Abstract：
:Lack of insight of patients with schizophrenia into various aspects of their illness and treatment is an important clinical issue. Poor insight has been reported to be associated with neurocognitive deficits, particularly in the frontal and parietal functions. The aim of this study was to examine relationships between insight and cognitive and emotional function in patients with schizophrenia. Thirty-five male forensic patients suffering from chronic schizophrenia participated. The Scale for the Assessment of Unawareness of Mental Disorder was used to assess insight. Neuropsychological function was assessed with a comprehensive battery of tests. Clinical state was also assessed. Of 35 patients, 18 (51%) believed that they had a mental disorder. A similar proportion reported awareness of a need for medication and correctly attributed symptoms to illness. Measures of insight showed significant associations with visual object learning, verbal working memory, and identification of facial emotions but not with measures of frontal lobe function. Poorer insight was associated with a higher occurrence of violent events. Our findings support an association between poor insight and cognitive impairment in patients with chronic schizophrenia but suggest that the relationship may not specifically involve frontal lobe dysfunction.
journal_name
Compr Psychiatryjournal_title
Comprehensive psychiatryauthors
Goodman C,Knoll G,Isakov V,Silver Hdoi
10.1016/j.comppsych.2004.11.002subject
Has Abstractpub_date
2005-07-01 00:00:00pages
284-90issue
4eissn
0010-440Xissn
1532-8384pii
S0010-440X(04)00177-4journal_volume
46pub_type
杂志文章abstract：INTRODUCTION:Dopamine receptor polymorphisms have been associated with specific patterns of novelty seeking (NS) temperamental nature and frontal executive function. In addition, carriers of dopamine receptor type 2 (DRD2)-TaqI A1 have been hypothesized to be potentially vulnerable to addictive behaviors. In the presen...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2008.01.008
更新日期：2008-07-01 00:00:00
abstract：:Demoralization may be viewed as a combination of distress and subjective incompetence. The main problem in demoralization is the sense of incompetence experienced by the demoralized individual; this sense of incompetence results from uncertainty as to the appropriate direction of action. By contrast, the major difficu...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,评审
doi：10.1016/0010-440x(93)90016-w
更新日期：1993-09-01 00:00:00
abstract：:A dysfunction of pursuit eye tracking in psychiatric patients has been well documented, but its cause has not. Recent speculation implicates a pathological disinhibition of saccades in these patients. However, great variability in tracking performance was found among nine normal subjects, and tracking quality improved...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(90)90009-h
更新日期：1990-05-01 00:00:00
abstract：:In this report, a first comprehensive description of the clinical features of patients with organic mood syndrome, depressed type (OMS-D), in a psychiatric hospital population is presented. This description is based on information from 130 OMS-D patients among 14,889 patients who presented for initial evaluation over ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(93)90071-b
更新日期：1993-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to assess the reliability and validity of a Persian translation of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I Disorders (SCID-I) through a multicenter study in a clinical population in Iran. METHOD:The sample con...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2008.04.004
更新日期：2009-01-01 00:00:00
abstract：:Previous studies have implicated antisocial personality disorder in criminal behavior, but little is known about the association between "normal" personality dimensions and arrest. We investigated the relationships between these personality dimensions and prior arrest in a sample of adults participating in a longitudi...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2004.03.013
更新日期：2004-07-01 00:00:00
abstract：BACKGROUND:Knowledge of risk factors is essential for developing strategies that prevent or minimise transitions from mild cognitive impairment (MCI) to Alzheimer's disease (AD) and death. The aim of this study was to assess risk factors for progression to AD and death among Chinese individuals with cognitive impairmen...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2017.07.003
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND:Timely administration/supplementation of a specific serotonin reuptake inhibitor with a second therapeutic agent could improve treatment outcome in patients with major depressive disorder (MDD). The purpose of this study was to identify the optimal time at which to implement supplementation so as to maximize...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.comppsych.2010.04.007
更新日期：2011-01-01 00:00:00
abstract：:Major depression forms the background of upwards of half of all suicides. Women are twice as likely as men to experience major depression, yet women are one fourth as likely as men to take their own lives. Current and past explanations of this paradox are built on androcentric assumptions that women are deficient in s...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,评审
doi：10.1016/s0010-440x(98)90057-8
更新日期：1998-07-01 00:00:00
abstract：OBJECTIVE:The Eating Disorder Inventory (EDI) is used worldwide in research and treatment of eating disorders (EDs). Using the latest version (EDI-3: 91 items), we extracted the best screening items for a diagnosis of anorexia (AN) and bulimia (BN) nervosa. METHOD:A patient sample of 561 women was recruited from an ED...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2013.05.004
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Medical illnesses are highly comorbid with bipolar disorder, but their relationship to illness characteristics has not been previously delineated. METHODS:The incidence of 34 medical conditions and 6 poor prognosis factors (PPFs) was derived from answers to a questionnaire in over 900 outpatients with bipol...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2014.08.050
更新日期：2015-01-01 00:00:00
abstract：:Fifty-one adolescent-onset anorexia nervosa (AN) cases recruited after community screening were compared with 51 age-, sex-, and school-matched cases with regard to personality disorders and autism-spectrum disorders (ASD)/empathy disorders at age 21 years. All 102 cases had originally been examined at a mean age of 1...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(95)90100-a
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:OCD causes impairment in different areas of the patients' quality of life (QoL), such as sociability, family relationships, and occupational performance. The literature has emphasized the relevance of assessing QoL as a critical outcome in mental health studies. AIMS:The aim of this study was to investigate...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2018.07.007
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:Recent studies have suggested that the brain circuitry mediating cue-induced desire for video games is similar to that elicited by cues related to drugs and alcohol. We hypothesized that desire for Internet video games during cue presentation would activate similar brain regions to those that have been linked...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2010.04.004
更新日期：2011-01-01 00:00:00
abstract：:In current psychiatric literature, the received view is that dissociative symptoms originate from aversive childhood events. To a large extent, this view is based on cross-sectional studies that do not rule out a scenario in which dissociative tendencies contribute to self-reports of childhood trauma. In two studies, ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/S0010-440X(03)00149-4
更新日期：2004-01-01 00:00:00
abstract：:Concern within the literature has emerged from time to time arguing the poor validity of self-reported measures in psychopathology, namely, the reporting of psychotic experience. Although it is commonly believed that patients who have had a psychotic episode cannot accurately self-report their experience, very few stu...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/S0010-440X(03)00010-5
更新日期：2003-05-01 00:00:00
abstract：:Studies conducted in the United States and Japan indicate that diabetes mellitus is more common among schizophrenic patients than among the general population. The prevalence of known diabetes was examined in 95 schizophrenic patients aged 45 to 74 years admitted to a long-term care facility in Italy. The overall prev...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(96)90054-1
更新日期：1996-01-01 00:00:00
abstract：OBJECTIVES:To compare quality of life (QoL) in mental health outpatients to non-clinical norms, and examine the associations between QoL and principal diagnosis, number of comorbid Axis I diagnoses, and type of comorbidity. METHODS:Consecutively referred and assessed patients (n = 2024) formed the study sample pool. O...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2010.07.006
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:Most diagnostic interviews depend on recall of past symptoms and may be vulnerable to recall bias. The objective of this study was to describe the epidemiology of major depression using an approach that is less reliant on recall using an assessment scale, the 9-item Brief Patient Health Questionnaire (PHQ-9)...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2008.05.012
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:In exploration of the risk factors of the Chinese rural young suicide, previous researchers found low prevalence of mental problems, high degree of impulsivity, and great proportion of lethal pesticide consumption. It noticed that some of the young suicides in rural China did not intend to die from the suici...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2014.11.019
更新日期：2015-02-01 00:00:00
abstract：:This study measured self-reported aggression, hostility, and anger in Vietnam combat veterans with (n = 27) and without (n = 15) posttraumatic stress disorder (PTSD). On the Buss-Durkee Hostility Inventory, Past Feelings and Acts of Violence Scale, Episodic Dyscontrol Scale, and State-Trait Anger Expression Inventory ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(94)90278-x
更新日期：1994-09-01 00:00:00
abstract：:The relationship between subjective quality of life (QOL) and suicide attempts in patients with schizophrenia has been understudied. The current study tested the hypothesis that QOL is negatively associated with a history of suicidality of patients with schizophrenia. QOL, as measured by the Quality of Life Enjoyment ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/S0010-440X(03)00146-9
更新日期：2003-11-01 00:00:00
abstract：BACKGROUND:Recent studies suggest that parents' awareness of their offspring's schizophrenia could influence their offspring's insight. Low patient insight is linked to impairment of specific cognitive abilities, and biological parents of schizophrenia patients have impaired capacities in these same domains. However, l...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2017.02.013
更新日期：2017-07-01 00:00:00
abstract：:The Defense Style Questionnaire (DSQ) assesses defensive behavior by empirically evaluating conscious derivatives of defense and coping mechanisms in everyday life. It was developed on the assumption that defenses can be ordered along a maturity-immaturity continuum and tend to group into clusters, or defensive styles...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2004.07.012
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:The goal of our study was to investigate the impact of dysthymic disorder (DD), a form of chronic depression, on naturalistic outcome in individuals with personality disorders (PDs). METHOD:The Collaborative Longitudinal Personality Disorders Study is a cohort initially including 573 subjects with 4 targeted...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2009.11.002
更新日期：2010-09-01 00:00:00
abstract：:Recent studies have suggested an association between childhood physical and sexual abuse and adult dissociative experiences. The purpose of this study was to determine the relationship of both childhood and adult-onset abuse and their characteristics for adult dissociative symptoms. One hundred forty-four psychiatric ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(96)90005-x
更新日期：1996-07-01 00:00:00
abstract：BACKGROUND:Tonic immobility is an involuntary response to inescapable life-threatening events. Peritraumatic tonic immobility has been reported in convenience samples of female victims of sexual assault and in mixed-gender victims of different types of trauma. This study evaluated peritraumatic tonic immobility in a re...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2015.04.001
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:The Dark Triad (DT) describes a set of three closely related personality traits, Machiavellianism, narcissism, and psychopathy. The aim of this study was to examine the associations between DT traits, sleep disturbances, anxiety sensitivity and intolerance of uncertainty. METHOD:A total of 341 adults (M=29y...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2016.03.012
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:The purpose of the current investigation was (1) to test whether the 3-factor structure of the 20-item Toronto Alexithymia Scale (TAS-20) corresponding to the theoretical conceptualization of the alexithymia construct could be recovered in a Greek translation of the scale (the TAS-20-G), (2) to assess if a 3...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2009.09.005
更新日期：2010-07-01 00:00:00
abstract：:From a total sample of 1,448 psychiatric outpatients, 175 (12.1%) received a diagnosis of a somatoform disorder according to DSM-III-R criteria. One hundred twenty-two (70%) of these patients had another current axis I diagnosis, and this rate increased to 79% (139 of 175) when lifetime psychiatric diagnoses were reco...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(99)90131-1
更新日期：1999-07-01 00:00:00
