Expressional changes of the vascular antioxidant system in atherosclerotic coronary arteries.

abstract：AIM:This study was designed to analyze microparticles (MPs) from endothelial cells (EMPs) and immune cells from healthy individuals and paitents with Takayasu arteritis (TA), and any possible relationships between MPs and TA acitivity. METHODS:MPs derived from the plasma of 51 subjects were analyzed, including 32 pati...

journal_title：Journal of atherosclerosis and thrombosis

authors： Cheng X,Dang A,Lv N,Zhao T

更新日期：2019-06-01 00:00:00

abstract：AIM:There are few data regarding associations between sleep duration and subclinical atherosclerosis in Japan. The aim of this study was to evaluate associations of self-reported sleep duration with calcification in the coronary arteries (CAC) and carotid intima media thickness (IMT) in Japanese men. METHODS:This was ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Suzuki S,Arima H,Miyazaki S,Fujiyoshi A,Kadota A,Takashima N,Hisamatsu T,Kadowaki S,Zaid M,Torii S,Horie M,Murata K,Miura K,Ueshima H,SESSA Research Group.

更新日期：2018-02-01 00:00:00

abstract：:The constellation of metabolic abnormalities including centrally distributed obesity, decreased high-density lipoprotein cholesterol (HDL-C), elevated triglycerides, elevated blood pressure (BP), and hyperglycaemia is known as the metabolic syndrome. Associated with a 3 fold and 2 fold increase in type 2 diabetes and ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Zimmet P,Magliano D,Matsuzawa Y,Alberti G,Shaw J

更新日期：2005-01-01 00:00:00

abstract：AIM:Withholding effective treatment is clinically prevalent. The CEntralized Pan-Asian survey on tHE Under-treatment of hypercholeSterolemia (CEPHEUS-PA) indicated suboptimal low-density lipoprotein cholesterol (LDL-C) goal attainment in Taiwan, which may be attributable to clinical inertia. We herein analyzed the Taiw...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wang KL,Wu CH,Wang KF,Chang CC,Chen LC,Lu TM,Lin SJ,Chiang CE

更新日期：2014-01-01 00:00:00

abstract：AIM:A novel device has been developed for measuring the cardio-ankle vascular index (CAVI) as an indicator of arterial stiffness. In this study, we evaluated the effect of pitavastatin on CAVI in type 2 diabetic patients. METHODS:Forty-five type 2 diabetes mellitus patients with low-density lipoprotein cholesterolemia...

journal_title：Journal of atherosclerosis and thrombosis

authors： Miyashita Y,Endo K,Saiki A,Ban N,Yamaguchi T,Kawana H,Nagayama D,Ohira M,Oyama T,Shirai K

更新日期：2009-10-01 00:00:00

abstract：:Blood lipid levels are highly heritable and modifiable risk factors for coronary artery disease (CAD), and are the leading cause of death worldwide. These facts have motivated human genetic association studies that have the substantial potential to define the risk factors that are causal and to identify pathways and t...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tada H,Kawashiri MA,Konno T,Yamagishi M,Hayashi K

更新日期：2016-01-01 00:00:00

abstract：:Cell degeneration and collagenosis are the main features in atherosclerotic plaque. We examined the effects of human low density lipoprotein (LDL) on cultured rabbit aortic smooth muscle cells (SMCs). Copper oxidized LDL (LDL+Cu) injured the SMCs more than did native LDL. Cytotoxicity of oxidized LDL was prevented by ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Jimi S,Sakata N,Takebayashi S

更新日期：1994-01-01 00:00:00

abstract：AIM:We have conducted medical surveys on two Japanese populations (Japanese Americans living in the US and native Japanese living in Japan) to investigate the impact of westernization of lifestyles on diseases in Japanese people. A 1998 survey revealed that the progression of carotid intima-media wall thickness (IMT) w...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kubota M,Yoneda M,Watanabe H,Egusa G

更新日期：2017-10-01 00:00:00

abstract：AIM:Speckle-tracking imaging has been introduced for the precise assessment of vessel mechanics. However, there are no data on the role of this imaging tool in assessing the changes in vasculature with statin therapy, which is known to enhance vascular elasticity. METHODS:This study was a prospective study including 4...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hae Kim C,Wang S,Park JB,Jung KH,E Yoon Y,Lee SP,Kim HK,Kim YJ,Cho GY,Sohn DW

更新日期：2018-11-01 00:00:00

abstract：AIM:A positive association between metabolic syndrome (MetS) and periodontal status has recently been noted. However, no study has evaluated the relationship by sex and in a general urban population using the uniform definition proposed in the 2009 Joint Interim Statement. The aim of this study was to clarify the relat...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kikui M,Kokubo Y,Ono T,Kida M,Kosaka T,Yamamoto M,Watanabe M,Maeda Y,Miyamoto Y

更新日期：2017-05-01 00:00:00

abstract：AIM:To investigatethe association of plasma epoxyeicosatrienoic acids (EETs) with early neurologic deterioration (END), and whether EETs are mediated by EPHX2 variants in patients with minor ischemic stroke (MIS). METHOD:This was a prospective, multi-center observational study in patients with acute MIS in the Chinese...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yi X,Lin J,Li J,Zhou Q,Han Z

更新日期：2017-12-01 00:00:00

abstract：AIM:Both vascular function and structure are independent predictors of cardiovascular events. The purpose of this study was to evaluate vascular function and structure of a leg artery in patients with peripheral artery disease (PAD). METHODS:We measured flow-mediated vasodilatation (FMD) and nitroglycerine-induced vas...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iwamoto A,Kajikawa M,Maruhashi T,Iwamoto Y,Oda N,Kishimoto S,Matsui S,Kihara Y,Chayama K,Goto C,Noma K,Aibara Y,Nakashima A,Higashi Y

更新日期：2016-11-01 00:00:00

abstract：AIMS:Renal dysfunction is a major public health problem, but there have been few investigations of the relationship between serum high molecular weight (HMW) adiponectin and renal function in Japanese community-dwelling adults. METHODS:We randomly recruited a sample of 1,849 adult Japanese (793 men aged 60 ± 14 (mean ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kawamoto R,Tabara Y,Kohara K,Miki T,Abe M,Kusunoki T,Katoh T,Ohtsuka N

更新日期：2010-11-27 00:00:00

abstract：AIM:The purpose of this study was to evaluate the efficacy and safety of LIVALO tablets (pitavastatin) in Japanese male children with heterozygous familial hypercholesterolemia (FH). METHODS:A multicenter, randomized, double-blind, parallel study was conducted in 14 male children 10-15 years of age with heterozygous F...

journal_title：Journal of atherosclerosis and thrombosis

authors： Harada-Shiba M,Arisaka O,Ohtake A,Okada T,Suganami H,NK-104-PH 01 study registration group.

更新日期：2016-01-01 00:00:00

abstract：:Recent evidence suggests important roles for platelet activation in the progression of atherosclerosis. We have recently shown that P-selectin expression or the presence of platelet-monocyte aggregates, a well-characterized marker of platelet activation, is associated with carotid atherosclerosis in the general popula...

journal_title：Journal of atherosclerosis and thrombosis

authors： Shoji T,Koyama H,Fukumoto S,Maeno T,Yokoyama H,Shinohara K,Emoto M,Shoji T,Inaba M,Nishizawa Y

更新日期：2005-01-01 00:00:00

abstract：AIM AND METHODS:The high-density lipoprotein 2 cholesterol (HDL2-C) to HDL3-C ratio is associated with insulin resistance, high-molecular-weight adiponectin (HMW-Ad), and metabolic syndrome (MetS) components and is useful for evaluating MetS in Japanese individuals. We investigated potential associations between change...

journal_title：Journal of atherosclerosis and thrombosis

authors： Moriyama K,Takahashi E

更新日期：2016-06-01 00:00:00

abstract：AIM:To examine the association between renal vasculature changes and generalized atherosclerosis using autopsy cases. METHODS:We histologically examined 107 autopsy patients(mean age, 68.4 years; 64% men; 81% non-CVD) to investigate the association between renal vasculature changes and generalized atherosclerosis. We ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iwakiri T,Sato Y,Matsuura Y,Hatakeyama K,Marutsuka K,Yamashita A,Fujimoto S,Kitamura K,Asada Y

更新日期：2014-01-01 00:00:00

abstract：AIM:To evaluate the effect of statin therapy on the decrease of common carotid artery intima-media thickness (CCA-IMT) compared to placebo or usual care. METHODS:A systematic search of electronic databases (MEDLINE, EMBASE, and Cochrane Center Register) up to December 2011 was performed. Two reviewers independently de...

journal_title：Journal of atherosclerosis and thrombosis

authors： Huang Y,Li W,Dong L,Li R,Wu Y

更新日期：2013-01-01 00:00:00

abstract：AIMS:Statins not only reduce low-density lipoprotein (LDL) cholesterol, but also prevent the progression of kidney dysfunction. Ezetimibe, a cholesterol-absorption inhibitor, also lowers LDL cholesterol levels when added to statins; however, the effect of add-on ezetimibe on kidney function has had conflicting results....

journal_title：Journal of atherosclerosis and thrombosis

authors： Kinouchi K,Ichihara A,Bokuda K,Morimoto S,Itoh H

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study was to observe the efficacy of atorvastatin and the related factors of meeting the National Cholesterol Education Program (NCEP)-recommended low-density lipoprotein (LDL) cholesterol levels in patients with hypercholesterolemia. A total of 107 patients were treated with atorvastatin 10 mg/day for...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yoshitomi Y,Tsujibayashi T,Ishii T,Sakurai S,Nagakura C,Miyauchi A,National Cholesterol Education Program.

更新日期：2003-01-01 00:00:00

abstract：:Both hyperthyroidism and hypothyroidism affect the cardiovascular system. Hypothyroidism is known to be associated with enhanced atherosclerosis and ischemic heart diseases. The accelerated atherosclerosis in the hypothyroid state has been traditionally ascribed to atherogenic lipid profile, diastolic hypertension, an...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ichiki T

更新日期：2016-01-01 00:00:00

abstract：AIM:Epicardial adipose tissue (EAT) may be associated with arrhythmogenesis. P-wave indices such as P-wave dispersion and P-wave variation indicated a slowed conduction velocity within the atria. This study investigated the effect of dapagliflozin on EAT volume and P-wave indices. METHODS:In the present ad hoc analysi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sato T,Aizawa Y,Yuasa S,Fujita S,Ikeda Y,Okabe M

更新日期：2020-12-01 00:00:00

abstract：:Calcium deposits account for most of the dry weight of atherosclerotic lesions. Previously considered uncommon, vascular calcification is now known to be present in 80% of significant lesions and in at least 90% of patients with coronary artery disease. Previously considered a passive process, it is increasingly recog...

journal_title：Journal of atherosclerosis and thrombosis

authors： Parhami F,Boström K,Watson K,Demer LL

更新日期：1996-01-01 00:00:00

abstract：:Normal and alloxan diabetic rats were kept on a 0.25% cholesterol diet for 12 months and the changes in serum cholesterol levels, and fecal excretion of sterols and bile acids were examined to elucidate the influence of changes in bile acid metabolism on manifestations of hypercholesterolemia and development of athero...

journal_title：Journal of atherosclerosis and thrombosis

authors： Uchida K,Satoh T,Takase H,Nomura Y,Takasu N,Kurihara H,Takeuchi N

更新日期：1996-01-01 00:00:00

abstract：AIM:Although current guidelines recommend surgical revascularization as the first-line therapy for chronic total occlusion of the abdominal aorta (Leriche syndrome), endovascular therapy (EVT) has been increasingly utilized because of the development of new technologies and techniques. EVT has demonstrated durable midt...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nanto K,Iida O,Fujihara M,Yokoi Y,Tomoi Y,Soga Y,Fujita M,Masuda M,Okamoto S,Ishihara T,Kanda T,Tsujimura T,Matsuda Y,Okuno S,Mano T

更新日期：2019-11-01 00:00:00

abstract：AIM:To investigate the association between arterial stiffness (present with brachial-ankle pulse wave velocity (baPWV)) and metabolic syndrome (MetS) in a population-based study of middle-aged Chinese. METHODS:MetS was defined using the AHA/NHLBI criteria. A total of 1,018 subjects aged 40 years and over were recruite...

journal_title：Journal of atherosclerosis and thrombosis

authors： Lin WY,Lai MM,Li CI,Lin CC,Li TC,Chen CC,Lin T,Liu CS

更新日期：2009-04-01 00:00:00

abstract：AIM:Carotid intima-media thickness (CIMT) measurements are used as a disease outcome in randomized controlled trials that assess the effects of lipid-modifying treatment. It is unclear whether common CIMT or mean maximum CIMT should be used as the primary outcome. We directly compared both measurements using aspects th...

journal_title：Journal of atherosclerosis and thrombosis

authors： Dogan S,Kastelein JJ,Grobbee DE,Bots ML

更新日期：2011-01-01 00:00:00

abstract：AIM:The Japan EPA Lipid Intervention Study (JELIS) reported a 19% reduction of the risk for coronary artery disease after long-term use of pure eicosapentaenoic acid (EPA) in Japanese patients with hypercholesterolemia. The variation in plasma fatty acid composition influenced the risk of coronary events. The aim of th...

journal_title：Journal of atherosclerosis and thrombosis

authors： Itakura H,Yokoyama M,Matsuzaki M,Saito Y,Origasa H,Ishikawa Y,Oikawa S,Sasaki J,Hishida H,Kita T,Kitabatake A,Nakaya N,Sakata T,Shimada K,Shirato K,Matsuzawa Y,JELIS.

更新日期：2012-01-01 00:00:00

abstract：:Statins are the main treatment for hypercholesterolemia and the cornerstone of atherosclerotic cardiovascular disease prevention. Many patients taking statins report muscle-related symptoms, one of the most important causes of statin treatment discontinuation, which is associated with an increased risk of cardiovascul...

journal_title：Journal of atherosclerosis and thrombosis

authors： Alonso R,Cuevas A,Cafferata A

更新日期：2019-03-01 00:00:00

abstract：:Patients with chronic kidney disease (CKD) are at an increased risk not only for end-stage kidney disease (ESKD) but also for cardiovascular disease (CVD). In this review article, we summarize the current evidence of CKD as a high-risk condition for CVD based on reports from Japan and other countries to draw attention...

journal_title：Journal of atherosclerosis and thrombosis

authors： Shoji T,Abe T,Matsuo H,Egusa G,Yamasaki Y,Kashihara N,Shirai K,Kashiwagi A,Committee of Renal and Peripheral Arteries, Japan Atherosclerosis Society.

更新日期：2012-01-01 00:00:00