Effect of the angiotensin II receptor antagonist telmisartan on lipoprotein lipase mass in preheparin serum.

abstract：AIM:To evaluate whether plaque scoring measurements are able to track changes in atherosclerotic plaque burden over time and to study whether this is affected by lipid-lowering therapy. METHODS:Data used were from METEOR (Measuring Effects on Intima-Media Thickness: an Evaluation Of Rosuvastatin), a randomized control...

journal_title：Journal of atherosclerosis and thrombosis

authors： Peters SA,Dogan S,Meijer R,Palmer MK,Grobbee DE,Crouse JR 3rd,O'Leary DH,Evans GW,Raichlen JS,Bots ML

更新日期：2011-01-01 00:00:00

abstract：AIM:A positive association between metabolic syndrome (MetS) and periodontal status has recently been noted. However, no study has evaluated the relationship by sex and in a general urban population using the uniform definition proposed in the 2009 Joint Interim Statement. The aim of this study was to clarify the relat...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kikui M,Kokubo Y,Ono T,Kida M,Kosaka T,Yamamoto M,Watanabe M,Maeda Y,Miyamoto Y

更新日期：2017-05-01 00:00:00

abstract：AIMS:Recently, a number of studies have shown an increased red blood cell distribution width (RDW) to be a strong and independent predictor of the prognosis of coronary artery disease. The aim of this study was to investigate the underlying mechanisms responsible for the relationship between the RDW and a poor prognosi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wang P,Wang Y,Li H,Wu Y,Chen H

更新日期：2015-01-01 00:00:00

abstract：AIM:Macrophage migration inhibitory factor (MIF) is known as a pro-inflammatory cytokine that regulates a broad spectrum of inflammatory reactions. MIF is expressed in vascular smooth muscle cells (VSMCs), and inhibition of the progression of atherosclerosis was observed in MIF-deficient atherosclerotic mice. However, ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okamoto T,Atsumi T,Shimizu C,Yoshioka N,Koike T

更新日期：2008-02-01 00:00:00

abstract：AIM:Although the InnovaTM self-expanding nitinol stent (Boston Scientific, Marlborough, MA) exhibits acceptable performance in long-term safety and efficacy when used for the treatment of femoropopliteal (FP) lesions, clinical outcomes following its implantation have not been systematically studied in real-world settin...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tsujimura T,Takahara M,Iida O,Hiramori S,Hayakawa N,Karashima E,Miura T,Teramura M,Ichihashi K,Kojima T,Aihara H,Yamaoka T,Fujihara M,Tosaka A,Doijiri T,Mano T,Soga Y

更新日期：2019-10-01 00:00:00

abstract：:Several reports have suggested that HDL has anti-oxidative actions. We investigated the relationship between HDL-cholesterol (HDL-C) and malondialdehyde-modified LDL (MDA-LDL) concentrations using enzyme linked immunosolvent assay. We divided our study subjects into four groups on the basis of concentrations of trigly...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kondo A,Li J,Manabe M,Saito K,Kanno T,Maekawa M

更新日期：2003-01-01 00:00:00

abstract：AIM:High density lipoprotein (HDL) and its apolipoproteins can promote cholesterol efflux from macrophage foam cells via the ATP-binding cassette transporter A1 (ABCA1), ABCG1, and scavenger receptor class B type I (SR-BI). Liver X receptors (LXRs) operate as cholesterol sensors which may protect from cholesterol overl...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hu YW,Wang Q,Ma X,Li XX,Liu XH,Xiao J,Liao DF,Xiang J,Tang CK

更新日期：2010-05-01 00:00:00

abstract：AIM:Since we previously reported that lower levels of HDL-C may be most useful for predicting coronary artery disease (CAD) as assessed by multi-detector row computed tomography (MDCT), we sought to confirm, among the levels of LDL-C, HDL-C, non-HDL-C (total cholesterol minus HDL-C) and the ratio of LDL-C to HDL-C (LDL...

journal_title：Journal of atherosclerosis and thrombosis

authors： Shiga Y,Miura S,Mitsutake R,Kawamura A,Uehara Y,Saku K

更新日期：2010-08-31 00:00:00

abstract：AIMS:Small arteries can be visualized in the ocular fundus, and findings of retinopathy based on Scheie classification are often applied to evaluate the impact of hypertension and atherosclerosis. However, the relationship between damage in the large and small arteries has not been investigated sufficiently, especially...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sugiura T,Dohi Y,Takagi Y,Yokochi T,Yoshikane N,Suzuki K,Tomiishi T,Nagami T,Iwase M,Takase H,Seo Y,Ohte N

更新日期：2020-11-25 00:00:00

abstract：AIM:This study tested the hypothesis that tacrolimus therapy limited left ventricular (LV) infarct and remodeling by suppressing the inflammatory response, oxidative stress and regulating the mitogen-activated protein kinase (MAPK) and Akt signaling pathways in an acute myocardial infarction (AMI) mini-pig model by lig...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yang CH,Sheu JJ,Tsai TH,Chua S,Chang LT,Chang HW,Lee FY,Chen YL,Chung SY,Sun CK,Leu S,Yen CH,Yip HK

更新日期：2013-01-01 00:00:00

abstract：AIM:Although current guidelines recommend surgical revascularization as the first-line therapy for chronic total occlusion of the abdominal aorta (Leriche syndrome), endovascular therapy (EVT) has been increasingly utilized because of the development of new technologies and techniques. EVT has demonstrated durable midt...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nanto K,Iida O,Fujihara M,Yokoi Y,Tomoi Y,Soga Y,Fujita M,Masuda M,Okamoto S,Ishihara T,Kanda T,Tsujimura T,Matsuda Y,Okuno S,Mano T

更新日期：2019-11-01 00:00:00

abstract：AIM:Carotid intima-media thickness (CIMT) measurements are used as a disease outcome in randomized controlled trials that assess the effects of lipid-modifying treatment. It is unclear whether common CIMT or mean maximum CIMT should be used as the primary outcome. We directly compared both measurements using aspects th...

journal_title：Journal of atherosclerosis and thrombosis

authors： Dogan S,Kastelein JJ,Grobbee DE,Bots ML

更新日期：2011-01-01 00:00:00

abstract：AIM:Associations between long-term exposure to particulate matter (PM) and increased cardiovascular mortality have been reported, but few studies have investigated the associated incidence of cardiovascular disease, and none involved men. METHODS:We used data on 78,057 participants (37,121 men, 40,936 women) to examin...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nishiwaki Y,Michikawa T,Takebayashi T,Nitta H,Iso H,Inoue M,Tsugane S,Japan Public Health Center-based Prospective Study Group.

更新日期：2013-01-01 00:00:00

abstract：AIM:This study aimed to examine whether cardiorespiratory fitness (CRF) is associated with arterial stiffening, evaluated using the cardio-ankle vascular index (CAVI), independent of visceral fat (VF) in middle-aged and elderly Japanese men. We also examined whether the relationship between CRF and the CAVI is modified...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tanisawa K,Ito T,Sun X,Kawakami R,Oshima S,Gando Y,Cao ZB,Sakamoto S,Higuchi M

更新日期：2015-01-01 00:00:00

abstract：:Rats with alloxan-induced diabetes developed severe atherosclerotic lesions when they were maintained on a 0.25% cholesterol diet for one year. The atheromatous changes developed at the aortic arch, appeared as early as 3 months after the start of the experiment, and increased thereafter. The diabetic rats also develo...

journal_title：Journal of atherosclerosis and thrombosis

authors： Uchida K,Takase H,Nomura Y,Nakamura Y,Igimi H,Takasu N,Kurihara H,Takeuchi N

更新日期：1994-01-01 00:00:00

abstract：AIM:Hypercholesterolemic patients with inflammation are at high risk for cardiovascular events. Statins exert anti-inflammatory action independent of their cholesterol-lowering action. This study sought to clarify whether statin therapy reduces inflammatory markers in hypercholesterolemic patients and to determine fact...

journal_title：Journal of atherosclerosis and thrombosis

authors： Horiuchi Y,Hirayama S,Soda S,Seino U,Kon M,Ueno T,Idei M,Hanyu O,Tsuda T,Ohmura H,Miida T

更新日期：2010-07-30 00:00:00

abstract：:Blood lipid levels are highly heritable and modifiable risk factors for coronary artery disease (CAD), and are the leading cause of death worldwide. These facts have motivated human genetic association studies that have the substantial potential to define the risk factors that are causal and to identify pathways and t...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tada H,Kawashiri MA,Konno T,Yamagishi M,Hayashi K

更新日期：2016-01-01 00:00:00

abstract：AIM:The association between urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), an oxidative stress marker, and the incidence of cardiovascular disease (CVD) has not been confirmed because no previous studies evaluated 24-hour 8-OHdG excretion levels in the general population. We aimed to confirm the association between 24-h...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nagao M,Kobashi G,Umesawa M,Cui R,Yamagishi K,Imano H,Okada T,Kiyama M,Kitamura A,Sairenchi T,Haruyama Y,Ohira T,Iso H,CIRCS Investigators.

更新日期：2020-10-01 00:00:00

abstract：AIM:To examine the association between renal vasculature changes and generalized atherosclerosis using autopsy cases. METHODS:We histologically examined 107 autopsy patients(mean age, 68.4 years; 64% men; 81% non-CVD) to investigate the association between renal vasculature changes and generalized atherosclerosis. We ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iwakiri T,Sato Y,Matsuura Y,Hatakeyama K,Marutsuka K,Yamashita A,Fujimoto S,Kitamura K,Asada Y

更新日期：2014-01-01 00:00:00

abstract：AIM:Atrial fibrillation (AF) is characterized by the development of thromboembolic events and is more prevalent among end-stage renal disease patients than in the general population. Vascular access thrombosis (VAT) is a major morbidity in chronic hemodialysis (HD) patients; however, the association between AF and VAT ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Chou CY,Chen JY,Liu JH,Liu YL,Lin HH,Yang YF,Wang SM,Kuo HL,Huang CC

更新日期：2011-01-01 00:00:00

abstract：AIM:Homocysteine is associated with increased arterial resistance and eventually causes luminal reduction. The purpose of the present study was to evaluate an association between the plasma concentration of total homocysteine (tHcy) and stenosis or occlusion of the internal carotid artery (ICA) in patients with ischemi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Jeong SK,Seo JY,Cho YI

更新日期：2010-09-30 00:00:00

abstract：AIMS:The identification and appropriate management of commercial motor vehicle (CMV) drivers with unrecognized obstructive sleep apnea (OSA) is a major public health concern and priority; OSA among drivers has not been fully investigated in Japan, and a better understanding of this undiagnosed disease is warranted. The...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ueyama M,Kokuto H,Sugihara H,Oikawa S,Suzuki F,Goto H,Kudoh S

更新日期：2018-11-01 00:00:00

abstract：AIMS:Statins not only reduce low-density lipoprotein (LDL) cholesterol, but also prevent the progression of kidney dysfunction. Ezetimibe, a cholesterol-absorption inhibitor, also lowers LDL cholesterol levels when added to statins; however, the effect of add-on ezetimibe on kidney function has had conflicting results....

journal_title：Journal of atherosclerosis and thrombosis

authors： Kinouchi K,Ichihara A,Bokuda K,Morimoto S,Itoh H

更新日期：2013-01-01 00:00:00

abstract：:Elevated resting heart rate (HR) is associated with hypertension in addition to or similar to increased incidence of cardiovascular morbidity and mortality. Subjects with high HR exhibit the characteristic features of insulin resistance syndrome. Sympathetic overactivity underlies this clinical condition. However, the...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hasegawa T,Watase H

更新日期：2003-01-01 00:00:00

abstract：:Statins are the main treatment for hypercholesterolemia and the cornerstone of atherosclerotic cardiovascular disease prevention. Many patients taking statins report muscle-related symptoms, one of the most important causes of statin treatment discontinuation, which is associated with an increased risk of cardiovascul...

journal_title：Journal of atherosclerosis and thrombosis

authors： Alonso R,Cuevas A,Cafferata A

更新日期：2019-03-01 00:00:00

abstract：:Recent findings suggest that the oxidative modification of low-density lipoproteins (LDL) and an increase in triglyceride-rich lipoprotein particles including chylomicron remnants contribute to the progression of atherosclerosis, as does the inflammatory response. We therefore examined whether and how these lipoprotei...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okumura T,Fujioka Y,Morimoto S,Masai M,Sakoda T,Tsujino T,Kashiwamura S,Okamura H,Ohyanagi M

更新日期：2006-02-01 00:00:00

abstract：:Generally, it is considered that visceral fat brings insulin resistance and hyper-insulinemia, in the mechanisms of metabolic syndromes. However, whether hyperinsulinemia brings about accumulation of visceral fat is not clear. We followed a case of insulinoma that caused primary hyperinsulinemia, and measured the chan...

journal_title：Journal of atherosclerosis and thrombosis

authors： Saiki A,Miyashita Y,Wakabayashi M,Kameda N,Shirai K

更新日期：2004-01-01 00:00:00

abstract：:We studied the association of six common polymorphisms of four genes related to lipid metabolism with serum lipid levels. We selected single-nucleotide polymorphisms (SNPs) in the genes for cholesteryl ester transfer protein (CETP), lipoprotein lipase (LPL), hepatic lipase (LIPC), and apolipoprotein CIII (APOC3), and ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Arai H,Yamamoto A,Matsuzawa Y,Saito Y,Yamada N,Oikawa S,Mabuchi H,Teramoto T,Sasaki J,Nakaya N,Itakura H,Ishikawa Y,Ouchi Y,Horibe H,Egashira T,Hattori H,Shirahashi N,Kita T

更新日期：2005-01-01 00:00:00

abstract：AIM:Was to evaluate the role of seven matrix metalloproteinase (MMP) polymorphisms in the genetic susceptibility to develop myocardial infarction in Mexican individuals. METHODS:Seven polymorphisms in the MMP genes were genotyped by 5' exonuclease TaqMan genotyping assays in 300 patients with myocardial infarction and...

journal_title：Journal of atherosclerosis and thrombosis

authors： Pérez-Hernández N,Vargas-Alarcón G,Martínez-Rodríguez N,Martínez-Ríos MA,Peña-Duque MA,Peña-Díaz Ade L,Valente-Acosta B,Posadas-Romero C,Medina A,Rodríguez-Pérez JM

更新日期：2012-01-01 00:00:00

abstract：AIM:Inherent mechanisms leading to vascular smooth muscle cells (VSMC) alterations in obesitylinked type 2 diabetes (T2D) situation remain to be clarified. This study evaluates the impact of supernatant of adipocytes extracted from mice fed high-fat-diets (HFD) on the proliferation and apoptosis of VSMC. METHODS:Adipo...

journal_title：Journal of atherosclerosis and thrombosis

authors： El Akoum S,Cloutier I,Tanguay JF

更新日期：2012-01-01 00:00:00