Bioinformatics assistance of metabolic and nutrition management in the ICU.

abstract：PURPOSE OF REVIEW:The main aim of this review is to summarize current knowledge of tumor protein p53-inducible nuclear protein 2 (TP53INP2) function and its role in skeletal muscle proteostasis. RECENT FINDINGS:Autophagy is directly involved in the regulation of skeletal muscle mass. Thus, excessive autophagy is assoc...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sala D,Zorzano A

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Occlusions of central venous catheters in service are frequent, but the random nature of the problem has resulted in a piecemeal approach to solving it. The purpose of this review is to examine what is known from past and recent publications and to recommend strategies for future investigations. RECE...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hardy G,Ball P

更新日期：2005-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this overview is to highlight the multiple ways in which oxidative stress could be exacerbating muscle wasting. Understanding these interactions in vivo will assist in identifying opportunities for more targeted therapies to reduce skeletal muscle wasting. RECENT FINDINGS:There are many ex...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Arthur PG,Grounds MD,Shavlakadze T

更新日期：2008-07-01 00:00:00

abstract：:Lipids play an extraordinary range of roles in normal and deranged metabolism. In diabetes and obesity, lipids have often been seen just as impacting on the energy balance equation. New data are extending our understanding of how lipid subclasses influence carbohydrate and lipid metabolism at multiple control points: ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Storlien LH,Hulbert AJ,Else PL

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the interest of functional food in low-income countries by analyzing various necessary factors. RECENT FINDINGS:Being on a low income would appear to relate most often to an unbalanced diet, both qualitatively and quantitatively, which may be damaging to health in the long term. Most ch...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Das A,Chakraborty R

更新日期：2014-11-01 00:00:00

abstract：:The nuclear factor kappa B family of inducible transcription factors regulates the expression of many genes. Nuclear factor kappa B has been implicated in autoimmune and inflammatory diseases, infection, cell survival, and cell transformation with subsequent promotion of cancer. In this review, we summarize features o...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Holmes-McNary M

更新日期：2002-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review summarizes recent evolutions in knowledge and discusses the concept of whom and when parenteral nutrition should be considered in critically ill patients as a total form of nutrition, in a supplemental form, or never. RECENT FINDINGS:Recent developments in our understanding of the ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ridley EJ

更新日期：2020-12-10 00:00:00

abstract：PURPOSE OF REVIEW:A fundamental advance in our understanding of endocrine control of energy balance and body weight came with the discovery of the adipocyte-derived hormone leptin. The leptin pathway appeared to be the long-sought peripheral signal pathway from the adipose tissue to the brain involved in the regulation...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hukshorn CJ,Saris WH

更新日期：2004-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition is prevalent in critically ill patients and is linked to worse outcomes such as prolonged mechanical ventilation, length of intensive care unit (ICU) stay, and increased mortality. Therefore, nutritional therapy is important. However, it is often difficult to accurately identify those at ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dong V,Karvellas CJ

更新日期：2020-12-05 00:00:00

abstract：PURPOSE OF REVIEW:In this review methods to measure the content and distribution of body fat or adipose tissue in humans are examined. The review particularly emphasizes methods to characterize regional fat distribution and ectopic fat (fat contained within other tissues) including specific applications and implication...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Goodpaster BH

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the evidences for and against the different nutritional and nonnutritional therapeutic approaches for severe alcoholic steatohepatitis, based on data from randomized controlled trials, in order to answer the question posed in the title: 'more of the same or something new?'. RECENT FINDING...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Cabré E

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Here, we discuss recent work focused on the role of activating transcription factor 4 (ATF4) in skeletal muscle atrophy. RECENT FINDINGS:Muscle atrophy involves and requires widespread changes in skeletal muscle gene expression; however, the transcriptional regulatory proteins responsible for those c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Adams CM,Ebert SM,Dyle MC

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin K is an enzyme cofactor for the carboxylation of vitamin K-dependent proteins. Functions include coagulation and regulation of calcification. Different clinical conditions may alter vitamin K requirements by affecting vitamin K status and vitamin K-dependent proteins carboxylation that are rev...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Harshman SG,Saltzman E,Booth SL

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, the latest evidence on the influence of dietary protein and plasma amino acids in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) is discussed. RECENT FINDINGS:Increasing protein consumption during weight loss and maintenance may help reduce liver fat content. Conversely,...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Tricò D,Biancalana E,Solini A

更新日期：2021-01-01 00:00:00

abstract：:The most common methods for measuring the incorporation of tracer amino acids into tissue protein are the constant tracer infusion and the flooding dose. The flooding dose is an attractive method for measuring tissue protein synthesis because of its convenience and precision. A primary assumption of the method, that t...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Davis TA,Reeds PJ

更新日期：2001-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this study was to highlight recent evidence on protein requirement and physical activity recommendations in older adults and their interrelationship. RECENT FINDINGS:Higher protein intake in older adults is beneficial for better physical function, reduced fracture risk, healthy ageing and ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Yeung SSY,Chan RSM,Woo J

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Congestive heart failure is increasing in prevalence and represents a major public health problem. The syndrome of advanced heart failure often includes muscle wasting, commonly termed cardiac cachexia, which is a predictor of poor outcome. Mechanisms of cardiac cachexia are poorly understood, but the...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Delafontaine P,Akao M

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:High-fat diets lead to obesity and increase the risk of developing insulin resistance and type 2 diabetes. Adipose tissue and skeletal muscle act as endocrine organs, and produce various cytokines that can potentially alter peripheral insulin sensitivity. The purpose of the present review is to briefl...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Stefanyk LE,Dyck DJ

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Oxidative stress plays a central role in the transition from simple steatosis to nonalcoholic steatohepatitis (NASH). An effective therapeutic strategy is to target reduction in oxidative stress in NASH patients. The aim of this review is to discuss the role of oxidative stress in NASH and biological ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Pacana T,Sanyal AJ

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to examine the concept of anorexia of aging, including its complex pathophysiology and the multifaceted interventions required to prevent adverse health consequences from this geriatric syndrome. RECENT FINDINGS:Anorexia of aging is extremely common, occurring in up to 3...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sanford AM

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This review depicts recent developments concerning the role of the liver in control of carbohydrate and lipid utilization from ingestion to storage; it covers the liver's influence on food intake, post-absorptive nutrient metabolism and body weight. The mechanisms involved have implications for the pa...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Langhans W

更新日期：2003-07-01 00:00:00

abstract：:Catabolism of fat-free mass affects both the quality of life and survival of patients. Because of variations in fluid status during acute illness, changes in body weight are difficult to evaluate and interpret during treatment. Nutritional assessment should therefore evaluate fat-free and fat mass changes during metab...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kyle UG,Pichard C

更新日期：2000-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle is gaining increased attention as an endocrine organ. Recently, novel myokines and new effects of already established myokines have been identified. The objective of this review is to give an update on the recent advances in the field. RECENT FINDINGS:Several hundred putative myokines...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Karstoft K,Pedersen BK

更新日期：2016-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This article is intended to briefly overview available methodological approaches for the study of regional metabolism in man in vivo, and to summarize recent advances in this field of research. RECENT FINDINGS:Several methods have been developed and currently allow for the qualitative and quantitativ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Magkos F,Sidossis LS

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to emphasize the importance of malnutrition in frail institutionalized elderly and discuss recent interventions that have been shown to decrease its prevalence. RECENT FINDINGS:A Medline search was conducted from 1968 to 2007 under the search terms aging, nutrition, and nur...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Labossiere R,Bernard MA

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine the results of new investigations that look at the efficacy of nutrient/training strategies on metabolism and athletic performance. RECENT FINDINGS:'Dietary periodization' involves the manipulation of macronutrient intake in association with changes in physical training. Such interventions...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Burke LM,Hawley JA

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Metabolic syndrome (MetS) is associated with increased risk of obesity, type 2 diabetes mellitus and cardiovascular diseases. MetS prevalence has been associated with diet inadequacy. Conversely, the cumulative incidence of MetS has been inversely associated with a Mediterranean-style diet that includ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Goncalves A,Amiot MJ

更新日期：2017-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Preventing unintentional weight and muscle loss is of crucial importance to maintain the condition and well-being of patients with cancer, improve treatment response and tolerance, and prolong survival. Anabolic resistance might explain why some cancer patients do not respond to nutritional interventi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Engelen MP,van der Meij BS,Deutz NE

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Leucine does not only serve as a substrate for protein synthesis but is also recognized as a potent signal nutrient that regulates protein metabolism. Accordingly, leucine supplementation has been suggested to develop muscle mass or prevent protein loss in several conditions characterized by muscle pr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Balage M,Dardevet D

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The role of calorie restriction in humans is controversial. Recently, new data in monkeys and humans have provided new insights into the potential role of calorie restriction in longevity. RECENT FINDINGS:A study in rhesus monkeys showed a reduction in aging-associated mortality. A number of controll...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Morley JE,Chahla E,Alkaade S

更新日期：2010-01-01 00:00:00