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Effect of childhood trauma on cognitive functions in a sample of Chinese patients with schizophrenia.

Abstract：

:In this study, we aimed to determine the influence of various types of childhood trauma (CT) on cognitive functions in Chinese patients presented with schizophrenia. One hundred sixty-two patients were assessed with the Childhood Trauma Questionnaire-Short Form (CTQ-SF) and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). We investigated the correlations between various types of CT, demographic characteristics, and cognitive functions. Significant negative correlations were observed in physical abuse (PA) and sexual abuse (SA) with the language score (r=-0.190, -0.216, respectively, p<0.05). Similarly, physical neglect (PN) and the total score of CTQ were negatively correlated with the attention score (r=-0.17, -0.206, p<0.05, respectively) as well as the total RBANS score (r=-0.199, -0.223, respectively P<0.05). PN was also negatively correlated with delayed memory (r=-0.167, p<0.05). Regressions analysis indicated significant negative correlations between PN and attention, as well as the cognitive total score (p<0.001). Furthermore, demographic variables (years of education, family income) and clinical characteristics (type of anti-psychotics, duration of illness and times of recurrence) were correlated with cognitive functions. The current study showed that different types of CT could impact specific cognitive functions in Chinese schizophrenia patients. Therefore, we recommend that trauma-focused mental interventions for schizophrenia patients should be developed and routinely offered to patients.

journal_name

Compr Psychiatry

journal_title

Comprehensive psychiatry

authors

Li XB,Bo QJ,Zhang GP,Zheng W,Wang ZM,Li AN,Tian Q,Liu JT,Tang YL,Wang CY

doi

10.1016/j.comppsych.2017.04.010

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

147-152

eissn

0010-440X

issn

1532-8384

pii

S0010-440X(16)30706-4

journal_volume

76

pub_type

杂志文章

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