Central nervous system (CNS) tumors in the first six months of life: the Children's Hospital Los Angeles experience, 1979-2005.

Abstract:

BACKGROUND:The authors report the experience at the Children's Hospital Los Angeles with brain tumors diagnosed before 6 months of age, describing the characteristics of the patients, their tumors, treatment strategies, and prognostic factors. METHODS:Thirty-three children who were identified between 1979 and 2005 were included. Twelve were female (36%). There were 11 gliomas, 9 choroid plexus tumors, 8 medulloblastomas and supratentorial primitive neuroectodermal tumors (PNET), 2 atypical teratoid/rhabdoid tumors (ATRT), and 1 each of ependymoma, craniopharyngioma, and immature teratoma. Locations of primary tumors included 21 supratentorial (64%) and 7 posterior fossa, and 5 tumors involved both compartments. The treatment strategies included 5 patients with biopsy only, 18 less than gross total resections (

journal_name

Pediatr Hematol Oncol

authors

Serowka K,Chiu Y,Gonzalez I,Gilles F,McComb G,Krieger M,Dhall G,Britt B,Ji L,Sposto R,Finlay JL

doi

10.3109/08880010903447342

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

90-102

issue

2

eissn

0888-0018

issn

1521-0669

journal_volume

27

pub_type

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