Relapse of primitive mediastinal lymphoma as a myeloid mass following beam autologous transplant and subsequent refractoriness to matched unrelated umbilical cord blood allograft.

abstract：:Hemophagocytic lymphohistiocytosis (HLH) is a rare and fatal hematological syndrome that causes a disturbance of the immune system. Overall mortality of HLH is greater than 50% and the majority of patients who die do so within the first 8 weeks of chemotherapy treatment. To find clinical parameters relating to high-ri...

journal_title：Pediatric hematology and oncology

authors： Dao AT,Luong VT,Nguyen TT,Huynh QT,Phan TT,Lam MT,Ngoma AM,Koriyama C

更新日期：2014-04-01 00:00:00

abstract：:The objective of this study is to analyze the major causes of abnormal findings seen in the preoperative coagulation tests of asymptomatic pediatric patients and to discuss the usefulness of coagulation tests prior to minor surgery. Among patients who received minor surgery in Kyung Hee University Medical Center from ...

journal_title：Pediatric hematology and oncology

authors： Kang S,Yoon HS,Lee EH

更新日期：2016-05-01 00:00:00

abstract：:Brucellosis produces a variety of nonspecific hematologic abnormalities. Hematologic complications of mild anemia and leukopenia have been frequently associated with acute brucellosis, but pancytopenia is less frequently seen. In this study, records of children with brucellosis aged under or equal to 16 years, admitte...

journal_title：Pediatric hematology and oncology

authors： Akbayram S,Dogan M,Akgun C,Peker E,Parlak M,Caksen H,Oner AF

更新日期：2011-04-01 00:00:00

abstract：:To investigate the possible clinical application of the hypothesis that insufficient induction of 3,4-dihydroxyphenylalanine decarboxylase (DDC) causes accumulation and secretion of 3,4-dihydroxyphenylalanine (DOPA) in unfavorable neuroblastomas, we measured plasma DOPA in 28 neuroblastoma patients. Abnormally high le...

journal_title：Pediatric hematology and oncology

authors： Ikeda H,Suzuki N,Takahashi A,Kuroiwa M,Matsuyama S

更新日期：1996-01-01 00:00:00

abstract：:An episode of transient encephalopathy after the first course of intravenous high-dose methotrexate (HD-MTX; 1000 mg/m2) was observed in a 4-year-old girl with acute lymphoblastic leukemia. The neurological abnormalities took place 5 days after HD-MTX therapy. She experienced complex partial seizure and left hemipares...

journal_title：Pediatric hematology and oncology

authors： Kubo M,Azuma E,Arai S,Komada Y,Ito M,Sakurai M

更新日期：1992-04-01 00:00:00

abstract：:Disaccharidases activity in the intestinal mucosa samples of rats was examined after intragastric and intramuscular methotrexate therapy. Methotrexate was given on a twice a week schedule (1 mg/kg body weight). The animals were sacrificed after 2 weeks, 1 month, and 2 months of this therapy. A statistically significan...

journal_title：Pediatric hematology and oncology

authors： Dyduch A,Steplewski Z,Koehler M,Piszka B

更新日期：1990-01-01 00:00:00

abstract：:This study evaluated the effects of urokinase in the prevention of central venous catheter (CVC)-related complications in children with malignancy. Fifteen patients with 16 CVCs (study group A) received an intraluminal application of urokinase (10,000 IU in each catheter lumen for 4 h) once a week. They were monitored...

journal_title：Pediatric hematology and oncology

authors： Kalmanti M,Germanakis J,Stiakaki E,Syfridaki C,Christidou A,Tsetis D,Vardas P,Charisis G

更新日期：2002-04-01 00:00:00

abstract：:A pheochromocytoma was diagnosed in a 14-year-old boy developing hypertension after treatment with imipramine for primary nocturnal enuresis. The mechanism of action is assumed to be an inhibition of the neuronal uptake of catecholamines being released in large quantities from the tumor. The diagnosis of pheochromocyt...

journal_title：Pediatric hematology and oncology

authors： Birkebaek NH,Perrild BD

更新日期：1986-01-01 00:00:00

abstract：:A recently isolated peptide hormone, hepcidin, is thought to be the principal regulator of iron homeostasis. Hepcidin acts by limiting intestinal iron absorption and promoting iron retention in reticuloendothelial cells. Its precursor peptide form is called pro-hepcidin. The aims of this study were to determine serum ...

journal_title：Pediatric hematology and oncology

authors： Tiker F,Celik B,Tarcan A,Kilicdag H,Ozbek N,Gurakan B

更新日期：2006-06-01 00:00:00

abstract：:The aim of this study was to investigate the impact of therapy on long-term gonadal function of young people cured of childhood lymphomas and to assess whether a prepubertal state during the treatment protects the gonads from chemotherapy and/or radiotherapy late effects. Clinical evaluation, semen analysis, and endoc...

journal_title：Pediatric hematology and oncology

authors： Ben Arush MW,Solt I,Lightman A,Linn S,Kuten A

更新日期：2000-04-01 00:00:00

abstract：:Patients with thalassemia intermedia (TI) experience many complications, of which the incidence varies greatly among cases. Considering the high prevalence of thalassemia in Iran, the study was carried out to determine the frequency of TI complications in Iranian patients and to find possible risk factors for each of ...

journal_title：Pediatric hematology and oncology

authors： Rafsanjani KA,Mafi N,Tafreshi RI

更新日期：2011-09-01 00:00:00

abstract：:A cooperative Italian study group on acute idiopathic thrombocytopenic purpura (AITP) has been designed to evaluate efficacy and safety of no treatment at the onset of the disease and sequential treatment with immunoglobulin and high dose steroid. One hundred thirty-eight patients with AITP entered in the trial. Eleve...

journal_title：Pediatric hematology and oncology

authors： Mori PG,Lanza T,Mancuso G,De Mattia D,Catera P,Miano C,Del Principe D,Cottafava F

更新日期：1988-01-01 00:00:00

abstract：:The FLT3 gene encodes a tyrosine kinase receptor that regulates proliferation and differentiation of hematopoietic cells. Recently, the internal duplication of FLT3 has been observed in hematological malignancies, suggesting the involvement of these mutations in leukemogenesis. The authors analyzed the expression of F...

journal_title：Pediatric hematology and oncology

authors： Ishii E,Zaitsu M,Ihara K,Hara T,Miyazaki S

更新日期：1999-09-01 00:00:00

abstract：:High doses of intravenous deferoxamine via central venous line (CVL) has recently been shown to improve survival in patients with noncompliant thalassemia major (TM). The aim of this retrospective study was to evaluate the extent of CVL-related thrombosis and to determine the presence of prothrombotic factors in child...

journal_title：Pediatric hematology and oncology

authors： Finkelstein Y,Yaniv I,Berant M,Zilber R,Garty BZ,Epstein O,Lahav J,Tamary H

更新日期：2004-07-01 00:00:00

abstract：:This study investigated the influence of levamisole therapy on immunocompetent cells and lymphocyte reactivity to mitogens in 25 children with brain tumor. Eleven (11/25) patients were receiving chemotherapy and immunomodulating drug levamisole 3 months after neurosurgery, during maintenance chemotherapy, 2.5 mg/kg of...

journal_title：Pediatric hematology and oncology

authors： Hajnzić TF,Kastelan M,Lukac J,Hajnzić T

更新日期：1999-07-01 00:00:00

abstract：:A prospective, open-label, randomized, comparative study in pediatric cancer patients was conducted to evaluate the efficacy and safety of cefepime and meropenem in the empiric therapy of febrile neutropenic patients. Febrile episodes were classified as microbiologically documented infection, clinical documented infec...

journal_title：Pediatric hematology and oncology

authors： Oguz A,Karadeniz C,Citak EC,Cil V,Eldes N

更新日期：2006-04-01 00:00:00

abstract：:It is well known in the literature that cancer creates educationally related barriers for all children, which may or may not contribute to clinically relevant school problems. The goal of this study was to obtain a base rate for the characteristic pattern of school functioning for children with leukemia, so that the c...

journal_title：Pediatric hematology and oncology

authors： Adamoli L,Deasy-Spinetta P,Corbetta A,Jankovic M,Lia R,Locati A,Fraschini D,Masera G,Spinetta JJ

更新日期：1997-03-01 00:00:00

abstract：:The authors describe a 10-year-old boy with beta-thalassemia major who received double-unit unrelated cord blood transplantation and had a rocky post-transplantation course that included an episode of massive pericardial effusion. Pericardial tube drainage was performed for evacuating fluid. Results showed hemorrhagic...

journal_title：Pediatric hematology and oncology

authors： Chung HT,Hsieh TC,Yu MC,Chang YS,Lo WC,Jaing TH

更新日期：2007-06-01 00:00:00

abstract：:This study examined both the endogenous and exogenous (therapy-related) pharmacokinetics of the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) in neutropenic children with solid and systemic malignancies. The daily endogenous GM-CSF serum concentration before application was 29 pg/mL. During the 10...

journal_title：Pediatric hematology and oncology

authors： Müller CE,Mukodzi S,Reddemann H

更新日期：1999-11-01 00:00:00

abstract：:Focal nodular hyperplasia (FNH) of the liver is rare in children, and it is usually diagnosed through a biopsy of the liver or hepatectomy. The authors report a case of a 10-year-old girl with multiple focal nodular hyperplasia lesions of the liver after the completion of tumor therapy for advanced neuroblastoma, and ...

journal_title：Pediatric hematology and oncology

authors： Sugito K,Kusafuka T,Kawashima H,Uekusa S,Furuya T,Ohashi K,Inoue M,Ikeda T,Koshinaga T,Maebayashi T

更新日期：2010-04-01 00:00:00

abstract：:This study evaluated the efficacy of hydroxyurea treatment in the prevention of vaso-occlusive crises among children and teenagers with severe sickle cell anemia and sickle cell beta-thalassemia. Nineteen children and young adults with severe sickle cell disease were enrolled to the hydroxyurea treatment trial. The in...

journal_title：Pediatric hematology and oncology

authors： Koren A,Segal-Kupershmit D,Zalman L,Levin C,Abu Hana M,Palmor H,Luder A,Attias D

更新日期：1999-05-01 00:00:00

abstract：:Anaplastic lymphoma kinase (ALK) inhibitors such as crizotinib and alectinib have been shown to have significant activity in ALK-rearranged non-small cell lung cancers (NSCLC). There are no data for alectinib's safety or efficacy in younger patients, though it is superior to crizotinib in adult trials. We present a 14...

journal_title：Pediatric hematology and oncology

authors： Balzer BWR,Loo C,Wegner EA,Nath CE,Lee S,Smith C,Lewis CR,Trahair TN,Anazodo AC

更新日期：2018-01-01 00:00:00

abstract：:Unexplained menorrhagia and hematuria occurred in a 13-year-old female with a mild inherited platelet disorder who had never experienced prior bleeding as a result of this disorder. An intensive search revealed that this patient was receiving coumadin that was given by the mother. In addition, the mother drew large vo...

journal_title：Pediatric hematology and oncology

authors： Souid AK,Korins K,Keith D,Dubansky S,Sadowitz PD

更新日期：1993-07-01 00:00:00

abstract：:Although survival rates in childhood cancer have distinctly improved, pediatric cancer patients often experience various disease- and treatment-related side effects with long-term consequences. Despite current studies investigating inactivity and limitations in physical functioning and quality of life in pediatric can...

journal_title：Pediatric hematology and oncology

authors： Beulertz J,Bloch W,Prokop A,Baumann FT

更新日期：2013-05-01 00:00:00

abstract：:Acute basophilic leukemia is a distinct entity of Acute Myeloid Leukemia (AML) with primary differentiation to basophils. Increased basophil count has been described in AML cases with translocation t(6;9)(p23;q34) or other chromosomal abnormalities. We describe a 15-year old female teenager with AML and excess periphe...

journal_title：Pediatric hematology and oncology

authors： Servitzoglou M,Grenzelia M,Baka M,Harisi M,Pourtsidis A,Bouhoutsou D,Varvoutsi M,Doganis D,Dana H,Divane A,Kosmidis H

更新日期：2014-03-01 00:00:00

abstract：:Both transplanted and leukemia patients are at high risk (HR) for invasive pulmonary aspergillosis (IPA). Methods for rapid diagnosis are crucial. Our objective was to investigate the impact of serial serum galactomannan assay (GMA) screening on IPA diagnosis in children. Between January 2010 and December 2011, all ch...

journal_title：Pediatric hematology and oncology

authors： Gefen A,Zaidman I,Shachor-Meyouhas Y,Avidor I,Hakim F,Weyl Ben-Arush M,Kassis I

更新日期：2015-03-01 00:00:00

abstract：:Maternal education might be an important factor for the neuroblastoma risk in children, but it was conflicting. This meta-analysis was performed to evaluate the relationship between maternal education and neuroblastoma susceptibility and to explore whether maternal education was an important indicator to be associated...

journal_title：Pediatric hematology and oncology

authors： Wang P,Liao N,Liao XH,Liang B,Huang CX,Li W

更新日期：2013-02-01 00:00:00

abstract：:Bloodstream infections (BSI) represent one of the most serious complications in patients in the hematology-oncology unit. In this study, the prevalence, distribution, drug sensitivity profiles, and clinical outcome of BSI were analyzed in pediatric patients with hematological malignancies. Patients admitted to the ped...

journal_title：Pediatric hematology and oncology

authors： Chen S,Liu S,Yuan X,Mai H,Lin J,Wen F

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Alterations in the tumor suppressor gene TP53 have been associated with poor outcome in adult hematological malignancies. We have earlier reported an increased expression of the TP53 encoded protein p53, in bone marrow samples from pediatric patients with aggressive leukemia. Our aim was now to evaluate p53 ...

journal_title：Pediatric hematology and oncology

authors： Honkaniemi E,Mattsson K,Barbany G,Sander B,Gustafsson B

更新日期：2014-05-01 00:00:00

abstract：:Ondansetron (Zofron, Glaxo) and tropisetron (Navoban, Sandoz) are selective serotonin (5HT3) antagonists that have proven very effective in the prevention of vomiting and nausea in adults and children receiving cancer chemotherapy. This study compared the efficacy of the two agents in the prevention of vomiting and na...

journal_title：Pediatric hematology and oncology

authors： Stiakaki E,Savvas S,Lydaki E,Bolonaki I,Kouvidi E,Dimitriou H,Kambourakis A,Kalmanti M

更新日期：1999-03-01 00:00:00