Abstract:
AIM:Atrial fibrillation (AF) is characterized by the development of thromboembolic events and is more prevalent among end-stage renal disease patients than in the general population. Vascular access thrombosis (VAT) is a major morbidity in chronic hemodialysis (HD) patients; however, the association between AF and VAT is unknown. METHODS:We retrospectively reviewed chronic HD patients with functional vascular access between 1997 and 2006. The association between AF and the development of VAT was analyzed using Kaplan-Meier analysis and multivariate Cox proportional hazards regression. RESULTS:A total of 568 chronic HD patients, including 55 (9.7%) patients with AF, were reviewed and 154 (27.1%) patients developed at least one episode of VAT. Patients with AF had worse VAT-free survival than patients without AF (p< 0.001). In Cox regression, age, type of vascular access, atrial fibrillation, diabetes, hypertension, and C-reactive protein were independently linked to the development of VAT ( p= 0.049, < 0.001, < 0.001, 0.001, 0.028 and 0.045). The hazard ratios were 2.1 (95% CI: 1.00-1.03) for arteriovenous graft, 2.47 (95% CI: 1.66-3.69) for AF, 1.72 (95% CI: 1.25-2.39) for diabetes and 1.09 (95% CI: 1.00-1.18) for serum C-reactive protein (every 1 mg/dL increase), respectively. CONCLUSION:Atrial fibrillaiton is linked to the development of vascular access thrombosis in chronic hemodialysis patients and is independent of traditional VAT risk factors.
journal_name
J Atheroscler Thrombjournal_title
Journal of atherosclerosis and thrombosisauthors
Chou CY,Chen JY,Liu JH,Liu YL,Lin HH,Yang YF,Wang SM,Kuo HL,Huang CCdoi
10.5551/jat.6296subject
Has Abstractpub_date
2011-01-01 00:00:00pages
448-53issue
6eissn
1340-3478issn
1880-3873pii
JST.JSTAGE/jat/6296journal_volume
18pub_type
杂志文章abstract:AIM:In addition to the risk of progression to end-stage renal disease (ESRD), chronic kidney disease (CKD) is also known to be associated with an elevated risk of cardiovascular disease (CVD). Statins may improve renal function in CKD patients. METHODS:The database of the LIVALO Effectiveness and Safety (LIVES) Study,...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.3764
更新日期:2010-06-30 00:00:00
abstract::Several reports have suggested that HDL has anti-oxidative actions. We investigated the relationship between HDL-cholesterol (HDL-C) and malondialdehyde-modified LDL (MDA-LDL) concentrations using enzyme linked immunosolvent assay. We divided our study subjects into four groups on the basis of concentrations of trigly...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.10.72
更新日期:2003-01-01 00:00:00
abstract:AIM:Patients with acute infectious diseases are at an increased risk of venous thromboembolism (VTE). Clinicians should be aware of the VTE risk in patients with COVID-19, many of whom present with severe coagulation disorders. METHOD:We used an online platform to conduct a cross-sectional questionnaire survey among d...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.58933
更新日期:2020-10-01 00:00:00
abstract:AIM:A novel device has been developed for measuring the cardio-ankle vascular index (CAVI) as an indicator of arterial stiffness. In this study, we evaluated the effect of pitavastatin on CAVI in type 2 diabetic patients. METHODS:Forty-five type 2 diabetes mellitus patients with low-density lipoprotein cholesterolemia...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章,随机对照试验
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更新日期:2009-10-01 00:00:00
abstract:AIM:Macrophage migration inhibitory factor (MIF) is known as a pro-inflammatory cytokine that regulates a broad spectrum of inflammatory reactions. MIF is expressed in vascular smooth muscle cells (VSMCs), and inhibition of the progression of atherosclerosis was observed in MIF-deficient atherosclerotic mice. However, ...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.e495
更新日期:2008-02-01 00:00:00
abstract:AIM:To assess the long-term effects of intracoronary stem cell (SC) infusion following acute myocardial infarction (AMI) on the local atherosclerotic process at the site of infusion after four years of follow-up. METHODS:We evaluated 18 post-AMI patients. Group 1 consisted of nine patients given an intracoronary injec...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.19745
更新日期:2014-01-01 00:00:00
abstract:AIM:The risk index for atherosclerotic cardiovascular diseases in the Japanese metabolic syndrome-focused health checkup program was changed from total cholesterol (TC) to low-density lipoprotein cholesterol (LDL-C). We discuss the validity of this change with respect to standardization. METHODS:The beta-quantificatio...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.5470
更新日期:2010-12-26 00:00:00
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journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章,多中心研究
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更新日期:2019-11-01 00:00:00
abstract:AIMS:Hypertrophied hearts at autopsy often display excessive coronary artery atherosclerosis, but the histopathology of coronary arteries in hearts with and without cardiomegaly has rarely been compared. METHODS:In this study, forensic autopsies provided hearts with unexplained enlargement plus comparison specimens. R...
journal_title:Journal of atherosclerosis and thrombosis
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更新日期:2011-01-01 00:00:00
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journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
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更新日期:2010-05-01 00:00:00
abstract::A number of effective drugs have been developed through animal experiments, contributing to the health of many patients. In particular, the WHHL rabbit family (WHHL rabbits and its advanced strains (coronary atherosclerosis-prone WHHL-CA rabbits and myocardial infarction-prone WHHLMI rabbits) developed at Kobe Univers...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 历史文章,杂志文章
doi:10.5551/jat.RV17038-2
更新日期:2020-02-01 00:00:00
abstract:AIM:To develop and validate a new risk prediction model for predicting the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) in Japanese adults. METHODS:A total of 2,454 participants aged 40-84 years without a history of cardiovascular disease (CVD) were prospectively followed up for 24 years. An incident...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.61960
更新日期:2021-01-22 00:00:00
abstract:AIM:Endothelial dysfunction is considered an early event in the development of atherosclerosis. The present study was undertaken to determine whether the accumulation of cardiovascular risk factors and insulin resistance are associated with endothelial function in diabetic patients. METHODS:101 patients with type 2 di...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.e525
更新日期:2007-12-01 00:00:00
abstract::Cardiovascular disease constitutes the major cause of mortality in patients with chronic kidney disease. Arterial stiffness is an important contributor to the occurrence and progression of cardiovascular disease. Various risk factors, including altered hormone levels, have been suggested to be associated with arterial...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章,评审
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更新日期:2013-01-01 00:00:00
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journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章,随机对照试验
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更新日期:2012-01-01 00:00:00
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journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
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更新日期:2009-01-01 00:00:00
abstract:AIM:In animals, dietary energy restriction is reported to increase longevity, whereas in humans, all cohort studies from Western countries have not shown an association between the low energy intake and longevity. We examined the association between total energy intake and longevity in Japan where dietary pattern is di...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.29991
更新日期:2016-01-01 00:00:00
abstract:AIM:The ankle-brachial index(ABI) is an easy-to-use, non-invasive and reliable diagnostic tool for assessing peripheral arterial occlusive disease(PAOD). The CHADS2(congestive heart failure, hypertension, age ≧75 years, diabetes, prior stroke) score is a simple and popular clinical parameter that is used to assess the ...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.21212
更新日期:2014-01-01 00:00:00
abstract::In atherosclerotic lesions, matrix metalloproteinases produced by foam cells (macrophages) are thought to increase plaque instability, promote plaque rupture, by degradating extracellular matrix. To investigate the relationship between the expression of these proteinases and the histologic appearance of atheromas, imm...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat1994.8.50
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abstract:AIM:We investigated the effects of a calorie-restricted low-carbohydrate diet on glucose and lipid metabolism, and body fat distribution, especially on the secretion of leptin and lipoprotein lipase from adipose tissue in Otsuka Long Evans Tokushima Fatty (OLETF) rats. METHODS:Forty-three week-old male OLETF rats were...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.5551/jat.5579
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更新日期:2017-01-01 00:00:00
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journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
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更新日期:2010-05-01 00:00:00
abstract:AIM:The adipocyte-derived hormone leptin plays a key role in the regulation of food intake and energy expenditure. Recent studies have suggested that leptin is also involved in the pathogenesis of obesity-associated atherosclerosis and cardiovascular disease. In this study, we investigated the associations of leptin an...
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更新日期:2013-01-01 00:00:00
abstract:AIM:The Framingham risk score (FRS) is one of the standard tools used to predict the incidence of coronary heart disease (CHD). No previous study has investigated its efficacy for a Japanese population cohort. The purpose of this study was to develop new coronary prediction algorithms for the Japanese population in the...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章,随机对照试验
doi:10.5551/jat.19356
更新日期:2014-01-01 00:00:00
abstract::Even though it is only a little over a decade from the discovery of proprotein convertase subtilisin/kexin type 9 (PCSK9) as a plasma protein that associates with both high and low cholesterol syndromes, a rich body of knowledge has developed, and drugs inhibiting this target have been approved in many markets. While ...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章,评审
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更新日期:2017-05-01 00:00:00
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journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.45344
更新日期:2019-03-01 00:00:00
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journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
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更新日期:2011-01-01 00:00:00
abstract:AIM:Children exposed to parental smoking are at increased long-term risk of subclinical atherosclerosis in adulthood. However, it has not been quantified if exposure to parental smoking in childhood is associated with adult systemic inflammation. This study aimed to determine if childhood exposure to parental smoking w...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章
doi:10.5551/jat.40568
更新日期:2017-12-01 00:00:00
abstract::Calcium deposits account for most of the dry weight of atherosclerotic lesions. Previously considered uncommon, vascular calcification is now known to be present in 80% of significant lesions and in at least 90% of patients with coronary artery disease. Previously considered a passive process, it is increasingly recog...
journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章,评审
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更新日期:1996-01-01 00:00:00