Long-term remission after first-line single-agent treatment with arsenic trioxide of relapsed acute promyelocytic leukemia in an 8-year-old boy.

abstract：:Ondansetron (Zofron, Glaxo) and tropisetron (Navoban, Sandoz) are selective serotonin (5HT3) antagonists that have proven very effective in the prevention of vomiting and nausea in adults and children receiving cancer chemotherapy. This study compared the efficacy of the two agents in the prevention of vomiting and na...

journal_title：Pediatric hematology and oncology

authors： Stiakaki E,Savvas S,Lydaki E,Bolonaki I,Kouvidi E,Dimitriou H,Kambourakis A,Kalmanti M

更新日期：1999-03-01 00:00:00

abstract：:The aim of this study was to establish reference values and factors associated with serum AFP elevation in infants. Five hundred twenty-four samples collected from infants up to the age of 2 years at the University Hospital Düsseldorf (Germany) were analyzed. At birth mean serum AFP levels were 41,687 ng/ml in 256 ter...

journal_title：Pediatric hematology and oncology

authors： Blohm ME,Vesterling-Hörner D,Calaminus G,Göbel U

更新日期：1998-03-01 00:00:00

abstract：:Chronic granulomatous disease (CGD) is a rare genetically determined immunodeficiency. Neutrophils from CGD patients show a defective killing of phagocytosed fungi and bacteria, due not only to an impairment in oxidative burst, but also to absence of normal pH value within phagocytic vacuole following phagocytosis. Be...

journal_title：Pediatric hematology and oncology

authors： Granzotto M,Leone V,Lepore L,Zerial M,Tommasini A,Ciambra R,Gombac F,Ventura A

更新日期：2005-03-01 00:00:00

abstract：:The reported long-term outcome of endemic Burkitt lymphoma (eBL) patients who present with paraplegia is largely unknown. Records of BL patients treated with comparable short-interval cyclophosphamide chemotherapy schedules between 2004 and 2014 at three Baptist mission hospitals in Cameroon were reviewed. Survivors w...

journal_title：Pediatric hematology and oncology

authors： Hesseling PB,Mbah G,Kouya F,Kimbi C,Nfor P,Kaah J,Kuruvilla R,Best A,Wharin P

更新日期：2015-01-01 00:00:00

abstract：:Anaplastic lymphoma kinase (ALK) inhibitors such as crizotinib and alectinib have been shown to have significant activity in ALK-rearranged non-small cell lung cancers (NSCLC). There are no data for alectinib's safety or efficacy in younger patients, though it is superior to crizotinib in adult trials. We present a 14...

journal_title：Pediatric hematology and oncology

authors： Balzer BWR,Loo C,Wegner EA,Nath CE,Lee S,Smith C,Lewis CR,Trahair TN,Anazodo AC

更新日期：2018-01-01 00:00:00

abstract：:Both transplanted and leukemia patients are at high risk (HR) for invasive pulmonary aspergillosis (IPA). Methods for rapid diagnosis are crucial. Our objective was to investigate the impact of serial serum galactomannan assay (GMA) screening on IPA diagnosis in children. Between January 2010 and December 2011, all ch...

journal_title：Pediatric hematology and oncology

authors： Gefen A,Zaidman I,Shachor-Meyouhas Y,Avidor I,Hakim F,Weyl Ben-Arush M,Kassis I

更新日期：2015-03-01 00:00:00

abstract：:Adolescence is characterized by inter-related physiologic and emotional development. It is a particularly vulnerable period of life culminating into emergence as an adult. The majority of malignant bone tumors in pediatrics affect the adolescent patient. As a part of the treatment, amputation may be required for cure....

journal_title：Pediatric hematology and oncology

authors： Jaffe N,Zietz H

更新日期：2004-09-01 00:00:00

abstract：:A 20-year-old female developed a relapse of B-precursor acute lymphoblastic leukemia (ALL) as a mass in her left breast after 6 years of maintained continuous complete remission. No leukemic lesions were identified in other sites such as the bone marrow or cerebrospinal fluid. The relapsed leukemic cells in the breast...

journal_title：Pediatric hematology and oncology

authors： Todo K,Morimoto A,Osone S,Nukina S,Ohtsuka T,Ishida H,Yoshihara T,Todo S

更新日期：2008-09-01 00:00:00

abstract：:Eighty-six patients with Ewing's sarcoma were analyzed as to the role of radiation therapy. Fifty-eight patients (P group) had removal of the involved part of the bone after preoperative chemotherapy, and 28 (NP group) had local treatment either at the same time or before chemotherapy. Thirty-six of 58 P-group patient...

journal_title：Pediatric hematology and oncology

authors： Jereb B,Ong RL,Mohan M,Caparros B,Exelby P

更新日期：1986-01-01 00:00:00

abstract：:Infantile hemangioendothelioma is the most common hepatic vascular tumor in infants less than 6 months of age, with a prevalence of 1%. Serum alpha-fetoprotein levels have been used as an important tumor marker for hepatoblastoma, hepatocellular carcinoma, and germ cell tumors. It is rarely elevated in hepatic hemangi...

journal_title：Pediatric hematology and oncology

authors： Sari N,Yalçin B,Akyüz C,Haliloglu M,Büyükpamukçu M

更新日期：2006-12-01 00:00:00

abstract：:The authors report their experience with 70 pediatric patients with spinal cord compression (SCC) due to malignancies identified among 898 patients with solid tumors. An extradural tumor was the most frequent cause of SCC (71%); 54% of these were soft tissue sarcomas and neuroblastoma. Most intradural tumors (70%) wer...

journal_title：Pediatric hematology and oncology

authors： Pollono D,Tomarchia S,Drut R,Ibañez O,Ferreyra M,Cédola J

更新日期：2003-09-01 00:00:00

abstract：:Neutropenic enterocolitis is an acute, life-threatening inflammation of the small and large bowel, often seen in children with malignancies during periods of prolonged or severe neutropenia. During the period 1990-1995, 180 children were treated at the authors' center for acute lymphoblastic leukemia using a standard ...

journal_title：Pediatric hematology and oncology

authors： Jain Y,Arya LS,Kataria R

更新日期：2000-01-01 00:00:00

abstract：:Growth hormone deficiency (GHD) is a recognized late effect of successful treatment of tumors requiring cranial irradiation. Growth after treatment was assessed in 16 patients with sarcomas of the orbital and parameningeal regions. Median age at diagnosis was 6.35 years and median follow-up was 7.2 years. Treatment co...

journal_title：Pediatric hematology and oncology

authors： Goddard AG,Harris SJ,Plowman PN,Savage MO,Kingston JE

更新日期：1999-01-01 00:00:00

abstract：:The objective of this study is to analyze the major causes of abnormal findings seen in the preoperative coagulation tests of asymptomatic pediatric patients and to discuss the usefulness of coagulation tests prior to minor surgery. Among patients who received minor surgery in Kyung Hee University Medical Center from ...

journal_title：Pediatric hematology and oncology

authors： Kang S,Yoon HS,Lee EH

更新日期：2016-05-01 00:00:00

abstract：:Increased susceptibility to infection is reported in patients with beta-thalassemia major due to toxic effect of iron on neutrophil functions and reticuloendothelial system dysfunction. This study investigated the association between the neutrophil apoptosis and frequency of infection episodes, desferrioxamine treatme...

journal_title：Pediatric hematology and oncology

authors： Oren H,Sahin B,Irken G,Ateş H,Duman M,Yilmaz S,Türker M,Atabay B,Yaprak I

更新日期：2003-04-01 00:00:00

abstract：:Acute basophilic leukemia is a distinct entity of Acute Myeloid Leukemia (AML) with primary differentiation to basophils. Increased basophil count has been described in AML cases with translocation t(6;9)(p23;q34) or other chromosomal abnormalities. We describe a 15-year old female teenager with AML and excess periphe...

journal_title：Pediatric hematology and oncology

authors： Servitzoglou M,Grenzelia M,Baka M,Harisi M,Pourtsidis A,Bouhoutsou D,Varvoutsi M,Doganis D,Dana H,Divane A,Kosmidis H

更新日期：2014-03-01 00:00:00

abstract：:There are limited studies that have focused on the causes for hospitalization as an indicator of morbidity in patients with β-thalassemia major (BTM). A cross-sectional study was conducted to determine the main causes for hospitalization and death in hospitalized BTM patients in a referral hospital in Shiraz, southern...

journal_title：Pediatric hematology and oncology

authors： Bazrgar M,Peiravian F,Abedpour F,Karimi M

更新日期：2011-03-01 00:00:00

abstract：:The clinical usefulness of the measurement of red cell zinc protoporphyrin (ZPP), an indicator of iron-deficient erythropoiesis, was assessed in a group of UK children undergoing investigation for red cell microcytosis. Of 213 children studied, 136 had increased ZPP values. Of these, 86 also had reduced iron stores as...

journal_title：Pediatric hematology and oncology

authors： Hinchliffe RF,Lilleyman JS,Steel GJ,Bellamy GJ

更新日期：1995-09-01 00:00:00

abstract：:Li-Fraumeni syndrome (LFS) is one of the familial cancers characterized by different tumors and hereditary TP53 mutations. The adrenocortical carcinoma (ACC) association with acute leukemia is unusual in childhood, even in LFS. The authors here present a family with pR337P mutation in TP53 gene who had a child with ac...

journal_title：Pediatric hematology and oncology

authors： Karakas Z,Tugcu D,Unuvar A,Atay D,Akcay A,Gedik H,Kayserili H,Dogan O,Anak S,Devecioglu O

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:To describe clinical and CT features of L-asparaginase-associated pancreatitis (L-AP) and to correlate CT grades with clinical parameters. METHODS:A total of 16 children (M:F = 9:7; mean age, 8.1 years) who developed L-AP after L-asparaginase (L-asp) treatment and underwent abdominal CT scan were included. We ...

journal_title：Pediatric hematology and oncology

authors： Oh HJ,Im SA,Lee JW,Chung NG,Cho B

更新日期：2014-10-01 00:00:00

abstract：:The study assessed changes in cerebral blood flow and need for chronic blood transfusions in sickle cell disease children after splenectomy. A retrospective chart review of 40 children splenectomized between 1999 and 2014 was performed. The mean time-average maximum velocity before splenectomy was 129 cm/sec; which in...

journal_title：Pediatric hematology and oncology

authors： Siddiqui AH,Soh PB

更新日期：2015-05-01 00:00:00

abstract：:Disaccharidases activity in the intestinal mucosa samples of rats was examined after intragastric and intramuscular methotrexate therapy. Methotrexate was given on a twice a week schedule (1 mg/kg body weight). The animals were sacrificed after 2 weeks, 1 month, and 2 months of this therapy. A statistically significan...

journal_title：Pediatric hematology and oncology

authors： Dyduch A,Steplewski Z,Koehler M,Piszka B

更新日期：1990-01-01 00:00:00

abstract：:Background: Preclinical studies show that TLR9 agonists can eradicate leukemia by induction of immune responses in vivo against AML and ALL. These studies demonstrated that TLR9 agonists induce an immediate NK response followed by adaptive T and B cells responses resulting in long term anti-leukemia immunity. Methods:...

journal_title：Pediatric hematology and oncology

authors： Ronsley R,Kariminia A,Ng B,Mostafavi S,Reid G,Subrt P,Hijiya N,Schultz KR

更新日期：2019-11-01 00:00:00

abstract：:Histone deacetylase inhibitors (HDACis) are epigenetic agents that display antitumor activities in experimental medulloblastoma (MB). Fingolimod (FTY720), an immunosuppressant agent currently used in the treatment of multiple sclerosis, also has anticancer actions and can act as an HDACi. Here we examined whether fing...

journal_title：Pediatric hematology and oncology

authors： Perla AS,Fratini L,Cardoso PS,de Farias CB,da Cunha Jaeger M,Roesler R

更新日期：2020-03-01 00:00:00

abstract：:Maternal education might be an important factor for the neuroblastoma risk in children, but it was conflicting. This meta-analysis was performed to evaluate the relationship between maternal education and neuroblastoma susceptibility and to explore whether maternal education was an important indicator to be associated...

journal_title：Pediatric hematology and oncology

authors： Wang P,Liao N,Liao XH,Liang B,Huang CX,Li W

更新日期：2013-02-01 00:00:00

abstract：:We report the outcome of 27 children with de novo acute megakaryoblastic leukemia (AMKL) (excluding Down syndrome) enrolled in the French multicenter prospective study ELAM02 (2005-2011). There was no difference in gender, initial leukocyte count, CNS involvement, and complete remission rate (88.9%), as compared to ot...

journal_title：Pediatric hematology and oncology

authors： Teyssier AC,Lapillonne H,Pasquet M,Ballerini P,Baruchel A,Ducassou S,Fenneteau O,Petit A,Cuccuini W,Ragu C,Preudhomme C,Mercher T,Sirvent N,Leverger G

更新日期：2017-11-01 00:00:00

abstract：:To evaluate the quantitative aspects of the shift in production from fetal hemoglobin (HbF) to adult hemoglobin (HbA), the HbF and HbA mass were estimated in a preterm infant (gestational age 29 weeks) for 22 weeks after an exchange transfusion the second day of life, leading to an initial HbA% of 100. Up until the es...

journal_title：Pediatric hematology and oncology

authors： Refsum HE,Bechensteen AG,Lindemann R

更新日期：1998-09-01 00:00:00

abstract：:Endothelial protein C receptor (EPCR) is primarily localized on the endothelial cells of large blood vessels and is very low or absent in the microvascular endothelium of most tissues. EPCR augments the thrombin/thrombomodulin-dependent activation of protein C by 5- to 20-fold. EPCR appears to be physiologically signi...

journal_title：Pediatric hematology and oncology

authors： Kendirli T,Ciftçi E,Ince E,Yurdakul E,Kansu A,Akar N

更新日期：2007-04-01 00:00:00

abstract：:A 2-year-old girl with acute lymphoblastic leukemia (ALL) showing a t(4;11)(q21;q23) karyotype underwent allogeneic bone marrow transplantation (BMT) with the conditioning regimen of L-PAM (70 mg/m2/d for 3 days), busulfan (140 mg/m2/d for 2 days), and total body irradiation (12 Gy). On day 57, the patient developed p...

journal_title：Pediatric hematology and oncology

authors： Takanashi M,Hibi S,Todo S,Sawada T,Tsunamoto K,Imashuku S

更新日期：1998-01-01 00:00:00

abstract：:Tolerance of full-dose methotrexate/6-mercaptopurine (MTX/6MP) maintenance therapy for childhood acute lymphoblastic leukemia (ALL) without side effects could reflect insufficient systemic drug exposure, and drug withdrawals due to toxicity might reduce the chance of cure. The present study included 122 children with ...

journal_title：Pediatric hematology and oncology

authors： Schmiegelow K

更新日期：1991-10-01 00:00:00