Association between abdominal wall fat index and carotid atherosclerosis in women.

abstract：AIMS:Profiling of lipoproteins can predict risk of cardiovascular disease; gel permeation high-performance liquid chromatography (HPLC) improves prediction accuracy by providing detailed data for specific lipoprotein subclasses. This study applied HPLC to examine the effects of evolocumab, which effectively treats hype...

journal_title：Journal of atherosclerosis and thrombosis

authors： Masuda D,Kiyosue A,Hirayama A,Shimauchi J,López JAG,Miyawaki K,Yamashita S

更新日期：2020-11-01 00:00:00

abstract：:The signaling and functions of the Endothelial Differentiation Gene (EDG) family of G protein-coupled receptors have been extensively elucidated. All the members of EDG family were shown to be receptors for lysosphingolipids or lysophospholipids. EDG-1, the prototype of EDG family receptors, is a high affinity recepto...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ozaki H,Hla T,Lee MJ

更新日期：2003-01-01 00:00:00

abstract：AIM:Homocysteine is associated with increased arterial resistance and eventually causes luminal reduction. The purpose of the present study was to evaluate an association between the plasma concentration of total homocysteine (tHcy) and stenosis or occlusion of the internal carotid artery (ICA) in patients with ischemi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Jeong SK,Seo JY,Cho YI

更新日期：2010-09-30 00:00:00

abstract：AIM:The risk index for atherosclerotic cardiovascular diseases in the Japanese metabolic syndrome-focused health checkup program was changed from total cholesterol (TC) to low-density lipoprotein cholesterol (LDL-C). We discuss the validity of this change with respect to standardization. METHODS:The beta-quantificatio...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nakamura M,Koyama I,Iso H,Sato S,Okazaki M,Kayamori Y,Kiyama M,Kitamura A,Shimamoto T,Ishikawa Y

更新日期：2010-12-26 00:00:00

abstract：AIM:Increasing evidence indicates that antimicrobial peptides, human neutrophil peptide-1, -2, and -3 (HNP1-3) and human antimicrobial peptide LL-37 are involved in the pathophysiology of atherosclerosis; however, little is known about their circulating protein levels in acute myocardial infarction (AMI). We therefore ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Zhao H,Yan H,Yamashita S,Li W,Liu C,Chen Y,Zhou P,Chi Y,Wang S,Zhao B,Song L

更新日期：2012-01-01 00:00:00

abstract：AIM:Resistin is an adipocytokine that may link inflammation and atherosclerosis.We studied the associations of resistin levels with cardiovascular events and restenosis. METHODS:We measured pre-procedural serum resistin levels in 140 patients with coronary artery disease undergoing elective percutaneous coronary inter...

journal_title：Journal of atherosclerosis and thrombosis

authors： Momiyama Y,Ohmori R,Uto-Kondo H,Tanaka N,Kato R,Taniguchi H,Arakawa K,Nakamura H,Ohsuzu F

更新日期：2011-01-01 00:00:00

abstract：:Vascular calcification is a common feature of advanced atherosclerosis resulting in reduced elasticity of elastic arteries. However, the relationship between elastic fibers and vascular calcification at the molecular and cellular levels remains unknown. We investigated the expression of major elastic fiber components ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sugitani H,Wachi H,Mecham RP,Seyama Y

更新日期：2002-01-01 00:00:00

abstract：AIM:Myriad biological effects of leptin may lead to broad therapeutic applications for various metabolic diseases, including diabetes and its complications; however, in contrast to its anorexic effect, the molecular mechanisms underlying adipopenic and glucose-lowering effects of leptin have not been fully understood. ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Takanashi M,Taira Y,Okazaki S,Takase S,Kimura T,Li CC,Xu PF,Noda A,Sakata I,Kumagai H,Ikeda Y,Iizuka Y,Yahagi N,Shimano H,Osuga JI,Ishibashi S,Kadowaki T,Okazaki H

更新日期：2017-11-01 00:00:00

abstract：AIM:It remains uncertain whether chronic exposure to particulate air pollution is associated with increased mortality in Japan because Japan has a different distribution pattern of cardiovascular disease and its risk factors compared to Western countries. We investigated the association between long-term exposure to pa...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ueda K,Nagasawa SY,Nitta H,Miura K,Ueshima H,NIPPON DATA80 Research Group.

更新日期：2012-01-01 00:00:00

abstract：AIM:The Vietnamese develop type 2 diabetes (T2D) and metabolic syndrome (MS) at a lower BMI than other ethnicities. Thus, biomarkers that identify subjects at an increased risk of T2D independently of obesity are being sought. Recent studies show that circulating NO metabolites (NOx) are increased in T2D. We investigat...

journal_title：Journal of atherosclerosis and thrombosis

authors： Binh PN,Abe Y,Tien PG,Son le NT,Hanh TT,Diep do TN,Qui le TK,Kawano M,Maruyama C

更新日期：2011-01-01 00:00:00

abstract：:Macrophage or macrophage-derived foam cell death is one of the characteristic events in the development of cell-poor lipid-rich cores of the advanced atherosclerotic plaques. Although the in vivo mechanism for the death of macrophages is unclear, one possible candidate for the agent which induces macrophage cell death...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hakamata H,Miyazaki A,Sakai M,Sakamoto YI,Horiuchi S

更新日期：1998-01-01 00:00:00

abstract：AIM:Smoking induces vascular inflammation and increases the risk of cardiovascular events. Lectinlike oxidized low-density lipoprotein receptor-1 (LOX-1) is a scavenger receptor that is induced by oxidative stress and is associated with atherosclerotic plaque formation and destabilization. LOX-1 interacts with C-reacti...

journal_title：Journal of atherosclerosis and thrombosis

authors： Takanabe-Mori R,Ono K,Wada H,Takaya T,Ura S,Yamakage H,Satoh-Asahara N,Shimatsu A,Takahashi Y,Fujita M,Fujita Y,Sawamura T,Hasegawa K

更新日期：2013-01-01 00:00:00

abstract：AIM:Moderate alcohol consumption appears to confer some protection against coronary heart disease, which is related to an increase in high-density lipoprotein cholesterol (HDL-C). The genotype of aldehyde dehydrogenase 2 (ALDH2) is closely related to alcohol metabolism but a relationship between ALDH2 genotypes and HDL...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wada M,Daimon M,Emi M,Iijima H,Sato H,Koyano S,Tajima K,Kawanami T,Kurita K,Hunt SC,Hopkins PN,Kubota I,Kawata S,Kato T

更新日期：2008-08-01 00:00:00

abstract：AIM:The purpose of this study is to investigate the impact of arterial stiffness assessed using Cardio-ankle Vascular Index (CAVI) on long-term outcome after acute coronary syndrome (ACS). METHODS:A total of 387 consecutive patients (324 males; age, 64±11 years) with ACS were enrolled. We examined CAVI and brachial-an...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kirigaya J,Iwahashi N,Tahakashi H,Minamimoto Y,Gohbara M,Abe T,Akiyama E,Okada K,Matsuzawa Y,Maejima N,Hibi K,Kosuge M,Ebina T,Tamura K,Kimura K

更新日期：2020-07-01 00:00:00

abstract：AIM:Atrial fibrillation (AF) is characterized by the development of thromboembolic events and is more prevalent among end-stage renal disease patients than in the general population. Vascular access thrombosis (VAT) is a major morbidity in chronic hemodialysis (HD) patients; however, the association between AF and VAT ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Chou CY,Chen JY,Liu JH,Liu YL,Lin HH,Yang YF,Wang SM,Kuo HL,Huang CC

更新日期：2011-01-01 00:00:00

abstract：:Oxidative stress induced by reactive oxygen species (ROS) plays an important role in atherogenesis, and the redox state is determined by the balance between antioxidants and the ROS generating system. To defend against enhanced ROS, mammalian cells have a complex network of antioxidant enzymes such as superoxide dismu...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kobayashi S,Inoue N,Azumi H,Seno T,Hirata K,Kawashima S,Hayashi Y,Itoh H,Yokozaki H,Yokoyama M

更新日期：2002-01-01 00:00:00

abstract：AIM:Lipoprotein lipase protein exists in preheparin serum (preheparin LpL mass), even though lipoprotein lipase activity is rarely detected. Recent clinical studies have clarified that low preheparin LpL mass concentration is an important coronary risk factor. The aim of this study was to clarify the effect of telmisar...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hitsumoto T,Takahashi M,Iizuka T,Shirai K

更新日期：2008-06-01 00:00:00

abstract：AIMS:Cardiovascular disease (CVD) remains the leading cause of death worldwide despite improvements in the treatment of atherosclerosis, an inflammatory disease and major underlying cause of CVD. Monocytes, an innate immune cell type, are linked to CVD progression; however, given their heterogeneity, the association be...

journal_title：Journal of atherosclerosis and thrombosis

authors： SahBandar IN,Ndhlovu LC,Saiki K,Kohorn LB,Peterson MM,D'Antoni ML,Shiramizu B,Shikuma CM,Chow DC

更新日期：2020-05-01 00:00:00

abstract：:Normal and alloxan diabetic rats were kept on a 0.25% cholesterol diet for 12 months and the changes in serum cholesterol levels, and fecal excretion of sterols and bile acids were examined to elucidate the influence of changes in bile acid metabolism on manifestations of hypercholesterolemia and development of athero...

journal_title：Journal of atherosclerosis and thrombosis

authors： Uchida K,Satoh T,Takase H,Nomura Y,Takasu N,Kurihara H,Takeuchi N

更新日期：1996-01-01 00:00:00

abstract：:We studied the association of six common polymorphisms of four genes related to lipid metabolism with serum lipid levels. We selected single-nucleotide polymorphisms (SNPs) in the genes for cholesteryl ester transfer protein (CETP), lipoprotein lipase (LPL), hepatic lipase (LIPC), and apolipoprotein CIII (APOC3), and ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Arai H,Yamamoto A,Matsuzawa Y,Saito Y,Yamada N,Oikawa S,Mabuchi H,Teramoto T,Sasaki J,Nakaya N,Itakura H,Ishikawa Y,Ouchi Y,Horibe H,Egashira T,Hattori H,Shirahashi N,Kita T

更新日期：2005-01-01 00:00:00

abstract：AIM:This study aimed to examine whether cardiorespiratory fitness (CRF) is associated with arterial stiffening, evaluated using the cardio-ankle vascular index (CAVI), independent of visceral fat (VF) in middle-aged and elderly Japanese men. We also examined whether the relationship between CRF and the CAVI is modified...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tanisawa K,Ito T,Sun X,Kawakami R,Oshima S,Gando Y,Cao ZB,Sakamoto S,Higuchi M

更新日期：2015-01-01 00:00:00

abstract：AIM:Increased levels of small dense low-density lipoproteins (sd-LDL) have been reported more atherogenic compared to total low-density lipoprotein (LDL); however, no definitive experiments using macrophages have examined this concept in vitro. METHOD AND RESULT:In this study, we isolated fractions of total LDL (densi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tani M,Kawakami A,Mizuno Y,Imase R,Ito Y,Kondo K,Ishii H,Yoshida M

更新日期：2011-01-01 00:00:00

abstract：AIM:The aim of the current study was to investigate circulating adiponectin levels and their associated factors in young lean healthy Japanese women. METHODS:We recruited 82 healthy Japanese women in their twenties and thirties with their body mass index <25 kg/m(2), and performed anthropometric, sphygmomanometric, an...

journal_title：Journal of atherosclerosis and thrombosis

authors： Takahara M,Katakami N,Kishida K,Kaneto H,Funahashi T,Shimomura I,Matsunaga S,Kubo S,Fukamizu H,Otsuka A,Ichihara K,Nakamura T

更新日期：2013-01-01 00:00:00

abstract：AIM:Recent evidence suggests that small dense low-density lipoprotein (sd-LDL) particles are more atherogenic than large-LDL in spite of their lower cholesterol content. This study aimed to determine whether sd-LDL-cholesterol (sd-LDL-C) is superior to LDL-C as a biomarker of coronary heart disease (CHD). METHODS:LDL ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Koba S,Yokota Y,Hirano T,Ito Y,Ban Y,Tsunoda F,Sato T,Shoji M,Suzuki H,Geshi E,Kobayashi Y,Katagiri T

更新日期：2008-10-01 00:00:00

abstract：AIM:The Japan Atherosclerosis Society Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases 2012 (JAS Guidelines 2012) indicate that the management target for serum non-high-density lipoprotein cholesterol (non-HDLC) level is 30 mg/dL higher than that for low-density lipoprotein cholest...

journal_title：Journal of atherosclerosis and thrombosis

authors： Saiki Y,Otsuka T,Kato K,Kawada T

更新日期：2016-01-01 00:00:00

abstract：AIM:Evidence is lacking about whether urinary stones are associated with the subsequent risk of cardiovascular diseases. Herein, we investigated the association between history of urinary stones and the risk of coronary heart disease (CHD) and stroke among middle-aged Japanese. METHODS:This cohort study included 89,03...

journal_title：Journal of atherosclerosis and thrombosis

authors： Arafa A,Eshak ES,Iso H,Shirai K,Muraki I,Sawada N,Tsugane S,JPHC Study Group.

更新日期：2020-11-01 00:00:00

abstract：:A number of effective drugs have been developed through animal experiments, contributing to the health of many patients. In particular, the WHHL rabbit family (WHHL rabbits and its advanced strains (coronary atherosclerosis-prone WHHL-CA rabbits and myocardial infarction-prone WHHLMI rabbits) developed at Kobe Univers...

journal_title：Journal of atherosclerosis and thrombosis

authors： Shiomi M

更新日期：2020-02-01 00:00:00

abstract：:The aim of this study was to observe the efficacy of atorvastatin and the related factors of meeting the National Cholesterol Education Program (NCEP)-recommended low-density lipoprotein (LDL) cholesterol levels in patients with hypercholesterolemia. A total of 107 patients were treated with atorvastatin 10 mg/day for...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yoshitomi Y,Tsujibayashi T,Ishii T,Sakurai S,Nagakura C,Miyauchi A,National Cholesterol Education Program.

更新日期：2003-01-01 00:00:00

abstract：AIM:Children exposed to parental smoking are at increased long-term risk of subclinical atherosclerosis in adulthood. However, it has not been quantified if exposure to parental smoking in childhood is associated with adult systemic inflammation. This study aimed to determine if childhood exposure to parental smoking w...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wang D,Juonala M,Viikari JSA,Wu F,Hutri-Kähönen N,Raitakari OT,Magnussen CG

更新日期：2017-12-01 00:00:00

abstract：AIM:We focused on the ratios of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) to arachidonic acid (AA) and explored the significance of these ratios relative to clinical characteristics by age in ischemic stroke patients. METHODS:We enrolled patients with acute ischemic stroke who underwent radiological i...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ueno Y,Tanaka R,Yamashiro K,Miyamoto N,Hira K,Kurita N,Sakurai M,Urabe T,Shimada K,Miyazaki T,Daida H,Hattori N

更新日期：2018-07-01 00:00:00