Abstract：
OBJECTIVE:It is well documented that patients with schizophrenia have impoverished quality of life (QOL). Efforts to determine the underpinnings of this impoverishment have implicated negative symptoms more than positive or disorganized symptoms. However, only a minority of individuals with the liability to schizophrenia will ever show manifest illness, and it is presently unclear the degree to which QOL is affected in individuals with subclinical symptoms of the disorder (ie, schizotypy). The present study examined the relative contributions of negative, positive, and disorganized schizotypy symptoms to QOL. METHODS:Measures of schizotypal symptoms and subjective and objective QOL were obtained from a sample of 1395 adults. RESULTS:Measures of schizotypal symptoms significantly corresponded to all measures of QOL, although the magnitude of correlations were significantly larger for subjective than objective measures. The negative symptom dimension explained a substantial portion of unique variance in the social domains of QOL above and beyond that accounted for by the other schizotypy dimensions. CONCLUSIONS:These findings highlight the deleterious impact of schizotypal symptoms, particularly negative symptoms. Further research clarifying the mechanism underlying this relationship is called for.
journal_name
Compr Psychiatryjournal_title
Comprehensive psychiatryauthors
Cohen AS,Davis TE 3rddoi
10.1016/j.comppsych.2008.11.002subject
Has Abstractpub_date
2009-09-01 00:00:00pages
408-14issue
5eissn
0010-440Xissn
1532-8384pii
S0010-440X(08)00168-5journal_volume
50pub_type
杂志文章abstract：:The present study investigates identity disorders in schizophrenics and borderlines. Nineteen schizophrenics and 17 borderlines were compared with 18 normal controls. The technique used was an adapted version of the repertory grid test to describe the self and nine significant others (i.e., family members). Three indi...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(95)90117-5
更新日期：1995-09-01 00:00:00
abstract：:Prison-based research has been limited due to concern that prisoners may represent a vulnerable population secondary to possible coercion and limited capacity for voluntary informed consent. This study was designed to assess decisional capacity and susceptibility to coercion in prison research subjects. Subjects were ...
journal_title：Comprehensive psychiatry
pub_type： 临床试验,杂志文章
doi：10.1016/j.comppsych.2003.09.009
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:Poor treatment response is an important factor contributing to lack of treatment adherence. The goals of this research were to determine whether improvements in Positive and Negative Syndrome Scale (PANSS) symptom domains predict the likelihood of staying on treatment and whether differential responses to tr...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2010.12.003
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:In addition to identified neuropsychiatric characteristic of systemic lupus erythematosus (SLE), changes in personality seem to occur in patients with SLE. Even in absence of an axis I psychiatric diagnosis, personality variations play important role in general wellbeing of these patients. This study investi...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2017.09.007
更新日期：2018-01-01 00:00:00
abstract：:A sample of depressed inpatients was subdivided according to their initial levels of cognitive dysfunction. These high cognitive dysfunction (HCD) patients and low cognitive dysfunction (LCD) patients received either pharmacotherapy or combined pharmacotherapy plus cognitive-behavioral psychotherapy. Treatments began ...
journal_title：Comprehensive psychiatry
pub_type： 临床试验,杂志文章
doi：10.1016/0010-440x(90)90055-w
更新日期：1990-01-01 00:00:00
abstract：OBJECTIVE:The goal of our study was to investigate the impact of dysthymic disorder (DD), a form of chronic depression, on naturalistic outcome in individuals with personality disorders (PDs). METHOD:The Collaborative Longitudinal Personality Disorders Study is a cohort initially including 573 subjects with 4 targeted...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2009.11.002
更新日期：2010-09-01 00:00:00
abstract：:Some patients with Tourette's syndrome (TS) remain disabled despite conventional treatment. Recently, neurosurgical procedures have been reported to be potentially effective interventions for such intractable cases. Clinicians are now being asked to make recommendations to patients about these candidate operations. Th...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,评审
doi：10.1016/s0010-440x(95)90109-4
更新日期：1995-03-01 00:00:00
abstract：OBJECTIVE:Despite increasing recognition of the potentially severe medical and psychosocial costs of pathologic skin picking (PSP), no large-sample, randomized investigation of its prevalence in a national population has been conducted. METHOD:Two thousand five hundred and thirteen US adults were interviewed during th...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2009.04.003
更新日期：2010-03-01 00:00:00
abstract：:The aim of this study was to examine the role of emotions like pity and anger in mediating the relationship between beliefs about the controllability of a mental illness, and the willingness to help someone with a mental illness. In particular, we tested the hypothesis that the effects of beliefs about controllability...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.comppsych.2012.11.004
更新日期：2013-07-01 00:00:00
abstract：:Advances in the neurobiology of obsessive-compulsive disorder (OCD) have raised the possibility that animal models in general and neuroethological models in particular may be useful in understanding and investigating this illness. One neuroethologically oriented model is that of canine acral lick dermatitis. In this r...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,评审
doi：10.1016/0010-440x(92)90053-s
更新日期：1992-07-01 00:00:00
abstract：:Cloninger's psychobiological model of temperament and character postulates that each of the temperament dimensions is associated with a specific emotional experience, depending on the situational cues. The aim of the present study was to test this postulate in a variety of challenging experimental tasks. The participa...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2004.07.023
更新日期：2005-03-01 00:00:00
abstract：:We have reported elsewhere the development of a brief version of the Parental Bonding Instrument (PBI), which we have called the Parental Bonding Instrument-Brief Current form (PBI-BC), for use in survey research in adolescent samples. It was shown in that report that PBI-BC retained the factor structure of the origin...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(92)90059-y
更新日期：1992-11-01 00:00:00
abstract：:About one quarter of the more than 69,000 medical students in this country suffer symptoms of mental illness, including 7% to 18% with substance use disorders. Subjective distress and physical health needs of medical students are also common and have been linked to training stresses. This first large-scale study of me...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1053/comp.2001.19747
更新日期：2001-01-01 00:00:00
abstract：:We conducted a household survey of 3,012 adults aged 18 and over in order to estimate the prevalence of DSM-IV obsessive-compulsive disorder (OCD) in urban areas in Konya, Turkey. Trained psychiatry interns administered the 2.1 version of the OCD section of the Composite International Diagnostic Interview (CIDI). The ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2004.06.009
更新日期：2004-09-01 00:00:00
abstract：BACKGROUND:Poor attention is paid by recent research to the prevalence of mental well-being in psychiatric patients and the comparison between groups with different diagnoses. Data suggest that the presence of mental illness does not necessarily mean the absence of well-being, particularly in stable outpatients. METHO...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2019.02.001
更新日期：2019-05-01 00:00:00
abstract：:The impact of concurrent axis I diagnoses and axis II traits on the efficacy of a 22-session exposure-based treatment program for 43 outpatients with panic disorder and agoraphobia (PDA) and 63 with obsessive-compulsive disorder (OCD) was examined. Trained interviewers used the Structured Clinical Interview for DSM-II...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1053/comp.2001.19746
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVES:Despite inclusion of adolescent insanity-a concept proposed by Thomas Clouston in late XIX century-into the broader nosological entity of dementia praecox, the uniqueness of early psychosis is still discussed. The aim of the current study is the assessment of course and outcome in the large sample of early-o...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2014.03.013
更新日期：2014-07-01 00:00:00
abstract：:We hypothesized that communication disturbances in the form of unclear linguistic references in schizophrenia are associated with excess-related pathophysiologic processes in some individuals and deficit-related processes in others. We divided a sample of 28 acutely ill schizophrenic inpatients into two groups: those ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(95)90079-b
更新日期：1995-05-01 00:00:00
abstract：:This study investigated the presence of obsessive-compulsive personality disorder (OCPD) in a group of 277 patients (88 with obsessive-compulsive disorder [OCD], 58 with major depressive disorder [MDD], and 131 with panic disorder [Panic]) to test the specificity of the relationship between OCPD and OCD. OCPD is stati...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(97)90051-1
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVE:We hypothesized that subjects with obsessive-compulsive disorder (OCD) who received extended-release fluvoxamine (fluvoxamine ER) in a 12-week placebo-controlled trial would exhibit improvements in psychosocial domains of health-related quality of life (HRQOL) and that additional improvements would occur afte...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.comppsych.2009.10.001
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Kleptomania is characterized by repetitive stealing and has severe consequences for patients. Stigma, a lack of standardized therapy and a limited number of assessment tools hinder advances in treatment. This study provides preliminary data on the Portuguese-language version of the Kleptomania Symptom Assess...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2014.09.013
更新日期：2015-01-01 00:00:00
abstract：:Phenomenological, biological, genetic, treatment-response, and outcome data support a link between schizotypal personality disorder (SPD) and schizophrenia. Furthermore, SPD and normal schizotypy also seem connected, although the relationship can at times be ambiguous. In this regard, this study was conducted to test ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(98)90073-6
更新日期：1998-05-01 00:00:00
abstract：:Previous studies of cognitive functioning in bipolar disorder generally indicate that a more severe course of illness is associated with greater cognitive impairment. In particular, a history of greater number and longer duration of mood episodes predicts enduring cognitive deficits in euthymic patients. Shifting the ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2008.09.005
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVE:The present study aims to provide a comprehensive profile of the primary family caregivers of schizophrenia individuals in rural China. METHOD:A cross-sectional study was conducted with a sample of 327 primary family caregivers of schizophrenia individuals recruited through a one-stage cluster sampling in Ni...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2018.04.002
更新日期：2018-07-01 00:00:00
abstract：:It is becoming increasingly recognized that one third to one half of children diagnosed as having attention deficit/hyperactivity disorder (ADHD) continue to exhibit symptoms of the disorder into adulthood. The nature of the clinical picture is not well understood by a substantial number of clinicians. The purpose of ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(90)90026-o
更新日期：1990-09-01 00:00:00
abstract：:The Axis I phenomenology of 50 outpatients meeting both Diagnostic Interview for Borderlines (DIB) and DSM-III criteria for Borderline Personality Disorder (BPD), 29 outpatients meeting DSM-III criteria for Antisocial Personality Disorder (APD), and 26 outpatients meeting DSM-III criteria for Dsythymic Disorder as wel...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(89)90067-9
更新日期：1989-03-01 00:00:00
abstract：:A clinical chart-review study of the Cluster B personality disorders (PDs) was conducted to evaluate the specificity of DSM-IV criteria for the Antisocial Personality Disorder (ANPD), Borderline Personality Disorder (BPD), and Narcissistic Personality Disorder (NPD). Eight-six outpatients meeting DSM-IV criteria for a...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(98)90036-0
更新日期：1998-09-01 00:00:00
abstract：:Age-specific suicide rates in the United States between 1951 and 1988 were shown in cohort, cross-sectional, and age group formats. Despite considerable variation among women and younger and older men, suicide rates among 40- to 44-year-old men have remained stable. Since suicide is strongly influenced by psychosocial...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(96)90039-5
更新日期：1996-05-01 00:00:00
abstract：BACKGROUND:Knowledge of risk factors is essential for developing strategies that prevent or minimise transitions from mild cognitive impairment (MCI) to Alzheimer's disease (AD) and death. The aim of this study was to assess risk factors for progression to AD and death among Chinese individuals with cognitive impairmen...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2017.07.003
更新日期：2017-10-01 00:00:00
abstract：:Obsessive compulsive symptoms are commonly reported in those with schizophrenia. Clozapine has previously been reported to induce, aggravate and alleviate these symptoms. It is unclear if these are similar to the symptoms experienced by those with obsessive compulsive disorder. This study describes the obsessive compu...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2013.09.001
更新日期：2014-01-01 00:00:00
