hematology and oncology

authors： Mueller EL,Croop J,Carroll AE

更新日期：2016-02-01 00:00:00

abstract：:Plexiform neurofibroma is a relatively common but potentially devastating manifestation of neurofibromatosis type 1 (NF 1). A substantial number of plexiform neurofibroma causes morbidity. Various treatment modalities are considered to decrease pain. In this paper a case with plexiform neurofibroma causing severe pain...

journal_title：Pediatric hematology and oncology

authors： Citak EC,Oguz A,Karadeniz C,Okur A,Memis L,Boyunaga O

更新日期：2008-09-01 00:00:00

abstract：:A patient with well-differentiated monoblastic leukemia (ANLL FAB-M5b) is described in whom acute leukemia was diagnosed 25 months after having completed postoperative adjuvant chemotherapy for osteogenic sarcoma of the femur. All analyzed metaphases showed 48xy, dup 1(q12), +3, +9. ...

journal_title：Pediatric hematology and oncology

authors： Orazi A,Sozzi G,Delia D,Morandi F,Rottoli L,Cattoretti G

更新日期：1988-01-01 00:00:00

abstract：:Outcomes in pediatric B-Non-Hodgkin Lymphoma (B NHL) have improved with intensive chemotherapy protocols, with long-term survival now over 80%. However, long-term adverse effects of therapy and poor outcomes for patients who relapse remain challenges. In this study, we aimed to evaluate the potential risks and benefit...

journal_title：Pediatric hematology and oncology

authors： Eissa HM,Allen CE,Kamdar K,Simko S,Goradia P,Dreyer Z,Steuber P,McClain KL,Guillerman RP,Bollard CM

更新日期：2014-04-01 00:00:00