The combination of IMT and stiffness parameter beta is highly associated with concurrent coronary artery disease in type 2 diabetes.

abstract：AIM:Factor VII activating protease (FSAP) is a plasma serine protease involved in hemostasis and remodeling processes. Increased levels of circulating FSAP during pregnancy and in women using oral contraceptives (OCs) indicate that the hormonal status critically influences FSAP expression. In this respect, the aim of t...

journal_title：Journal of atherosclerosis and thrombosis

authors： Parahuleva MS,Langanke E,Hölschermann H,Parviz B,Abdallah Y,Stracke S,Tillmanns H,Kanse SM

更新日期：2012-01-01 00:00:00

abstract：AIM:High density lipoprotein (HDL) and its apolipoproteins can promote cholesterol efflux from macrophage foam cells via the ATP-binding cassette transporter A1 (ABCA1), ABCG1, and scavenger receptor class B type I (SR-BI). Liver X receptors (LXRs) operate as cholesterol sensors which may protect from cholesterol overl...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hu YW,Wang Q,Ma X,Li XX,Liu XH,Xiao J,Liao DF,Xiang J,Tang CK

更新日期：2010-05-01 00:00:00

abstract：AIM:The prospective, randomized, multicenter Myocardial Ischemia Treated with Percutaneous Coronary Intervention and Plaque Regression by Lipid Lowering & Blood Pressure Controlling assessed by Intravascular Ultrasonography (MILLION) study demonstrated that combined treatment with atorvastatin and amlodipine enhanced c...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sakata K,Gamou T,Tada H,Hayashi K,Ino H,Yamagishi M,Masa-aki Kawashiri.,behalf of the MILLION Study Group.

更新日期：2019-05-01 00:00:00

abstract：:Although many clinical studies have shown that a low testosterone level is associated with cardiovascular diseases, the role of androgens in cardiovascular physiology and pathophysiology remains controversial. Androgens exert various actions in their target organs, and the androgen receptor (AR) is widely distributed ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yoshida S,Ikeda Y,Aihara K

更新日期：2016-01-01 00:00:00

abstract：:Statins are the main treatment for hypercholesterolemia and the cornerstone of atherosclerotic cardiovascular disease prevention. Many patients taking statins report muscle-related symptoms, one of the most important causes of statin treatment discontinuation, which is associated with an increased risk of cardiovascul...

journal_title：Journal of atherosclerosis and thrombosis

authors： Alonso R,Cuevas A,Cafferata A

更新日期：2019-03-01 00:00:00

abstract：:A number of effective drugs have been developed through animal experiments, contributing to the health of many patients. In particular, the WHHL rabbit family (WHHL rabbits and its advanced strains (coronary atherosclerosis-prone WHHL-CA rabbits and myocardial infarction-prone WHHLMI rabbits) developed at Kobe Univers...

journal_title：Journal of atherosclerosis and thrombosis

authors： Shiomi M

更新日期：2020-02-01 00:00:00

abstract：AIM:Inter-arm blood pressure difference (IAD) is known to be associated with a composite of cardiovascular disease (CVD) and with CVD risk factors. However, only limited information is available regarding the contribution of diabetes mellitus to IAD and the association of IAD with individual CVDs, such as coronary arte...

journal_title：Journal of atherosclerosis and thrombosis

authors： Miyashima M,Shoji T,Kakutani Y,Yamazaki Y,Ochi A,Morioka T,Shinohara-Mitsuki K,Fukumoto S,Shioi A,Inaba M,Emoto M

更新日期：2020-08-01 00:00:00

abstract：:Macrophage or macrophage-derived foam cell death is one of the characteristic events in the development of cell-poor lipid-rich cores of the advanced atherosclerotic plaques. Although the in vivo mechanism for the death of macrophages is unclear, one possible candidate for the agent which induces macrophage cell death...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hakamata H,Miyazaki A,Sakai M,Sakamoto YI,Horiuchi S

更新日期：1998-01-01 00:00:00

abstract：AIMS:Recently, a number of studies have shown an increased red blood cell distribution width (RDW) to be a strong and independent predictor of the prognosis of coronary artery disease. The aim of this study was to investigate the underlying mechanisms responsible for the relationship between the RDW and a poor prognosi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wang P,Wang Y,Li H,Wu Y,Chen H

更新日期：2015-01-01 00:00:00

abstract：:To determine the recent serum lipid levels and other serum variables in the general Japanese population and trends in their changes over the past 40 years, a nationwide survey of serum lipid levels was conducted in 36 institutes from various districts around Japan in 2000. The total number of subjects was 12,839, aged...

journal_title：Journal of atherosclerosis and thrombosis

authors： Arai H,Yamamoto A,Matsuzawa Y,Saito Y,Yamada N,Oikawa S,Mabuchi H,Teramoto T,Sasaki J,Nakaya N,Itakura H,Ishikawa Y,Ouchi Y,Horibe H,Kita T

更新日期：2005-01-01 00:00:00

abstract：AIM:Epicardial adipose tissue (EAT) may be associated with arrhythmogenesis. P-wave indices such as P-wave dispersion and P-wave variation indicated a slowed conduction velocity within the atria. This study investigated the effect of dapagliflozin on EAT volume and P-wave indices. METHODS:In the present ad hoc analysi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sato T,Aizawa Y,Yuasa S,Fujita S,Ikeda Y,Okabe M

更新日期：2020-12-01 00:00:00

abstract：AIM:It remains uncertain whether chronic exposure to particulate air pollution is associated with increased mortality in Japan because Japan has a different distribution pattern of cardiovascular disease and its risk factors compared to Western countries. We investigated the association between long-term exposure to pa...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ueda K,Nagasawa SY,Nitta H,Miura K,Ueshima H,NIPPON DATA80 Research Group.

更新日期：2012-01-01 00:00:00

abstract：AIM:Cardio-ankle vascular index (CAVI) reflects arterial stiffness and has been established as a useful surrogate marker of atherosclerosis. Contrary to the abundant data indicating slower progression of atherosclerosis with statins, studies on fibrates remain scarce. The aim of this study was thus to clarify the effec...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yamaguchi T,Shirai K,Nagayama D,Nakamura S,Oka R,Tanaka S,Watanabe Y,Imamura H,Sato Y,Kawana H,Ohira M,Saiki A,Shimizu N,Tatsuno I

更新日期：2019-07-01 00:00:00

abstract：AIM:Withholding effective treatment is clinically prevalent. The CEntralized Pan-Asian survey on tHE Under-treatment of hypercholeSterolemia (CEPHEUS-PA) indicated suboptimal low-density lipoprotein cholesterol (LDL-C) goal attainment in Taiwan, which may be attributable to clinical inertia. We herein analyzed the Taiw...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wang KL,Wu CH,Wang KF,Chang CC,Chen LC,Lu TM,Lin SJ,Chiang CE

更新日期：2014-01-01 00:00:00

abstract：AIM:Inflammation plays a critical role in the development of atherosclerotic plaque, and lipopolysaccharide (LPS) is a potentially important source of inflammation. The aim of this study was to develop a rabbit model of spontaneous thrombosis mimicking the pathophysiological and morphological characteristics of atheros...

journal_title：Journal of atherosclerosis and thrombosis

authors： Liu H,Hou J,Hu S,Du X,Fang Y,Jia H,Feng L,Zhang L,Du J,Zhao Q,Xie Z,Yu B

更新日期：2014-01-01 00:00:00

abstract：AIM:To evaluate whether plaque scoring measurements are able to track changes in atherosclerotic plaque burden over time and to study whether this is affected by lipid-lowering therapy. METHODS:Data used were from METEOR (Measuring Effects on Intima-Media Thickness: an Evaluation Of Rosuvastatin), a randomized control...

journal_title：Journal of atherosclerosis and thrombosis

authors： Peters SA,Dogan S,Meijer R,Palmer MK,Grobbee DE,Crouse JR 3rd,O'Leary DH,Evans GW,Raichlen JS,Bots ML

更新日期：2011-01-01 00:00:00

abstract：AIM:Atrial fibrillation (AF) is characterized by the development of thromboembolic events and is more prevalent among end-stage renal disease patients than in the general population. Vascular access thrombosis (VAT) is a major morbidity in chronic hemodialysis (HD) patients; however, the association between AF and VAT ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Chou CY,Chen JY,Liu JH,Liu YL,Lin HH,Yang YF,Wang SM,Kuo HL,Huang CC

更新日期：2011-01-01 00:00:00

abstract：AIM:Lipoprotein lipase protein exists in preheparin serum (preheparin LpL mass), even though lipoprotein lipase activity is rarely detected. Recent clinical studies have clarified that low preheparin LpL mass concentration is an important coronary risk factor. The aim of this study was to clarify the effect of telmisar...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hitsumoto T,Takahashi M,Iizuka T,Shirai K

更新日期：2008-06-01 00:00:00

abstract：:Coronary artery calcification (CAC) is a well-established surrogate marker of the total burden of coronary atherosclerosis. The CAC score, as measured on coronary computed tomography (CT), is associated with the prevalence of coronary artery disease (CAD) as well as cardiovascular morbidity and mortality. The CAC scor...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yamamoto H,Kitagawa T,Kihara Y

更新日期：2014-01-01 00:00:00

abstract：AIM:A positive association between metabolic syndrome (MetS) and periodontal status has recently been noted. However, no study has evaluated the relationship by sex and in a general urban population using the uniform definition proposed in the 2009 Joint Interim Statement. The aim of this study was to clarify the relat...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kikui M,Kokubo Y,Ono T,Kida M,Kosaka T,Yamamoto M,Watanabe M,Maeda Y,Miyamoto Y

更新日期：2017-05-01 00:00:00

abstract：AIMS:Adiponectin, an adipocyte-specific secretory protein, abundantly exists in the blood stream while its concentration paradoxically decreases in obesity. Hypoadiponectinemia is one of risks of cardiovascular diseases. However, impact of serum adiponectin concentration on acute ischemic myocardial damages has not bee...

journal_title：Journal of atherosclerosis and thrombosis

authors： Natsukawa T,Maeda N,Fukuda S,Yamaoka M,Fujishima Y,Nagao H,Sato F,Nishizawa H,Sawano H,Hayashi Y,Funahashi T,Kai T,Shimomura I

更新日期：2017-08-01 00:00:00

abstract：AIMS:Small arteries can be visualized in the ocular fundus, and findings of retinopathy based on Scheie classification are often applied to evaluate the impact of hypertension and atherosclerosis. However, the relationship between damage in the large and small arteries has not been investigated sufficiently, especially...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sugiura T,Dohi Y,Takagi Y,Yokochi T,Yoshikane N,Suzuki K,Tomiishi T,Nagami T,Iwase M,Takase H,Seo Y,Ohte N

更新日期：2020-11-25 00:00:00

abstract：:Measurement of arterial stiffness in routine medical practice is important to assess the progression of arteriosclerosis. So far, many parameters have been proposed to quantitatively represent arterial stiffness. Among these, pulse wave velocity (PWV) has been most frequently applied to clinical medicine because those...

journal_title：Journal of atherosclerosis and thrombosis

authors： Saiki A,Sato Y,Watanabe R,Watanabe Y,Imamura H,Yamaguchi T,Ban N,Kawana H,Nagumo A,Nagayama D,Ohira M,Endo K,Tatsuno I

更新日期：2016-01-01 00:00:00

abstract：AIM:Epicardial adipose tissue (EAT) is implicated in the development of coronary atherosclerosis.We sought to investigate the association between the EAT thickness and presence of multivessel disease (MV) in patients with acute myocardial infarction (AMI). METHODS:We enrolled 45 consecutive patients with AMI who under...

journal_title：Journal of atherosclerosis and thrombosis

authors： Fukamachi D,Higuchi Y,Hiro T,Takayama T,Kanai T,Sudo M,Nishida T,Iida K,Saito S,Hirayama A

更新日期：2015-01-01 00:00:00

abstract：AIM:This study tested the hypothesis that tacrolimus therapy limited left ventricular (LV) infarct and remodeling by suppressing the inflammatory response, oxidative stress and regulating the mitogen-activated protein kinase (MAPK) and Akt signaling pathways in an acute myocardial infarction (AMI) mini-pig model by lig...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yang CH,Sheu JJ,Tsai TH,Chua S,Chang LT,Chang HW,Lee FY,Chen YL,Chung SY,Sun CK,Leu S,Yen CH,Yip HK

更新日期：2013-01-01 00:00:00

abstract：AIM:The Japan EPA Lipid Intervention Study (JELIS) was the first prospective randomized clinical trial to demonstrate prevention of coronary events by pure eicosapentaenoic acid (EPA). The aim of this study was to examine the relationships between various plasma fatty acid concentrations and the risk of coronary events...

journal_title：Journal of atherosclerosis and thrombosis

authors： Itakura H,Yokoyama M,Matsuzaki M,Saito Y,Origasa H,Ishikawa Y,Oikawa S,Sasaki J,Hishida H,Kita T,Kitabatake A,Nakaya N,Sakata T,Shimada K,Shirato K,Matsuzawa Y,JELIS Investigators.

更新日期：2011-01-01 00:00:00

abstract：AIM:The levels of lipids, especially triglycerides (TG), and obesity are associated with diabetes mellitus (DM). Although typically measured in fasting individuals, non-fasting lipid measurements play an important role in predicting future DM. This study compared the predictive efficacy of lipid variables according to ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Fujihara K,Sugawara A,Heianza Y,Sairenchi T,Irie F,Iso H,Doi M,Shimano H,Watanabe H,Sone H,Ota H

更新日期：2014-01-01 00:00:00

abstract：:Due to the pandemics of obesity and diabetes mellitus, especially in the Western countries, atherosclerotic cardiovascular disease (ASCVD) has become a major health burden and is expected to increase in the future. Modifying lipid targets, especially low-density lipoprotein cholesterol (LDL-C) level, has become the fi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kataoka Y,Andrews J,Puri R,Psaltis P,Nicholls SJ

更新日期：2017-04-03 00:00:00

abstract：:Blood lipid levels are highly heritable and modifiable risk factors for coronary artery disease (CAD), and are the leading cause of death worldwide. These facts have motivated human genetic association studies that have the substantial potential to define the risk factors that are causal and to identify pathways and t...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tada H,Kawashiri MA,Konno T,Yamagishi M,Hayashi K

更新日期：2016-01-01 00:00:00

abstract：:The aim was to give on overview of the profile of cardiovascular disease, vascular pathology and the relationships between lifestyle and cardiovascular disease in Japanese. Compared with the United States and Europe, the higher mortality from stroke and lower mortality from coronary heart disease constitute a unique c...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iso H

更新日期：2011-01-01 00:00:00