Abstract：
:Our aim was to describe the clinical features of 35% CO2-induced panic attacks in patients with panic disorder (PD) (Diagnostic and Statistical Manual and Mental Disorders, Fourth Edition) and compare them with the last spontaneous panic attack in patients with PD who had not had a panic attack after the 35% CO2 challenge test. We examined 91 patients with PD submitted to the CO2 challenge test. The test consisted of exhaling as fully as possible, took a fast vital capacity breath, held their breath for 8 seconds, exhaled, and then repeated the fast vital capacity breath, again holding for 8 seconds. The patients inhaled the 35% CO2/65% O2 mixture or atmospheric compressed air, randomly selected in a double-blind design. Scales were applied before and after the test. A total of 68.1% (n = 62) patients with PD had a panic attack (responders) after the CO2 test (chi2(1) = 25.87, P = .031). The last spontaneous panic attack and the symptom profile from the patients with PD who had not had a panic attack after the test (n = 29, 31.9%) were described to compare. The responders had more respiratory symptoms (chi2(1) = 19.21, P < .001), fulfilling the criteria for respiratory PD subtype (80.6%); the disorder started earlier (Mann-Whitney, P < .001), had a higher familial prevalence of PD (chi2(1) = 20.45, P = .028), and had more previous depressive episodes (chi2(1) = 27.98, P < .001). Our data suggest that there is an association between respiratory PD subtype and hyperreactivity to a CO2 respiratory challenge test. The responders may be a subgroup of respiratory PD subtype with future diagnostic and therapeutic implications.
journal_name
Compr Psychiatryjournal_title
Comprehensive psychiatryauthors
Nardi AE,Valença AM,Lopes FL,Nascimento I,Veras AB,Freire RC,Mezzasalma MA,de-Melo-Neto VL,Zin WAdoi
10.1016/j.comppsych.2005.07.007subject
Has Abstractpub_date
2006-05-01 00:00:00pages
209-14issue
3eissn
0010-440Xissn
1532-8384pii
S0010-440X(05)00086-6journal_volume
47pub_type
杂志文章,随机对照试验abstract：:The present study sought to determine concordance of cognitive impairment among elderly female twins. Cognitive testing was performed by telephone interview in a sample of 100 female-female twins older than 65 years. The participants were 32 monozygotic (MZ) and 18 dizygotic (DZ) female twin pairs, all between the age...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1053/comp.2003.50019
更新日期：2003-03-01 00:00:00
abstract：BACKGROUND:Insight into having a psychotic disorder is often considered to be a positive characteristic that improves quality of life. However, the evidence regarding this controversy is mixed. The present study examined the relation between insight and quality of life. METHOD:One hundred thirty-one participants with ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2005.08.006
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:The present study examined the hypothesis that patients' ratings would be less congruent and stable if they were asked to rate imprecise terms on frequency and intensity that were embedded in a behavioral or perceptual framework. Based on data acquired from the patients' ratings the presented terms were anal...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2014.06.010
更新日期：2014-11-01 00:00:00
abstract：AIMS:The aim of this study was to compare conversion disorder patients with healthy controls in terms of temperament and character, and to determine the effect of these characteristics on comorbid depression, based on the idea that conversion disorder patients may have distinctive temperament and character qualities. ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2012.10.007
更新日期：2013-05-01 00:00:00
abstract：:Previous studies indicate that first-episode and chronic schizophrenic patients do not differ regarding neuropsychological performance as assessed with standard cognitive tasks. For the present study, it was investigated whether first-episode and chronic schizophrenics report similar subjective cognitive deficits. The...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1053/comp.2001.23144
更新日期：2001-05-01 00:00:00
abstract：OBJECTIVE:The aims of this study were to understand the mental health of single fathers relative to married fathers as the population of single fathers continues to increase and to use the resultant data for the establishment of public health policies. METHODS:We evaluated the mental health of 58 single fathers and 25...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2014.09.012
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Neurocognitive difficulties are commonly reported by patients suffering from chronic fatigue syndrome (CFS). Moderate improvements from 'best practice' therapy are promising, but to date reported efficacy is based entirely on subjective measures. This is problematic, given the well-documented divergence betw...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2016.02.002
更新日期：2016-04-01 00:00:00
abstract：:Trichotillomania, the compulsive urge to pull out one's hair, is a poorly studied chronic condition affecting 2 to 8 million people, 90% of whom are women. Significant gains have been made about the nature and clinical presentation of this disorder, and yet conceptualizations of trichotillomania remain inconsistent an...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1053/comp.2000.9012
更新日期：2000-09-01 00:00:00
abstract：:Until the 1850s, obsessive-compulsive phenomena were considered to be a variant of the old notion of insanity. Around this time they became a separate disease: first, as a member of the old class of the neuroses; then, briefly, as a variant of the newly formed notion of psychosis; and finally, as a neurosis proper (in...
journal_title：Comprehensive psychiatry
pub_type： 历史文章,杂志文章
doi：10.1016/0010-440x(89)90052-7
更新日期：1989-07-01 00:00:00
abstract：OBJECTIVES:Poor treatment response is an important factor contributing to lack of treatment adherence. The goals of this research were to determine whether improvements in Positive and Negative Syndrome Scale (PANSS) symptom domains predict the likelihood of staying on treatment and whether differential responses to tr...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2010.12.003
更新日期：2012-01-01 00:00:00
abstract：:Two hundred twenty-four first-degree relatives of patients with psychotic disorders were administered the Structured Interview for DSM-III Personality Disorders (SIDP) and completed a self-report instrument to assess dimensions of the five-factor model of personality. All of the DSM-III personality disorders were rela...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(93)90003-m
更新日期：1993-07-01 00:00:00
abstract：AIM:The objective of this paper is to introduce the concept of late catatonia to foreign readers for the first time in English. METHODS:The original study was conducted about 20 years ago. The subjects were 16 persons who first visited our institutions between 1990 and 1996. They fulfilled the following criteria: 1) l...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2014.07.003
更新日期：2014-10-01 00:00:00
abstract：:The emergence of obsessive-compulsive symptoms during clozapine treatment has been reported in recent case studies, yet the incidence and significance of this finding is still unclear pending reliable data from a larger sample of patients. Hospital records of 142 randomly selected inpatients started on clozapine treat...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(95)90071-3
更新日期：1995-07-01 00:00:00
abstract：:Obesity is associated with several symptoms that are components of the diagnostic criteria for major depressive disorder (MDD). Compared with nonobese individuals, obese individuals report more fatigue, sleep disturbance, and overeating. Obesity might, therefore, impact the psychometric properties of the MDD criteria....
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2010.05.001
更新日期：2011-03-01 00:00:00
abstract：:The history of antipsychotic drug development has had a long and torturous course, often based on chance findings that bear little relationship to the intellectual background driving observations. In 1891, Paul Ehrlich observed the antimalarial effects of methylene blue, a phenothiazine derivative. Later, the phenothi...
journal_title：Comprehensive psychiatry
pub_type： 历史文章,杂志文章,评审
doi：10.1016/s0010-440x(99)90082-2
更新日期：1999-11-01 00:00:00
abstract：OBJECTIVE:The Eating Disorder Inventory (EDI) is used worldwide in research and treatment of eating disorders (EDs). Using the latest version (EDI-3: 91 items), we extracted the best screening items for a diagnosis of anorexia (AN) and bulimia (BN) nervosa. METHOD:A patient sample of 561 women was recruited from an ED...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2013.05.004
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:Despite increasing recognition of the potentially severe medical and psychosocial costs of pathologic skin picking (PSP), no large-sample, randomized investigation of its prevalence in a national population has been conducted. METHOD:Two thousand five hundred and thirteen US adults were interviewed during th...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2009.04.003
更新日期：2010-03-01 00:00:00
abstract：:Recent studies have suggested an association between childhood physical and sexual abuse and adult dissociative experiences. The purpose of this study was to determine the relationship of both childhood and adult-onset abuse and their characteristics for adult dissociative symptoms. One hundred forty-four psychiatric ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(96)90005-x
更新日期：1996-07-01 00:00:00
abstract：BACKGROUND:Social support and sense of mastery are considered important resources in coping both with serious mental illness (SMI) and with motherhood-related challenges. However, their interactive effects on the parental stress of mothers with SMI are not clear. METHODS:Scales assessing parental distress, social supp...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2018.08.015
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Depression after acute coronary syndromes (ACS) is an important risk factor for further coronary events; but the influence of anhedonia, the decreased capacity to experience pleasure, has received little attention. The aim of the study was to investigate the effects of anhedonia on prognosis at 3-year follow...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2009.01.011
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:Milder forms of depression are highly prevalent in the clinical setting as well as in primary care. However, it is still unclear whether there are distinguishable groups among the various subthreshold syndromes and to what extent they are associated with impairment, thus requiring treatment. Therefore, the s...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2005.04.007
更新日期：2006-01-01 00:00:00
abstract：:Co-occurring substance abuse is common among people with chronic mental illnesses such as schizophrenia. Although gender differences have been established among substance abusers in the general population and among people with schizophrenia, little is known about gender differences in people with the dual disorders of...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(97)90090-0
更新日期：1997-03-01 00:00:00
abstract：:The Defense Style Questionnaire (DSQ) assesses defensive behavior by empirically evaluating conscious derivatives of defense and coping mechanisms in everyday life. It was developed on the assumption that defenses can be ordered along a maturity-immaturity continuum and tend to group into clusters, or defensive styles...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2004.07.012
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:Pathologic levels of ritualistic avoidance (also known as active avoidance) are common in the clinical presentation of obsessive-compulsive disorder (OCD). Despite its clinical relevance, there has been little examination of active avoidance as a ritualistic compulsion in adults with OCD. OBJECTIVE:The obje...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2011.03.002
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:A number of studies about attention-deficit/hyperactivity disorder (ADHD) and Internet video game play have examined the prefrontal cortex and dopaminergic system. Stimulants such as methylphenidate (MPH), given to treat ADHD, and video game play have been found to increase synaptic dopamine. We hypothesized ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2008.08.011
更新日期：2009-05-01 00:00:00
abstract：:We describe our experience with a case of folie à famille with role reversal, including the long-term course. In addition, the case reports published since 1974 were reviewed and an overview is given of the psychoanalytic and system theory concepts on the pathogenesis of induced psychotic disorder. The inductor often ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,评审
doi：10.1016/0010-440x(93)90056-a
更新日期：1993-03-01 00:00:00
abstract：BACKGROUND:Various factors contribute to suicide. Psychological strains are hypothesized to precede suicidal thought and attempt. Life satisfaction can be a measure of relative deprivation strain and aspiration-reality strain. AIMS:This study was to compare the suicide attempters with various levels of life satisfacti...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2016.12.002
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:Childhood sexual abuse (CSA) is increasing, and current studies should address issues such as stigmas and casual attitudes that may be amenable to intervention. Thus, we aimed to investigate the effects of education on the attitudes of medical students toward CSA survivors. METHOD:We divided medical students...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2012.01.003
更新日期：2012-08-01 00:00:00
abstract：:A number of studies have examined the relationships between aggression and various facets of the work environment. However, to our knowledge, the relationship between self-reported aggressive behaviors and corresponding employment histories has never been previously explored. Using a cross-sectional approach and a sel...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2012.06.005
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:It is well documented that patients with schizophrenia have impoverished quality of life (QOL). Efforts to determine the underpinnings of this impoverishment have implicated negative symptoms more than positive or disorganized symptoms. However, only a minority of individuals with the liability to schizophren...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2008.11.002
更新日期：2009-09-01 00:00:00
