Relationships between plasma fatty acid composition and coronary artery disease.

abstract：AIM:Because the prevalence of hyperuricemia is lower in females than in males, the association between hyperuricemia and cardiovascular disease has been frequently reported in females. Increased serum uric acid levels are associated with the presence of cardiovascular risk factors such as hypertension, renal dysfunctio...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ando K,Takahashi H,Watanabe T,Daidoji H,Otaki Y,Nishiyama S,Arimoto T,Shishido T,Miyashita T,Miyamoto T,Kubota I

更新日期：2016-08-01 00:00:00

abstract：:Measurement of arterial stiffness in routine medical practice is important to assess the progression of arteriosclerosis. So far, many parameters have been proposed to quantitatively represent arterial stiffness. Among these, pulse wave velocity (PWV) has been most frequently applied to clinical medicine because those...

journal_title：Journal of atherosclerosis and thrombosis

authors： Saiki A,Sato Y,Watanabe R,Watanabe Y,Imamura H,Yamaguchi T,Ban N,Kawana H,Nagumo A,Nagayama D,Ohira M,Endo K,Tatsuno I

更新日期：2016-01-01 00:00:00

abstract：:Recent findings suggest that the oxidative modification of low-density lipoproteins (LDL) and an increase in triglyceride-rich lipoprotein particles including chylomicron remnants contribute to the progression of atherosclerosis, as does the inflammatory response. We therefore examined whether and how these lipoprotei...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okumura T,Fujioka Y,Morimoto S,Masai M,Sakoda T,Tsujino T,Kashiwamura S,Okamura H,Ohyanagi M

更新日期：2006-02-01 00:00:00

abstract：:The plasma levels of blood coagulation and fibrinolytic factors and the serum levels of lipids were measured in 62 subjects (22 normolipidemia and 40 hyperlipidemia) to investigate whether hyperlipidemia may affect the hemostatic system. Prothrombin, factors VII, IX and X were elevated in hyperlipidemic patients. The ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Morishita E,Jokaji H,Matsuda T

更新日期：1995-01-01 00:00:00

abstract：AIM:To examine the impact of C-reactive protein on the risks of stroke and its subtypes, particularly among Asian populations in which median C-reactive protein levels are typically lower than in Western populations. METHODS:A prospective, nested case-control study was conducted to examine the associations between hig...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iso H,Noda H,Ikeda A,Yamagishi K,Inoue M,Iwasaki M,Tsugane S

更新日期：2012-01-01 00:00:00

abstract：AIM:Sarcopenic obesity (SO) is closely associated with cardiovascular disease (CVD) in elderly women. Increases in body fat and decreases in muscle mass are closely associated with increased carotid intima-media thickness (CIMT). The aim of this study was to examine the influence of a 24-week aerobic and resistance tra...

journal_title：Journal of atherosclerosis and thrombosis

authors： Park J,Kwon Y,Park H

更新日期：2017-11-01 00:00:00

abstract：AIMS:Considering that cerebral infarction (CI) may share a common etiological basis with coronary artery disease (CAD), we evaluated six CAD-related single-nucleotide polymorphisms (SNPs) on 9p21 for investigating the effect of 9p21 on CI or carotid plaque in the Chinese Han population. METHODS:Altogether, 528 patient...

journal_title：Journal of atherosclerosis and thrombosis

authors： Lu Z,Zhang Y,Maimaiti Y,Feng Y,Sun J,Zhuang J,Zeng L,Fu Y

更新日期：2015-01-01 00:00:00

abstract：AIM:There are few data regarding associations between sleep duration and subclinical atherosclerosis in Japan. The aim of this study was to evaluate associations of self-reported sleep duration with calcification in the coronary arteries (CAC) and carotid intima media thickness (IMT) in Japanese men. METHODS:This was ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Suzuki S,Arima H,Miyazaki S,Fujiyoshi A,Kadota A,Takashima N,Hisamatsu T,Kadowaki S,Zaid M,Torii S,Horie M,Murata K,Miura K,Ueshima H,SESSA Research Group.

更新日期：2018-02-01 00:00:00

abstract：AIM:The risk index for atherosclerotic cardiovascular diseases in the Japanese metabolic syndrome-focused health checkup program was changed from total cholesterol (TC) to low-density lipoprotein cholesterol (LDL-C). We discuss the validity of this change with respect to standardization. METHODS:The beta-quantificatio...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nakamura M,Koyama I,Iso H,Sato S,Okazaki M,Kayamori Y,Kiyama M,Kitamura A,Shimamoto T,Ishikawa Y

更新日期：2010-12-26 00:00:00

abstract：:Several reports have suggested that HDL has anti-oxidative actions. We investigated the relationship between HDL-cholesterol (HDL-C) and malondialdehyde-modified LDL (MDA-LDL) concentrations using enzyme linked immunosolvent assay. We divided our study subjects into four groups on the basis of concentrations of trigly...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kondo A,Li J,Manabe M,Saito K,Kanno T,Maekawa M

更新日期：2003-01-01 00:00:00

abstract：AIM:Adipose tissue inflammation induced by macrophage infiltration through the MCP-1/CCR2 pathway is considered to play a pivotal role in the development of visceral obesity and insulin resistance. In the present study, therefore, we examined whether pharmacological inhibition of CCR2 is effective against the developme...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tamura Y,Sugimoto M,Murayama T,Minami M,Nishikaze Y,Ariyasu H,Akamizu T,Kita T,Yokode M,Arai H

更新日期：2010-03-31 00:00:00

abstract：AIM:Carotid intima-media thickness (CIMT) measurements are used as a disease outcome in randomized controlled trials that assess the effects of lipid-modifying treatment. It is unclear whether common CIMT or mean maximum CIMT should be used as the primary outcome. We directly compared both measurements using aspects th...

journal_title：Journal of atherosclerosis and thrombosis

authors： Dogan S,Kastelein JJ,Grobbee DE,Bots ML

更新日期：2011-01-01 00:00:00

abstract：AIM:Glucagon-like peptide-1 can reduce both postprandial plasma glucose (PG) and chylomicron (CM) levels in patients with type 2 diabetes. However, there have been no reports regarding the relationship between the postprandial metabolism of PG and CM. METHODS:Patients with type 2 diabetes who were admitted for glycemi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okajima F,Emoto N,Kato K,Sugihara H

更新日期：2017-02-01 00:00:00

abstract：AIMS:Renal dysfunction is a major public health problem, but there have been few investigations of the relationship between serum high molecular weight (HMW) adiponectin and renal function in Japanese community-dwelling adults. METHODS:We randomly recruited a sample of 1,849 adult Japanese (793 men aged 60 ± 14 (mean ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kawamoto R,Tabara Y,Kohara K,Miki T,Abe M,Kusunoki T,Katoh T,Ohtsuka N

更新日期：2010-11-27 00:00:00

abstract：AIMS:Patients with chronic kidney disease (CKD) have a higher burden of cardiovascular morbidity and mortality than the general population. Endothelial dysfunction has been suggested to play a role in both glomerular filtration rate loss and cardiovascular damage. Thus, the present study aimed to evaluate the relations...

journal_title：Journal of atherosclerosis and thrombosis

authors： Li Y,Cui R,Liu K,Eshak ES,Cui M,Dong J,Imano H,Muraki I,Kiyama M,Kitamura A,Okada T,Yamagishi K,Umesawa M,Ohira T,Iso H,CIRCS investigators.

更新日期：2020-09-02 00:00:00

abstract：:A 77-year-old woman with type II diabetes mellitus was admitted to our hospital in August/ 1995 with severe hyperlipidemia. She had taken feedings through a nasogastric tube with 1000 ml (1000 kcal) of Ensureliquid daily since 1993 because of the muscle weakness after rhabdomyolysis. Her serum total cholesterol was 51...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tanaka S,Miki T,Hsieh ST,Kim JI,Yasumoto T,Taniguchi T,Ishikawa Y,Yokoyama M

更新日期：2003-01-01 00:00:00

abstract：:Sitosterolemia is a rare, autosomal recessive inherited sterol storage disease associated with high tissue and serum plant sterol concentrations, caused by mutations in the adenosine triphosphate-bind-ing cassette (ABC) transporter ABCG5 or ABCG8 genes. Markedly increased serum concentration of plant sterols. such as ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tsubakio-Yamamoto K,Nishida M,Nakagawa-Toyama Y,Masuda D,Ohama T,Yamashita S

更新日期：2010-09-30 00:00:00

abstract：AIM:The aim of this study was to assess the association between weight change and mortality due to cardiovascular diseases (CVDs) in a Japanese population. METHODS:We used the data of a population-based prospective cohort study that was conducted from 1988 to 1990 in 45 areas throughout Japan. Among a total of 69,681 ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okada C,Kubota Y,Eshak ES,Cui R,Tamakoshi A,Iso H,and the JACC Study Group.

更新日期：2021-01-01 00:00:00

abstract：:In atherosclerotic lesions, matrix metalloproteinases produced by foam cells (macrophages) are thought to increase plaque instability, promote plaque rupture, by degradating extracellular matrix. To investigate the relationship between the expression of these proteinases and the histologic appearance of atheromas, imm...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okamoto Y,Satomura K,Ohsuzu F,Nakamura H,Takeuchi K,Yoshioka M

更新日期：2001-01-01 00:00:00

abstract：AIM:We hypothesized that excessive suppression of platelet function due to antiplatelet therapy can increase the incidence of bleeding complications. The aim of the present study was to find whether we could predict bleeding events by measuring platelet function. METHODS:We enrolled 743 subjects whose platelet functio...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sairaku A,Nakano Y,Eno S,Hondo T,Matsuda K,Kisaka T,Kihara Y

更新日期：2011-01-01 00:00:00

abstract：AIM:High density lipoprotein (HDL) and its apolipoproteins can promote cholesterol efflux from macrophage foam cells via the ATP-binding cassette transporter A1 (ABCA1), ABCG1, and scavenger receptor class B type I (SR-BI). Liver X receptors (LXRs) operate as cholesterol sensors which may protect from cholesterol overl...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hu YW,Wang Q,Ma X,Li XX,Liu XH,Xiao J,Liao DF,Xiang J,Tang CK

更新日期：2010-05-01 00:00:00

abstract：AIM:We evaluated the impact of adherence to preferable behavior on serum lipid control assessed by a self-reported questionnaire in high-risk patients taking pravastatin for primary prevention of coronary artery disease. METHODS:High-risk patients taking pravastatin were followed for 2 years. Questionnaire surveys com...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kitagawa Y,Teramoto T,Daida H,APPROACH-J Study group.

更新日期：2012-01-01 00:00:00

abstract：AIM:Smoking induces vascular inflammation and increases the risk of cardiovascular events. Lectinlike oxidized low-density lipoprotein receptor-1 (LOX-1) is a scavenger receptor that is induced by oxidative stress and is associated with atherosclerotic plaque formation and destabilization. LOX-1 interacts with C-reacti...

journal_title：Journal of atherosclerosis and thrombosis

authors： Takanabe-Mori R,Ono K,Wada H,Takaya T,Ura S,Yamakage H,Satoh-Asahara N,Shimatsu A,Takahashi Y,Fujita M,Fujita Y,Sawamura T,Hasegawa K

更新日期：2013-01-01 00:00:00

abstract：AIM:The aim of this study was to investigate the clinical effect of planned endovascular therapy (EVT) for critical limb ischemia (CLI) patients with tissue loss. Although several rounds of EVT for CLI patients are required for complete wound healing, time required for complete wound healing depends on the wound severi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Fukunaga M,Kawasaki D,Nishimura M,Yamagami M,Fujiwara R,Nakata T

更新日期：2019-03-01 00:00:00

abstract：:The constellation of metabolic abnormalities including centrally distributed obesity, decreased high-density lipoprotein cholesterol (HDL-C), elevated triglycerides, elevated blood pressure (BP), and hyperglycaemia is known as the metabolic syndrome. Associated with a 3 fold and 2 fold increase in type 2 diabetes and ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Zimmet P,Magliano D,Matsuzawa Y,Alberti G,Shaw J

更新日期：2005-01-01 00:00:00

abstract：AIM:Inherent mechanisms leading to vascular smooth muscle cells (VSMC) alterations in obesitylinked type 2 diabetes (T2D) situation remain to be clarified. This study evaluates the impact of supernatant of adipocytes extracted from mice fed high-fat-diets (HFD) on the proliferation and apoptosis of VSMC. METHODS:Adipo...

journal_title：Journal of atherosclerosis and thrombosis

authors： El Akoum S,Cloutier I,Tanguay JF

更新日期：2012-01-01 00:00:00

abstract：AIM:The INK4b-ARF-INK4a locus in the chromosome 9p21 region is known to play an important role in the development of atherosclerosis. The INK4/ARF transcript p16(INK4a) inhibits the activity of the cyclin-dependent kinases CDK4/CDK6 and arrests cell-cycle progression. CDK inhibitors also regulate G1/S phase progression...

journal_title：Journal of atherosclerosis and thrombosis

authors： Bayoglu B,Arslan C,Gode S,Kaya Dagistanli F,Arapi B,Burc Deser S,Dirican A,Cengiz M

更新日期：2014-01-01 00:00:00

abstract：:Dysregulation of adipose tissue-derived bioactive molecules, termed adipokines, is recognized as common ground for insulin resistance and metabolic syndrome associated with obesity. However, adipokine dysregulation is paradoxically associated with lipodystrophy and lipoatrophy with aging. In familial partial lipodystr...

journal_title：Journal of atherosclerosis and thrombosis

authors： Arai Y,Takayama M,Abe Y,Hirose N

更新日期：2011-01-01 00:00:00

abstract：AIM:Obesity and metabolic syndrome (MetS) frequently coexist and are both important risk factors for cardiovascular disease. However, the pathophysiological role of obesity without MetS, also referred to as metabolically healthy obesity (MHO), remains unclear. In this study, we aim to clarify the effect of MHO on the d...

journal_title：Journal of atherosclerosis and thrombosis

authors： Itoh H,Kaneko H,Kiriyama H,Yoshida Y,Nakanishi K,Mizuno Y,Daimon M,Morita H,Yatomi Y,Yamamichi N,Komuro I

更新日期：2020-02-01 00:00:00

abstract：AIM:Hypercholesterolemic patients with inflammation are at high risk for cardiovascular events. Statins exert anti-inflammatory action independent of their cholesterol-lowering action. This study sought to clarify whether statin therapy reduces inflammatory markers in hypercholesterolemic patients and to determine fact...

journal_title：Journal of atherosclerosis and thrombosis

authors： Horiuchi Y,Hirayama S,Soda S,Seino U,Kon M,Ueno T,Idei M,Hanyu O,Tsuda T,Ohmura H,Miida T

更新日期：2010-07-30 00:00:00