Clinical value of RAG1 expression and IKZF1 deletions in Philadelphia negative pediatric B cell precursor acute lymphoblastic leukemia.

abstract：:Ondansetron (Zofron, Glaxo) and tropisetron (Navoban, Sandoz) are selective serotonin (5HT3) antagonists that have proven very effective in the prevention of vomiting and nausea in adults and children receiving cancer chemotherapy. This study compared the efficacy of the two agents in the prevention of vomiting and na...

journal_title：Pediatric hematology and oncology

authors： Stiakaki E,Savvas S,Lydaki E,Bolonaki I,Kouvidi E,Dimitriou H,Kambourakis A,Kalmanti M

更新日期：1999-03-01 00:00:00

abstract：:The objective of this study is to analyze the major causes of abnormal findings seen in the preoperative coagulation tests of asymptomatic pediatric patients and to discuss the usefulness of coagulation tests prior to minor surgery. Among patients who received minor surgery in Kyung Hee University Medical Center from ...

journal_title：Pediatric hematology and oncology

authors： Kang S,Yoon HS,Lee EH

更新日期：2016-05-01 00:00:00

abstract：:Very little has been published on the use of romiplostim to treat primary immune thrombocytopenia (ITP), refractory to previous treatments, in children. The objective of this study was to determine its efficacy and safety in pediatric patients in a university general hospital. Retrospective, longitudinal observational...

journal_title：Pediatric hematology and oncology

authors： Escudero Vilaplana V,Aragonés JH,Fernández-Llamazares CM,Bieler CB,Rodríguez SM,Sáez MS

更新日期：2012-03-01 00:00:00

abstract：:Growth was studied longitudinally in 19 children who were long-term survivors after acute lymphoblastic leukemia (ALL). Of the children, 13 were girls; 6 were boys. They had all undergone a 3-year cytostatic treatment period which included vincristine, adriamycin, asparaginase, methotrexate, purinethol, and prednisone...

journal_title：Pediatric hematology and oncology

authors： Sempoux P,Moëll C,Cornu G,Malvaux P,Maes M

更新日期：1992-07-01 00:00:00

abstract：:Sinovenous thrombosis describes thrombosis in one or more of the cerebral venous sinuses. The incidence of SVT in childhood appears to be highest during the neonatal period. Although plasma level of D-dimer has been shown to be sensitive for the diagnosis of deep vein thrombosis and pulmonary embolism in adult patient...

journal_title：Pediatric hematology and oncology

authors： Karagöl BS,Erdeve O,Fítöz S,Uysal Z,Atasay B,Arsan S

更新日期：2007-07-01 00:00:00

abstract：:A case of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) in infancy is reported. The disease had a mild onset with generalized lymphadenopathy, hepatosplenomegaly, thrombocytopenia, polyclonal hypergammaglobulinemia, and T-cell deficiency. The AILD course lasted more than 100 months, alternating clinica...

journal_title：Pediatric hematology and oncology

authors： de Terlizzi M,Toma MG,Santostasi T,Colella R,Ceci A,De Benedictis G

更新日期：1989-01-01 00:00:00

abstract：:The authors sought to determine prevalence, social, economic, and dietary patterns of young children (n = 20) identified as having vitamin B12 deficiency anemia after admission to their hospital in the last 3 years. The diagnosis of vitamin B12 deficiency was based on symptoms and clinical findings, findings on periph...

journal_title：Pediatric hematology and oncology

authors： Cetinkaya F,Yildirmak Y,Kutluk G,Erdem E

更新日期：2007-01-01 00:00:00

abstract：:Renal and metabolic complications of tumor lysis syndrome (TLS) were recognized frequently in the 1960s and 1970s. Strategies were designed to prevent TLS. We conducted a retrospective chart review study to identify the current TLS risk in children with acute leukemia. Children were considered to have "laboratory tumo...

journal_title：Pediatric hematology and oncology

authors： Kedar A,Grow W,Neiberger RE

更新日期：1995-03-01 00:00:00

abstract：:We investigated bone marrow (BM) recovery of hematopoietic stem cells (HSC) and hematopoietic microenvironment after chemotherapy in childhood acute lymphoblastic leukemia (ALL). Twenty-nine de novo childhood ALL patients were enrolled and BM biopsy sections at diagnosis (BM0), after induction (BM1), consolidation (BM...

journal_title：Pediatric hematology and oncology

authors： Park SH,Lee MJ,Park CJ,Jang S,Seo EJ,Im HJ,Seo JJ

更新日期：2019-05-01 00:00:00

abstract：UNLABELLED:Intravenous (IV) ferric iron (Fe)-carbohydrate complexes are used for treating Fe deficiency in children with iron-refractory iron-deficiency anemia (IRIDA). An optimal treatment has yet to be determined. There are relatively little publications on the responsiveness to IV iron therapy in children with IRIDA...

journal_title：Pediatric hematology and oncology

authors： Akin M,Atay E,Oztekin O,Karadeniz C,Karakus YT,Yilmaz B,Erdogan F

更新日期：2014-02-01 00:00:00

abstract：:Two children are described who presented with fever and generalized seizures, days 50 and 200, respectively, after matched unrelated donor-bone marrow transplantation. Upon antiepileptic treatment the seizures vanished but somnolence and fever remained. Magnetic resonance imaging (MRI) of the brain was performed and r...

journal_title：Pediatric hematology and oncology

authors： Fischmeister G,Wiesbauer P,Holzmann HM,Peters C,Eibl M,Gadner H

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:Venous thrombotic events (VTE) are a well-recognized complication in pediatric cancer patients. Population-based data on the incidence and characteristics of VTE in all pediatric cancer patients are limited. This information is crucial to identify patients at high risk and design targeted interventions accord...

journal_title：Pediatric hematology and oncology

authors： Asyyed Z,MacDonald T,Digout C,Kulkarni K

更新日期：2017-03-01 00:00:00

abstract：:We have read, with great interest, the recent article by Lee. In this excellent study, the authors investigated the association between vitamin D deficiency and anemia in a nationally representative sample of Korean children and adolescents. They concluded that vitamin D deficiency is associated with increased risk of...

journal_title：Pediatric hematology and oncology

authors： Kartal Ö,Kartal AT

更新日期：2015-01-01 00:00:00

abstract：:In this paper we describe a 9-year-old girl with abdominal embryonal rhabdomyosarcoma. She had ascites and widespread metastatic disease at presentation and was oliguric but had a normal creatinine. Following the start of chemotherapy she developed acute renal failure secondary to the tumor lysis syndrome, requiring h...

journal_title：Pediatric hematology and oncology

authors： Khan J,Broadbent VA

更新日期：1993-04-01 00:00:00

abstract：:Adrenocortical carcinoma (ACC) is a rare, aggressive endocrine neoplasm. Complete surgical resection is the single most important treatment. Most available information has been learned from experience with its more frequent adult counterpart. In this study, we assessed the features and survival outcome of patients wit...

journal_title：Pediatric hematology and oncology

authors： Zekri W,Hammad M,Rashed WM,Ahmed G,Elshafie M,Adly MH,Elborai Y,Abdalla B,Taha H,Elkinaae N,Refaat A,Younis A,Alfaar AS

更新日期：2020-04-01 00:00:00

abstract：:The treatment of pediatric severe aplastic anemia (SAA) with allogeneic hematopoietic stem cell transplantation (allo-HSCT), presents major challenges including the risks of graft failure, septic complications, and graft-versus-host disease (GVHD). Additive infusions of human umbilical cord derived mesenchymal stem ce...

journal_title：Pediatric hematology and oncology

authors： Si Y,Yang K,Qin M,Zhang C,Du Z,Zhang X,Liu Y,Yue Y,Feng Z

更新日期：2014-02-01 00:00:00

abstract：:Metastatic osteosarcoma most commonly affects the lungs and other bones. Hepatic metastasis at the time of diagnosis is extremely rare. A 14-year-old boy with synovial sarcoma of the left popliteal fossa was treated with surgical resection, radiotherapy for microscopic residual disease, and 1 year of chemotherapy (vin...

journal_title：Pediatric hematology and oncology

authors： Daw NC,Kaste SC,Hill DA,Kun LE,Pratt CB

更新日期：2001-03-01 00:00:00

abstract：:Blast cell chromosome abnormalities at presentation in childhood acute lymphoblastic leukemia (ALL) are common, and different patterns are known to be related to outcome. In contrast, the frequency and importance of further changes at the time of relapse remain unclear. Blast cell karyotype evolution was therefore stu...

journal_title：Pediatric hematology and oncology

authors： Vora AJ,Potter AM,Anderson LM,Lilleyman JS

更新日期：1994-07-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) seems to play a central role in angiogenesis-lymphangiogenesis in hematological malignancies. There are limited data related to childhood hematologic malignancies. The aim of the study was to evaluate soluble VEGF (sVEGF) levels in children with acute leukemia and malignant ly...

journal_title：Pediatric hematology and oncology

authors： Dincaslan HU,Yavuz G,Unal E,Tacyildiz N,Ikinciogullari A,Dogu F,Guloglu D,Yuksek N,Ertem U

更新日期：2010-10-01 00:00:00

abstract：:Invasive fungal infection continues to pose a significant threat to immunocompromised patients, with cerebral aspergillosis being among the most feared ones. The authors describe an adolescent girl with acute lymphoblastic leukemia (ALL) with subsequent acute liver failure, who developed an aspergillus brain abscess. ...

journal_title：Pediatric hematology and oncology

authors： Sterba J,Prochazka J,Ventruba J,Kren L,Valik D,Burgetova D,Mudry P,Skotakova J,Blatny J

更新日期：2005-12-01 00:00:00

abstract：:We present the management challenge provided by a patient with kaposiform hemangioendothelioma associated with Kasabach-Merritt phenomenon. A female child presented at 14 months of age with an ecchymotic swelling of her right upper arm and axilla. Subsequently, she developed profound thrombocytopenia and hypofibrinoge...

journal_title：Pediatric hematology and oncology

authors： Blei F,Karp N,Rofsky N,Rosen R,Greco MA

更新日期：1998-07-01 00:00:00

abstract：:Hepatoblastoma, the commonest primary malignant liver tumor in infants and children, is usually associated with elevated serum alpha-fetoprotein (AFP) levels. The authors sought to determine if AFP levels can be used to modify treatment, thereby avoiding the wait for formal imaging studies and prolonged suboptimal tre...

journal_title：Pediatric hematology and oncology

authors： Sayar D,Yaniv I,Goshen Y,Cohen IJ

更新日期：2001-12-01 00:00:00

abstract：:To determine treatment outcome using ceftazidime-aminoglycosides in febrile neutropenic children with cancer, the authors conducted a prospective cohort study in 216 episodes. Early and complete responses to antibiotics were 108/216 (50.0%) and 133/216 (61.6%) episodes, respectively. Death, a modification of antibioti...

journal_title：Pediatric hematology and oncology

authors： Laoprasopwattana K,Pruekprasert P,Laosombat V,Wongchanchailert M

更新日期：2007-12-01 00:00:00

abstract：INTRODUCTION:Children with low von Willebrand factor (VWF) activity or type 1 von Willebrand disease (VWD) have increased risk of bleeding after adenotonsillar procedures and the optimal perioperative management to minimize bleeding is unknown. AIM:To report the effectiveness and safety of an institutional protocol in...

journal_title：Pediatric hematology and oncology

authors： Diaz R,Musso M,Mahoney D

更新日期：2020-08-17 00:00:00

abstract：:We evaluated serum C-reactive protein (CRP) level and serum sodium concentration as early indicators of bacteremia in neutropenic children in two different series in 1983-1984 (49 bacteremias) and 1989-1990 (29 bacteremias). During the earlier period, the goal was to avoid unnecessary antimicrobial therapy. Currently ...

journal_title：Pediatric hematology and oncology

authors： Riikonen P,Saarinen UM,Perkkiö M,Hovi L,Siimes MA

更新日期：1992-10-01 00:00:00

abstract：:Chronic granulomatous disease (CGD) is a rare genetically determined immunodeficiency. Neutrophils from CGD patients show a defective killing of phagocytosed fungi and bacteria, due not only to an impairment in oxidative burst, but also to absence of normal pH value within phagocytic vacuole following phagocytosis. Be...

journal_title：Pediatric hematology and oncology

authors： Granzotto M,Leone V,Lepore L,Zerial M,Tommasini A,Ciambra R,Gombac F,Ventura A

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Physiologic uptake of 18F-fluorodeoxyglucose (FDG) in brown adipose tissue (adipose tissue) of cancer patients may confound interpretation of positron emission tomography (PET) scans. Uptake in adipose tissue occurs in up to half of pediatric oncology patients undergoing PET scans, and is especially common in...

journal_title：Pediatric hematology and oncology

authors： George A,Sinha P,Conrad G,Memon AA,Dressler EV,Wagner LM

更新日期：2017-04-01 00:00:00

abstract：:Disaccharidases activity in the intestinal mucosa samples of rats was examined after intragastric and intramuscular methotrexate therapy. Methotrexate was given on a twice a week schedule (1 mg/kg body weight). The animals were sacrificed after 2 weeks, 1 month, and 2 months of this therapy. A statistically significan...

journal_title：Pediatric hematology and oncology

authors： Dyduch A,Steplewski Z,Koehler M,Piszka B

更新日期：1990-01-01 00:00:00

abstract：:A cooperative Italian study group on acute idiopathic thrombocytopenic purpura (AITP) has been designed to evaluate efficacy and safety of no treatment at the onset of the disease and sequential treatment with immunoglobulin and high dose steroid. One hundred thirty-eight patients with AITP entered in the trial. Eleve...

journal_title：Pediatric hematology and oncology

authors： Mori PG,Lanza T,Mancuso G,De Mattia D,Catera P,Miano C,Del Principe D,Cottafava F

更新日期：1988-01-01 00:00:00

abstract：:This study examined both the endogenous and exogenous (therapy-related) pharmacokinetics of the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) in neutropenic children with solid and systemic malignancies. The daily endogenous GM-CSF serum concentration before application was 29 pg/mL. During the 10...

journal_title：Pediatric hematology and oncology

authors： Müller CE,Mukodzi S,Reddemann H

更新日期：1999-11-01 00:00:00