Abstract:
:Patients who meet DSM-III-R criteria for a diagnosis of panic disorder often show a complex mixture of psychopathological symptoms, including panic attacks (spontaneous and situational), anxiety (anticipatory and generalized), phobias (fear and avoidance), depression/dysphoria, and social and occupational disability. Various theories about the pathogenesis of these symptoms have been advanced that focus on a given symptom (e.g., panic, phobia) being primary in these disorders, with concurrent symptoms seen as epiphenomena or as secondary and reactive to a core symptom. This study, conducted on a large sample of panic disorder patients (N = 1,168), examines the temporal sequential pattern of symptom improvement in these patients, and explores how these relationships relate to various pathogenic theories. Our multiple analyses, when considered together, tend not to support any pathogenic theory that views a given symptom as being central to the overall disorder; our findings have obvious implications for theoreticians and clinicians interested in the study and treatment of panic and anxiety disorders.
journal_name
Compr Psychiatryjournal_title
Comprehensive psychiatryauthors
Deltito JA,Argyle N,Buller R,Nutzinger D,Ottosson JO,Brandon S,Mellergard M,Shera Ddoi
10.1016/0010-440x(91)90003-usubject
Has Abstractpub_date
1991-03-01 00:00:00pages
120-9issue
2eissn
0010-440Xissn
1532-8384pii
0010-440X(91)90003-Ujournal_volume
32pub_type
临床试验,杂志文章,多中心研究,随机对照试验abstract::This study investigated the presence of obsessive-compulsive personality disorder (OCPD) in a group of 277 patients (88 with obsessive-compulsive disorder [OCD], 58 with major depressive disorder [MDD], and 131 with panic disorder [Panic]) to test the specificity of the relationship between OCPD and OCD. OCPD is stati...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(97)90051-1
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:Patients with obsessive compulsive disorder (OCD) have inferior social functioning compared to healthy controls, but the exact nature of these social deficits, and the underpinning mechanisms, are unknown. We sought to investigate social functioning in patients with OCD by measuring their involuntary/spontane...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2013.08.007
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The use of crack cocaine is a major public health concern in Brazil and internationally. Recent data suggest that childhood trauma is associated with worse outcomes among cocaine users. This study had the objective of evaluating the relationship of childhood trauma with executive functioning and impulsivity ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2011.04.058
更新日期:2012-04-01 00:00:00
abstract::Clinical and epidemiologic evidence has documented the significant associations between medical illnesses and psychiatric disorders. However, extensive research has focused on the comorbidity of medical conditions and depression, and most were cross sectional, focused on clinical samples, and grounded in DSM-III or DS...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2012.12.020
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Recent studies suggest that parents' awareness of their offspring's schizophrenia could influence their offspring's insight. Low patient insight is linked to impairment of specific cognitive abilities, and biological parents of schizophrenia patients have impaired capacities in these same domains. However, l...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2017.02.013
更新日期:2017-07-01 00:00:00
abstract::Dimensional approaches to psychiatric disorders have shown an increased relevance in the ongoing debate for the forthcoming Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. In line with previously validated instruments for the assessment of different mood, anxiety, eating and psychotic spectra, we...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2008.11.006
更新日期:2009-09-01 00:00:00
abstract::This study investigated several aspects of the validity of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition avoidant personality disorder (APD) construct, with emphasis on the psychometric properties of the diagnostic criteria and the prototype nature of the construct. A sample of 1,058 patien...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1016/j.comppsych.2006.01.006
更新日期:2006-09-01 00:00:00
abstract::Substance use disorders are associated with increased suicidal behavior. The suicidal behavior in patients without a history of illegal substance abuse, who consume benzodiazepines (BZDs) regularly in doses higher than those recommended, has not been previously studied. The aim of this study was to investigate the fac...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1053/comp.2002.35912
更新日期:2002-11-01 00:00:00
abstract::A dysfunction of pursuit eye tracking in psychiatric patients has been well documented, but its cause has not. Recent speculation implicates a pathological disinhibition of saccades in these patients. However, great variability in tracking performance was found among nine normal subjects, and tracking quality improved...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(90)90009-h
更新日期:1990-05-01 00:00:00
abstract:BACKGROUND:High levels of anhedonia have been found in patients with schizophrenia; specifically they report higher levels of social anhedonia rather than physical anhedonia, and further, in the anticipatory rather than consummatory facets of pleasure. Nonetheless, contrasting results emerged regarding the underlying m...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2015.07.011
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Little is known about the prevalence and incidence of traditional eating disorders (EDs, e.g., anorexia nervosa (AN), bulimia nervosa and binge eating disorder (BED)) in individuals with childhood onset neuropsychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD) and autism spectrum ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2015.12.009
更新日期:2016-04-01 00:00:00
abstract::The symptomatological and diagnostic differentiations and outcome of acute psychosis were studied in 50 Egyptian patients using the Schedule of Clinical Assessment of Acute Psychotic States (SCAAPS). The prevailing symptoms were delusions, worry, irritability, mood changes, and disturbed behavior. Sixty-four percent o...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(93)90029-4
更新日期:1993-01-01 00:00:00
abstract::The impact of concurrent axis I diagnoses and axis II traits on the efficacy of a 22-session exposure-based treatment program for 43 outpatients with panic disorder and agoraphobia (PDA) and 63 with obsessive-compulsive disorder (OCD) was examined. Trained interviewers used the Structured Clinical Interview for DSM-II...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1053/comp.2001.19746
更新日期:2001-01-01 00:00:00
abstract::The Five-Minute Speech Sample (FMSS) is a brief measure for the assessment of expressed emotion (EE). No prior studies have investigated the validity of the FMSS in comparison to the Camberwell Family Interview (CFI) in Japan. Therefore, we administered the CFI and the FMSS to schizophrenic families in an attempt to e...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(99)90143-8
更新日期:1999-09-01 00:00:00
abstract::Research has revealed that despite many similarities, siblings raised within the same household have also been found to be markedly different from one another. Behavioral differences between siblings have been primarily attributed to differential exposure to a wide variety of environmental influences. The potential ro...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2013.06.002
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The purpose of the current investigation was (1) to test whether the 3-factor structure of the 20-item Toronto Alexithymia Scale (TAS-20) corresponding to the theoretical conceptualization of the alexithymia construct could be recovered in a Greek translation of the scale (the TAS-20-G), (2) to assess if a 3...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2009.09.005
更新日期:2010-07-01 00:00:00
abstract::We examined the prevalence and correlates of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) risk behaviors in a large sample of severely mentally ill (SMI) patients. Risk levels were correlated with demographic factors, diagnosis, symptom severity, trauma history, post-traumatic stress di...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1053/comp.2001.24576
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Diabetes mellitus, classified into types 1 and 2, is a chronic disease that shows high comorbidity with psychiatric disorders. Insulin-dependent patients show a higher prevalence of psychiatric disorders than do patients with type 2 diabetes. METHODS:This research involved the participation of 200 subjects ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2012.03.011
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:Coercive and disruptive behaviors (CDBs) are commonplace in pediatric obsessive-compulsive disorder (OCD) and are associated with increased disorder impact and reduced treatment response. Prior research suggests that CDBs mediate the cross-sectional relationship between family accommodation and OCD symptom seve...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2018.07.012
更新日期:2018-10-01 00:00:00
abstract:INTRODUCTION:Dopamine receptor polymorphisms have been associated with specific patterns of novelty seeking (NS) temperamental nature and frontal executive function. In addition, carriers of dopamine receptor type 2 (DRD2)-TaqI A1 have been hypothesized to be potentially vulnerable to addictive behaviors. In the presen...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2008.01.008
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:Recent research suggests that there are clinical and biologic characteristics typical of late onset depression (LOD). Furthermore, evidence has been put forward that LOD may be a prodrome of dementia. OBJECTIVE:This study aims to assess the association between LOD and the development of dementia. SETTING:T...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2010.10.016
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Despite controversy surrounding the construct of food addiction, its relationship with obesity and the validity of the Yale Food Addiction Scale (YFAS), have become emerging fields of study. No prior research has examined the prevalence and correlates of food addiction, and validation of the Modified Yale Fo...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2018.03.006
更新日期:2018-07-01 00:00:00
abstract::We conducted a household survey of 3,012 adults aged 18 and over in order to estimate the prevalence of DSM-IV obsessive-compulsive disorder (OCD) in urban areas in Konya, Turkey. Trained psychiatry interns administered the 2.1 version of the OCD section of the Composite International Diagnostic Interview (CIDI). The ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2004.06.009
更新日期:2004-09-01 00:00:00
abstract::The study attempted to determine the extent of dissociative experiences and the prevalence of dissociative disorders (DDs) in a series of acute psychiatric inpatients and to correlate these experiences and disorders with some sociodemographic, clinical, and historical variables. A total of 207 consecutively admitted p...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(96)90017-6
更新日期:1996-09-01 00:00:00
abstract::The purpose of this study was to develop and test the Talbieh Brief Distress Inventory (TBDI), a 24-item self-report questionnaire that measures psychological distress among immigrants. The TBDI combines items from the Brief Symptom Inventory (BSI) and the Psychiatric Epidemiology Research Interview Demoralization Sca...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(95)90253-8
更新日期:1995-11-01 00:00:00
abstract::The goal of this study is to replicate an earlier epidemiological finding of seasonal changes in mood and behavior among Chinese medical students using an independent study population. Three hundred nineteen college students were surveyed with a Chinese version of the Seasonal Pattern Assessment Questionnaire (SPAQ) a...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(00)90132-9
更新日期:2000-01-01 00:00:00
abstract::Exposure to earthquakes has been associated with psychological distress in particular, the development of posttraumatic stress disorder (PTSD). The aims of this study are to estimate the prevalence of PTSD, explore the associated risk factors among survivors 1 year after the Wenchuan earthquake in China, and compare t...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2010.08.002
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:Adult attention deficit/hyperactivity disorder (ADHD) exhibits symptoms, such as attention deficit and impulsivity, that make it difficult for patients to manage social activities. In this study, we investigated the association of adult ADHD symptoms with temperament and character dimensions, taking into acco...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2016.07.003
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:This study was conducted to examine whether pediatric patients with obsessive-compulsive disorder (OCD) and hoarding symptoms differed in terms of clinical characteristics from pediatric OCD patients without hoarding symptoms. METHOD:Eighty children and adolescents with OCD (range, 7-17 years) completed clin...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2007.03.001
更新日期:2007-07-01 00:00:00
abstract::Kinsey concluded that homosexuality and heterosexuality were distributed dimensionally in the normal population, a significant percentage of whom experienced homosexual feelings. This conclusion has been ignored by most sex researchers. Twenty men seeking treatment for compulsive sexual behaviours reported a dimension...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(91)90069-o
更新日期:1991-01-01 00:00:00