Vascular Function and Intima-media Thickness of a Leg Artery in Peripheral Artery Disease: A Comparison of Buerger Disease and Atherosclerotic Peripheral Artery Disease.

abstract：AIM:High density lipoprotein (HDL) and its apolipoproteins can promote cholesterol efflux from macrophage foam cells via the ATP-binding cassette transporter A1 (ABCA1), ABCG1, and scavenger receptor class B type I (SR-BI). Liver X receptors (LXRs) operate as cholesterol sensors which may protect from cholesterol overl...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hu YW,Wang Q,Ma X,Li XX,Liu XH,Xiao J,Liao DF,Xiang J,Tang CK

更新日期：2010-05-01 00:00:00

abstract：:Vascular calcification is a common feature of advanced atherosclerosis resulting in reduced elasticity of elastic arteries. However, the relationship between elastic fibers and vascular calcification at the molecular and cellular levels remains unknown. We investigated the expression of major elastic fiber components ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sugitani H,Wachi H,Mecham RP,Seyama Y

更新日期：2002-01-01 00:00:00

abstract：AIM:There are few data regarding associations between sleep duration and subclinical atherosclerosis in Japan. The aim of this study was to evaluate associations of self-reported sleep duration with calcification in the coronary arteries (CAC) and carotid intima media thickness (IMT) in Japanese men. METHODS:This was ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Suzuki S,Arima H,Miyazaki S,Fujiyoshi A,Kadota A,Takashima N,Hisamatsu T,Kadowaki S,Zaid M,Torii S,Horie M,Murata K,Miura K,Ueshima H,SESSA Research Group.

更新日期：2018-02-01 00:00:00

abstract：AIM:Factor VII activating protease (FSAP) is a plasma serine protease involved in hemostasis and remodeling processes. Increased levels of circulating FSAP during pregnancy and in women using oral contraceptives (OCs) indicate that the hormonal status critically influences FSAP expression. In this respect, the aim of t...

journal_title：Journal of atherosclerosis and thrombosis

authors： Parahuleva MS,Langanke E,Hölschermann H,Parviz B,Abdallah Y,Stracke S,Tillmanns H,Kanse SM

更新日期：2012-01-01 00:00:00

abstract：:Bilirubin is a fundamental metabolic end product of heme degradation. Despite acting as a cytotoxic metabolite at high concentrations, bilirubin at physiological concentrations has antioxidant effects, such as scavenging reactive oxygen species, leading to a decrease in oxidative stress. Endothelial dysfunction is an ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Maruhashi T,Kihara Y,Higashi Y

更新日期：2019-08-01 00:00:00

abstract：AIM:Inter-arm blood pressure difference (IAD) is known to be associated with a composite of cardiovascular disease (CVD) and with CVD risk factors. However, only limited information is available regarding the contribution of diabetes mellitus to IAD and the association of IAD with individual CVDs, such as coronary arte...

journal_title：Journal of atherosclerosis and thrombosis

authors： Miyashima M,Shoji T,Kakutani Y,Yamazaki Y,Ochi A,Morioka T,Shinohara-Mitsuki K,Fukumoto S,Shioi A,Inaba M,Emoto M

更新日期：2020-08-01 00:00:00

abstract：AIM:To investigatethe association of plasma epoxyeicosatrienoic acids (EETs) with early neurologic deterioration (END), and whether EETs are mediated by EPHX2 variants in patients with minor ischemic stroke (MIS). METHOD:This was a prospective, multi-center observational study in patients with acute MIS in the Chinese...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yi X,Lin J,Li J,Zhou Q,Han Z

更新日期：2017-12-01 00:00:00

abstract：AIM:Recent evidence suggests that small dense low-density lipoprotein (sd-LDL) particles are more atherogenic than large-LDL in spite of their lower cholesterol content. This study aimed to determine whether sd-LDL-cholesterol (sd-LDL-C) is superior to LDL-C as a biomarker of coronary heart disease (CHD). METHODS:LDL ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Koba S,Yokota Y,Hirano T,Ito Y,Ban Y,Tsunoda F,Sato T,Shoji M,Suzuki H,Geshi E,Kobayashi Y,Katagiri T

更新日期：2008-10-01 00:00:00

abstract：AIM:Macrophage migration inhibitory factor (MIF) is known as a pro-inflammatory cytokine that regulates a broad spectrum of inflammatory reactions. MIF is expressed in vascular smooth muscle cells (VSMCs), and inhibition of the progression of atherosclerosis was observed in MIF-deficient atherosclerotic mice. However, ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okamoto T,Atsumi T,Shimizu C,Yoshioka N,Koike T

更新日期：2008-02-01 00:00:00

abstract：AIM:We investigated the effects of a calorie-restricted low-carbohydrate diet on glucose and lipid metabolism, and body fat distribution, especially on the secretion of leptin and lipoprotein lipase from adipose tissue in Otsuka Long Evans Tokushima Fatty (OLETF) rats. METHODS:Forty-three week-old male OLETF rats were...

journal_title：Journal of atherosclerosis and thrombosis

authors： Koide N,Oyama T,Miyashita Y,Shirai K

更新日期：2007-10-01 00:00:00

abstract：:Sitosterolemia is a rare, autosomal recessive inherited sterol storage disease associated with high tissue and serum plant sterol concentrations, caused by mutations in the adenosine triphosphate-bind-ing cassette (ABC) transporter ABCG5 or ABCG8 genes. Markedly increased serum concentration of plant sterols. such as ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tsubakio-Yamamoto K,Nishida M,Nakagawa-Toyama Y,Masuda D,Ohama T,Yamashita S

更新日期：2010-09-30 00:00:00

abstract：:To determine the recent serum lipid levels and other serum variables in the general Japanese population and trends in their changes over the past 40 years, a nationwide survey of serum lipid levels was conducted in 36 institutes from various districts around Japan in 2000. The total number of subjects was 12,839, aged...

journal_title：Journal of atherosclerosis and thrombosis

authors： Arai H,Yamamoto A,Matsuzawa Y,Saito Y,Yamada N,Oikawa S,Mabuchi H,Teramoto T,Sasaki J,Nakaya N,Itakura H,Ishikawa Y,Ouchi Y,Horibe H,Kita T

更新日期：2005-01-01 00:00:00

abstract：AIM:The prognostic value of homocysteine (HCY) in patients with coronary artery diseases (CAD) is still controversial. The objective of this study was to investigate whether elevated HCY level at admission predict long-term outcomes in patients after percutaneous coronary interventions (PCI) with coronary artery stenti...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yeh JK,Chen CC,Hsieh MJ,Tsai ML,Yang CH,Chen DY,Chang SH,Wang CY,Lee CH,Hsieh IC

更新日期：2017-07-01 00:00:00

abstract：AIM:The purpose of this study is to investigate the impact of arterial stiffness assessed using Cardio-ankle Vascular Index (CAVI) on long-term outcome after acute coronary syndrome (ACS). METHODS:A total of 387 consecutive patients (324 males; age, 64±11 years) with ACS were enrolled. We examined CAVI and brachial-an...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kirigaya J,Iwahashi N,Tahakashi H,Minamimoto Y,Gohbara M,Abe T,Akiyama E,Okada K,Matsuzawa Y,Maejima N,Hibi K,Kosuge M,Ebina T,Tamura K,Kimura K

更新日期：2020-07-01 00:00:00

abstract：AIM:Existing evidence suggests that endothelial lipase (EL) plays an important role in high-densitylipoprotein (HDL) metabolism. Because rabbits are a useful animal model for the study of human lipid metabolism and atherosclerosis, we characterized rabbit EL (rEL) expression and investigated its relationship with plasm...

journal_title：Journal of atherosclerosis and thrombosis

authors： Zhang J,Yu Y,Nakamura K,Koike T,Waqar AB,Zhang X,Liu E,Nishijima K,Kitajima S,Shiomi M,Qi Z,Yu J,Graham MJ,Crooke RM,Ishida T,Hirata K,Hurt-Camejo E,Chen YE,Fan J

更新日期：2012-01-01 00:00:00

abstract：AIM:Associations between long-term exposure to particulate matter (PM) and increased cardiovascular mortality have been reported, but few studies have investigated the associated incidence of cardiovascular disease, and none involved men. METHODS:We used data on 78,057 participants (37,121 men, 40,936 women) to examin...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nishiwaki Y,Michikawa T,Takebayashi T,Nitta H,Iso H,Inoue M,Tsugane S,Japan Public Health Center-based Prospective Study Group.

更新日期：2013-01-01 00:00:00

abstract：:Macrophage or macrophage-derived foam cell death is one of the characteristic events in the development of cell-poor lipid-rich cores of the advanced atherosclerotic plaques. Although the in vivo mechanism for the death of macrophages is unclear, one possible candidate for the agent which induces macrophage cell death...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hakamata H,Miyazaki A,Sakai M,Sakamoto YI,Horiuchi S

更新日期：1998-01-01 00:00:00

abstract：AIM:We evaluated the impact of adherence to preferable behavior on serum lipid control assessed by a self-reported questionnaire in high-risk patients taking pravastatin for primary prevention of coronary artery disease. METHODS:High-risk patients taking pravastatin were followed for 2 years. Questionnaire surveys com...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kitagawa Y,Teramoto T,Daida H,APPROACH-J Study group.

更新日期：2012-01-01 00:00:00

abstract：AIM:Smoking induces vascular inflammation and increases the risk of cardiovascular events. Lectinlike oxidized low-density lipoprotein receptor-1 (LOX-1) is a scavenger receptor that is induced by oxidative stress and is associated with atherosclerotic plaque formation and destabilization. LOX-1 interacts with C-reacti...

journal_title：Journal of atherosclerosis and thrombosis

authors： Takanabe-Mori R,Ono K,Wada H,Takaya T,Ura S,Yamakage H,Satoh-Asahara N,Shimatsu A,Takahashi Y,Fujita M,Fujita Y,Sawamura T,Hasegawa K

更新日期：2013-01-01 00:00:00

abstract：:We investigated in vitro effect of simvastatin, a potent 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on the proliferation of human and bovine endothelial cells (EC) compared to that of bovine smooth muscle cells (SMC). Cells were cultured in a medium supplemented with 10% normal serum (FBS). S...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sato I,Ma L,Ikeda M,Morita I,Murota S

更新日期：1998-01-01 00:00:00

abstract：AIM:Patients with acute infectious diseases are at an increased risk of venous thromboembolism (VTE). Clinicians should be aware of the VTE risk in patients with COVID-19, many of whom present with severe coagulation disorders. METHOD:We used an online platform to conduct a cross-sectional questionnaire survey among d...

journal_title：Journal of atherosclerosis and thrombosis

authors： Zhang Z,Xi L,Zhang S,Zhang Y,Pang W,Wang Y,Li C,Zhai Z,Wang C

更新日期：2020-10-01 00:00:00

abstract：AIM:To evaluate whether plaque scoring measurements are able to track changes in atherosclerotic plaque burden over time and to study whether this is affected by lipid-lowering therapy. METHODS:Data used were from METEOR (Measuring Effects on Intima-Media Thickness: an Evaluation Of Rosuvastatin), a randomized control...

journal_title：Journal of atherosclerosis and thrombosis

authors： Peters SA,Dogan S,Meijer R,Palmer MK,Grobbee DE,Crouse JR 3rd,O'Leary DH,Evans GW,Raichlen JS,Bots ML

更新日期：2011-01-01 00:00:00

abstract：AIM:In animals, dietary energy restriction is reported to increase longevity, whereas in humans, all cohort studies from Western countries have not shown an association between the low energy intake and longevity. We examined the association between total energy intake and longevity in Japan where dietary pattern is di...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nagai M,Ohkubo T,Miura K,Fujiyoshi A,Okuda N,Hayakawa T,Yoshita K,Arai Y,Nakagawa H,Nakamura K,Miyagawa N,Takashima N,Kadota A,Murakami Y,Nakamura Y,Abbott RD,Okamura T,Okayama A,Ueshima H,NIPPON DATA80 Research Gro

更新日期：2016-01-01 00:00:00

abstract：:The effects of combination therapy of angiotensin II receptor blockers (ARBs) and a calcium antagonist, benidipine hydrochloride, on glucose and lipid metabolism and pulse pressure were studied in elderly hypertensive patients with type 2 diabetes mellitus. Twenty-five hypertensive diabetic patients aged 65 years or o...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sasaki H,Kanai S,Oyama T,Miyashita Y,Yamamura S,Shirai K

更新日期：2006-06-01 00:00:00

abstract：AIM:To properly assess the guidance for perioperative management, we undertook a clinical epidemiology study with the primary aim of evaluating the incidence of perioperative vascular complications and their associated factors in a cohort of Japanese patients who underwent non-cardiac surgery in a tertiary medical care...

journal_title：Journal of atherosclerosis and thrombosis

authors： Aoyama-Mani C,Kawachi S,Ogawa Y,Kato N

更新日期：2014-01-01 00:00:00

abstract：AIM:Cardiovascular events associated with hypertension often involve thrombosis. Increased platelet activity is one of the risk factors of cardiovascular diseases. Antithrombotic properties of antihypertensive agents are not fully characterized. Angiotensin II type 1 receptor blockers (ARBs) are widely used for the tre...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sato Y,Fujii S,Imagawa S,Ohmura K,Ohmura Y,Andoh Y,Dong J,Ishimori N,Furumoto T,Tsutsui H

更新日期：2007-02-01 00:00:00

abstract：:Patients with chronic kidney disease (CKD) are at an increased risk not only for end-stage kidney disease (ESKD) but also for cardiovascular disease (CVD). In this review article, we summarize the current evidence of CKD as a high-risk condition for CVD based on reports from Japan and other countries to draw attention...

journal_title：Journal of atherosclerosis and thrombosis

authors： Shoji T,Abe T,Matsuo H,Egusa G,Yamasaki Y,Kashihara N,Shirai K,Kashiwagi A,Committee of Renal and Peripheral Arteries, Japan Atherosclerosis Society.

更新日期：2012-01-01 00:00:00

abstract：:The signaling and functions of the Endothelial Differentiation Gene (EDG) family of G protein-coupled receptors have been extensively elucidated. All the members of EDG family were shown to be receptors for lysosphingolipids or lysophospholipids. EDG-1, the prototype of EDG family receptors, is a high affinity recepto...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ozaki H,Hla T,Lee MJ

更新日期：2003-01-01 00:00:00

abstract：AIM:Increased levels of small dense low-density lipoproteins (sd-LDL) have been reported more atherogenic compared to total low-density lipoprotein (LDL); however, no definitive experiments using macrophages have examined this concept in vitro. METHOD AND RESULT:In this study, we isolated fractions of total LDL (densi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tani M,Kawakami A,Mizuno Y,Imase R,Ito Y,Kondo K,Ishii H,Yoshida M

更新日期：2011-01-01 00:00:00

abstract：AIM:Atherosclerosis (AS) characterized as a chronic inflammatory disease. Multiple immune cells and inflammatory cytokines, such as high mobility group protein (HMGB1), regulatory T (Treg) cells, T helper (Th17) cells, and inflammation-related cytokines, play a key role in its pathophysiology. A large number of studies...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ding JW,Zheng XX,Zhou T,Tong XH,Luo CY,Wang XA

更新日期：2016-06-01 00:00:00