Cognitive performance and basic symptoms in first-degree relatives of schizophrenic patients.

Abstract:

:The aim of the present study was to examine cognitive performance and basic symptoms (BS) in the relatives of schizophrenic patients. The experimental sample comprised 24 first-degree relatives of patients. Each relative was matched to one control. Cognitive tests were: Continuous Performance Test (CPT), N-Back Working Memory Test (N-BACK), Negative Priming Test (NPT), and Span of Apprehension Test (SPAN). The Basic Symptoms Questionnaire (FBF) was used to measure subjective disturbances. The relatives showed only slightly worse cognitive performance than the controls, especially in the tasks with greater cognitive processing load. The relatives also revealed more BS than the controls in the domain of thought, attention, memory, language, and visual representation. Only CPT performance was hardly associated with BS. The negative correlation between FBF and CPT was strongly evident in the relatives with poorer processing capacity. This finding suggests that the BS are associated with sustained attention performance. Future research is needed to clarify whether BS are related to other cognitive domains.

journal_name

Compr Psychiatry

journal_title

Comprehensive psychiatry

authors

Bove EA

doi

10.1016/j.comppsych.2008.01.001

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

321-9

issue

4

eissn

0010-440X

issn

1532-8384

pii

S0010-440X(08)00007-2

journal_volume

49

pub_type

杂志文章,评审
  • Characteristics of Chinese rural young suicides: who did not have a strong intent to die.

    abstract:BACKGROUND:In exploration of the risk factors of the Chinese rural young suicide, previous researchers found low prevalence of mental problems, high degree of impulsivity, and great proportion of lethal pesticide consumption. It noticed that some of the young suicides in rural China did not intend to die from the suici...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2014.11.019

    authors: Sun L,Zhang J

    更新日期:2015-02-01 00:00:00

  • Skin picking and trichotillomania in adults with obsessive-compulsive disorder.

    abstract::The objective of this study was to compare patients with obsessive-compulsive disorder (OCD) associated with pathologic skin picking (PSP) and/or trichotillomania, and patients with OCD without such comorbidities, for demographic and clinical characteristics. We assessed 901 individuals with a primary diagnosis of OCD...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.comppsych.2011.06.008

    authors: Lovato L,Ferrão YA,Stein DJ,Shavitt RG,Fontenelle LF,Vivan A,Miguel EC,Cordioli AV

    更新日期:2012-07-01 00:00:00

  • Pretreatment outcome indicators in an eating disorder outpatient group: the effects of self-esteem, personality disorders and dissociation.

    abstract:OBJECTIVE:The prognosis for eating disorders (ED) is unsatisfactory, and the literature about outcome indicators is controversial. The present study evaluates the roles of self-esteem, personality disorders (PD), and dissociation as outcome predictors. METHOD:Fifty-seven ED outpatients were recruited from a population...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2013.03.024

    authors: La Mela C,Maglietta M,Lucarelli S,Mori S,Sassaroli S

    更新日期:2013-10-01 00:00:00

  • Coercion and informed consent in research involving prisoners.

    abstract::Prison-based research has been limited due to concern that prisoners may represent a vulnerable population secondary to possible coercion and limited capacity for voluntary informed consent. This study was designed to assess decisional capacity and susceptibility to coercion in prison research subjects. Subjects were ...

    journal_title:Comprehensive psychiatry

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.comppsych.2003.09.009

    authors: Moser DJ,Arndt S,Kanz JE,Benjamin ML,Bayless JD,Reese RL,Paulsen JS,Flaum MA

    更新日期:2004-01-01 00:00:00

  • Anorexia nervosa associated with Klinefelter's syndrome.

    abstract::A second case of anorexia nervosa associated with Klinefelter's syndrome is described. Gender identity problems were thought to have been significant in this adolescent. ...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/0010-440x(91)90079-r

    authors: el-Badri SM,Lewis MA

    更新日期:1991-07-01 00:00:00

  • French views on positive and negative symptoms: a conceptual history.

    abstract::The history of the positive/negative terminology, as applied to psychiatric symptoms, can be divided into an early period of original meanings, a second one of French elaboration, and the current revival. This report addresses issues concerning the meaning, referent, and nature of the link between the positive and the...

    journal_title:Comprehensive psychiatry

    pub_type: 历史文章,杂志文章

    doi:10.1016/0010-440x(91)90016-6

    authors: Berrios GE

    更新日期:1991-09-01 00:00:00

  • Gender differences in the trends and correlates of major depressive episodes among juvenile offenders in the United States.

    abstract:PURPOSE:Although it is well-established that juvenile offenders are at an elevated risk for depression and that, within this group, females have the highest risk, little is known regarding the trends in the prevalence of depression among juvenile offenders in the United States. In the present study, we systematically e...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2017.09.005

    authors: Holzer KJ,Oh S,Salas-Wright CP,Vaughn MG,Landess J

    更新日期:2018-01-01 00:00:00

  • Pathological gambling: relationship to obesity, self-reported chronic medical conditions, poor lifestyle choices, and impaired quality of life.

    abstract:BACKGROUND:Pathological gambling (PG) is an important public health problem that is prevalent, costly to society, and associated with substance misuse, depression, domestic violence, crime, and suicide. Despite these challenges, little is known about the physical health and medical correlates of PG. The goal of this pr...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2012.07.001

    authors: Black DW,Shaw M,McCormick B,Allen J

    更新日期:2013-02-01 00:00:00

  • Subjective experiences in schizophrenia: a critical review.

    abstract::The current status of subjective experiences in schizophrenia is examined. Subjective experiences are very frequent disorders in schizophrenic patients, and their study has been largely neglected. Recently, a number of scales that evaluate subjective experiences have been published, and although the psychometric prope...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/0010-440x(94)90192-9

    authors: Peralta V,Cuesta MJ

    更新日期:1994-05-01 00:00:00

  • Neurosurgical treatment of Tourette's syndrome: a critical review.

    abstract::Some patients with Tourette's syndrome (TS) remain disabled despite conventional treatment. Recently, neurosurgical procedures have been reported to be potentially effective interventions for such intractable cases. Clinicians are now being asked to make recommendations to patients about these candidate operations. Th...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/s0010-440x(95)90109-4

    authors: Rauch SL,Baer L,Cosgrove GR,Jenike MA

    更新日期:1995-03-01 00:00:00

  • Is alexithymia linked with marital satisfaction or attachment to the partner? A study in a pregnancy cohort of parents-to-be.

    abstract:OBJECTIVE:To investigate possible associations of alexithymia with marital satisfaction and mutual attachment between the partners in a group of parents-to-be during pregnancy. METHODS:The present study was conducted in a pregnancy cohort. Cross-sectional data were available for 151 mothers and 106 fathers, and altoge...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2014.03.019

    authors: Karukivi M,Tolvanen M,Karlsson L,Karlsson H

    更新日期:2014-07-01 00:00:00

  • Subjective experience and subjective response to neuroleptics in schizophrenia.

    abstract::Although several studies have addressed the issue of the relationship between the subjective response to neuroleptics and drug compliance, very little attention has been given to the study of the subjective experience of psychosis and drug attitudes. The present study was therefore undertaken to examine the relationsh...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1053/comp.2000.16566

    authors: Rossi A,Arduini L,Stratta P,Pallanti S

    更新日期:2000-11-01 00:00:00

  • Types of childhood trauma and spirituality in adult patients with depressive disorders.

    abstract:OBJECTIVE:The aim of this study was to investigate the differences in spirituality among adult patients with depressive disorders, who had suffered various types of abuse or neglect in childhood. METHODS:A total of 305 outpatients diagnosed with depressive disorders completed questionnaires on socio-demographic variab...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2016.04.003

    authors: Song JM,Min JA,Huh HJ,Chae JH

    更新日期:2016-08-01 00:00:00

  • Clinical features of children and adolescents with obsessive-compulsive disorder and hoarding symptoms.

    abstract:OBJECTIVE:This study was conducted to examine whether pediatric patients with obsessive-compulsive disorder (OCD) and hoarding symptoms differed in terms of clinical characteristics from pediatric OCD patients without hoarding symptoms. METHOD:Eighty children and adolescents with OCD (range, 7-17 years) completed clin...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2007.03.001

    authors: Storch EA,Lack CW,Merlo LJ,Geffken GR,Jacob ML,Murphy TK,Goodman WK

    更新日期:2007-07-01 00:00:00

  • Assessing alexithymia and emotional awareness: relations between measures in a German non-clinical sample.

    abstract::The aim of this study was to evaluate psychometric properties and relations between two different methods of measuring alexithymia and one measure of emotional awareness in a German non-clinical sample. The 20-Item Toronto Alexithymia Scale (TAS-20), the Toronto Structured Interview for Alexithymia (TSIA), and the Lev...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2013.12.013

    authors: Lichev V,Rufer M,Rosenberg N,Ihme K,Grabe HJ,Kugel H,Donges US,Kersting A,Suslow T

    更新日期:2014-05-01 00:00:00

  • Orgasmic dysfunction among Malay diabetic women in Malaysia.

    abstract:OBJECTIVES:The present study aimed to determine the prevalence and associated factors of orgasmic dysfunction among Malay women with type 2 diabetes mellitus in Malaysia. METHODS:This cross-sectional study involved 347 women (174 non diabetic and 173 diabetic subjects) who attended the diabetic clinic in a university ...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2013.03.009

    authors: Ismail AH,Baw R,Sidi H,Guan NC,Midin M,Nik Jaafar NR,Das S,Manaf MR

    更新日期:2014-01-01 00:00:00

  • The high prevalence of "soft" bipolar (II) features in atypical depression.

    abstract::Seventy-two percent of 86 major depressive patients with atypical features as defined by the DSM-IV and evaluated systematically were found to meet our criteria for bipolar II and related "soft" bipolar disorders; nearly 60% had antecedent cyclothymic or hyperthymic temperaments. The family history for bipolar disorde...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/s0010-440x(98)90080-3

    authors: Perugi G,Akiskal HS,Lattanzi L,Cecconi D,Mastrocinque C,Patronelli A,Vignoli S,Bemi E

    更新日期:1998-03-01 00:00:00

  • Validation of a Greek adaptation of the 20-item Toronto Alexithymia Scale.

    abstract:BACKGROUND:The purpose of the current investigation was (1) to test whether the 3-factor structure of the 20-item Toronto Alexithymia Scale (TAS-20) corresponding to the theoretical conceptualization of the alexithymia construct could be recovered in a Greek translation of the scale (the TAS-20-G), (2) to assess if a 3...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2009.09.005

    authors: Tsaousis I,Taylor G,Quilty L,Georgiades S,Stavrogiannopoulos M,Bagby RM

    更新日期:2010-07-01 00:00:00

  • Insight into illness in schizophrenia.

    abstract::Lack of insight of patients with schizophrenia into various aspects of their illness and treatment is an important clinical issue. Poor insight has been reported to be associated with neurocognitive deficits, particularly in the frontal and parietal functions. The aim of this study was to examine relationships between...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2004.11.002

    authors: Goodman C,Knoll G,Isakov V,Silver H

    更新日期:2005-07-01 00:00:00

  • Psychometric properties of the Temperament and Character Inventory-Revised (TCI-R) in Czech adolescent sample.

    abstract::The psychometric properties of the TCI-R method were investigated in a cohort of 15-year-old adolescents (n = 787). This is the lowest recommended age for using the adult version of the method. A factor analysis of the temperament and character scales was carried out on the basis of Principal Component Analysis with V...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2011.01.008

    authors: Snopek M,Hublova V,Porubanova M,Blatny M

    更新日期:2012-01-01 00:00:00

  • Subjective cognitive dysfunction in first-episode and chronic schizophrenic patients.

    abstract::Previous studies indicate that first-episode and chronic schizophrenic patients do not differ regarding neuropsychological performance as assessed with standard cognitive tasks. For the present study, it was investigated whether first-episode and chronic schizophrenics report similar subjective cognitive deficits. The...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1053/comp.2001.23144

    authors: Moritz S,Lambert M,Andresen B,Böthern A,Naber D,Krausz M

    更新日期:2001-05-01 00:00:00

  • Negative symptoms are associated with lower autonomous motivation towards physical activity in people with schizophrenia.

    abstract:OBJECTIVE:This cross-sectional study examined the association between psychiatric symptoms and motivation for physical activity within the self-determination theory (SDT) framework in people with schizophrenia. METHOD:Over a 4-month period, 55 (17♀) inpatients with a DSM-V diagnosis of schizophrenia were assessed with...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2014.10.007

    authors: Vancampfort D,De Hert M,Stubbs B,Ward PB,Rosenbaum S,Soundy A,Probst M

    更新日期:2015-01-01 00:00:00

  • Nonresponse to clozapine and premorbid functioning in treatment of refractory schizophrenia.

    abstract:INTRODUCTION:It is recognized that early treatment can improve outcomes and generally improve recovery potential for those with schizophrenia. Data suggest that poor premorbid functioning has been found to be related to more severe symptoms and poor antipsychotic response; however, little is known about premorbid funct...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2009.07.003

    authors: Kelly DL,Feldman S,Boggs DL,Gale E,Conley RR

    更新日期:2010-05-01 00:00:00

  • Personality dimensions and criminal arrest.

    abstract::Previous studies have implicated antisocial personality disorder in criminal behavior, but little is known about the association between "normal" personality dimensions and arrest. We investigated the relationships between these personality dimensions and prior arrest in a sample of adults participating in a longitudi...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2004.03.013

    authors: Samuels J,Bienvenu OJ,Cullen B,Costa PT Jr,Eaton WW,Nestadt G

    更新日期:2004-07-01 00:00:00

  • Body image in patients with mental disorders: Characteristics, associations with diagnosis and treatment outcome.

    abstract:OBJECTIVE:Despite the increasing recognition in clinical practice of body image problems in other than appearance related mental disorders, the question remains how aspects of body image are affected in different disorders. The aim of this study was to measure body image in patients with a variety of mental disorders a...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2017.01.004

    authors: Scheffers M,van Busschbach JT,Bosscher RJ,Aerts LC,Wiersma D,Schoevers RA

    更新日期:2017-04-01 00:00:00

  • Personality profiles of patients with dissociative trance disorder in Singapore.

    abstract::This report studies the personality of individuals who suffer from dissociative trance disorder and examines whether the personality profiles could predict the individual's frequency of trance states. A total of 58 cases were given the Eysenck Personality Questionnaire (EPQ) and their personal information harvested fr...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1053/comp.2002.30808

    authors: Ng BY,Yap AK,Su A,Lim D,Ong SH

    更新日期:2002-03-01 00:00:00

  • Life satisfaction and suicidal attempts among persons with schizophrenia.

    abstract::The relationship between subjective quality of life (QOL) and suicide attempts in patients with schizophrenia has been understudied. The current study tested the hypothesis that QOL is negatively associated with a history of suicidality of patients with schizophrenia. QOL, as measured by the Quality of Life Enjoyment ...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/S0010-440X(03)00146-9

    authors: Ponizovsky AM,Grinshpoon A,Levav I,Ritsner MS

    更新日期:2003-11-01 00:00:00

  • Eating disorders and eating pathology in young adult and adult patients with ESSENCE.

    abstract:BACKGROUND:Little is known about the prevalence and incidence of traditional eating disorders (EDs, e.g., anorexia nervosa (AN), bulimia nervosa and binge eating disorder (BED)) in individuals with childhood onset neuropsychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD) and autism spectrum ...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2015.12.009

    authors: Karjalainen L,Gillberg C,Råstam M,Wentz E

    更新日期:2016-04-01 00:00:00

  • Involuntary social cue integration in patients with obsessive compulsive disorder.

    abstract:OBJECTIVE:Patients with obsessive compulsive disorder (OCD) have inferior social functioning compared to healthy controls, but the exact nature of these social deficits, and the underpinning mechanisms, are unknown. We sought to investigate social functioning in patients with OCD by measuring their involuntary/spontane...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2013.08.007

    authors: Tumkaya S,Karadag F,Jellema T,Oguzhanoglu NK,Ozdel O,Atesci FC,Varma G

    更新日期:2014-01-01 00:00:00

  • The neuroethological approach to obsessive-compulsive disorder.

    abstract::Advances in the neurobiology of obsessive-compulsive disorder (OCD) have raised the possibility that animal models in general and neuroethological models in particular may be useful in understanding and investigating this illness. One neuroethologically oriented model is that of canine acral lick dermatitis. In this r...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/0010-440x(92)90053-s

    authors: Stein DJ,Shoulberg N,Helton K,Hollander E

    更新日期:1992-07-01 00:00:00