Initial Management of Childhood Acute Immune Thrombocytopenia: Single-Center Experience of 32 Years.

abstract：:Immune thrombocytopenia (ITP) is a frequently encountered disease in childhood. Recent reports pointed to the benefit of high-dose steroid in ITP treatment since it resulted in a better outcome in a shorter time than IV immunoglobulin therapy. In the authors' clinic, mainly after 1984, megadose methyl prednisolone (MD...

journal_title：Pediatric hematology and oncology

authors： Yetgin S,Yenicesu IC,Ersoy F

更新日期：2005-07-01 00:00:00

abstract：:Osteoporosis is common in patients with thalassemia major. A 16-year-old patient with thalassemia major was referred for evaluation of osteoporosis. The results of dual-energy X-ray absorptiometry in a patient with thalassemia major are presented. The patient underwent measurements of the spine in both AP and lateral ...

journal_title：Pediatric hematology and oncology

authors： Yildiz M,Canatan D

更新日期：2005-12-01 00:00:00

abstract：:The authors report the results of 58 children with ALL in 2CR after related (n = 31) or unrelated (n = 27) AHSCT. Characteristics at diagnosis and initial and after relapse antileukemic treatment were similar in the related donor (RD) and the unrelated donor (UD) groups. Conditioning consisted of TBI/CY +/- VP-16 for ...

journal_title：Pediatric hematology and oncology

authors： Muñoz A,Diaz-Heredia C,Diaz MA,Badell I,Verdeguer A,Martinez A,Gomez P,Perez-Hurtado JM,Bureo E,Fernandez-Delgado R,Gonzalez-Valentin ME,Maldonado MS

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:Recent guidelines recommend to assess emotional distress in pediatric oncology during treatment and in after care. One tool used to do this is the distress thermometer (DT), a simple tool which has almost exclusively been studied in its screening abilities. Given its increased used as a measure of distress p...

journal_title：Pediatric hematology and oncology

authors： Pépin AJ,Lippé S,Krajinovic M,Laverdière C,Michon B,Sinnett D,Sultan S

更新日期：2017-04-01 00:00:00

abstract：:We evaluated serum C-reactive protein (CRP) level and serum sodium concentration as early indicators of bacteremia in neutropenic children in two different series in 1983-1984 (49 bacteremias) and 1989-1990 (29 bacteremias). During the earlier period, the goal was to avoid unnecessary antimicrobial therapy. Currently ...

journal_title：Pediatric hematology and oncology

authors： Riikonen P,Saarinen UM,Perkkiö M,Hovi L,Siimes MA

更新日期：1992-10-01 00:00:00

abstract：:Neuroblastoma is the most common solid tumor in childhood and is the most frequent neural crest tumor (NCT). More than 90% of the patients excrete high levels of vanilmandelic acid (VMA) and homovanillic acid (HVA) in the urine. Original biochemical methods for measuring these two metabolites of catecholamines employe...

journal_title：Pediatric hematology and oncology

authors： Gregianin LJ,McGill AC,Pinheiro CM,Brunetto AL

更新日期：1997-05-01 00:00:00

abstract：:The reported long-term outcome of endemic Burkitt lymphoma (eBL) patients who present with paraplegia is largely unknown. Records of BL patients treated with comparable short-interval cyclophosphamide chemotherapy schedules between 2004 and 2014 at three Baptist mission hospitals in Cameroon were reviewed. Survivors w...

journal_title：Pediatric hematology and oncology

authors： Hesseling PB,Mbah G,Kouya F,Kimbi C,Nfor P,Kaah J,Kuruvilla R,Best A,Wharin P

更新日期：2015-01-01 00:00:00

abstract：:Neuroblastoma presenting with obstructive jaundice is a rare event. Management of this condition includes surgery, chemotherapy, radiotherapy, temporary cholecystostomy tube, endoscopic retrograde cholangiopancreatography (ERCP), and internal biliary drainage (IBD). We herein describe our experience with one infant af...

journal_title：Pediatric hematology and oncology

authors： Saettini F,Agazzi R,Giraldi E,Foglia C,Cavalleri L,Morali L,Fasolini G,Spotti A,Provenzi M

更新日期：2015-04-01 00:00:00

abstract：:A 2-year-old girl with acute lymphoblastic leukemia (ALL) showing a t(4;11)(q21;q23) karyotype underwent allogeneic bone marrow transplantation (BMT) with the conditioning regimen of L-PAM (70 mg/m2/d for 3 days), busulfan (140 mg/m2/d for 2 days), and total body irradiation (12 Gy). On day 57, the patient developed p...

journal_title：Pediatric hematology and oncology

authors： Takanashi M,Hibi S,Todo S,Sawada T,Tsunamoto K,Imashuku S

更新日期：1998-01-01 00:00:00

abstract：:Ataxia-telangiectasia is an autosomal recessive disease characterized by progressive cerebellar ataxia, oculocutaneous telangiectasia, immunodeficiency, high incidence of cancer, and increased sensitivity to ionizing radiation. The authors report a case of dysgerminoma in a child with high alpha-fetoprotein, CA125 and...

journal_title：Pediatric hematology and oncology

authors： Koksal Y,Caliskan U,Ucar C,Yurtcu M,Artac H,Ilerisoy-Yakut Z,Reisli I

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:Chronic liver disease causes a disruption of procoagulant and anticoagulant factors, resulting in a fragile state, prone to increased rates of both bleeding and thrombosis. Currently, there is limited literature describing the changes observed in pediatric liver disease and extrahepatic portal vein obstruc...

journal_title：Pediatric hematology and oncology

authors： Beattie W,Magnusson M,Hardikar W,Monagle P,Ignjatovic V

更新日期：2017-03-01 00:00:00

abstract：:Treatment of Langerhans cell histiocytosis (LCH) is yet to be established. We treated seven patients with etoposide alone at a dose of 100 mg/m2/day for 3 days given every 3 to 4 weeks for six cycles. Three patients had received prior chemotherapy, two patients were less than 2 years of age, and two had liver dysfunct...

journal_title：Pediatric hematology and oncology

authors： Basade MM,Nair CN,Kurkure PA,Pai SK,Advani SH

更新日期：1996-03-01 00:00:00

abstract：:Renal and metabolic complications of tumor lysis syndrome (TLS) were recognized frequently in the 1960s and 1970s. Strategies were designed to prevent TLS. We conducted a retrospective chart review study to identify the current TLS risk in children with acute leukemia. Children were considered to have "laboratory tumo...

journal_title：Pediatric hematology and oncology

authors： Kedar A,Grow W,Neiberger RE

更新日期：1995-03-01 00:00:00

abstract：:Endothelial protein C receptor (EPCR) is primarily localized on the endothelial cells of large blood vessels and is very low or absent in the microvascular endothelium of most tissues. EPCR augments the thrombin/thrombomodulin-dependent activation of protein C by 5- to 20-fold. EPCR appears to be physiologically signi...

journal_title：Pediatric hematology and oncology

authors： Kendirli T,Ciftçi E,Ince E,Yurdakul E,Kansu A,Akar N

更新日期：2007-04-01 00:00:00

abstract：:This study investigated the influence of levamisole therapy on immunocompetent cells and lymphocyte reactivity to mitogens in 25 children with brain tumor. Eleven (11/25) patients were receiving chemotherapy and immunomodulating drug levamisole 3 months after neurosurgery, during maintenance chemotherapy, 2.5 mg/kg of...

journal_title：Pediatric hematology and oncology

authors： Hajnzić TF,Kastelan M,Lukac J,Hajnzić T

更新日期：1999-07-01 00:00:00

abstract：:Medulloblastoma (MB) is a cancer of the cerebellum and the most common primary pediatric malignancy of the central nervous system. Classified as a primitive neural ectoderm tumor; it is thought to arise from granule cell precursors in the cerebellum. The standard of care consists of surgery, chemotherapy and age-depen...

journal_title：Pediatric hematology and oncology

authors： Byrd T,Grossman RG,Ahmed N

更新日期：2012-09-01 00:00:00

abstract：:The increased incidence of malignancies, especially acute leukemia, in Down syndrome has been clearly established. The association of Hodgkin's disease with Down syndrome has not been extensively documented, and only a few cases have been reported. We present here a case report of Hodgkin's disease in an 11-year-old f...

journal_title：Pediatric hematology and oncology

authors： Kusumakumary P,Jyothirmayi R,Chellam VG,Krishnan NM

更新日期：1996-09-01 00:00:00

abstract：:Factor X (FX) is the component of both extrinsic and intrinsic coagulation cascade and is the first enzyme of the common pathway which results in thrombus. Congenital FX deficiency (FXD) is an extremely rare coagulation defect. In this study, we aimed to investigate the clinical and laboratory data of the patients dia...

journal_title：Pediatric hematology and oncology

authors： Karabel M,Söker M,Yıldırım AT,Oymak Y,Kelekçi S,Karabel D

更新日期：2013-11-01 00:00:00

abstract：:Twenty-eight children with HSP and 79 healthy children were entered into study. Activities of protein C, free-protein S and antithrombin, activated protein C resistance, levels of fibrinogen. D-dimer, thrombin-antithrombin complex (TAT), prothrombin fragments 1 + 2 (PF(1+2)), and von Willebrand factor antigen (vWAg) a...

journal_title：Pediatric hematology and oncology

authors： Yilmaz D,Kavakli K,Ozkayin N

更新日期：2005-01-01 00:00:00

abstract：:The aim of this study was to investigate the impact of therapy on long-term gonadal function of young people cured of childhood lymphomas and to assess whether a prepubertal state during the treatment protects the gonads from chemotherapy and/or radiotherapy late effects. Clinical evaluation, semen analysis, and endoc...

journal_title：Pediatric hematology and oncology

authors： Ben Arush MW,Solt I,Lightman A,Linn S,Kuten A

更新日期：2000-04-01 00:00:00

abstract：:Anaplastic lymphoma kinase (ALK) inhibitors such as crizotinib and alectinib have been shown to have significant activity in ALK-rearranged non-small cell lung cancers (NSCLC). There are no data for alectinib's safety or efficacy in younger patients, though it is superior to crizotinib in adult trials. We present a 14...

journal_title：Pediatric hematology and oncology

authors： Balzer BWR,Loo C,Wegner EA,Nath CE,Lee S,Smith C,Lewis CR,Trahair TN,Anazodo AC

更新日期：2018-01-01 00:00:00

abstract：:Endocrine system dysfunctions are the significant complications of excessive iron overload in beta thalassemia patients. The aim of this study was to evaluate the long-term effect of chelation with deferasirox on endocrine complications. The study group consisted of children with beta thalassemia who had been evaluate...

journal_title：Pediatric hematology and oncology

authors： Bilgin BK,Yozgat AK,Isik P,Çulha V,Kacar D,Kara A,Ozbek NY,Yarali N

更新日期：2020-09-01 00:00:00

abstract：:A single institution's experience of three patients with nephroblastoma extending via the inferior vena cava to the right heart is described. The case reports and the pertinent literature illustrate that preoperative failure to detect the intracardial extension increases the risk of right outflow obstruction and pulmo...

journal_title：Pediatric hematology and oncology

authors： Kremens B,Sadony V,Goepel M,Hellinger A,Havers W

更新日期：1991-10-01 00:00:00

abstract：:We investigated bone marrow (BM) recovery of hematopoietic stem cells (HSC) and hematopoietic microenvironment after chemotherapy in childhood acute lymphoblastic leukemia (ALL). Twenty-nine de novo childhood ALL patients were enrolled and BM biopsy sections at diagnosis (BM0), after induction (BM1), consolidation (BM...

journal_title：Pediatric hematology and oncology

authors： Park SH,Lee MJ,Park CJ,Jang S,Seo EJ,Im HJ,Seo JJ

更新日期：2019-05-01 00:00:00

abstract：:Between 1973 and 1991, 10 patients with locally advanced [stages III and IV] nasopharyngeal carcinoma were treated at the Northern Israel Oncology Center. All patients were treated with wide-field irradiation to the primary tumor, including the base of skull, neck, and supraclavicular region. After 1984, 6 patients al...

journal_title：Pediatric hematology and oncology

authors： Arush MW,Stein ME,Rosenblatt E,Lavie R,Kuten A

更新日期：1995-05-01 00:00:00

abstract：:To evaluate the quantitative aspects of the shift in production from fetal hemoglobin (HbF) to adult hemoglobin (HbA), the HbF and HbA mass were estimated in a preterm infant (gestational age 29 weeks) for 22 weeks after an exchange transfusion the second day of life, leading to an initial HbA% of 100. Up until the es...

journal_title：Pediatric hematology and oncology

authors： Refsum HE,Bechensteen AG,Lindemann R

更新日期：1998-09-01 00:00:00

abstract：:Ondansetron (Zofron, Glaxo) and tropisetron (Navoban, Sandoz) are selective serotonin (5HT3) antagonists that have proven very effective in the prevention of vomiting and nausea in adults and children receiving cancer chemotherapy. This study compared the efficacy of the two agents in the prevention of vomiting and na...

journal_title：Pediatric hematology and oncology

authors： Stiakaki E,Savvas S,Lydaki E,Bolonaki I,Kouvidi E,Dimitriou H,Kambourakis A,Kalmanti M

更新日期：1999-03-01 00:00:00

abstract：:An episode of transient encephalopathy after the first course of intravenous high-dose methotrexate (HD-MTX; 1000 mg/m2) was observed in a 4-year-old girl with acute lymphoblastic leukemia. The neurological abnormalities took place 5 days after HD-MTX therapy. She experienced complex partial seizure and left hemipares...

journal_title：Pediatric hematology and oncology

authors： Kubo M,Azuma E,Arai S,Komada Y,Ito M,Sakurai M

更新日期：1992-04-01 00:00:00

abstract：:A major problem of hemophilia A (HA) treatment is the development of factor VIII (FVIII) inhibitor, which usually occurs shortly after initiating replacement therapy. Several studies showed the correlation between inhibitor development and polymorphisms in inflammatory and immune response genes of HA patients; however...

journal_title：Pediatric hematology and oncology

authors： Naderi N,Yousefi H,Mollazadeh S,Seyed Mikaeili A,Keshavarz Norouzpour M,Jazebi M,Moazezi Nekooi Asl SS,Namvar A,Azizi Saraji A,Agi E,Bolhassani A

更新日期：2019-02-01 00:00:00

abstract：:We present the management challenge provided by a patient with kaposiform hemangioendothelioma associated with Kasabach-Merritt phenomenon. A female child presented at 14 months of age with an ecchymotic swelling of her right upper arm and axilla. Subsequently, she developed profound thrombocytopenia and hypofibrinoge...

journal_title：Pediatric hematology and oncology

authors： Blei F,Karp N,Rofsky N,Rosen R,Greco MA

更新日期：1998-07-01 00:00:00