Abstract：
PURPOSE:To evaluate the use of a peripheral stromal support to facilitate and improve the outcomes of Descemet's membrane endothelial keratoplasty (DMEK). DESIGN:Prospective case series. PARTICIPANTS:Ten patients with Fuchs' endothelial dystrophy. INTERVENTION:Pneumatic dissection was used to detach the central part of the Descemet's membrane and endothelium from the deep stroma. Endothelial grafts including a peripheral stromal support were obtained by eccentric punching of donor tissue and used to perform DMEK surgery in 10 patients. MAIN OUTCOME MEASURES:Operative time, graft attachment rate, best spectacle-corrected visual acuity (BSCVA), endothelial cell loss, refraction, and complications. RESULTS:In all cases the surgical time was ≤ 1 hour. The postoperative course was uneventful in all but 2 cases, which required rebubbling owing to early graft detachment. Final attachment rate was 100%. The average follow-up was 8.4 months (range, 6-12). Postoperative BSCVA was ≥ 20/40 in all cases and no substantial change in refraction was recorded. Postoperative endothelial cell loss averaged 24.1% (range, 8%-34.9%). CONCLUSIONS:Stromal support facilitates surgery, reduces complications, and appears to maintain the favorable outcomes of DMEK.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Busin M,Patel AK,Scorcia V,Galan A,Ponzin Ddoi
10.1016/j.ophtha.2010.03.038subject
Has Abstractpub_date
2010-12-01 00:00:00pages
2273-7issue
12eissn
0161-6420issn
1549-4713pii
S0161-6420(10)00317-9journal_volume
117pub_type
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