Abstract：
PURPOSE:To evaluate visual outcomes and astigmatism in patients who underwent penetrating keratoplasty (PK) with 2 different incision techniques. DESIGN:Retrospective comparison of a consecutive surgical series. PARTICIPANTS:Fifty-seven consecutive patients who underwent PK at the University of California, Irvine, academic referral practice. METHODS:A comparison of 49 eyes of 43 patients that underwent femtosecond laser zig-zag incision pattern PK versus 17 eyes of 14 patients that underwent conventional Barron suction trephination PK performed contemporaneously. All PKs were closed with an identical, 24-bite running nylon suture technique. MAIN OUTCOME MEASURES:Topographically determined astigmatism, best spectacle-corrected visual acuity (BSCVA), and recovery of full visual potential. RESULTS:The postoperative follow-up ranged from 1 to 12 months. There was a significant difference in average astigmatism between the groups at postoperative month 1 (P = 0.013) and 3 (P = 0.018). By month 3, the average astigmatism was 3 diopters (D) in the zig-zag group and 4.46 D in the conventional group. Of the patients with normal macular and optic nerve function (n(ZZ) = 32; n(con) = 14), a significant difference in BSCVA was seen at month 1 (P = 0.0003) and month 3 (P = 0.006) with 81% of the zig-zag group versus 45% of the conventional group achieving BSCVA of > or =20/40 by month 3 (P = 0.03). CONCLUSIONS:The femtosecond laser generated zig-zag-shaped incision results in a more rapid recovery of BSCVA and induces less astigmatism compared with conventional blade trephination PK. FINANCIAL DISCLOSURE(S):Proprietary commercial disclosure may be found after the references.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Farid M,Steinert RF,Gaster RN,Chamberlain W,Lin Adoi
10.1016/j.ophtha.2009.05.003subject
Has Abstractpub_date
2009-09-01 00:00:00pages
1638-43issue
9eissn
0161-6420issn
1549-4713pii
S0161-6420(09)00484-9journal_volume
116pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract：:Neuropathic pain is caused by a primary lesion or dysfunction of the nervous system and can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined disease. Patients with NCP are extremely challenging to manage, and evidence-based clinical recommendations for the management of patients...
journal_title：Ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.ophtha.2017.08.004
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:To study early direct effects of transpupillary thermotherapy (TTT) on choroidal neovascularization (CNV) and choroid. DESIGN:Retrospective, noncomparative interventional case series. PARTICIPANTS:Sixty-four eyes with subfoveal CNV. INTERVENTION:TTT was delivered using a diode laser at 810 nm through a con...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(02)01034-5
更新日期：2002-06-01 00:00:00
abstract：OBJECTIVE:To determine whether ocular cicatricial pemphigoid (OCP) may represent a distinct immunopathologic disease when it is pure ocular cicatricial pemphigoid (POCP) (e.g., only confined to the conjunctiva) or when it is associated with skin or extraocular mucous membrane lesions or both (OCP+). DESIGN:Prospective...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/S0161-6420(99)90076-3
更新日期：1999-02-01 00:00:00
abstract：PURPOSE:To characterize quantitatively the configuration of the anterior ocular segment with ultrasound biomicroscopy (UBM) in a population-based setting. DESIGN:Cross-sectional study. PARTICIPANTS:Ten percent of 4632 residents aged > or =40 years of Kumejima, an island off southwest Japan, were randomly selected. M...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2010.01.045
更新日期：2010-09-01 00:00:00
abstract：:One hundred sixty eyes of 92 patients with diffuse diabetic maculopathy with or without cystoid macular edema were enrolled in a prospective randomized clinical trial to determine the efficacy of "modified grid" argon (blue-green) laser photocoagulation. At the 12- and 24-month follow-ups, visual acuity significantly ...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0161-6420(86)33638-8
更新日期：1986-07-01 00:00:00
abstract：:A 56-year-old white man presented with bilateral inferior lid tumors with a rubbery consistency suggesting lymphoid lesions. An excisional biopsy specimen of the larger lesion in the left lower lid led to routine pathologic, immunologic, histochemical, and electron microscopic investigations. The tumor displayed a dif...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(80)35138-5
更新日期：1980-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy and safety of phototherapeutic keratectomy (PTK) for treatment of striae in LASIK flaps. DESIGN:Retrospective consecutive series. PARTICIPANTS:Forty-seven eyes of 44 patients with flap striae after LASIK with reduced best-corrected visual acuity (VA) or visual symptoms with at least...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2006.09.023
更新日期：2007-06-01 00:00:00
abstract：:Dr. William O. Coffee was an ophthalmologist who conducted an office and mail-order practice in the Midwest from the 1880s until 1927. His main stock in trade was a self-discovered absorption cure for a variety of ocular diseases, with particular emphasis on the medical cure of cataracts. Dr. Coffee's career was a che...
journal_title：Ophthalmology
pub_type： 传,历史文章,杂志文章
doi：10.1016/s0161-6420(89)32758-8
更新日期：1989-08-01 00:00:00
abstract：PURPOSE:To describe associations between reticular pseudodrusen, individual characteristics, and retinal function. DESIGN:Cohort study. PARTICIPANTS:We recruited 105 patients (age range, 52-93 years) who had advanced neovascular age-related macular degeneration (AMD) in only 1 eye from 3 clinical centers in Europe. ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2014.03.015
更新日期：2014-09-01 00:00:00
abstract：:Cystic intranasal masses were found in seven newborn infants with congenital dacryocystocele. The cysts were a direct extension of the nasolacrimal duct, located beneath the inferior turbinate. Nasal obstruction was present in three infants and was severe enough to cause respiratory distress in two neonates with bilat...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(91)32149-3
更新日期：1991-08-01 00:00:00
abstract：OBJECTIVE:To report the authors' clinical experience with submacular surgery for subfoveal membranes in children and to evaluate the histopathologic findings of membranes in children with various etiologies of choroidal neovascularization. DESIGN:Retrospective, noncomparative, interventional case series. PARTICIPANTS...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/S0161-6420(99)00510-2
更新日期：1999-05-01 00:00:00
abstract：PURPOSE:To establish the accurate surgical anatomy of endonasal dacryocystorhinostomy (DCR) based on the radiological analysis of underlying bony structures. DESIGN:Prospective noncomparative observational case series study. PARTICIPANTS:Fifty-nine patients with complete nasolacrimal stenosis underwent a computed tom...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2005.01.012
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVE:To determine the cost-effectiveness of cataract surgery worldwide and to compare it with the cost-effectiveness of comparable medical interventions. DESIGN:Meta-analysis. PARTICIPANTS:Approximately 12,000 eyes in the studies selected. METHODS:Articles were identified by searching the literature using the p...
journal_title：Ophthalmology
pub_type： 杂志文章,meta分析
doi：10.1016/j.ophtha.2006.12.013
更新日期：2007-09-01 00:00:00
abstract：PURPOSE:The expression of cellular adhesion molecules in 31 penetrating keratoplasty specimens from a broad range of corneal inflammatory diseases was studied using monoclonal antibodies and an immunoperoxidase technique. METHODS:Corneas were divided into noninflamed, mild to moderately inflamed, and severely inflamed...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(94)31370-4
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:To evaluate the outcomes of changing immunosuppressive therapy for noninfectious uveitis after failure. DESIGN:Retrospective cohort study. PARTICIPANTS:Patients with noninfectious uveitis managed at 2 tertiary uveitis clinics in the United Kingdom and Australia. METHODS:Participants with a history of using i...
journal_title：Ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ophtha.2013.11.032
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:To document the long-term experience with hydroxyapatite (HA) orbital implants (Bio-Eye) and analyze the factors influencing implant exposure, including surgical type, procedural modification, use of different wrapping materials and peg materials. DESIGN:Retrospective observational case series. PARTICIPANTS...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2007.06.014
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVE:We have used an artificial neural network in an attempt to classify and predict the progression of thyroid-associated ophthalmopathy (TAO) at the first clinical examination. DESIGN:This retrospective comparative case series included a group of patients examined by the ophthalmologist only once because of the...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(02)01127-2
更新日期：2002-09-01 00:00:00
abstract：:From 1984 to 1989, 24 patients with desperate ocular surface wetting problems due to mucus deficiency syndrome with extensive symblephara or lid fusion were treated by autologous free transplants of nasal mucosa from the nasal conchae. This procedure covers the ocular surface not only with nonkeratinizing epithelium b...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(90)32471-5
更新日期：1990-08-01 00:00:00
abstract：PURPOSE:To determine whether differences between eyes in axial length (AL) and corneal power (K) on optical biometry are predictive of refractive outcomes. DESIGN:Retrospective cohort study. PARTICIPANTS:A total of 729 patients (1458 eyes) who underwent bilateral phacoemulsification at TLC (Mississauga, Ontario, Cana...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2018.01.021
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVES:To assess the clinical value of retinal or choroidal biopsy in establishing a definitive diagnosis directing subsequent management and to assess the risk involved in such surgery. DESIGN:Retrospective noncomparative interventional case series. PARTICIPANTS:Thirteen patients with uveitis of suspected malign...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2002.10.002
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND:Dislocation of nuclear lens fragments during phacoemulsification can lead to a high incidence of glaucoma, uveitis, and poor visual acuity. The correct approach to these patients is uncertain. The authors report on eight patients who underwent pars plana vitrectomy with removal of lens fragments. METHODS:Ch...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(92)31805-6
更新日期：1992-08-01 00:00:00
abstract：:Taping the superior aspect of patient masks qualitatively decreases air flow and bacterial dispersion towards the ocular surface while inappropriately worn masks both qualitatively and quantitatively increase bacterial dispersion towards the ocular surface. ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2021.01.007
更新日期：2021-01-11 00:00:00
abstract：PURPOSE:To describe the clinical and cytopathologic characteristics in patients with vitreous opacity of unknown cause or preceding inflammation, diagnosed cytopathologically as inflammation. DESIGN:Retrospective case series. PARTICIPANTS:Forty-three consecutive patients (61 eyes) who underwent vitrectomy for vitreou...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2011.10.020
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVE:To describe the long-term ophthalmologic outcomes of patients with methylmalonic aciduria and homocystinuria, cobalamin C type (cblC). DESIGN:Retrospective case series. PARTICIPANTS:All patients with cblC referred to the Department of Ophthalmology of the Centre Hospitalier Universitaire Sainte-Justine from...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2013.08.034
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Malignant glaucoma (ciliary block glaucoma; aqueous misdirection glaucoma) is an incompletely understood, rare and serious complication of intraocular surgery. METHODS:A woman with pseudophakic malignant glaucoma underwent successful neodymium: YAG (Nd:YAG) laser photodisruption of the anterior hyaloid face...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(93)31479-x
更新日期：1993-09-01 00:00:00
abstract：:This report details the presentation, workup, and treatment of the largest lacrimal duct cyst ever reported in the ophthalmic literature. Included in this report is the first computed tomographic (CT) image of this unusual lesion. Typical and atypical clinical features of this lacrimal sac cyst are emphasized. ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(87)33391-3
更新日期：1987-06-01 00:00:00
abstract：OBJECTIVE:To determine the most appropriate method for measuring the effect on contrast sensitivity of neodymium:YAG (Nd:YAG) posterior capsulotomy for early posterior capsular opacification (PCO). DESIGN:Prospective comparison of five different methods for luminous contrast sensitivity testing in patients undergoing ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/S0161-6420(99)90154-9
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVE:To analyze the association between retinoblastoma (Rb) and sebaceous carcinoma (SC) of the eyelid to improve surveillance of survivors of RB: DESIGN:Case report and systematic literature review. METHODS:Ten patients who had SC develop after Rb were identified by systematic literature review, and a child who...
journal_title：Ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0161-6420(01)00555-3
更新日期：2001-06-01 00:00:00
abstract：:The blue field entoptic technique was used to study autoregulation of the macular retinal circulation in response to acute alterations of intraocular pressure in 71 diabetic eyes and 30 normals matched for age, systemic blood pressure, and ophthalmic artery diastolic pressure. IOPmax, the maximal intraocular pressure ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(82)34720-x
更新日期：1982-07-01 00:00:00
abstract：PURPOSE:Several retrospective studies have demonstrated the safety and efficacy of sub-Tenon's anesthesia in ocular surgery. This is the first prospective randomized study comparing sub-Tenon's versus retrobulbar anesthesia for glaucoma surgery. METHODS:Thirty-nine patients undergoing both inpatient and day surgery tr...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0161-6420(93)31440-5
更新日期：1993-10-01 00:00:00
