Central venous line thrombosis in children and young adults with thalassemia major.

abstract：:Although survival rates in childhood cancer have distinctly improved, pediatric cancer patients often experience various disease- and treatment-related side effects with long-term consequences. Despite current studies investigating inactivity and limitations in physical functioning and quality of life in pediatric can...

journal_title：Pediatric hematology and oncology

authors： Beulertz J,Bloch W,Prokop A,Baumann FT

更新日期：2013-05-01 00:00:00

abstract：:Eighty-six patients with Ewing's sarcoma were analyzed as to the role of radiation therapy. Fifty-eight patients (P group) had removal of the involved part of the bone after preoperative chemotherapy, and 28 (NP group) had local treatment either at the same time or before chemotherapy. Thirty-six of 58 P-group patient...

journal_title：Pediatric hematology and oncology

authors： Jereb B,Ong RL,Mohan M,Caparros B,Exelby P

更新日期：1986-01-01 00:00:00

abstract：:Hyperleukocytosis in patients with leukemia is associated with early mortality, especially due to the pulmonary and neurological complications of leukostasis. The prompt use of leukapheresis may improve patients' survival in the initial treatment period. The medical records of all previously untreated acute leukemia p...

journal_title：Pediatric hematology and oncology

authors： Yilmaz D,Karapinar B,Karadaş N,Duyu M,Yazici P,Ay Y,Balkan C,Aydinok Y,Kavakli K

更新日期：2014-05-01 00:00:00

abstract：:Medulloblastoma (MB) is a cancer of the cerebellum and the most common primary pediatric malignancy of the central nervous system. Classified as a primitive neural ectoderm tumor; it is thought to arise from granule cell precursors in the cerebellum. The standard of care consists of surgery, chemotherapy and age-depen...

journal_title：Pediatric hematology and oncology

authors： Byrd T,Grossman RG,Ahmed N

更新日期：2012-09-01 00:00:00

abstract：:The clinical usefulness of the measurement of red cell zinc protoporphyrin (ZPP), an indicator of iron-deficient erythropoiesis, was assessed in a group of UK children undergoing investigation for red cell microcytosis. Of 213 children studied, 136 had increased ZPP values. Of these, 86 also had reduced iron stores as...

journal_title：Pediatric hematology and oncology

authors： Hinchliffe RF,Lilleyman JS,Steel GJ,Bellamy GJ

更新日期：1995-09-01 00:00:00

abstract：:Nesiritide is a recombinant formulation of B-type natriuretic peptide used most commonly in the treatment of adults with decompensated congestive heart failure. The physiologic effects of BNP include natriuresis, diuresis, and smooth muscle relaxation. These physiologic effects result in its beneficial therapeutic eff...

journal_title：Pediatric hematology and oncology

authors： Wheeler AD,Tobias JD

更新日期：2005-06-01 00:00:00

abstract：:Two children are described who presented with fever and generalized seizures, days 50 and 200, respectively, after matched unrelated donor-bone marrow transplantation. Upon antiepileptic treatment the seizures vanished but somnolence and fever remained. Magnetic resonance imaging (MRI) of the brain was performed and r...

journal_title：Pediatric hematology and oncology

authors： Fischmeister G,Wiesbauer P,Holzmann HM,Peters C,Eibl M,Gadner H

更新日期：2000-07-01 00:00:00

abstract：:We investigated bone marrow (BM) recovery of hematopoietic stem cells (HSC) and hematopoietic microenvironment after chemotherapy in childhood acute lymphoblastic leukemia (ALL). Twenty-nine de novo childhood ALL patients were enrolled and BM biopsy sections at diagnosis (BM0), after induction (BM1), consolidation (BM...

journal_title：Pediatric hematology and oncology

authors： Park SH,Lee MJ,Park CJ,Jang S,Seo EJ,Im HJ,Seo JJ

更新日期：2019-05-01 00:00:00

abstract：:The Department of Oncology at Hospital Infantil de México Federico Gómez (HIMFG) was the first unit in our country, and one of the first in Latin America, to specialize in the management of children with cancer. The HIMFG is part of the National Institutes of Health of Mexico, and is a reference hospital with research...

journal_title：Pediatric hematology and oncology

authors： Medina-Sanson A,Martínez-Avalos A,Gallegos-Castorena S,Juárez-Villegas LE,González-Montalvo P,Perales-Arroyo A,Gallegos-González E,Ayometzi-Ouchi MT

更新日期：2002-09-01 00:00:00

abstract：:The aim of this study was to investigate the impact of therapy on long-term gonadal function of young people cured of childhood lymphomas and to assess whether a prepubertal state during the treatment protects the gonads from chemotherapy and/or radiotherapy late effects. Clinical evaluation, semen analysis, and endoc...

journal_title：Pediatric hematology and oncology

authors： Ben Arush MW,Solt I,Lightman A,Linn S,Kuten A

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:Recent guidelines recommend to assess emotional distress in pediatric oncology during treatment and in after care. One tool used to do this is the distress thermometer (DT), a simple tool which has almost exclusively been studied in its screening abilities. Given its increased used as a measure of distress p...

journal_title：Pediatric hematology and oncology

authors： Pépin AJ,Lippé S,Krajinovic M,Laverdière C,Michon B,Sinnett D,Sultan S

更新日期：2017-04-01 00:00:00

abstract：:Overall survival from cancer has greatly improved, although it still remains the second leading cause of mortality in the world. This result was achieved through the use of chemotherapy and radiotherapy, which are severely toxic to normal tissues. In the long-term follow-up of cancer patients, the development of secon...

journal_title：Pediatric hematology and oncology

authors： Varan A,Kebudi R

更新日期：2011-08-01 00:00:00

abstract：:A case of eosinophilic meningitis 2 months before the appearance of lymphoblasts in the cerebrospinal fluid is described in a child with acute lymphoblastic leukemia (ALL). The peripheral blood showed no simultaneous eosinophilia. The child was successfully treated for her CNS relapse, and complete remission was easil...

journal_title：Pediatric hematology and oncology

authors： Behrendt H,de Korte D,van Gennip AH,van Leeuwen EF

更新日期：1987-01-01 00:00:00

abstract：:Primary erythrocytosis diagnosed in a 10-month-old female and followed for 12 years is described. The erythrocytosis was associated with an abnormally elevated set point of erythropoietin production in which the sensitivity fluctuated independently, but corresponded to the alterations in the oxygen-carrying capacity o...

journal_title：Pediatric hematology and oncology

authors： Kalmantis T,Kalmanti M

更新日期：1991-07-01 00:00:00

abstract：:Modern treatment protocols lead to complete remission in a high proportion of patients with childhood acute lymphoblastic leukemia (ALL). However, a large number of them show a relapse of the disease. Treatment failure in these patients is mainly attributable to de novo or acquired resistance to a wide variety of cyto...

journal_title：Pediatric hematology and oncology

authors： Kourti M,Vavatsi N,Gombakis N,Tzimagiorgis G,Sidi V,Koliouskas D,Athanassiadou F

更新日期：2006-09-01 00:00:00

abstract：:The increased incidence of malignancies, especially acute leukemia, in Down syndrome has been clearly established. The association of Hodgkin's disease with Down syndrome has not been extensively documented, and only a few cases have been reported. We present here a case report of Hodgkin's disease in an 11-year-old f...

journal_title：Pediatric hematology and oncology

authors： Kusumakumary P,Jyothirmayi R,Chellam VG,Krishnan NM

更新日期：1996-09-01 00:00:00

abstract：:Li-Fraumeni syndrome (LFS) is one of the familial cancers characterized by different tumors and hereditary TP53 mutations. The adrenocortical carcinoma (ACC) association with acute leukemia is unusual in childhood, even in LFS. The authors here present a family with pR337P mutation in TP53 gene who had a child with ac...

journal_title：Pediatric hematology and oncology

authors： Karakas Z,Tugcu D,Unuvar A,Atay D,Akcay A,Gedik H,Kayserili H,Dogan O,Anak S,Devecioglu O

更新日期：2010-05-01 00:00:00

abstract：:A 12-year-old female is reported who presented with right hip pain for 6 months. With massive splenohepatomegaly and leukocytosis, CML was suspected and confirmed on bone-marrow examination and cytogenetics. Further investigations confirmed avascular necrosis (AVN) of the right femoral head. CML was treated by hydroxy...

journal_title：Pediatric hematology and oncology

authors： Kumar S,Bansal D,Prakash M,Sharma P

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:Children with low von Willebrand factor (VWF) activity or type 1 von Willebrand disease (VWD) have increased risk of bleeding after adenotonsillar procedures and the optimal perioperative management to minimize bleeding is unknown. AIM:To report the effectiveness and safety of an institutional protocol in...

journal_title：Pediatric hematology and oncology

authors： Diaz R,Musso M,Mahoney D

更新日期：2020-08-17 00:00:00

abstract：:Objectives: Diffusion-weighted magnetic resonance imaging (DW-MRI) offers potential to monitor response and predict survival in high-grade gliomas (HGG) and diffuse intrinsic pontine gliomas (DIPG). We hypothesized that post-radiotherapy DW-MRI may provide prognostic imaging biomarkers in children and young adults wit...

journal_title：Pediatric hematology and oncology

authors： Carceller F,Jerome NP,Fowkes LA,Khabra K,Mackinnon A,Bautista F,Marshall LV,Vaidya S,Mandeville H,Morgan V,Leach MO,Koh DM

更新日期：2019-03-01 00:00:00

abstract：:Endothelial protein C receptor (EPCR) is primarily localized on the endothelial cells of large blood vessels and is very low or absent in the microvascular endothelium of most tissues. EPCR augments the thrombin/thrombomodulin-dependent activation of protein C by 5- to 20-fold. EPCR appears to be physiologically signi...

journal_title：Pediatric hematology and oncology

authors： Kendirli T,Ciftçi E,Ince E,Yurdakul E,Kansu A,Akar N

更新日期：2007-04-01 00:00:00

abstract：:It is well known in the literature that cancer creates educationally related barriers for all children, which may or may not contribute to clinically relevant school problems. The goal of this study was to obtain a base rate for the characteristic pattern of school functioning for children with leukemia, so that the c...

journal_title：Pediatric hematology and oncology

authors： Adamoli L,Deasy-Spinetta P,Corbetta A,Jankovic M,Lia R,Locati A,Fraschini D,Masera G,Spinetta JJ

更新日期：1997-03-01 00:00:00

abstract：:Two children with inflammatory pseudotumor (IPT) of the lung are reported. Symptomless "cystic" lesions were present on routine chest x ray. Morphological study of these peculiar lesions included light microscopic, immunohistochemical, and ultrastructural analysis. Histologic appearance of the lesion varied from the f...

journal_title：Pediatric hematology and oncology

authors： Vujanić GM,Dojĉinov D

更新日期：1991-04-01 00:00:00

abstract：:The use of G-CSF after myelotoxic chemotherapy accelerates neutrophil recovery reducing the risk of febrile neutropenia. Current guidelines recommend initiating G-CSF 24 hours after myelotoxic chemotherapy. However, the optimal timing of post-chemotherapy G-CSF administration has not been elucidated. Our previous work...

journal_title：Pediatric hematology and oncology

authors： Yankelevich M,Hoogstra DJ,Abrams J,Chu R,Bhambhani K,Taub JW

更新日期：2020-11-01 00:00:00

abstract：:A single institution's experience of three patients with nephroblastoma extending via the inferior vena cava to the right heart is described. The case reports and the pertinent literature illustrate that preoperative failure to detect the intracardial extension increases the risk of right outflow obstruction and pulmo...

journal_title：Pediatric hematology and oncology

authors： Kremens B,Sadony V,Goepel M,Hellinger A,Havers W

更新日期：1991-10-01 00:00:00

abstract：:Arsenic trioxide (ATO) has been proven to be highly effective in adults with newly diagnosed or relapsed acute promyelocytic leukemia (APL). Only very limited data are published on the use of ATO as a single agent for first-line therapy of relapsed APL. The authors present a case of a 8-year-old boy with a bone marrow...

journal_title：Pediatric hematology and oncology

authors： Ebinger M,Schwarze CP,Feuchtinger T,Scheel-Walter HG,Lang P,Hildenbrand S,Gessler P,Handgretinger R

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Alterations in the tumor suppressor gene TP53 have been associated with poor outcome in adult hematological malignancies. We have earlier reported an increased expression of the TP53 encoded protein p53, in bone marrow samples from pediatric patients with aggressive leukemia. Our aim was now to evaluate p53 ...

journal_title：Pediatric hematology and oncology

authors： Honkaniemi E,Mattsson K,Barbany G,Sander B,Gustafsson B

更新日期：2014-05-01 00:00:00

abstract：:A prospective, open-label, randomized, comparative study in pediatric cancer patients was conducted to evaluate the efficacy and safety of cefepime and meropenem in the empiric therapy of febrile neutropenic patients. Febrile episodes were classified as microbiologically documented infection, clinical documented infec...

journal_title：Pediatric hematology and oncology

authors： Oguz A,Karadeniz C,Citak EC,Cil V,Eldes N

更新日期：2006-04-01 00:00:00

abstract：:During the last 5 years massive chemotherapy and autologous bone marrow transplantation have been increasingly explored in the treatment of pediatric solid tumors, mainly for neuroblastoma, Ewing's sarcoma, rhabdomyosarcoma, Wilms' tumor, germ cell tumors, osteosarcoma, and retinoblastoma. Although the disease course ...

journal_title：Pediatric hematology and oncology

authors： Yaniv I,Bouffet E,Irle C,Negrier S,Biron P,Favrot M,Philip I,Brunat-Mentigny M,Philip T

更新日期：1990-01-01 00:00:00

abstract：:A case of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) in infancy is reported. The disease had a mild onset with generalized lymphadenopathy, hepatosplenomegaly, thrombocytopenia, polyclonal hypergammaglobulinemia, and T-cell deficiency. The AILD course lasted more than 100 months, alternating clinica...

journal_title：Pediatric hematology and oncology

authors： de Terlizzi M,Toma MG,Santostasi T,Colella R,Ceci A,De Benedictis G

更新日期：1989-01-01 00:00:00