Abstract:
BACKGROUND:Psychopharmacology and psychotherapy are the two main therapies in mental health. It is common practice to consider adverse events (AEs) of medications, but it's not clear this occurs with psychotherapy. AIM:This study investigates the frequency with which reports of AEs occur in clinical trials using either psychopharmacology alone, psychotherapy alone, or combined approaches. METHODS:Forty-five articles of randomized trials published in high-impact journals were chosen from a Medline search, and separated into three groups of 15 articles: pharmacotherapy alone (M), psychotherapy alone (T) and combined studies that looked at the effect of both a psychotherapeutic (CT) and psychopharmacologic (CM) intervention. Criteria for what defines an AE were established and the papers were rated for mentions of AEs in papers as a whole and by each section. RESULTS:The χ(2)-analysis of AE mentions showed significant differences between the four study conditions in terms of each paper as a whole (χ(2):10.1,p<0.018), and by section. Medication (M+CM) and psychotherapy papers (T+CT) were then combined into two groups to compare the odds that one was more likely to mention AEs than the other. Bivariate logistic regression yielded statistically significant odds ratios ranging from 9.33 to 20.99, with medications being far more likely to mention AEs. CONCLUSION:We believe the difference in reports of AEs mirrors the attitudes researchers and providers. It's critical to consider, and standardize the definition of, AEs in psychotherapy, and imperative to identify and address potential AEs in psychotherapy research.
journal_name
Compr Psychiatryjournal_title
Comprehensive psychiatryauthors
Vaughan B,Goldstein MH,Alikakos M,Cohen LJ,Serby MJdoi
10.1016/j.comppsych.2014.01.001subject
Has Abstractpub_date
2014-05-01 00:00:00pages
849-55issue
4eissn
0010-440Xissn
1532-8384pii
S0010-440X(14)00006-6journal_volume
55pub_type
杂志文章,meta分析,评审abstract:BACKGROUND:Although reduced hippocampal volume (HCV) is a common finding in depression, it is unclear whether the structural alterations leading to reduction of HCV are pre-existing risk factors before the onset of clinical symptoms or a cumulative process that begins with the onset of clinical symptoms. The aim of the...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2018.01.004
更新日期:2018-04-01 00:00:00
abstract::Some patients with Tourette's syndrome (TS) remain disabled despite conventional treatment. Recently, neurosurgical procedures have been reported to be potentially effective interventions for such intractable cases. Clinicians are now being asked to make recommendations to patients about these candidate operations. Th...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章,评审
doi:10.1016/s0010-440x(95)90109-4
更新日期:1995-03-01 00:00:00
abstract::The purpose of this study was to develop and test the Talbieh Brief Distress Inventory (TBDI), a 24-item self-report questionnaire that measures psychological distress among immigrants. The TBDI combines items from the Brief Symptom Inventory (BSI) and the Psychiatric Epidemiology Research Interview Demoralization Sca...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(95)90253-8
更新日期:1995-11-01 00:00:00
abstract::In current psychiatric literature, the received view is that dissociative symptoms originate from aversive childhood events. To a large extent, this view is based on cross-sectional studies that do not rule out a scenario in which dissociative tendencies contribute to self-reports of childhood trauma. In two studies, ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/S0010-440X(03)00149-4
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Limited data are available examining the relationship between mental state disorders (mood, anxiety, substance use, eating disorders), their co-occurrence with personality disorder (PD), and quality of life among women. We aimed to investigate these relationships in a sample of women from the community. MET...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2020.152193
更新日期:2020-10-01 00:00:00
abstract:AIMS:To investigate the gender differences in neurocognitive functioning in patients with first-episode schizophrenia (FES) in China. METHODS:A total of 449 Chinese patients with FES (210 males, 239 females) were included in this study. Participants' psychopathology was assessed by the Positive and Negative Syndrome S...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1016/j.comppsych.2019.152132
更新日期:2019-11-01 00:00:00
abstract::As part of an ongoing study of risk factors for unipolar depression in a high-risk group, we have evaluated cognitive variables documented to be abnormal during an episode of depression in adult first-degree relatives of unipolar depressed probands. Asymptomatic relatives with a history of unipolar depression were com...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(89)90042-4
更新日期:1989-05-01 00:00:00
abstract:OBJECTIVE:To examine the factor structure of the 144-item Chinese version of the Temperament and Character Inventory (TCI) and its association with age and gender in a large non-clinical population. METHOD:We recruited 1966 non-clinical participants in China who completed the TCI Chinese version. They were randomly di...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2012.08.003
更新日期:2013-04-01 00:00:00
abstract::People who engage in nonsuicidal self-injury (NSSI) often report high levels of impulsivity. However, results from behavioral tasks measuring impulsivity have been mixed: those with a history of NSSI generally perform comparably to healthy controls. Recent research suggests, however, that people who self-injure have s...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2016.10.011
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Pathologic levels of ritualistic avoidance (also known as active avoidance) are common in the clinical presentation of obsessive-compulsive disorder (OCD). Despite its clinical relevance, there has been little examination of active avoidance as a ritualistic compulsion in adults with OCD. OBJECTIVE:The obje...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2011.03.002
更新日期:2012-02-01 00:00:00
abstract:INTRODUCTION:This study aimed to examine the prevalence of pre-marital sex and its predicting factors among youth trainees undergoing a national skill training programme in the state of Malaysia. METHODS:Participants filled up health screening surveys at the beginning of their training period. A total of 1328 out of 1...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2013.03.008
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Craving for substance use has been added as one of the diagnostic criteria of substance use disorders in DSM-5. However, further research is necessary to examine and expand the clinical potential of craving in the assessment and treatment for heroin users. This study aimed to examine the psychometrics of the...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2015.10.001
更新日期:2016-02-01 00:00:00
abstract::The transition to alcohol dependence is supposed to occur during a critical period that begins with increased drinking and ends with a loss of control. This process may last about 3 to 4 years, and is modified by gender and accelerated by premorbid traits (e.g., novelty-seeking) and comorbid disorders (e.g., dissocial...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(00)80014-0
更新日期:2000-03-01 00:00:00
abstract:AIMS:The aim of this study was to compare conversion disorder patients with healthy controls in terms of temperament and character, and to determine the effect of these characteristics on comorbid depression, based on the idea that conversion disorder patients may have distinctive temperament and character qualities. ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2012.10.007
更新日期:2013-05-01 00:00:00
abstract::Fifty-one adolescent-onset anorexia nervosa (AN) cases recruited after community screening were compared with 51 age-, sex-, and school-matched cases with regard to personality disorders and autism-spectrum disorders (ASD)/empathy disorders at age 21 years. All 102 cases had originally been examined at a mean age of 1...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(95)90100-a
更新日期:1995-01-01 00:00:00
abstract::Exposure to earthquakes has been associated with psychological distress in particular, the development of posttraumatic stress disorder (PTSD). The aims of this study are to estimate the prevalence of PTSD, explore the associated risk factors among survivors 1 year after the Wenchuan earthquake in China, and compare t...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2010.08.002
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:Panic Disorder (PD) and agoraphobia (AG) are frequently comorbid with obsessive-compulsive disorder (OCD), but the correlates of these comorbidities in OCD are fairly unknown. The study aims were to: 1) estimate the prevalence of PD with or without AG (PD), AG without panic (AG) and PD and/or AG (PD/AG) in a ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2013.11.017
更新日期:2014-04-01 00:00:00
abstract::The mental and physical health care issues of medical students are increasingly recognized as both prevalent and complex. Emotional distress, symptoms of mental illness, and maladaptive substance use are widespread and may often be driven by training-related stressors. The data suggest that nearly all medical students...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1053/comp.2000.0410303
更新日期:2000-07-01 00:00:00
abstract::Fire-setting is a serious and costly form of antisocial behavior. Our objective in this study was to examine the prevalence and correlates of intentional fire-setting behavior in the United States. Data were derived from a nationally representative sample of US residents 18 years and older. Structured psychiatric inte...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2009.06.002
更新日期:2010-05-01 00:00:00
abstract::It is widely appreciated that a social stigma surrounds psychiatric illness in contemporary society. Researchers have concentrated on the nature and consequences of psychiatric stigma. Although there exists much work on the social history of mental illness, stigma, per se, has not often been addressed in historical st...
journal_title:Comprehensive psychiatry
pub_type: 历史文章,杂志文章
doi:10.1016/0010-440x(90)90036-r
更新日期:1990-07-01 00:00:00
abstract::We assessed clinicians' practices in the process of personality assessment according to DSM-III axis II criteria. Forty-six clinicians rated personality traits and disorders on two versions of a clinical profile constructed to meet DSM-III axis II diagnoses of histrionic, narcissistic, borderline, and dependent, diffe...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(90)90016-l
更新日期:1990-03-01 00:00:00
abstract:OBJECTIVE:Despite the increasing recognition in clinical practice of body image problems in other than appearance related mental disorders, the question remains how aspects of body image are affected in different disorders. The aim of this study was to measure body image in patients with a variety of mental disorders a...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2017.01.004
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:This cross-sectional study explored the prevalence of disordered eating attitudes, body shape concerns, and social anxiety and depressive symptoms in male and female medical students in China. METHOD:Four hundred eighty-seven students from Central South University (Hunan Province, Changsha City, China) compl...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2009.11.007
更新日期:2010-09-01 00:00:00
abstract:INTRODUCTION:Very few studies have explored the effect of exposure to disaster memorial reports in the media on long-term sleep quality during the recovery period and post-disaster era. This study investigated the relationship between exposure to memorial reports and adult survivors' long-term sleep quality 10 years af...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2019.152150
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:Recent studies have suggested that the brain circuitry mediating cue-induced desire for video games is similar to that elicited by cues related to drugs and alcohol. We hypothesized that desire for Internet video games during cue presentation would activate similar brain regions to those that have been linked...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2010.04.004
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Family history of suicidal behavior and suicide are both risk factors for suicide. However, the effects of family history of suicide versus suicide attempts on patient suicidal behavior remain unclear. The aim of the present study was to understand if family history of suicide as compared to family history o...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2016.06.006
更新日期:2016-10-01 00:00:00
abstract::Although several studies have addressed the issue of the relationship between the subjective response to neuroleptics and drug compliance, very little attention has been given to the study of the subjective experience of psychosis and drug attitudes. The present study was therefore undertaken to examine the relationsh...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1053/comp.2000.16566
更新日期:2000-11-01 00:00:00
abstract::The aim of the present study was to examine cognitive performance and basic symptoms (BS) in the relatives of schizophrenic patients. The experimental sample comprised 24 first-degree relatives of patients. Each relative was matched to one control. Cognitive tests were: Continuous Performance Test (CPT), N-Back Workin...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.comppsych.2008.01.001
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:Although it is well-established that juvenile offenders are at an elevated risk for depression and that, within this group, females have the highest risk, little is known regarding the trends in the prevalence of depression among juvenile offenders in the United States. In the present study, we systematically e...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2017.09.005
更新日期:2018-01-01 00:00:00
abstract::The goal of this study is to replicate an earlier epidemiological finding of seasonal changes in mood and behavior among Chinese medical students using an independent study population. Three hundred nineteen college students were surveyed with a Chinese version of the Seasonal Pattern Assessment Questionnaire (SPAQ) a...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(00)90132-9
更新日期:2000-01-01 00:00:00