Contrast processing by ON and OFF bipolar cells.

abstract：:Inhibitory synaptic transmission via GABA and glycine receptors plays a crucial role in shaping the excitatory response of neurons in the retina. Whole-cell recordings were obtained from ganglion cells in the intact rabbit eyecup preparation to correlate GABA- and glycine-activated currents with the presence of their ...

journal_title：Visual neuroscience

authors： Rotolo TC,Dacheux RF

更新日期：2003-05-01 00:00:00

abstract：:The aim of this study was to determine whether agmatine, a channel permeable probe, can identify photoreceptor dysfunction in the Royal College of Surgeons (RCS) retina at an earlier stage to that shown by apoptosis or anatomical markers, and also characterize the neurochemical development of the inner retina in the n...

journal_title：Visual neuroscience

authors： Kalloniatis M,Tomisich G,Wellard JW,Foster LE

更新日期：2002-01-01 00:00:00

abstract：:Human, macaque monkey, and rat retinas were immunostained with a polyclonal antibody preparation against purified recoverin, a 23-kD calcium-binding protein isolated from bovine retina that localizes to rods and cones (Dizhoor et al., 1991). In addition to immunoreactive photoreceptors, we have identified subpopulatio...

journal_title：Visual neuroscience

authors： Milam AH,Dacey DM,Dizhoor AM

更新日期：1993-01-01 00:00:00

abstract：:Many diverse retinal disorders are characterized by retinal edema; yet, little experimental attention has been given to understanding the fundamental mechanisms underlying and contributing to these fluid-based disorders. Water transport in and out of cells is achieved by specialized membrane channels, with most rapid ...

journal_title：Visual neuroscience

authors： Goodyear MJ,Crewther SG,Junghans BM

更新日期：2009-03-01 00:00:00

abstract：:One striking transformation in response properties that occurs in the geniculo-cortical pathway is the appearance of a high degree of orientation selectivity in the cortex. This property may be conceived as arising purely from the excitatory inputs to the cell, as being structured largely by the inhibition a cortical ...

journal_title：Visual neuroscience

authors： Volgushev M,Pei X,Vidyasagar TR,Creutzfeldt OD

更新日期：1993-11-01 00:00:00

abstract：:Dopaminergic interplexiform cells in the retina of the blue acara were investigated using an antiserum against tyrosine hydroxylase and PAP visualization. In whole-mount preparations, we observed a homogeneous distribution of cell bodies throughout the retina without any indication of regional specialization. At the f...

journal_title：Visual neuroscience

authors： Wagner HJ,Wulle I

更新日期：1992-09-01 00:00:00

abstract：:Agrin is a large extracellular matrix protein that directs the accumulation of acetylcholine receptors at the neuromuscular junction. Recent evidence suggests that agrin may be involved in organizing synapses in the visual system as well. Focussing on the pathway that controls accommodation and pupilloconstriction, th...

journal_title：Visual neuroscience

authors： McAvoy M,Smith MA,Fujii JT

更新日期：1996-03-01 00:00:00

abstract：:Adult teleost fish retinas can regenerate neurons following either surgical or pharmacological injury. The cellular milieu of the damaged retina within which regenerated neurons are produced might be different in these two model systems of retinal injury, and thus the phenotypic attributes of regenerated neurons in th...

journal_title：Visual neuroscience

authors： Cameron DA,Powers MK

更新日期：2000-07-01 00:00:00

abstract：:Retinae of the crab Leptograpsus which had been maintained on a 12-h light/12-h dark cycle were cultured in vitro and exposed to 1 microM okadaic acid (OKA) at 0.75 h before light onset. Control retinae were subjected to the same routine and sampled at the same times without OKA treatment. At the concentration used, O...

journal_title：Visual neuroscience

authors： Blest AD,Carter M,Clausen JA,Stowe S,Trowell SC,Tsukitani Y

更新日期：1991-07-01 00:00:00

abstract：:As a part of ongoing efforts to understand the cholinergic circuitry in the mammalian retina, we studied the coexpression of nicotinic acetylcholine receptors (nAChRs) and gamma-aminobutyric acid (GABA), the GABA transporter 1 (GAT-1), or choline acetyltransferase (ChAT) immunoreactivity in the rabbit retina. Double-l...

journal_title：Visual neuroscience

authors： Dmitrieva NA,Lindstrom JM,Keyser KT

更新日期：2001-01-01 00:00:00

abstract：:The activity of the endogenous retinal dopamine (DA) pathway has been examined in the pigmented rat using retinas obtained from normal adult (approximately 3 months) and senile adults (approximately 24 months) using an in vitro electrophysiological approach. By comparing the pharmacological sensitivity of the horizont...

journal_title：Visual neuroscience

authors： Hankins MW

更新日期：2000-11-01 00:00:00

abstract：:Increment threshold functions of the electroretinogram (ERG) b-wave were obtained from goldfish using an in vivo preparation to study intraretinal mechanisms underlying the increase in perceived brightness induced by depletion of retinal dopamine by 6-hydroxydopamine (6-OHDA). Goldfish received unilateral intraocular ...

journal_title：Visual neuroscience

authors： Lin ZS,Yazulla S

更新日期：1994-07-01 00:00:00

abstract：:Electroretinogram (ERG) responses of the cone system to a flickering stimulus can exhibit a cyclic variation in amplitude. This phenomenon of synchronous period doubling has been attributed to a nonlinear feedback mechanism within the retina that alters response gain. The aim of the present study was to investigate in...

journal_title：Visual neuroscience

authors： Alexander KR,Levine MW,Super BJ

更新日期：2005-11-01 00:00:00

abstract：:The large receptive fields of retinal horizontal cells are thought to reflect extensive electrical coupling via gap junctions. It was shown recently that the biotinylated tracers, biocytin and Neurobiotin, provide remarkable images of coupling between many types of retinal neuron, including horizontal cells. Further, ...

journal_title：Visual neuroscience

authors： Bloomfield SA,Xin D,Persky SE

更新日期：1995-09-01 00:00:00

abstract：:The Tennessee Mouse Genome Consortium (TMGC) is in its fifth year of a ethylnitrosourea (ENU)-based mutagenesis screen to detect recessive mutations that affect the eye and brain. Each pedigree is tested by various phenotyping domains including the eye, neurohistology, behavior, aging, ethanol, drug, social behavior, ...

journal_title：Visual neuroscience

authors： Jablonski MM,Wang X,Lu L,Miller DR,Rinchik EM,Williams RW,Goldowitz D

更新日期：2005-09-01 00:00:00

abstract：:To gain insight into how vision guides eye movements, monkeys were trained to make a single saccade to a specified target stimulus during feature and conjunction search with stimuli discriminated by color and shape. Monkeys performed both tasks at levels well above chance. The latencies of saccades to the target in co...

journal_title：Visual neuroscience

authors： Bichot NP,Schall JD

更新日期：1999-01-01 00:00:00

abstract：:Lateral suprasylvian visual cortex in the cat has been studied extensively, but its retinotopic organization remains controversial. Although some investigators have divided this region into many distinct areas, others have argued for a simpler organization. A clear understanding of the region's retinotopic organizatio...

journal_title：Visual neuroscience

authors： Sherk H,Mulligan KA

更新日期：1993-01-01 00:00:00

abstract：:The sudden displacement of the retinal image during a saccade raises the visual threshold of human observers to foveal stimuli. The fall in visual sensitivity observed during this phenomenon, known as saccadic suppression, seems to occur very early in the visual processing chain. The lateral geniculate nucleus (LGN) i...

journal_title：Visual neuroscience

authors： Derrington AM,Felisberti F

更新日期：1998-09-01 00:00:00

abstract：:To explore the possible influence of defined genetic backgrounds on photoreceptor viability and function in mice carrying a targeted disruption of the rhodopsin gene, the severities of retinopathies in Rho-/- mice on C57BL/6J and 129Sv congenic backgrounds were compared by light microscopy and electroretinography and ...

journal_title：Visual neuroscience

authors： Humphries MM,Kiang S,McNally N,Donovan MA,Sieving PA,Bush RA,Machida S,Cotter T,Hobson A,Farrar J,Humphries P,Kenna P

更新日期：2001-05-01 00:00:00

abstract：:We investigated whether regenerating mature axons recapitulate embryonic features essential to successful reconnectivity within the injured nervous system. Strips from embryonic and adult chick retinae were cultured, and outgrowing axons were examined morphometrically and immunohistochemically. In addition, the target...

journal_title：Visual neuroscience

authors： Vanselow J,Müller B,Thanos S

更新日期：1991-06-01 00:00:00

abstract：:We examined achromatic contrast discrimination in asymptomatic carriers of 11778 Leber's hereditary optic neuropathy (LHON 18 controls) and 18 age-match were also tested. To evaluate magnocellular (MC) and Parvocellular (PC) contrast discrimination, we used a version of Pokorny and Smith's (1997) pulsed/steady-pedesta...

journal_title：Visual neuroscience

authors： Gualtieri M,Bandeira M,Hamer RD,Costa MF,Oliveira AG,Moura AL,Sadun F,De Negri AM,Berezovsky A,Salomão SR,Carelli V,Sadun AA,Ventura DF

更新日期：2008-05-01 00:00:00

abstract：:Arrestins participate in the termination of phototransduction in both vertebrates and invertebrates. However, the visual arrestins of invertebrates and vertebrates differ significantly from one another in that the invertebrate visual arrestins become phosphorylated rapidly in response to light while those in the photo...

journal_title：Visual neuroscience

authors： Battelle BA,Andrews AW,Kempler KE,Edwards SC,Smith WC

更新日期：2000-09-01 00:00:00

abstract：:In order to elucidate the role of putative indoleaminergic amacrine cells in visual processing, we have employed pharmacological agents specific for the two classes of serotonin receptor, 5-HT2 and 5-HT1, which have been identified in both the retina and brain. Perfusion of the rabbit retina with 5-HT2 selective antag...

journal_title：Visual neuroscience

authors： Brunken WJ,Daw NW

更新日期：1988-01-01 00:00:00

abstract：:Recent work has revealed multiple pathways for cross-orientation suppression in cat and human vision. In particular, ipsiocular and interocular pathways appear to assert their influence before binocular summation in human but have different (1) spatial tuning, (2) temporal dependencies, and (3) adaptation after-effect...

journal_title：Visual neuroscience

authors： Meese TS,Challinor KL,Summers RJ

更新日期：2008-07-01 00:00:00

abstract：:L and M cones, divided into two groups by absorption spectra, have not been distinguished by structure. Here, we report what may be such a difference. We reconstructed the synaptic terminals of 16 non-S cones and the dendritic arbors of their ON and OFF midget bipolar cells from high-magnification electron micrographs...

journal_title：Visual neuroscience

authors： Schein S,Ngo IT,Huang TM,Klug K,Sterling P,Herr S

更新日期：2011-01-01 00:00:00

abstract：:Rod and cone photoresponses in a variety of species have been accurately described with linear multistage filter models. In this study, the response latency and initial coding of intensity at two higher levels of visual processing are related to such photoreceptor responses. One level is the retinal output (spiking di...

journal_title：Visual neuroscience

authors： Donner K

更新日期：1989-07-01 00:00:00

abstract：:Lesion or inactivation of the superior colliculus (SC) of the cat results in an animal that fails to orient toward peripheral visual stimuli which normally evoke a brisk, reflexive orienting response. A failure to orient toward a visual stimulus could be the result of a sensory impairment (a failure to detect the visu...

journal_title：Visual neuroscience

authors： Fitzmaurice MC,Ciaramitaro VM,Palmer LA,Rosenquist AC

更新日期：2003-11-01 00:00:00

abstract：:Eye growth and refraction are regulated by visual processing in the retina. Until now, the messengers released by the retina to induce these changes are largely unknown. Previously, it was found that glucagon amacrine cells respond to defocus in the retinal image and even to its sign. The expression of the immediate-e...

journal_title：Visual neuroscience

authors： Feldkaemper MP,Schaeffel F

更新日期：2002-11-01 00:00:00

abstract：:In previous work, we have shown that sudden image displacements well outside the classical receptive field modulate the visual sensitivity of LGN relay cells. Here we report the effect of image displacements on the response versus contrast function. The stimuli consisted of a central spot of optimal size and polarity ...

journal_title：Visual neuroscience

authors： Felisberti F,Derrington AM

更新日期：1999-09-01 00:00:00

abstract：:Mechanisms that mediate the calcium influx in mammalian horizontal cells were studied. Horizontal cells (HCs) enzymatically dissociated from the rabbit retina were recorded by the whole-cell configuration of the patch-clamp technique and by calcium image ratioespectrophotometry of Fura-2 loaded cells. AMPA-preferring ...

journal_title：Visual neuroscience

authors： Rivera L,Blanco R,de la Villa P

更新日期：2001-11-01 00:00:00