Lung function after total intravenous anaesthesia or balanced anaesthesia with sevoflurane.

abstract：:To understand the cellular and molecular basis of the anaesthetic state, it is important to remember that, in the intact CNS, synapses operate within elaborate nerve networks. From the data presented above, it is evident that block of impulse conduction in presynaptic fibres does not explain the effects of most anesth...

journal_title：British journal of anaesthesia

authors： Pocock G,Richards CD

更新日期：1993-07-01 00:00:00

abstract：:Clinicians inevitably encounter patients who meet the diagnostic criteria for the metabolic syndrome (MetS); these criteria include central obesity, hypertension, atherogenic dyslipidaemia, and hyperglycaemia. Regardless of the variations in its definition, MetS may be associated with adverse outcomes in patients unde...

journal_title：British journal of anaesthesia

authors： Tzimas P,Petrou A,Laou E,Milionis H,Mikhailidis DP,Papadopoulos G

更新日期：2015-08-01 00:00:00

abstract：:In rats injected s.c. with formalin, behavioural correlates of the amount and pattern of Fos-like immunoreactivity (Fos-Ll) (molecular responses to pain) were studied to test if early phase treatment with 75% nitrous oxide or 2% halothane, or both, suppressed subsequent spinal sensitization. Rats were allocated to fou...

journal_title：British journal of anaesthesia

authors： Sun WZ,Shyu BC,Shieh JY

更新日期：1996-01-01 00:00:00

abstract：:We tested the hypothesis that the solvent for etomidate was a factor in the incidence of pain and other side effects after injection, and that these were associated with histamine release. Nine of 10 volunteers who received etomidate in a propylene glycol formulation reported moderate to severe pain on injection; only...

journal_title：British journal of anaesthesia

authors： Doenicke AW,Roizen MF,Hoernecke R,Lorenz W,Ostwald P

更新日期：1999-09-01 00:00:00

abstract：:The induction dose requirements of propofol were compared in three age groups in 300 unpremedicated healthy Chinese children: group A, younger than 2 yr (n = 48); group B, 2-5 yr (n = 117); group C, 6-12 yr (n = 135). Patients in each group were allocated randomly to receive one of eight doses of propofol (1.2, 1.4, 1...

journal_title：British journal of anaesthesia

authors： Aun CS,Short SM,Leung DH,Oh TE

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:In this randomized, double-blind study, the effects of thoracic and lumbar epidural anaesthesia on the induction doses (IDs) and maintenance doses (MDs) of propofol during bispectral index (BIS) guided total i.v. anaesthesia were compared. METHODS:Fifty-four patients (three groups, n=18 each) undergoing uro...

journal_title：British journal of anaesthesia

authors： Sentürk M,Güçyetmez B,Ozkan-Seyhan T,Karadeniz M,Dinçer S,Akpir D,Sengül T,Denkel T

更新日期：2008-08-01 00:00:00

abstract：:Methylene blue-treated fresh-frozen plasma (MB-FFP) is mainly used in Europe. The advantage of the methylene blue system is that units can be treated individually. The combined action of methylene blue and illumination is a photodynamic process preventing viral RNA and DNA replication. We report the first immediate al...

journal_title：British journal of anaesthesia

authors： Dewachter P,Castro S,Nicaise-Roland P,Chollet-Martin S,Le Beller C,Lillo-le-Louet A,Mouton-Faivre C

更新日期：2011-05-01 00:00:00

abstract：:The new emulsion formulation of di-isopropyl phenol (propofol) was compared with methohexitone and thiopentone for induction of anaesthesia in day cases. Propofol produced significantly smoother induction of anaesthesia, but caused more cardiovascular and respiratory depression. Pain on injection was significantly les...

journal_title：British journal of anaesthesia

authors： Mackenzie N,Grant IS

更新日期：1985-08-01 00:00:00

abstract：:The accuracy of five new oxygen and nitrous oxide flowmeter units was investigated using the bubble meter method. The results were compared with those previously found in flowmeters withdrawn from clinical use. New oxygen flowmeters demonstrated less inaccuracies than old flowmeters. No differences were found between ...

journal_title：British journal of anaesthesia

authors： Waaben J,Brinkløv MM,Stokke DB

更新日期：1980-01-01 00:00:00

abstract：:Isolated, cultured rat pancreatic islets of Langerhans were incubated in medium containing glucose 2 or 20 mmol litre-1 and with glucose supplemented with midazolam 10, 100 or 1000 ng ml-1. Glucose 20 mmol litre-1 with the addition of noradrenaline 10 mumol litre-1 was used as a control. In contrast with noradrenaline...

journal_title：British journal of anaesthesia

authors： Desborough JP,Jones PM,Persaud SJ,Howell SL

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:We developed a new neuromuscular transmission monitor, the compressomyograph (CMG, European patent number: EP 06018557.6, US patent number: US 60/824.541). This is the first preliminary report comparing neuromuscular block monitored by CMG and the Relaxometer mechanomyograph (MMG). METHODS:The two monitors ...

journal_title：British journal of anaesthesia

authors： Dahaba AA,Bornemann H,Holst B,Wilfinger G,Metzler H

更新日期：2008-03-01 00:00:00

abstract：:Plasma diazepam concentrations were determined following oral, i.m. and i.v. administration to a group of pregnant women with pre-eclampsia and a group of normal pregnant women. Diazepam concentrations were greater following oral as compared with i.m. administration in the control group, who received a single 5-mg dos...

journal_title：British journal of anaesthesia

authors： Sturdee DW

更新日期：1976-11-01 00:00:00

abstract：:A simple method of adapting a pressure-cycled ventilator of the flow generator type to ventilate patients on a circle-absorber anaesthetic system is described. Standard lengths of corrugated black rubber tubing are placed between the ventilator and the circle-absorber is deadspace, replacing the reservoir bag. The per...

journal_title：British journal of anaesthesia

authors： Jeal DE

更新日期：1977-03-01 00:00:00

abstract：:The metabolic effect of infusing 1.0-1.5 litre of Hartmann's solution to normal subjects and those with maturity onset diabetes has been studied during surgery. It was found that the use of Hartmann's solution after operation was associated with a 7.5 mmol litre-u increase in plasm glucose concentration compared with ...

journal_title：British journal of anaesthesia

authors： Thomas DJ,Alberti KG

更新日期：1978-02-01 00:00:00

abstract：:Spinal anaesthesia is the preferred anaesthetic technique for elective Caesarean deliveries. Hypotension is the most common side-effect and has both maternal and neonatal consequences. Different strategies have been attempted to prevent spinal-induced hypotension, including the use of low-dose bupivacaine. We conducte...

journal_title：British journal of anaesthesia

authors： Arzola C,Wieczorek PM

更新日期：2011-09-01 00:00:00

abstract：:Following a paravertebral surgical incision, mature, female rats under ether anaesthesia were exposed to either 3% nitrous oxide, continuously for 48 h, or 50% nitrous oxide, 4 h each day for 7 days. For each exposure group, a similar number of rats was exposed to atmospheres containing no nitrous oxide. Wound healing...

journal_title：British journal of anaesthesia

authors： Algie TA,Seth A,Barbenel JC,Galloway DJ,Gray WM,Spence AA

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:Fresh-frozen plasma (FFP) is widely used in critically ill patients, despite a weak evidence base. Factors that influence the decision to transfuse FFP before intravascular catheter insertion are poorly described. METHODS:We undertook a case-controlled study based on a prospective cohort study of 1923 admis...

journal_title：British journal of anaesthesia

authors： Hall DP,Lone NI,Watson DM,Stanworth SJ,Walsh TS,Intensive Care Study of Coagulopathy (ISOC) Investigators.

更新日期：2012-12-01 00:00:00

abstract：:Fentanyl or alfentanil, in doses approximating to those used in clinical practice, was added to the priming fluid of an extracorporeal circuit before the institution of cardiopulmonary bypass (CPB). The concentrations of both drugs in the priming fluid were measured over a 20-min period. The concentration of fentanyl ...

journal_title：British journal of anaesthesia

authors： Skacel M,Knott C,Reynolds F,Aps C

更新日期：1986-09-01 00:00:00

abstract：:The auditory steady state response (ASSR) is a sinusoidal evoked potential elicited by rapidly repeated auditory stimuli. The ASSR was recorded in eight patients during high-dose sufentanil anaesthesia for cardiac surgery in order to assess its usefulness as a measure of the level of consciousness. The electroencephal...

journal_title：British journal of anaesthesia

authors： Plourde G,Boylan JF

更新日期：1991-06-01 00:00:00

abstract：:In a prospective randomized multi-centre study, the mortality following internal fixation surgery for fracture of the upper femur was investigated in 538 elderly patients allocated to receive subarachnoid blockade or general (narcotic-relaxant) anaesthesia. The 28-day mortality was 6.6% with subarachnoid, and 5.9% wit...

journal_title：British journal of anaesthesia

authors： Davis FM,Woolner DF,Frampton C,Wilkinson A,Grant A,Harrison RT,Roberts MT,Thadaka R

更新日期：1987-09-01 00:00:00

abstract：Background:There is growing evidence that beta-blockade may reduce mortality in selected patients with sepsis. However, it is unclear if a pre-existing, chronic oral beta-blocker therapy should be continued or discontinued during the acute phase of severe sepsis and septic shock. Methods:The present secondary analysis...

journal_title：British journal of anaesthesia

authors： Fuchs C,Wauschkuhn S,Scheer C,Vollmer M,Meissner K,Kuhn SO,Hahnenkamp K,Morelli A,Gründling M,Rehberg S

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Beta-adrenergic agonists enhance behavioural and electroencephalographic arousal reactions. We explored whether adding esmolol, a short-acting beta(1)-adrenoceptor antagonist, to propofol anaesthesia modified the bispectral index (BIS) during induction of anaesthesia and orotracheal intubation. METHODS:Fift...

journal_title：British journal of anaesthesia

authors： Menigaux C,Guignard B,Adam F,Sessler DI,Joly V,Chauvin M

更新日期：2002-12-01 00:00:00

abstract：:We have investigated the effects of clonidine on gastric emptying of liquids in 30 patients. In a double-blind, randomized design, clonidine 150 micrograms, morphine 10 mg or saline in 1 ml was given i.m. One hour later, the patient drank a paracetamol solution (1.5 g in 50 ml water). Venous blood samples were obtaine...

journal_title：British journal of anaesthesia

authors： Asai T,McBeth C,Stewart JI,Williams J,Vaughan RS,Power I

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The surgical pleth index (SPI) is a measurement of intraoperative nociception. Evidence of its usability in children is limited. Given that the autonomic nervous system is still developing during the first years of life, the performance of the SPI on small children cannot be concluded from studies carried ou...

journal_title：British journal of anaesthesia

authors： Harju J,Kalliomäki ML,Leppikangas H,Kiviharju M,Yli-Hankala A

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Postoperative cognitive dysfunction (POCD) is a common complication in elderly patients after major surgery. An association between POCD and the development of dementia has been suspected. In this study, we assessed if POCD was a risk factor for the occurrence of dementia. METHODS:Danish patients enrolled b...

journal_title：British journal of anaesthesia

authors： Steinmetz J,Siersma V,Kessing LV,Rasmussen LS,ISPOCD Group.

更新日期：2013-06-01 00:00:00

abstract：:Procaine has been advocated in the treatment of malignant hyperpyrexia, whereas lignocaine has been shown to worsen the condition. Using muscle from patients susceptible to malignant hyperpyrexia in vitro, it has been demonstrated that muscle contracture can occur with procaine on its own, and in one patient the halot...

journal_title：British journal of anaesthesia

authors： Clarke IM,Ellis FR

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:The Alaris AEP monitor(TM) (Alaris, UK, version 1.4) is the first commercially available auditory evoked potential (AEP) monitor designed to estimate the depth of anaesthesia. It generates an "Alaris AEP index" (AAI), which is a dimensionless number scaled from 100 (awake) to 0. This study was designed to co...

journal_title：British journal of anaesthesia

authors： Kreuer S,Bruhn J,Larsen R,Hoepstein M,Wilhelm W

更新日期：2003-09-01 00:00:00

abstract：:The fate of gallamine triethiodide has been investigated in patients undergoing cholecystectomy with choledochostomy (group I), pelvic operations (group II) and orthopaedic operations (group III). Following a single i.v. injection of gallamine 2.5 mg kg(-1) the disappearance of the drug from the serum occurred in thre...

journal_title：British journal of anaesthesia

authors： Agoston S,Vermeer GA,Kersten UW,Scaf AH

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:There is considerable evidence that the use of tidal volumes <6 ml kg(-1) predicted body weight (PBW) reduces mortality in mechanically ventilated patients. We evaluated the effectiveness of using a large screen displaying delivered tidal volume in ml kg(-1) (PBW) for reducing tidal volumes. METHODS:We asse...

journal_title：British journal of anaesthesia

authors： Bourdeaux CP,Birnie K,Trickey A,Thomas MJ,Sterne J,Donovan JL,Benger J,Brandling J,Gould TH

更新日期：2015-08-01 00:00:00

abstract：:The rapid detection and evaluation of patients presenting with perioperative neurological dysfunction is of great clinical relevance. Biomarkers have been defined as biological molecules that can be used as an indicator of new onset or progression of a biological process or effect of treatment. Biomarkers have become ...

journal_title：British journal of anaesthesia

authors： Cata JP,Abdelmalak B,Farag E

更新日期：2011-12-01 00:00:00