Abstract:
:The primary purpose of this study was to assess the prevalence of major psychiatric disorders in human immunodeficiency virus-positive (HIV+) men with acquired immune deficiency syndrome (AIDS)-defining conditions. Secondary goals were to identify correlates of distress and psychopathology, and to determine whether there is a gradient of distress associated with progressive HIV illness. One hundred twelve men with AIDS-defining conditions, 61 HIV+ men without AIDS, and 84 HIV-seronegative gay men were assessed. Measures included the Structured Clinical Interview for DSM-IV (SCID), Hamilton Rating Scale for Depression (HAM-D), and other dimensional measures of distress and outlook, as well as laboratory markers of HIV stage, including HIV RNA viral load assays. Rates of major depression, consistent with other findings, were in the 5% to 10% range. Mean scores on dimensional measures of distress and outlook were within the "not depressed" range and did not increase despite increasing HIV illness severity. However, rates of dysthymia were elevated among men with CD4 cell counts less than 500, and the cumulative rates of any current axis I depressive disorder for three of the four study groups were in the range of 15% to 20%. The strongest correlates of dimensional measures of distress were current HIV symptoms and social support, and to a lesser extent, a lifetime history of major depression and current use of antidepressants and/or anxiolytics. Overall, most men displayed effective adaptation to illness, but a significant minority experienced moderate psychological distress, which warrants consideration by health providers who serve this population.
journal_name
Compr Psychiatryjournal_title
Comprehensive psychiatryauthors
Rabkin JG,Ferrando SJ,Jacobsberg LB,Fishman Bdoi
10.1016/s0010-440x(97)90067-5subject
Has Abstractpub_date
1997-05-01 00:00:00pages
146-54issue
3eissn
0010-440Xissn
1532-8384pii
S0010-440X(97)90067-5journal_volume
38pub_type
杂志文章abstract:OBJECTIVE:A number of studies about attention-deficit/hyperactivity disorder (ADHD) and Internet video game play have examined the prefrontal cortex and dopaminergic system. Stimulants such as methylphenidate (MPH), given to treat ADHD, and video game play have been found to increase synaptic dopamine. We hypothesized ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2008.08.011
更新日期:2009-05-01 00:00:00
abstract::Separation anxiety disorder is well recognized as a juvenile psychiatric disorder, but it appears to be rarely diagnosed in adulthood. Drawing on our clinical impressions and a review of the relevant literature, we sought to investigate whether separation anxiety symptoms could be identified in adulthood. Forty-four s...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(97)90060-2
更新日期:1997-09-01 00:00:00
abstract::Fifty-one adolescent-onset anorexia nervosa (AN) cases recruited after community screening were compared with 51 age-, sex-, and school-matched cases with regard to personality disorders and autism-spectrum disorders (ASD)/empathy disorders at age 21 years. All 102 cases had originally been examined at a mean age of 1...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(95)90100-a
更新日期:1995-01-01 00:00:00
abstract::Despite the seriousness of acute medical and psychological consequences of cocaine abuse, little knowledge exists about the chronic effects of the drug. Investigation of a sample of abstinent freebase (crack) abusers in the Bahamas provides the first research evidence that prolonged cocaine abuse may result in persist...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(90)90045-t
更新日期:1990-07-01 00:00:00
abstract::From a total sample of 1,448 psychiatric outpatients, 175 (12.1%) received a diagnosis of a somatoform disorder according to DSM-III-R criteria. One hundred twenty-two (70%) of these patients had another current axis I diagnosis, and this rate increased to 79% (139 of 175) when lifetime psychiatric diagnoses were reco...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(99)90131-1
更新日期:1999-07-01 00:00:00
abstract:BACKGROUND:Fibromyalgia (FM) is a common syndrome whose main characteristic is chronic widespread musculoskeletal pain, the severity of which is frequently worsened by concomitant obesity. Major depression (MD), particularly as part of a bipolar spectrum disorder (BSD), is associated with both obesity and FM. OBJECTIV...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2017.08.006
更新日期:2018-01-01 00:00:00
abstract::The present study investigated the association of specific personality characteristics with agoraphobia, and whether they predicted long-term outcome following a group cognitive behavior therapy program. Thirty-three patients with agoraphobia with panic attacks, 18 with social phobia, and 26 "normals" were used in the...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(92)90038-r
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVE:This study aimed to examine the rate and predictive factors of successful employment at 3 months upon enrolment into an employment program among patients with severe mental illness (SMI). METHODS:A cross-sectional study using universal sampling technique was conducted on patients with SMI who completed a 3-m...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2013.03.011
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the differences in spirituality among adult patients with depressive disorders, who had suffered various types of abuse or neglect in childhood. METHODS:A total of 305 outpatients diagnosed with depressive disorders completed questionnaires on socio-demographic variab...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2016.04.003
更新日期:2016-08-01 00:00:00
abstract::The current status of subjective experiences in schizophrenia is examined. Subjective experiences are very frequent disorders in schizophrenic patients, and their study has been largely neglected. Recently, a number of scales that evaluate subjective experiences have been published, and although the psychometric prope...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章,评审
doi:10.1016/0010-440x(94)90192-9
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:High levels of anhedonia have been found in patients with schizophrenia; specifically they report higher levels of social anhedonia rather than physical anhedonia, and further, in the anticipatory rather than consummatory facets of pleasure. Nonetheless, contrasting results emerged regarding the underlying m...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2015.07.011
更新日期:2015-10-01 00:00:00
abstract::We report the initial results from a prospective study designed to assess patients' functional outcome and level of service utilization following psychiatric hospitalization. All patients admitted between March 31, 1993 and April 1, 1994 were interviewed at admission and discharge, and 350 consenting patients were rea...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(96)90571-4
更新日期:1996-03-01 00:00:00
abstract::Research has revealed that despite many similarities, siblings raised within the same household have also been found to be markedly different from one another. Behavioral differences between siblings have been primarily attributed to differential exposure to a wide variety of environmental influences. The potential ro...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2013.06.002
更新日期:2014-01-01 00:00:00
abstract:AIMS:The aim of this study was to compare conversion disorder patients with healthy controls in terms of temperament and character, and to determine the effect of these characteristics on comorbid depression, based on the idea that conversion disorder patients may have distinctive temperament and character qualities. ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2012.10.007
更新日期:2013-05-01 00:00:00
abstract::The symptomatological and diagnostic differentiations and outcome of acute psychosis were studied in 50 Egyptian patients using the Schedule of Clinical Assessment of Acute Psychotic States (SCAAPS). The prevailing symptoms were delusions, worry, irritability, mood changes, and disturbed behavior. Sixty-four percent o...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(93)90029-4
更新日期:1993-01-01 00:00:00
abstract::Ten normal, wakeful, young (average age, 25.3 +/- 6.6 years) male subjects received positron emission tomographic (PET) scans 45 to 120 minutes after an infusion of D-[18 F]deoxyglucose in order to assess localized cerebral glucose metabolic rates during silent visual and other sensory imagery and cognitive mentation....
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(92)90080-a
更新日期:1992-01-01 00:00:00
abstract::The purpose of this study was to explore, throughout the life cycle, the prevalence of self-harm behaviors among psychiatric inpatients with and without borderline personality disorder (BPD). Psychiatric inpatients with BPD (n = 43) were compared to those without BPD (n = 40) with regard to self-reported self-harm beh...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1053/comp.2002.32354
更新日期:2002-05-01 00:00:00
abstract::We hypothesized that communication disturbances in the form of unclear linguistic references in schizophrenia are associated with excess-related pathophysiologic processes in some individuals and deficit-related processes in others. We divided a sample of 28 acutely ill schizophrenic inpatients into two groups: those ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(95)90079-b
更新日期:1995-05-01 00:00:00
abstract::This study investigated the presence of obsessive-compulsive personality disorder (OCPD) in a group of 277 patients (88 with obsessive-compulsive disorder [OCD], 58 with major depressive disorder [MDD], and 131 with panic disorder [Panic]) to test the specificity of the relationship between OCPD and OCD. OCPD is stati...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(97)90051-1
更新日期:1997-01-01 00:00:00
abstract::Primary hyperhidrosis is characterized by excessive sweating and often accompanied by social avoidance. Social anxiety disorder (SAD) is characterized by fear and avoidance of social situations, often partly related to fears of showing signs of excessive autonomic nervous system activation, such as sweating. To clarif...
journal_title:Comprehensive psychiatry
pub_type: 临床试验,杂志文章
doi:10.1016/j.comppsych.2012.04.009
更新日期:2012-11-01 00:00:00
abstract::Seventy-two percent of 86 major depressive patients with atypical features as defined by the DSM-IV and evaluated systematically were found to meet our criteria for bipolar II and related "soft" bipolar disorders; nearly 60% had antecedent cyclothymic or hyperthymic temperaments. The family history for bipolar disorde...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(98)90080-3
更新日期:1998-03-01 00:00:00
abstract::Our aim was to describe the clinical features of 35% CO2-induced panic attacks in patients with panic disorder (PD) (Diagnostic and Statistical Manual and Mental Disorders, Fourth Edition) and compare them with the last spontaneous panic attack in patients with PD who had not had a panic attack after the 35% CO2 chall...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.comppsych.2005.07.007
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:This study was conducted to examine whether pediatric patients with obsessive-compulsive disorder (OCD) and hoarding symptoms differed in terms of clinical characteristics from pediatric OCD patients without hoarding symptoms. METHOD:Eighty children and adolescents with OCD (range, 7-17 years) completed clin...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2007.03.001
更新日期:2007-07-01 00:00:00
abstract::The relationship between personality and Delusional Disorder in still debated. The present study aimed to evaluate the role of personality features and emotional dispositions on the proneness to delusional beliefs, through the lens of a dimensional approach. 91 outpatients were administered the Structured Interview fo...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2018.07.002
更新日期:2018-08-01 00:00:00
abstract::The aim of the present study was to examine cognitive performance and basic symptoms (BS) in the relatives of schizophrenic patients. The experimental sample comprised 24 first-degree relatives of patients. Each relative was matched to one control. Cognitive tests were: Continuous Performance Test (CPT), N-Back Workin...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.comppsych.2008.01.001
更新日期:2008-07-01 00:00:00
abstract::Investigation of relationship patterns between co-occurring symptoms has greatly improved the efficacy of psychiatric care. Depression and anxiety often present together, and identification of primary vs secondary psychiatric symptoms has implications for treatment. Previous psychotherapy research investigating the re...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.comppsych.2008.06.009
更新日期:2009-03-01 00:00:00
abstract::Co-occurring substance abuse is common among people with chronic mental illnesses such as schizophrenia. Although gender differences have been established among substance abusers in the general population and among people with schizophrenia, little is known about gender differences in people with the dual disorders of...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(97)90090-0
更新日期:1997-03-01 00:00:00
abstract::The relationship between subjective quality of life (QOL) and suicide attempts in patients with schizophrenia has been understudied. The current study tested the hypothesis that QOL is negatively associated with a history of suicidality of patients with schizophrenia. QOL, as measured by the Quality of Life Enjoyment ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/S0010-440X(03)00146-9
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:Psychotic symptoms are commonly observed among heroin users. Low serum brain-derived neurotrophic factor (BDNF) levels have been reported in schizophrenia and psychosis; however, studies assessing the relationship between serum BDNF levels and psychotic symptoms in heroin dependence are lacking. METHOD:A to...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2015.06.008
更新日期:2015-10-01 00:00:00
abstract::In this report, a first comprehensive description of the clinical features of patients with organic mood syndrome, depressed type (OMS-D), in a psychiatric hospital population is presented. This description is based on information from 130 OMS-D patients among 14,889 patients who presented for initial evaluation over ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(93)90071-b
更新日期:1993-11-01 00:00:00