Serum high molecular weight adiponectin is associated with mild renal dysfunction in Japanese adults.

abstract：AIM:The Japan EPA Lipid Intervention Study (JELIS) was the first prospective randomized clinical trial to demonstrate prevention of coronary events by pure eicosapentaenoic acid (EPA). The aim of this study was to examine the relationships between various plasma fatty acid concentrations and the risk of coronary events...

journal_title：Journal of atherosclerosis and thrombosis

authors： Itakura H,Yokoyama M,Matsuzaki M,Saito Y,Origasa H,Ishikawa Y,Oikawa S,Sasaki J,Hishida H,Kita T,Kitabatake A,Nakaya N,Sakata T,Shimada K,Shirato K,Matsuzawa Y,JELIS Investigators.

更新日期：2011-01-01 00:00:00

abstract：AIM:A new antibody reacted with an epitope in Lp(a) that has undergone oxidation treatment, but is not present in native Lp(a), was developed. Thus, we determined serum oxidized Lp(a) concentration in healthy volunteers, and coronary artery disease (CAD), diabetes mellitus (DM), and hypertensive patients. METHODS:We m...

journal_title：Journal of atherosclerosis and thrombosis

authors： Morishita R,Ishii J,Kusumi Y,Yamada S,Komai N,Ohishi M,Nomura M,Hishida H,Niihashi M,Mitsumata M

更新日期：2009-08-01 00:00:00

abstract：AIM:In addition to the risk of progression to end-stage renal disease (ESRD), chronic kidney disease (CKD) is also known to be associated with an elevated risk of cardiovascular disease (CVD). Statins may improve renal function in CKD patients. METHODS:The database of the LIVALO Effectiveness and Safety (LIVES) Study,...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kimura K,Shimano H,Yokote K,Urashima M,Teramoto T

更新日期：2010-06-30 00:00:00

abstract：AIM:Atrial fibrillation (AF) is characterized by the development of thromboembolic events and is more prevalent among end-stage renal disease patients than in the general population. Vascular access thrombosis (VAT) is a major morbidity in chronic hemodialysis (HD) patients; however, the association between AF and VAT ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Chou CY,Chen JY,Liu JH,Liu YL,Lin HH,Yang YF,Wang SM,Kuo HL,Huang CC

更新日期：2011-01-01 00:00:00

abstract：AIM:Evidence is lacking about whether urinary stones are associated with the subsequent risk of cardiovascular diseases. Herein, we investigated the association between history of urinary stones and the risk of coronary heart disease (CHD) and stroke among middle-aged Japanese. METHODS:This cohort study included 89,03...

journal_title：Journal of atherosclerosis and thrombosis

authors： Arafa A,Eshak ES,Iso H,Shirai K,Muraki I,Sawada N,Tsugane S,JPHC Study Group.

更新日期：2020-11-01 00:00:00

abstract：:Lecithin-cholesterol acyltransferase (LCAT) is an important enzyme involved in the esterification of cholesterol. Here, we report a novel point mutation in the LCAT gene of a 63-year-old female with characteristics of classic familial LCAT deficiency. The patient's clinical manifestations included corneal opacity, mil...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wang XL,Osuga J,Tazoe F,Okada K,Nagashima S,Takahashi M,Ohshiro T,Bayasgalan T,Yagyu H,Okada K,Ishibashi S

更新日期：2011-01-01 00:00:00

abstract：AIMS:The clinical implications of stiffness of the carotid artery (CA) have not been fully clarified in the prediction of coronary artery disease (CAD), although intima-media thickness (IMT) has been established as a surrogate marker. We examined the associations of stiffness parameter beta (ST) and IMT with concurrent...

journal_title：Journal of atherosclerosis and thrombosis

authors： Lee E,Emoto M,Teramura M,Tsuchikura S,Ueno H,Shinohara K,Morioka T,Mori K,Koyama H,Shoji T,Okuno Y,Inaba M,Nishizawa Y

更新日期：2009-03-01 00:00:00

abstract：AIM:Existing evidence suggests that endothelial lipase (EL) plays an important role in high-densitylipoprotein (HDL) metabolism. Because rabbits are a useful animal model for the study of human lipid metabolism and atherosclerosis, we characterized rabbit EL (rEL) expression and investigated its relationship with plasm...

journal_title：Journal of atherosclerosis and thrombosis

authors： Zhang J,Yu Y,Nakamura K,Koike T,Waqar AB,Zhang X,Liu E,Nishijima K,Kitajima S,Shiomi M,Qi Z,Yu J,Graham MJ,Crooke RM,Ishida T,Hirata K,Hurt-Camejo E,Chen YE,Fan J

更新日期：2012-01-01 00:00:00

abstract：AIM:A simple, non-invasive medical device, using bioelectrical impedance analysis (BIA) for the evaluation of visceral fat level (VFL) was developed recently. The aim of this study was to investigate the utility of VFL by BIA in the screening of metabolic syndrome (MetS). METHODS:VFL was measured by the BIA device in ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Unno M,Furusyo N,Mukae H,Koga T,Eiraku K,Hayashi J

更新日期：2012-01-01 00:00:00

abstract：AIM:Both vascular function and structure are independent predictors of cardiovascular events. The purpose of this study was to evaluate vascular function and structure of a leg artery in patients with peripheral artery disease (PAD). METHODS:We measured flow-mediated vasodilatation (FMD) and nitroglycerine-induced vas...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iwamoto A,Kajikawa M,Maruhashi T,Iwamoto Y,Oda N,Kishimoto S,Matsui S,Kihara Y,Chayama K,Goto C,Noma K,Aibara Y,Nakashima A,Higashi Y

更新日期：2016-11-01 00:00:00

abstract：AIM:Paraoxonase-1 (PON1) is an antioxidant enzyme located in high density lipoprotein (HDL). PON1 was defined as a protective factor against atherosclerosis. The aim of this study was to investigate the possible relationship between serum paraoxonase (PONase), homocysteine thiolactonase (HTase) activities and PON1 Q192...

journal_title：Journal of atherosclerosis and thrombosis

authors： Bayrak A,Bayrak T,Tokgözoglu SL,Volkan-Salanci B,Deniz A,Yavuz B,Alikasifoglu M,Demirpençe E

更新日期：2012-01-01 00:00:00

abstract：AIM:Heterozygous patients with familial hypercholesterolemia (FH) are known to be associated with a high risk of coronary artery disease (CAD), which is a major determinant of their clinical outcome. The prognosis of heterozygous FH patients substantially varies, being dependent on the level of their CAD risk, and thei...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sugisawa T,Okamura T,Makino H,Watanabe M,Kishimoto I,Miyamoto Y,Iwamoto N,Yamamoto A,Yokoyama S,Harada-Shiba M

更新日期：2012-01-01 00:00:00

abstract：AIM:Up-regulation of soluble CD40 ligand (sCD40L) and of monocyte chemoattractant protein-1 (MCP-1) has been found in diabetes and in patients with acute cerebral ischemia. We asked whether (i) the two molecules are similarly upregulated among non-lacunar and lacunar diabetic strokes and (ii) sCD40L and/or MCP-1 predic...

journal_title：Journal of atherosclerosis and thrombosis

authors： Davì G,Tuttolomondo A,Santilli F,Basili S,Ferrante E,Di Raimondo D,Pinto A,Licata G

更新日期：2009-01-01 00:00:00

abstract：AIM:Epicardial adipose tissue (EAT) is implicated in the development of coronary atherosclerosis.We sought to investigate the association between the EAT thickness and presence of multivessel disease (MV) in patients with acute myocardial infarction (AMI). METHODS:We enrolled 45 consecutive patients with AMI who under...

journal_title：Journal of atherosclerosis and thrombosis

authors： Fukamachi D,Higuchi Y,Hiro T,Takayama T,Kanai T,Sudo M,Nishida T,Iida K,Saito S,Hirayama A

更新日期：2015-01-01 00:00:00

abstract：AIM:The purpose of this study is to investigate the impact of arterial stiffness assessed using Cardio-ankle Vascular Index (CAVI) on long-term outcome after acute coronary syndrome (ACS). METHODS:A total of 387 consecutive patients (324 males; age, 64±11 years) with ACS were enrolled. We examined CAVI and brachial-an...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kirigaya J,Iwahashi N,Tahakashi H,Minamimoto Y,Gohbara M,Abe T,Akiyama E,Okada K,Matsuzawa Y,Maejima N,Hibi K,Kosuge M,Ebina T,Tamura K,Kimura K

更新日期：2020-07-01 00:00:00

abstract：AIM:Moderate alcohol consumption appears to confer some protection against coronary heart disease, which is related to an increase in high-density lipoprotein cholesterol (HDL-C). The genotype of aldehyde dehydrogenase 2 (ALDH2) is closely related to alcohol metabolism but a relationship between ALDH2 genotypes and HDL...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wada M,Daimon M,Emi M,Iijima H,Sato H,Koyano S,Tajima K,Kawanami T,Kurita K,Hunt SC,Hopkins PN,Kubota I,Kawata S,Kato T

更新日期：2008-08-01 00:00:00

abstract：AIM:The purpose of this study was to evaluate the efficacy and safety of LIVALO tablets (pitavastatin) in Japanese male children with heterozygous familial hypercholesterolemia (FH). METHODS:A multicenter, randomized, double-blind, parallel study was conducted in 14 male children 10-15 years of age with heterozygous F...

journal_title：Journal of atherosclerosis and thrombosis

authors： Harada-Shiba M,Arisaka O,Ohtake A,Okada T,Suganami H,NK-104-PH 01 study registration group.

更新日期：2016-01-01 00:00:00

abstract：AIM:The Framingham risk score (FRS) is one of the standard tools used to predict the incidence of coronary heart disease (CHD). No previous study has investigated its efficacy for a Japanese population cohort. The purpose of this study was to develop new coronary prediction algorithms for the Japanese population in the...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nishimura K,Okamura T,Watanabe M,Nakai M,Takegami M,Higashiyama A,Kokubo Y,Okayama A,Miyamoto Y

更新日期：2014-01-01 00:00:00

abstract：:Receptors belonging to the low density lipoprotein receptor (LDLR) superfamily play important biological roles in addition to mediating the lipoprotein metabolism. The recent discovery of a novel mosaic LDLR family member by us (Yamazaki H, Bujo H, Kusunoki J, Seimiya K, Kanaki T, Morisaki N, Schneider WJ, and Saito Y...

journal_title：Journal of atherosclerosis and thrombosis

authors： Bujo H,Saito Y

更新日期：2000-01-01 00:00:00

abstract：AIM:The arterial pressure-volume index (API) and arterial velocity-pulse index (AVI) are novel measurement indices of arterial stiffness. This study was performed to examine the screening validity of the API and AVI for preclinical atherosclerosis in Japanese community-dwelling adults. METHODS:We conducted a cross-sec...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yamanashi H,Koyamatsu J,Nagayoshi M,Shimizu Y,Kawashiri SY,Kondo H,Fukui S,Tamai M,Maeda T

更新日期：2018-09-01 00:00:00

abstract：AIM:Glucagon-like peptide-1 can reduce both postprandial plasma glucose (PG) and chylomicron (CM) levels in patients with type 2 diabetes. However, there have been no reports regarding the relationship between the postprandial metabolism of PG and CM. METHODS:Patients with type 2 diabetes who were admitted for glycemi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okajima F,Emoto N,Kato K,Sugihara H

更新日期：2017-02-01 00:00:00

abstract：AIM:Malnutrition has been identified to be an independent predictor of morbidity and mortality in patients with chronic heart failure (CHF). However, the pathophysiological mechanisms underlying this pathway remain unclear. METHODS:Nutritional screening was performed using the controlling nutritional status (CONUT) sc...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nakagomi A,Kohashi K,Morisawa T,Kosugi M,Endoh I,Kusama Y,Atarashi H,Shimizu W

更新日期：2016-06-01 00:00:00

abstract：AIM:To evaluate the effect of statin therapy on the decrease of common carotid artery intima-media thickness (CCA-IMT) compared to placebo or usual care. METHODS:A systematic search of electronic databases (MEDLINE, EMBASE, and Cochrane Center Register) up to December 2011 was performed. Two reviewers independently de...

journal_title：Journal of atherosclerosis and thrombosis

authors： Huang Y,Li W,Dong L,Li R,Wu Y

更新日期：2013-01-01 00:00:00

abstract：:Arterial stiffness is increased in type 2 diabetes mellitus, and diabetes preferentially affects arterial stiffness of the central (elastic, capacitive) over peripheral (muscular, conduit) arteries. We hypothesized that arterial stiffness of the central artery may be more closely associated with ischemic heart disease...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hatsuda S,Shoji T,Shinohara K,Kimoto E,Mori K,Fukumoto S,Koyama H,Emoto M,Nishizawa Y

更新日期：2006-04-01 00:00:00

abstract：:The constellation of metabolic abnormalities including centrally distributed obesity, decreased high-density lipoprotein cholesterol (HDL-C), elevated triglycerides, elevated blood pressure (BP), and hyperglycaemia is known as the metabolic syndrome. Associated with a 3 fold and 2 fold increase in type 2 diabetes and ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Zimmet P,Magliano D,Matsuzawa Y,Alberti G,Shaw J

更新日期：2005-01-01 00:00:00

abstract：:Elevated resting heart rate (HR) is associated with hypertension in addition to or similar to increased incidence of cardiovascular morbidity and mortality. Subjects with high HR exhibit the characteristic features of insulin resistance syndrome. Sympathetic overactivity underlies this clinical condition. However, the...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hasegawa T,Watase H

更新日期：2003-01-01 00:00:00

abstract：AIM:To examine the association between renal vasculature changes and generalized atherosclerosis using autopsy cases. METHODS:We histologically examined 107 autopsy patients(mean age, 68.4 years; 64% men; 81% non-CVD) to investigate the association between renal vasculature changes and generalized atherosclerosis. We ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iwakiri T,Sato Y,Matsuura Y,Hatakeyama K,Marutsuka K,Yamashita A,Fujimoto S,Kitamura K,Asada Y

更新日期：2014-01-01 00:00:00

abstract：AIM:The aim of the current study was to investigate circulating adiponectin levels and their associated factors in young lean healthy Japanese women. METHODS:We recruited 82 healthy Japanese women in their twenties and thirties with their body mass index <25 kg/m(2), and performed anthropometric, sphygmomanometric, an...

journal_title：Journal of atherosclerosis and thrombosis

authors： Takahara M,Katakami N,Kishida K,Kaneto H,Funahashi T,Shimomura I,Matsunaga S,Kubo S,Fukamizu H,Otsuka A,Ichihara K,Nakamura T

更新日期：2013-01-01 00:00:00

abstract：AIM:Homocysteine is associated with increased arterial resistance and eventually causes luminal reduction. The purpose of the present study was to evaluate an association between the plasma concentration of total homocysteine (tHcy) and stenosis or occlusion of the internal carotid artery (ICA) in patients with ischemi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Jeong SK,Seo JY,Cho YI

更新日期：2010-09-30 00:00:00

abstract：AIM:Angiotensin (Ang) II-induced abdominal aortic aneurysm (AAA) in apoE-deficient mice has been used as a model of human AAA, but it has been unclear why the progression of AAA continues after stopping the Ang II infusion. The involvement of vascular Ang II-forming enzymes in the progression of AAA was studied. METHO...

journal_title：Journal of atherosclerosis and thrombosis

authors： Inoue N,Muramatsu M,Jin D,Takai S,Hayashi T,Katayama H,Kitaura Y,Tamai H,Miyazaki M

更新日期：2009-06-01 00:00:00