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Comparison of photorefractive keratectomy with excimer laser in situ keratomileusis in correcting low myopia (from -2.00 to -5.50 diopters). A randomized study.

Abstract：

OBJECTIVE:To compare laser in situ keratomileusis (LASIK) with photorefractive keratectomy (PRK) in the correction of myopia from -2.00 to -5.50 diopters. DESIGN:Prospective, randomized, paired clinical trial. PARTICIPANTS:Fifty-two eyes of 26 myopic patients were enrolled in the study. INTERVENTION:Each patient received PRK on one eye (PRK eye) and LASIK on the other (LASIK eye); the procedure assigned to each eye, and the sequence of surgeries for each patient was randomized. MAIN OUTCOME MEASURES:Slit-lamp microscopy, manifest refraction, uncorrected and spectacle-corrected visual acuity, and videokeratography were done before operation, and 2 weeks, 6 weeks, 3 months, 6 months, and 12 months after operation. Patient satisfaction and preference were assessed by a subjective questionnaire. RESULTS:All LASIK eyes had fast, painless recovery. At 1 year, 24 patients (92.3%) were examined, the mean spherical equivalent refraction was -0.08 +/- 0.38 diopter in the PRK eyes and -0.14 +/- 0.31 diopter in the LASIK eyes, and the uncorrected visual acuity was 20/20 or better in 15 PRK eyes (62.5%) and 19 LASIK eyes (79.2%); no eye lost 2 or more Snellen lines of spectacle-corrected visual acuity. Both procedures were stable throughout the first year. One PRK eye developed dense subepithelial corneal haze. The strongest correlate to spectacle-corrected visual acuity after the two procedures was the coefficient of variation of corneal power over the pupil. Nineteen patients (79.2%) preferred the LASIK procedure because of the fast, painless recovery. CONCLUSIONS:In the current study, PRK and LASIK were found to be similarly effective, predictable, stable, and reasonably safe for the correction of myopia between -2.00 and -5.50 diopters. Laser in situ keratomileusis has the advantage of fast, painless recovery. Patients prefer LASIK.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

el Danasoury MA,el Maghraby A,Klyce SD,Mehrez K

doi

10.1016/S0161-6420(99)90084-2

subject

Has Abstract

pub_date

1999-02-01 00:00:00

pages

411-20; discussion 420-1

issue

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(99)90084-2

journal_volume

106

pub_type

临床试验,杂志文章,随机对照试验

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Comparison of photorefractive keratectomy with excimer laser in situ keratomileusis in correcting low myopia (from -2.00 to -5.50 diopters). A randomized study.