Psychiatric diagnosis and quality of life: the additional burden of psychiatric comorbidity.

Abstract:

OBJECTIVES:To compare quality of life (QoL) in mental health outpatients to non-clinical norms, and examine the associations between QoL and principal diagnosis, number of comorbid Axis I diagnoses, and type of comorbidity. METHODS:Consecutively referred and assessed patients (n = 2024) formed the study sample pool. Of these, 1486 individuals who had completed a QoL instrument at intake and had a principal diagnosis amenable to comparison by group analysis were included in the study. Principal diagnoses were unipolar mood disorder (n = 687), eating disorder (n = 226), bipolar disorder (n = 165), social anxiety disorder (n = 165), generalized anxiety disorder (n = 125), and panic disorder (n = 118). QoL for psychiatric groups was compared to non-clinical norms using a valid and reliable measure. RESULTS:QoL was significantly impaired in all psychiatric groups compared to nonclinical norms. There was a significant interaction between principal diagnosis and number of comorbid Axis I disorders, controlling for age, sex, marital status, employment, and years of school. The addition of one comorbidity significantly attenuated QoL in social anxiety disorder, panic disorder, and bipolar disorder. For all other conditions, a significant loss in QoL occurred with two or more comorbidities. Axis I depressive and anxiety comorbidity significantly attenuated QoL across all diagnostic groups. CONCLUSIONS:QoL is significantly impaired in psychiatric outpatients and diagnostic groups vary in the extent to which they experience additional QoL burden with increasing comorbidities.

journal_name

Compr Psychiatry

journal_title

Comprehensive psychiatry

authors

Watson HJ,Swan A,Nathan PR

doi

10.1016/j.comppsych.2010.07.006

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

265-72

issue

3

eissn

0010-440X

issn

1532-8384

pii

S0010-440X(10)00097-0

journal_volume

52

pub_type

杂志文章
  • Types of panic attacks and their association with psychiatric disorder and physical illness.

    abstract::The differentiation of three types of panic attacks is proposed to be significant for understanding the course and etiology of panic and other psychiatric disorders and physical illnesses. The present investigation is based on longitudinal data from the Epidemiologic Catchment Area (ECA) Study of 1980 to 1981 and its ...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/s0010-440x(99)90092-5

    authors: Bovasso G,Eaton W

    更新日期:1999-11-01 00:00:00

  • Relationship of Internet addiction with cognitive style, personality, and depression in university students.

    abstract:BACKGROUND:The aim of the study was to investigate the relationship of dysfunctional attitudes, self-esteem, personality, and depression with Internet addiction in university students. METHODS:A total of 720 university students participated in the study in Bülent Ecevit University English Preparatory School which offe...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2014.04.025

    authors: Senormancı O,Saraçlı O,Atasoy N,Senormancı G,Koktürk F,Atik L

    更新日期:2014-08-01 00:00:00

  • Temperament and character in patients with systemic lupus erythematosus.

    abstract:BACKGROUND:In addition to identified neuropsychiatric characteristic of systemic lupus erythematosus (SLE), changes in personality seem to occur in patients with SLE. Even in absence of an axis I psychiatric diagnosis, personality variations play important role in general wellbeing of these patients. This study investi...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2017.09.007

    authors: Mani A,Rostami A,Aflaki E,Ravanfar P

    更新日期:2018-01-01 00:00:00

  • Obsessive compulsive symptoms in patients with Schizophrenia on Clozapine and with Obsessive Compulsive disorder: a comparison study.

    abstract::Obsessive compulsive symptoms are commonly reported in those with schizophrenia. Clozapine has previously been reported to induce, aggravate and alleviate these symptoms. It is unclear if these are similar to the symptoms experienced by those with obsessive compulsive disorder. This study describes the obsessive compu...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2013.09.001

    authors: Doyle M,Chorcorain AN,Griffith E,Trimble T,O'Callaghan E

    更新日期:2014-01-01 00:00:00

  • Exploring whether genetic differences between siblings explain sibling differences in criminal justice outcomes.

    abstract::Research has revealed that despite many similarities, siblings raised within the same household have also been found to be markedly different from one another. Behavioral differences between siblings have been primarily attributed to differential exposure to a wide variety of environmental influences. The potential ro...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2013.06.002

    authors: Schwartz JA,Beaver KM

    更新日期:2014-01-01 00:00:00

  • A Persian translation of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition: psychometric properties.

    abstract:OBJECTIVE:The aim of this study is to assess the reliability and validity of a Persian translation of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I Disorders (SCID-I) through a multicenter study in a clinical population in Iran. METHOD:The sample con...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2008.04.004

    authors: Sharifi V,Assadi SM,Mohammadi MR,Amini H,Kaviani H,Semnani Y,Shabani A,Shahrivar Z,Davari-Ashtiani R,Shooshtari MH,Seddigh A,Jalali M

    更新日期:2009-01-01 00:00:00

  • The development, use, and reliability of the brief psychiatric rating scale (nursing modification)--an assessment procedure for the nursing team in clinical and research settings.

    abstract::The role of nursing staff in the systematic rating of psychopathology has been explored in a small number of studies in recent years. Nurses are uniquely placed to carry out relatively continuous observations of high validity which are sensitive to change, yet on the basis of the limited data available, some doubts re...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/0010-440x(88)90078-8

    authors: McGorry PD,Goodwin RJ,Stuart GW

    更新日期:1988-11-01 00:00:00

  • Impact of ADHD symptoms on clinical and cognitive aspects of problem gambling.

    abstract:BACKGROUND:Problem gambling is common across cultures, and has been conceptualized in terms of impulsivity. While elevated rates of attention deficit hyperactivity disorder (ADHD) have been observed in problem gamblers, the relationship between these two conditions, and other dissociable forms of impulsivity, has recei...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2014.10.013

    authors: Chamberlain SR,Derbyshire K,Leppink E,Grant JE

    更新日期:2015-02-01 00:00:00

  • The validation study and application of stratum-specific likelihood ratios in the Chinese version of SPAN.

    abstract::The Davidson Trauma Scale (DTS) is a validated self-rating scale used in the diagnosis of post-traumatic stress disorder (PTSD). A shorter version of the DTS was developed to serve as a diagnostic screening tool. A four-item scale, the SPAN (named for its principal four items: Startle, Physiological arousal, Anger, an...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1053/comp.2003.50013

    authors: Chen CH,Shen WW,Tan HK,Chou JY,Lu ML

    更新日期:2003-01-01 00:00:00

  • Frequency of reporting of adverse events in randomized controlled trials of psychotherapy vs. psychopharmacotherapy.

    abstract:BACKGROUND:Psychopharmacology and psychotherapy are the two main therapies in mental health. It is common practice to consider adverse events (AEs) of medications, but it's not clear this occurs with psychotherapy. AIM:This study investigates the frequency with which reports of AEs occur in clinical trials using eithe...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.comppsych.2014.01.001

    authors: Vaughan B,Goldstein MH,Alikakos M,Cohen LJ,Serby MJ

    更新日期:2014-05-01 00:00:00

  • Social connectedness, stressful life events, and self-injurious thoughts and behaviors among young adults.

    abstract:OBJECTIVES:Preventing self-injurious thoughts and behaviors (SITBs) is particularly challenging on commuter campuses, given lower social cohesion and higher levels of stress than among traditional college populations. The present study examined the relationship between stressful life events (SLEs) and risk for differen...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2017.09.008

    authors: Macrynikola N,Miranda R,Soffer A

    更新日期:2018-01-01 00:00:00

  • Emotion perception, non-social cognition and symptoms as predictors of theory of mind in schizophrenia.

    abstract:BACKGROUND:Theory of mind (ToM) can be divided into cognitive and affective ToM, and a distinction can be made between overmentalizing and undermentalizing errors. Research has shown that ToM in schizophrenia is associated with non-social and social cognition, and with clinical symptoms. In this study, we investigate c...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2018.05.002

    authors: Vaskinn A,Andersson S,Østefjells T,Andreassen OA,Sundet K

    更新日期:2018-08-01 00:00:00

  • Clinicians' conflicting emotional responses to high suicide-risk patients-Association with short-term suicide behaviors: A prospective pilot study.

    abstract:BACKGROUND:Clinician's emotional responses to patients have been recognized as potentially relating to treatment outcome, however they have received little attention in the literature on suicide risk. We examine the relationship between a novel targeted measure of clinicians' emotional responses to high-risk psychiatri...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2017.03.013

    authors: Yaseen ZS,Galynker II,Cohen LJ,Briggs J

    更新日期:2017-07-01 00:00:00

  • The relationship between temperament and character in conversion disorder and comorbid depression.

    abstract:AIMS:The aim of this study was to compare conversion disorder patients with healthy controls in terms of temperament and character, and to determine the effect of these characteristics on comorbid depression, based on the idea that conversion disorder patients may have distinctive temperament and character qualities. ...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2012.10.007

    authors: Erten E,Yenilmez Y,Fistikci N,Saatcioglu O

    更新日期:2013-05-01 00:00:00

  • Serum brain-derived neurotrophic factor levels and psychotic symptoms in heroin dependence.

    abstract:OBJECTIVES:Psychotic symptoms are commonly observed among heroin users. Low serum brain-derived neurotrophic factor (BDNF) levels have been reported in schizophrenia and psychosis; however, studies assessing the relationship between serum BDNF levels and psychotic symptoms in heroin dependence are lacking. METHOD:A to...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2015.06.008

    authors: Han B,Zhang XY,Wang DY,Ren WW,Gu YY,Zhu L,Chang YL,Wang LP,Wu CW,Jin QQ,Chen C,Lyu DZ,Zhao JY,Shao B,He JC

    更新日期:2015-10-01 00:00:00

  • The cognitive structure of higher functioning autism and schizophrenia: a comparative study.

    abstract::The purpose of this study was to examine whether performance on a standard cognitive test-battery can be used to clearly separate higher functioning autism from schizophrenia. Revised Wechsler Intelligence Scale for Children (WISC-R) or Adults (WAIS-R) profiles of 20 autistic and 20 schizophrenic adolescent young adul...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1053/comp.2002.33490

    authors: Bölte S,Rudolf L,Poustka F

    更新日期:2002-07-01 00:00:00

  • Mental health of single fathers living in an urban community in South Korea.

    abstract:OBJECTIVE:The aims of this study were to understand the mental health of single fathers relative to married fathers as the population of single fathers continues to increase and to use the resultant data for the establishment of public health policies. METHODS:We evaluated the mental health of 58 single fathers and 25...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2014.09.012

    authors: Kong KA,Kim SI

    更新日期:2015-01-01 00:00:00

  • Separation anxiety in adulthood: dimensional or categorical?

    abstract::Recent evidence suggests that a clinical form of separation anxiety can be observed in adults. An important question of relevance to defining the construct of adult separation anxiety is whether there is discontinuity between that constellation and other forms of anxiety. In the present study, 2 taxometric procedures ...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2007.05.011

    authors: Silove D,Slade T,Marnane C,Wagner R,Brooks R,Manicavasagar V

    更新日期:2007-11-01 00:00:00

  • Is a brief self-report version of the Columbia severity scale useful for screening suicidal ideation in Chilean adolescents?

    abstract:BACKGROUND:Given the high rates of suicide in the adolescent population and the reluctance of this population to seek help, developing proactive and effective strategies to timely detect individuals at high risk for suicide in non-clinical contexts is a worldwide recognized need. A series of brief self-report questionn...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2018.11.002

    authors: Núñez D,Arias V,Méndez-Bustos P,Fresno A

    更新日期:2019-01-01 00:00:00

  • Validation of a Greek adaptation of the 20-item Toronto Alexithymia Scale.

    abstract:BACKGROUND:The purpose of the current investigation was (1) to test whether the 3-factor structure of the 20-item Toronto Alexithymia Scale (TAS-20) corresponding to the theoretical conceptualization of the alexithymia construct could be recovered in a Greek translation of the scale (the TAS-20-G), (2) to assess if a 3...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2009.09.005

    authors: Tsaousis I,Taylor G,Quilty L,Georgiades S,Stavrogiannopoulos M,Bagby RM

    更新日期:2010-07-01 00:00:00

  • Population-based prevalence of smoking in psychiatric inpatients: a focus on acute suicide risk and major diagnostic groups.

    abstract:OBJECTIVE:The aim of the study was to define the extent of current and lifetime smoking by diagnostic groups and suicide risk as reason for admission in a geographically defined psychiatric inpatient cohort. DESIGN:The study used a population-based retrospective chart review. METHODS:Smoking status and discharge diag...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2009.01.004

    authors: Lineberry TW,Allen JD,Nash J,Galardy CW

    更新日期:2009-11-01 00:00:00

  • Obsessive-compulsive disorder: its conceptual history in France during the 19th century.

    abstract::Until the 1850s, obsessive-compulsive phenomena were considered to be a variant of the old notion of insanity. Around this time they became a separate disease: first, as a member of the old class of the neuroses; then, briefly, as a variant of the newly formed notion of psychosis; and finally, as a neurosis proper (in...

    journal_title:Comprehensive psychiatry

    pub_type: 历史文章,杂志文章

    doi:10.1016/0010-440x(89)90052-7

    authors: Berrios GE

    更新日期:1989-07-01 00:00:00

  • Does food addiction contribute to excess weight among clinic patients seeking weight reduction? Examination of the Modified Yale Food Addiction Survey.

    abstract:BACKGROUND:Despite controversy surrounding the construct of food addiction, its relationship with obesity and the validity of the Yale Food Addiction Scale (YFAS), have become emerging fields of study. No prior research has examined the prevalence and correlates of food addiction, and validation of the Modified Yale Fo...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2018.03.006

    authors: Masheb RM,Ruser CB,Min KM,Bullock AJ,Dorflinger LM

    更新日期:2018-07-01 00:00:00

  • Correlations of attitudes toward antipsychotic drugs with insight and objective psychopathology in schizophrenia.

    abstract:OBJECTIVE:The aim of this cross-sectional study was to examine the relationships between attitudes toward antipsychotics, insight, and other clinical variables in stable schizophrenia. METHODS:Fifty Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision-(DSM-IV-TR)-diagnosed schizophrenic...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2007.08.013

    authors: Rocca P,Crivelli B,Marino F,Mongini T,Portaleone F,Bogetto F

    更新日期:2008-03-01 00:00:00

  • Other psychiatric disorders among bulimic patients.

    abstract::Clinical experience suggests that bulimia nervosa is a disorder often accompanied by additional psychiatric symptoms. Based on unstructured clinical interviews, 21 additional Axis I and six Axis II diagnoses were assigned to a sample of 30 bulimic women. The Structured Clinic Interview for DSM-III-Patient Version (SCI...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/0010-440x(88)90066-1

    authors: Powers PS,Coovert DL,Brightwell DR,Stevens BA

    更新日期:1988-09-01 00:00:00

  • Subjective experiences in schizophrenia: a critical review.

    abstract::The current status of subjective experiences in schizophrenia is examined. Subjective experiences are very frequent disorders in schizophrenic patients, and their study has been largely neglected. Recently, a number of scales that evaluate subjective experiences have been published, and although the psychometric prope...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/0010-440x(94)90192-9

    authors: Peralta V,Cuesta MJ

    更新日期:1994-05-01 00:00:00

  • Crying behavior and psychiatric disorder in adults: a review.

    abstract::Crying is a common human behavior that is encountered in varied clinical settings. However, its relationship to mood and psychiatric disorders remains unclear. In this report, the relevant literature on the relationship of crying behavior and psychiatric disorders is reviewed. Two clinically distinct types of crying b...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/0010-440x(93)90049-a

    authors: Patel V

    更新日期:1993-05-01 00:00:00

  • The effect of dietary and physical activity pattern on metabolic profile in individuals with schizophrenia: a cross-sectional study.

    abstract:OBJECTIVE:With the rate of obesity on the rise worldwide, individuals with schizophrenia represent a particularly vulnerable population. The aim of this study was to assess the metabolic profile of individuals with schizophrenia in relation to dietary and physical activity habits compared with healthy controls. METHOD...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2012.02.003

    authors: Ratliff JC,Palmese LB,Reutenauer EL,Liskov E,Grilo CM,Tek C

    更新日期:2012-10-01 00:00:00

  • Heterogeneity among depressed outpatients considered to be in remission.

    abstract::More than a decade ago, a consensus panel recommended that remission be defined on the 17-item version of the Hamilton Rating Scale for Depression (HAM-D) as a cutoff of less than 7. Recently, some investigators have suggested that this threshold to define remission may be too high. If true, this means that heterogene...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2006.10.005

    authors: Zimmerman M,Posternak MA,Chelminski I

    更新日期:2007-03-01 00:00:00

  • High impulsivity as a risk factor for the development of internalizing disorders in detained juvenile offenders.

    abstract:BACKGROUND:Whilst impulsivity is most commonly linked to the development of internalizing disorders, high levels of impulsivity, anxiety, and depression have been found in detained juvenile offenders. We therefore sought to determine whether impulsivity is associated with the development of self-reported anxiety or dep...

    journal_title:Comprehensive psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.comppsych.2014.03.022

    authors: Zhou J,Witt K,Chen C,Zhang S,Zhang Y,Qiu C,Cao L,Wang X

    更新日期:2014-07-01 00:00:00