Abstract：
OBJECTIVE:The goal of our study was to investigate the impact of dysthymic disorder (DD), a form of chronic depression, on naturalistic outcome in individuals with personality disorders (PDs). METHOD:The Collaborative Longitudinal Personality Disorders Study is a cohort initially including 573 subjects with 4 targeted PDs (borderline, avoidant, schizotypal, and obsessive-compulsive) and 95 subjects with major depression but no PD. At baseline, 115 subjects were diagnosed with coexisting DD, of whom 109 (94.8%) were PD subjects. Regression analyses were performed to predict 3 classes of broad clinical outcome after 2 years of prospective follow-up. We hypothesized that DD diagnosis at baseline would be associated with worse outcome on (1) persistence of a PD diagnosis, (2) impairment in psychosocial functioning (as measured by the Longitudinal Interval Follow-up Evaluation), and (3) crisis-related treatment utilization. RESULTS:Baseline DD diagnosis was associated with persistence of PD diagnosis at 2 years, particularly for borderline and avoidant PDs. It was associated with worse outcome on global social adjustment, life satisfaction, recreation, and friendships, but not employment or relationship with spouse. Contrary to expectation, DD did not increase suicide attempts, emergency room visits, or psychiatric hospitalizations. CONCLUSIONS:Comorbidity of DD is associated with persistence of PD diagnosis and with worse outcome on many, but not all, measures of psychosocial functioning.
journal_name
Compr Psychiatryjournal_title
Comprehensive psychiatryauthors
Hellerstein DJ,Skodol AE,Petkova E,Xie H,Markowitz JC,Yen S,Gunderson J,Grilo C,Daversa MT,McGlashan THdoi
10.1016/j.comppsych.2009.11.002subject
Has Abstractpub_date
2010-09-01 00:00:00pages
449-57issue
5eissn
0010-440Xissn
1532-8384pii
S0010-440X(09)00133-3journal_volume
51pub_type
杂志文章abstract：:Based on a representative sample of elderly subjects, a description of the limitations in activities of daily living (ADL) and instrumental ADL (IADL) at subthreshold levels of dementia and depression is presented and compared against a sample of psychiatric non-cases and samples with specified levels of the respectiv...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(00)80004-8
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:Diabetes mellitus, classified into types 1 and 2, is a chronic disease that shows high comorbidity with psychiatric disorders. Insulin-dependent patients show a higher prevalence of psychiatric disorders than do patients with type 2 diabetes. METHODS:This research involved the participation of 200 subjects ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2012.03.011
更新日期：2012-11-01 00:00:00
abstract：:Fifty-one adolescent-onset anorexia nervosa (AN) cases recruited after community screening were compared with 51 age-, sex-, and school-matched cases with regard to personality disorders and autism-spectrum disorders (ASD)/empathy disorders at age 21 years. All 102 cases had originally been examined at a mean age of 1...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(95)90100-a
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:There is a lack of data about residual symptoms in Chinese patients with depression. The aim of this study was to evaluate the association of residual symptoms with social functional impairment in these patients. METHODS:This was a multicenter cross-sectional study conducted in 11 hospitals in eight cities o...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2020.152164
更新日期：2020-01-22 00:00:00
abstract：:The Munchausen By Proxy Syndrome (MbPS) is a complicated phenomenon whereby a peculiar threefold relationship between perpetrator, victim, and medical staff develops. This triad is based on abuse of the child, deception of the doctor, and, in many cases, self-abuse or passivity of the victim towards the perpetrator's ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,评审
doi：10.1016/0010-440x(89)90083-7
更新日期：1989-11-01 00:00:00
abstract：:Age-specific suicide rates in the United States between 1951 and 1988 were shown in cohort, cross-sectional, and age group formats. Despite considerable variation among women and younger and older men, suicide rates among 40- to 44-year-old men have remained stable. Since suicide is strongly influenced by psychosocial...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(96)90039-5
更新日期：1996-05-01 00:00:00
abstract：BACKGROUND:An anxious-retarded subtype of major depressive disorder, defined by high scores for both anxiety and retardation, has been derived from melancholia and appeared to have higher external validity in terms of poor outcome and vasopressinergic stress hormone regulation. A specific personality could enhance the ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2007.04.002
更新日期：2007-09-01 00:00:00
abstract：:We describe our experience with a case of folie à famille with role reversal, including the long-term course. In addition, the case reports published since 1974 were reviewed and an overview is given of the psychoanalytic and system theory concepts on the pathogenesis of induced psychotic disorder. The inductor often ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,评审
doi：10.1016/0010-440x(93)90056-a
更新日期：1993-03-01 00:00:00
abstract：:About one quarter of the more than 69,000 medical students in this country suffer symptoms of mental illness, including 7% to 18% with substance use disorders. Subjective distress and physical health needs of medical students are also common and have been linked to training stresses. This first large-scale study of me...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1053/comp.2001.19747
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:Little is known about the prevalence and incidence of traditional eating disorders (EDs, e.g., anorexia nervosa (AN), bulimia nervosa and binge eating disorder (BED)) in individuals with childhood onset neuropsychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD) and autism spectrum ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2015.12.009
更新日期：2016-04-01 00:00:00
abstract：:This study employed grade of membership (GoM) analysis in a clinical setting to determine if the DSM-III-R personality disorder (PD) diagnostic criteria cluster into recognizable disorders resembling the official axis II nosology. The GoM model, based on fuzzy-set theoretic concepts, explicitly examines medical diagno...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(99)90079-2
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVES:Poor treatment response is an important factor contributing to lack of treatment adherence. The goals of this research were to determine whether improvements in Positive and Negative Syndrome Scale (PANSS) symptom domains predict the likelihood of staying on treatment and whether differential responses to tr...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2010.12.003
更新日期：2012-01-01 00:00:00
abstract：:In this study, we aimed to determine the influence of various types of childhood trauma (CT) on cognitive functions in Chinese patients presented with schizophrenia. One hundred sixty-two patients were assessed with the Childhood Trauma Questionnaire-Short Form (CTQ-SF) and Repeatable Battery for the Assessment of Neu...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2017.04.010
更新日期：2017-07-01 00:00:00
abstract：:Despite the seriousness of acute medical and psychological consequences of cocaine abuse, little knowledge exists about the chronic effects of the drug. Investigation of a sample of abstinent freebase (crack) abusers in the Bahamas provides the first research evidence that prolonged cocaine abuse may result in persist...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(90)90045-t
更新日期：1990-07-01 00:00:00
abstract：:The relationship between personality and Delusional Disorder in still debated. The present study aimed to evaluate the role of personality features and emotional dispositions on the proneness to delusional beliefs, through the lens of a dimensional approach. 91 outpatients were administered the Structured Interview fo...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2018.07.002
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:Despite the increasing recognition in clinical practice of body image problems in other than appearance related mental disorders, the question remains how aspects of body image are affected in different disorders. The aim of this study was to measure body image in patients with a variety of mental disorders a...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2017.01.004
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:A single-item assessment of sad mood after remission from MDD is predictive of relapse, yet the mechanisms that play a role in depressive relapse remain poorly understood. METHODS:In 283 patients, remitted from recurrent depression (DSM-IV-TR criteria; HAM-D17 score ≤ 10), we examined emotional scarring, th...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2015.02.010
更新日期：2015-05-01 00:00:00
abstract：:Fire-setting is a serious and costly form of antisocial behavior. Our objective in this study was to examine the prevalence and correlates of intentional fire-setting behavior in the United States. Data were derived from a nationally representative sample of US residents 18 years and older. Structured psychiatric inte...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2009.06.002
更新日期：2010-05-01 00:00:00
abstract：OBJECTIVE:Sleep problems are a clinical and/or diagnostic feature for a broad array of mood, substance use, and anxiety disorders, including posttraumatic stress disorder (PTSD). Previous research by Leskin et al (Leskin GA, Woodward SH, Young HE, Sheikh J. Effects of comorbid diagnoses on sleep disturbance in PTSD. J ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2011.01.007
更新日期：2011-11-01 00:00:00
abstract：:The object of this study is to assess the internal validity of DSM-III personality constructs and to explore whether the constituent elements are better explained by an alternate internally coherent classification. A two-stage stratified random sample of subjects identified at the Baltimore site of the Epidemiologic C...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(94)90170-8
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:In exploration of the risk factors of the Chinese rural young suicide, previous researchers found low prevalence of mental problems, high degree of impulsivity, and great proportion of lethal pesticide consumption. It noticed that some of the young suicides in rural China did not intend to die from the suici...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2014.11.019
更新日期：2015-02-01 00:00:00
abstract：PURPOSE:The aim of this study was to evaluate the health-related quality of life (HRQoL) in bipolar type I (BD I) and schizoaffective (SQA) patients during a 2-year period in a naturalistic study. METHODS:This study was based on the data generated by the Bipolar Comprehensive Outcome Study, a prospective, non-interven...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2014.05.009
更新日期：2014-10-01 00:00:00
abstract：:The transition to alcohol dependence is supposed to occur during a critical period that begins with increased drinking and ends with a loss of control. This process may last about 3 to 4 years, and is modified by gender and accelerated by premorbid traits (e.g., novelty-seeking) and comorbid disorders (e.g., dissocial...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(00)80014-0
更新日期：2000-03-01 00:00:00
abstract：OBJECTIVES:The present study aimed to determine the prevalence and associated factors of orgasmic dysfunction among Malay women with type 2 diabetes mellitus in Malaysia. METHODS:This cross-sectional study involved 347 women (174 non diabetic and 173 diabetic subjects) who attended the diabetic clinic in a university ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2013.03.009
更新日期：2014-01-01 00:00:00
abstract：:Clinical and epidemiologic evidence has documented the significant associations between medical illnesses and psychiatric disorders. However, extensive research has focused on the comorbidity of medical conditions and depression, and most were cross sectional, focused on clinical samples, and grounded in DSM-III or DS...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2012.12.020
更新日期：2013-08-01 00:00:00
abstract：INTRODUCTION:Very few studies have explored the effect of exposure to disaster memorial reports in the media on long-term sleep quality during the recovery period and post-disaster era. This study investigated the relationship between exposure to memorial reports and adult survivors' long-term sleep quality 10 years af...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2019.152150
更新日期：2020-02-01 00:00:00
abstract：:The purpose of this study was to explore, throughout the life cycle, the prevalence of self-harm behaviors among psychiatric inpatients with and without borderline personality disorder (BPD). Psychiatric inpatients with BPD (n = 43) were compared to those without BPD (n = 40) with regard to self-reported self-harm beh...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1053/comp.2002.32354
更新日期：2002-05-01 00:00:00
abstract：BACKGROUND:The purpose of the current investigation was (1) to test whether the 3-factor structure of the 20-item Toronto Alexithymia Scale (TAS-20) corresponding to the theoretical conceptualization of the alexithymia construct could be recovered in a Greek translation of the scale (the TAS-20-G), (2) to assess if a 3...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2009.09.005
更新日期：2010-07-01 00:00:00
abstract：:Previous studies of cognitive functioning in bipolar disorder generally indicate that a more severe course of illness is associated with greater cognitive impairment. In particular, a history of greater number and longer duration of mood episodes predicts enduring cognitive deficits in euthymic patients. Shifting the ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2008.09.005
更新日期：2009-07-01 00:00:00
abstract：BACKGROUND:Pathological gambling (PG) is an important public health problem that is prevalent, costly to society, and associated with substance misuse, depression, domestic violence, crime, and suicide. Despite these challenges, little is known about the physical health and medical correlates of PG. The goal of this pr...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2012.07.001
更新日期：2013-02-01 00:00:00
