Hodgkin's disease in association with Down syndrome: a case report.

Abstract:

:The increased incidence of malignancies, especially acute leukemia, in Down syndrome has been clearly established. The association of Hodgkin's disease with Down syndrome has not been extensively documented, and only a few cases have been reported. We present here a case report of Hodgkin's disease in an 11-year-old female child with Down syndrome. The child presented with a stage IVB nodular sclerotic Hodgkin's disease and died of progressive disease. We also present a brief review of the mechanisms of development of malignancy in Down syndrome.

journal_name

Pediatr Hematol Oncol

authors

Kusumakumary P,Jyothirmayi R,Chellam VG,Krishnan NM

doi

10.3109/08880019609030860

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

469-71

issue

5

eissn

0888-0018

issn

1521-0669

journal_volume

13

pub_type

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