Beta-blocker Treatment Does Not Worsen Critical Limb Ischemia in Patients Receiving Endovascular Therapy.

abstract：AIM:Withholding effective treatment is clinically prevalent. The CEntralized Pan-Asian survey on tHE Under-treatment of hypercholeSterolemia (CEPHEUS-PA) indicated suboptimal low-density lipoprotein cholesterol (LDL-C) goal attainment in Taiwan, which may be attributable to clinical inertia. We herein analyzed the Taiw...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wang KL,Wu CH,Wang KF,Chang CC,Chen LC,Lu TM,Lin SJ,Chiang CE

更新日期：2014-01-01 00:00:00

abstract：AIM:Epicardial adipose tissue (EAT) has been suggested as a contributing factor for coronary atherosclerosis based on the previous cross-sectional studies and pathophysiologic background. However, a causal relationship between EAT and the development of non-calcified coronary plaque (NCP) has not been investigated. ME...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hwang IC,Park HE,Choi SY

更新日期：2017-03-01 00:00:00

abstract：AIM:The Framingham risk score (FRS) is one of the standard tools used to predict the incidence of coronary heart disease (CHD). No previous study has investigated its efficacy for a Japanese population cohort. The purpose of this study was to develop new coronary prediction algorithms for the Japanese population in the...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nishimura K,Okamura T,Watanabe M,Nakai M,Takegami M,Higashiyama A,Kokubo Y,Okayama A,Miyamoto Y

更新日期：2014-01-01 00:00:00

abstract：AIM:A positive association between metabolic syndrome (MetS) and periodontal status has recently been noted. However, no study has evaluated the relationship by sex and in a general urban population using the uniform definition proposed in the 2009 Joint Interim Statement. The aim of this study was to clarify the relat...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kikui M,Kokubo Y,Ono T,Kida M,Kosaka T,Yamamoto M,Watanabe M,Maeda Y,Miyamoto Y

更新日期：2017-05-01 00:00:00

abstract：AIM:Lipoprotein lipase protein exists in preheparin serum (preheparin LpL mass), even though lipoprotein lipase activity is rarely detected. Recent clinical studies have clarified that low preheparin LpL mass concentration is an important coronary risk factor. The aim of this study was to clarify the effect of telmisar...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hitsumoto T,Takahashi M,Iizuka T,Shirai K

更新日期：2008-06-01 00:00:00

abstract：AIM:Although distal embolization during percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) deteriorates cardiac function, whether distal protection (DP) can improve prognosis is still controversial. We investigated whether a filter-type DP device, Filtrap®, could improve long-term outcomes a...

journal_title：Journal of atherosclerosis and thrombosis

authors： Teramoto R,Sakata K,Miwa K,Matsubara T,Yasuda T,Inoue M,Okada H,Kanaya H,Kawashiri MA,Yamagishi M,Hayashi K

更新日期：2016-12-01 00:00:00

abstract：AIM:The INK4b-ARF-INK4a locus in the chromosome 9p21 region is known to play an important role in the development of atherosclerosis. The INK4/ARF transcript p16(INK4a) inhibits the activity of the cyclin-dependent kinases CDK4/CDK6 and arrests cell-cycle progression. CDK inhibitors also regulate G1/S phase progression...

journal_title：Journal of atherosclerosis and thrombosis

authors： Bayoglu B,Arslan C,Gode S,Kaya Dagistanli F,Arapi B,Burc Deser S,Dirican A,Cengiz M

更新日期：2014-01-01 00:00:00

abstract：AIM:Cardiovascular events associated with hypertension often involve thrombosis. Increased platelet activity is one of the risk factors of cardiovascular diseases. Antithrombotic properties of antihypertensive agents are not fully characterized. Angiotensin II type 1 receptor blockers (ARBs) are widely used for the tre...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sato Y,Fujii S,Imagawa S,Ohmura K,Ohmura Y,Andoh Y,Dong J,Ishimori N,Furumoto T,Tsutsui H

更新日期：2007-02-01 00:00:00

abstract：AIM:Both vascular function and structure are independent predictors of cardiovascular events. The purpose of this study was to evaluate vascular function and structure of a leg artery in patients with peripheral artery disease (PAD). METHODS:We measured flow-mediated vasodilatation (FMD) and nitroglycerine-induced vas...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iwamoto A,Kajikawa M,Maruhashi T,Iwamoto Y,Oda N,Kishimoto S,Matsui S,Kihara Y,Chayama K,Goto C,Noma K,Aibara Y,Nakashima A,Higashi Y

更新日期：2016-11-01 00:00:00

abstract：AIM:To assess the long-term effects of intracoronary stem cell (SC) infusion following acute myocardial infarction (AMI) on the local atherosclerotic process at the site of infusion after four years of follow-up. METHODS:We evaluated 18 post-AMI patients. Group 1 consisted of nine patients given an intracoronary injec...

journal_title：Journal of atherosclerosis and thrombosis

authors： Benedek I,Bucur O,Benedek T

更新日期：2014-01-01 00:00:00

abstract：AIM:Atherosclerosis (AS) characterized as a chronic inflammatory disease. Multiple immune cells and inflammatory cytokines, such as high mobility group protein (HMGB1), regulatory T (Treg) cells, T helper (Th17) cells, and inflammation-related cytokines, play a key role in its pathophysiology. A large number of studies...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ding JW,Zheng XX,Zhou T,Tong XH,Luo CY,Wang XA

更新日期：2016-06-01 00:00:00

abstract：AIM:Epicardial adipose tissue (EAT) may be associated with arrhythmogenesis. P-wave indices such as P-wave dispersion and P-wave variation indicated a slowed conduction velocity within the atria. This study investigated the effect of dapagliflozin on EAT volume and P-wave indices. METHODS:In the present ad hoc analysi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sato T,Aizawa Y,Yuasa S,Fujita S,Ikeda Y,Okabe M

更新日期：2020-12-01 00:00:00

abstract：AIMS:Type 2 diabetes mellitus (T2DM) is no longer regarded as a coronary risk equivalent, and heterogeneity of cardiovascular risk exists, suggesting that further risk stratification should be mandatory. This study aimed to determine the prevalence and clinical predictors of coronary artery calcium (CAC) score, and eva...

journal_title：Journal of atherosclerosis and thrombosis

authors： Lei MH,Wu YL,Chung SL,Chen CC,Chen WC,Hsu YC

更新日期：2020-11-07 00:00:00

abstract：AIM:CCL22, mainly synthesized by monocyte-derived alternative (M2) macrophages, belongs to the CC family of chemokines and is involved in monocyte migration and recruitment. We have previously investigated CCL22 and histamine in atherosclerosis. Here, we investigated the hypothesis that CCL22 is involved in atheroscler...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kimura S,Noguchi H,Nanbu U,Wang KY,Sasaguri Y,Nakayama T

更新日期：2018-12-01 00:00:00

abstract：:Although many clinical studies have shown that a low testosterone level is associated with cardiovascular diseases, the role of androgens in cardiovascular physiology and pathophysiology remains controversial. Androgens exert various actions in their target organs, and the androgen receptor (AR) is widely distributed ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yoshida S,Ikeda Y,Aihara K

更新日期：2016-01-01 00:00:00

abstract：:To determine the recent serum lipid levels in the general Japanese population and trends in their changes over the past 30 years, a nationwide survey of serum lipid levels was conducted in 39 institutes from various districts around Japan. The total number of subjects were 34,815, consisting of 20,279 men and 14,536 w...

journal_title：Journal of atherosclerosis and thrombosis

authors：

更新日期：1996-01-01 00:00:00

abstract：AIMS:Perilipin and adipophilin, PAT family proteins, play important roles in lipid metabolism. Although nonalcoholic fatty liver disease (NAFLD) is initiated by hepatocyte lipidation, little is known about the relationship between these proteins and hepatocellular injury. We investigated the expressions of perilipin an...

journal_title：Journal of atherosclerosis and thrombosis

authors： Fujii H,Ikura Y,Arimoto J,Sugioka K,Iezzoni JC,Park SH,Naruko T,Itabe H,Kawada N,Caldwell SH,Ueda M

更新日期：2009-01-01 00:00:00

abstract：AIM:Up-regulation of soluble CD40 ligand (sCD40L) and of monocyte chemoattractant protein-1 (MCP-1) has been found in diabetes and in patients with acute cerebral ischemia. We asked whether (i) the two molecules are similarly upregulated among non-lacunar and lacunar diabetic strokes and (ii) sCD40L and/or MCP-1 predic...

journal_title：Journal of atherosclerosis and thrombosis

authors： Davì G,Tuttolomondo A,Santilli F,Basili S,Ferrante E,Di Raimondo D,Pinto A,Licata G

更新日期：2009-01-01 00:00:00

abstract：:Recent findings suggest that the oxidative modification of low-density lipoproteins (LDL) and an increase in triglyceride-rich lipoprotein particles including chylomicron remnants contribute to the progression of atherosclerosis, as does the inflammatory response. We therefore examined whether and how these lipoprotei...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okumura T,Fujioka Y,Morimoto S,Masai M,Sakoda T,Tsujino T,Kashiwamura S,Okamura H,Ohyanagi M

更新日期：2006-02-01 00:00:00

abstract：AIM:Clinical studies have suggested that renin-angiotensin inhibitors are effective for the prevention of atherosclerosis progression, but the results for the regression of established lesions are equivocal. The aim of this study was to examine the effects of different doses of the angiotensin receptor blocker (ARB) ca...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hayashi K,Sasamura H,Azegami T,Itoh H

更新日期：2012-01-01 00:00:00

abstract：AIM:The association between urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), an oxidative stress marker, and the incidence of cardiovascular disease (CVD) has not been confirmed because no previous studies evaluated 24-hour 8-OHdG excretion levels in the general population. We aimed to confirm the association between 24-h...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nagao M,Kobashi G,Umesawa M,Cui R,Yamagishi K,Imano H,Okada T,Kiyama M,Kitamura A,Sairenchi T,Haruyama Y,Ohira T,Iso H,CIRCS Investigators.

更新日期：2020-10-01 00:00:00

abstract：AIM:A novel device has been developed for measuring the cardio-ankle vascular index (CAVI) as an indicator of arterial stiffness. In this study, we evaluated the effect of pitavastatin on CAVI in type 2 diabetic patients. METHODS:Forty-five type 2 diabetes mellitus patients with low-density lipoprotein cholesterolemia...

journal_title：Journal of atherosclerosis and thrombosis

authors： Miyashita Y,Endo K,Saiki A,Ban N,Yamaguchi T,Kawana H,Nagayama D,Ohira M,Oyama T,Shirai K

更新日期：2009-10-01 00:00:00

abstract：:The aim was to give on overview of the profile of cardiovascular disease, vascular pathology and the relationships between lifestyle and cardiovascular disease in Japanese. Compared with the United States and Europe, the higher mortality from stroke and lower mortality from coronary heart disease constitute a unique c...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iso H

更新日期：2011-01-01 00:00:00

abstract：:The aim of this study was to observe the efficacy of atorvastatin and the related factors of meeting the National Cholesterol Education Program (NCEP)-recommended low-density lipoprotein (LDL) cholesterol levels in patients with hypercholesterolemia. A total of 107 patients were treated with atorvastatin 10 mg/day for...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yoshitomi Y,Tsujibayashi T,Ishii T,Sakurai S,Nagakura C,Miyauchi A,National Cholesterol Education Program.

更新日期：2003-01-01 00:00:00

abstract：AIM:To determine the effects of exercise training on total and high molecular weight (HMW) adiponectin and adiponectin oligomeric distribution. METHODS:A randomized parallel-design study (n=53; 40 women and 13 men; age range, 32?65 years) was conducted at a fitness club between April 2006 and July 2007. Participants w...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ando D,Hosaka Y,Suzuki K,Yamagata Z

更新日期：2009-01-01 00:00:00

abstract：:Blood lipid levels are highly heritable and modifiable risk factors for coronary artery disease (CAD), and are the leading cause of death worldwide. These facts have motivated human genetic association studies that have the substantial potential to define the risk factors that are causal and to identify pathways and t...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tada H,Kawashiri MA,Konno T,Yamagishi M,Hayashi K

更新日期：2016-01-01 00:00:00

abstract：:The purpose of the present study was to investigate the relationship between insulin resistance, sex hormones and sex hormone-binding globulin (SHBG) in regard to the serum lipid and lipoprotein profiles of 82 Japanese postmenopausal women. A multiple regression analysis for lipids, lipoproteins, and apoproteins as de...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kumagai S,Kai Y,Sasaki H

更新日期：2001-01-01 00:00:00

abstract：AIM:We investigated the effects of a calorie-restricted low-carbohydrate diet on glucose and lipid metabolism, and body fat distribution, especially on the secretion of leptin and lipoprotein lipase from adipose tissue in Otsuka Long Evans Tokushima Fatty (OLETF) rats. METHODS:Forty-three week-old male OLETF rats were...

journal_title：Journal of atherosclerosis and thrombosis

authors： Koide N,Oyama T,Miyashita Y,Shirai K

更新日期：2007-10-01 00:00:00

abstract：AIM:Was to evaluate the role of seven matrix metalloproteinase (MMP) polymorphisms in the genetic susceptibility to develop myocardial infarction in Mexican individuals. METHODS:Seven polymorphisms in the MMP genes were genotyped by 5' exonuclease TaqMan genotyping assays in 300 patients with myocardial infarction and...

journal_title：Journal of atherosclerosis and thrombosis

authors： Pérez-Hernández N,Vargas-Alarcón G,Martínez-Rodríguez N,Martínez-Ríos MA,Peña-Duque MA,Peña-Díaz Ade L,Valente-Acosta B,Posadas-Romero C,Medina A,Rodríguez-Pérez JM

更新日期：2012-01-01 00:00:00

abstract：AIM:Carotid intima-media thickness (CIMT) measurements are used as a disease outcome in randomized controlled trials that assess the effects of lipid-modifying treatment. It is unclear whether common CIMT or mean maximum CIMT should be used as the primary outcome. We directly compared both measurements using aspects th...

journal_title：Journal of atherosclerosis and thrombosis

authors： Dogan S,Kastelein JJ,Grobbee DE,Bots ML

更新日期：2011-01-01 00:00:00