Abstract：
:The blue field entoptic technique was used to study autoregulation of the macular retinal circulation in response to acute alterations of intraocular pressure in 71 diabetic eyes and 30 normals matched for age, systemic blood pressure, and ophthalmic artery diastolic pressure. IOPmax, the maximal intraocular pressure at which flow is maintained normal by autoregulation, was normal in eyes with no retinopathy (30 +/- 3.2 mm Hg) but decreased with progression of retinopathy, approaching the resting intraocular pressure in eyes with proliferative retinopathy. The hyperemia observed by normals to an acute reduction of intraocular pressure was not observed frequently in the diabetics with no retinopathy. The frequency of observation of the hyperemia decreased with progression of retinopathy and was uniformly absent in eyes with proliferative retinopathy. A group of eyes with minimal microangiopathy was found to have an abnormal IOPmax and no hyperemic response. The prognostic significance of these parameters remains to be established.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Sinclair SH,Grunwald JE,Riva CE,Braunstein SN,Nichols CW,Schwartz SSdoi
10.1016/s0161-6420(82)34720-xsubject
Has Abstractpub_date
1982-07-01 00:00:00pages
748-50issue
7eissn
0161-6420issn
1549-4713pii
S0161-6420(82)34720-Xjournal_volume
89pub_type
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