Abstract：
OBJECTIVE:To study early direct effects of transpupillary thermotherapy (TTT) on choroidal neovascularization (CNV) and choroid. DESIGN:Retrospective, noncomparative interventional case series. PARTICIPANTS:Sixty-four eyes with subfoveal CNV. INTERVENTION:TTT was delivered using a diode laser at 810 nm through a contact lens. Exposure time was 60 seconds with a power/diameter ratio of 247 mW/mm. The end point was an invisible treatment with no color change at the retina level. MAIN OUTCOME MEASURES:Fluorescein and indocyanine green angiographic findings within 1 hour, and at 1, 2, and 4 weeks after TTT. RESULTS:Fluorescein angiography (FA) and indocyanine green angiography (ICGA) performed within 1 hour after TTT showed increased leakage of CNV and choroidal vessels. Follow-up at 1 and 2 weeks demonstrated a hypofluorescent area corresponding to the laser spot and absence of angiographic leakage seen on FA and ICGA. At 4 weeks after TTT, FA showed mottled hypofluorescence-hyperfluorescence of the TTT-treated area and absence of angiographic leakage. CONCLUSIONS:TTT induces a characteristic dynamic sequence of vascular changes. Treatment with TTT can lead to absence of angiographic (FA and ICGA) leakage for 4 weeks. Determination of the long-term efficacy and visual implications awaits the results of clinical trials.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Lanzetta P,Michieletto P,Pirracchio A,Bandello Fdoi
10.1016/s0161-6420(02)01034-5subject
Has Abstractpub_date
2002-06-01 00:00:00pages
1098-104issue
6eissn
0161-6420issn
1549-4713pii
S0161-6420(02)01034-5journal_volume
109pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract：OBJECTIVE:To develop a simulator for training in phacoemulsification to be used as a learning device for both beginners and experienced surgeons to shorten the learning curve. DESIGN:Experimental study. METHODS:The system consists of a personal computer, a 3-dimensional visual interface, a phacoemulsification handpie...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2003.06.023
更新日期：2004-04-01 00:00:00
abstract：PURPOSE:To determine if patients with prior glaucoma surgery experience higher rates of postoperative graft dislocation after Descemet's stripping automated endothelial keratoplasty (DSAEK) and to determine if postoperative hypotony may be a risk factor in these patients. DESIGN:Retrospective, comparative analysis of ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2012.01.012
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:To identify any mutation of the UbiA prenyltransferase domain-containing protein 1 (UBIAD1) gene in Japanese patients with Schnyder's crystalline corneal dystrophy (SCCD) and to investigate in vivo microstructural phenotype and genotype correlations using laser scanning confocal microscopy (Heidelberg Retina ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2008.12.042
更新日期：2009-06-01 00:00:00
abstract：PURPOSE:To compare postoperative performance and stability of 6.0-mm optic single- and 3-piece acrylic foldable intraocular lenses (IOLs). DESIGN:Prospective, randomized, self-controlled trial. PARTICIPANTS:Eighty eyes of 40 patients with bilateral senile cataracts. INTERVENTION:Phacoemulsification and IOL implantat...
journal_title：Ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ophtha.2005.10.064
更新日期：2006-04-01 00:00:00
abstract：:The authors have reviewed the clinical presentation, visual fields, color vision testing, visual-evoked potentials, and computed tomographic (CT) findings of 58 patients (95 eyes) with dysthyroid optic neuropathy. The authors compared these findings to a control group of 60 patients (119 eyes) with thyroid eye disease...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(88)32978-7
更新日期：1988-11-01 00:00:00
abstract：:The successful management of suppurative microbial keratitis requires five steps: (1) make the clinical diagnosis, (2) perform the proper laboratory procedures, (3) initiate antimicrobial therapy, (4) modify the initial therapy, and (5) terminate therapy. The most helpful guidelines to decision-making in these steps a...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(81)34943-4
更新日期：1981-08-01 00:00:00
abstract：PURPOSE:This study was performed to determine the long-term efficacy, safety, and stability of noncontact holmium:yttrium aluminum garnet (Ho:YAG) laser thermal keratoplasty (LTK) for correction of low-to-moderate hyperopia. METHODS:The authors treated 1 eye each of 28 patients for correction of low-to-moderate hypero...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/s0161-6420(97)30003-7
更新日期：1997-11-01 00:00:00
abstract：:Fifty-eight patients with keratitis sicca were enrolled in a long-term study to test the effectiveness of slow-release artificial tears (SRAT). The average follow up period of 39 weeks, with a range of 9 to 136 weeks. Forty-six (79%) are still being followed. Almost all of these patients have had marked relief from th...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(81)35074-x
更新日期：1981-01-01 00:00:00
abstract：BACKGROUND:The authors treated ten patients (13 eyelids) with visually significant blepharoptosis and compromised corneal protective mechanisms resulting from paresis of ocular motility and absent Bell phenomenon. METHODS:Traditional upper eyelid surgery consisting of frontalis suspension (6 eyelids) or levator aponeu...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(97)30356-x
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:To evaluate the outcomes of combined deep sclerectomy and trabeculectomy (penetrating deep sclerectomy) in pediatric glaucoma. DESIGN:Retrospective, nonconsecutive, noncomparative, interventional case series. PARTICIPANTS:Children suffering from pediatric glaucoma who underwent surgery between March 1997 and ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2008.08.039
更新日期：2009-01-01 00:00:00
abstract：PURPOSE:The purpose of this article is to demonstrate how mobilization of the orbicularis oculi muscle can improve viability, appearance, and function of free skin grafts in the periocular region. By enhancing blood supply with this technique, healing often can be achieved in difficult reconstructive cases. METHODS:Se...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(95)30995-5
更新日期：1995-03-01 00:00:00
abstract：:The accurate clinical diagnosis of benign mixed tumors of the lacrimal gland is imperative for proper therapeutic management. Although benign mixed tumors of the orbital portion of the lacrimal gland have an established identity, those tumors arising in the palpebral lobe are unusual. Four patients with benign mixed t...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(90)32572-1
更新日期：1990-04-01 00:00:00
abstract：OBJECTIVE:To describe the safety and efficacy of an analgesia protocol that enables the surgeon to maintain control over an alert patient experiencing seemingly painless ambulatory cataract surgery, while eliminating the risks and side effects associated with general, local, topical, and intracameral anesthesia. DESIG...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(00)00008-7
更新日期：2000-05-01 00:00:00
abstract：:The effect of wearing schedule on extended-wear (EW) success was evaluated over a nine-month period by assigning 36 subjects to 5 different wearing schedules (removal every 4, 7, 14, or 28 days, or daily wear [DW]). All but one EW patient required interruption of extended wear at least once; half of the DW patients co...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(86)33768-0
更新日期：1986-02-01 00:00:00
abstract：PURPOSE:To compare 3-year outcomes and complications of the Ahmed FP7 Glaucoma Valve (AGV) (New World Medical, Cucamonga, CA) and the Baerveldt Glaucoma Implant (BGI) 101-350 (Abbott Medical Optics, Abbott Park, IL) for the treatment of refractory glaucoma. DESIGN:Multicenter, randomized, controlled clinical trial. P...
journal_title：Ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ophtha.2014.01.036
更新日期：2014-08-01 00:00:00
abstract：:One hundred twelve patients with vitiligo were examined for ocular abnormalities. Discrete areas of depigmentation with associated pigment hyperplasia clinically appearing to involve the choroid and retinal pigment epithelium were observed in 44 patients, and active uveitis was seen in nine patients. The changes obser...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(79)35413-6
更新日期：1979-06-01 00:00:00
abstract：:Forty-one of 97 eyes with retinal pigment epithelium decompensation (RPED) were treated with monochromatic green argon laser photocoagulation to the focal area of RPE staining detected in the late fluorescein transit. Nineteen eyes were treated because of progressive visual deterioration. The other 22 eyes already had...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(84)34118-5
更新日期：1984-12-01 00:00:00
abstract：PURPOSE:To evaluate the clinical features, treatment, and prognosis in patients with metastatic retinoblastoma. DESIGN:Retrospective interventional case series. PARTICIPANTS:Eighteen consecutive patients with metastatic retinoblastoma who were diagnosed and managed at the Oncology Service of Ankara University, Turkey...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2006.03.039
更新日期：2006-09-01 00:00:00
abstract：PURPOSE:To report the success rate of endoscopically assisted balloon dacryoplasty (EADCP) for treatment of acquired incomplete nasolacrimal duct obstructions (NLDOs). DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Records of patients treated for incomplete NLDOs with EADCP by one of the authors (WLW)...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2003.06.013
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVE:To determine the incidence and associations of glaucoma after pars plana vitrectomy (PPV) and silicone oil injection (SOI) for complicated retinal detachments and the response to treatment. DESIGN:Retrospective noncomparative case series. PARTICIPANTS:A total of 150 eyes of 150 patients who had completed a ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/S0161-6420(99)90017-9
更新日期：1999-01-01 00:00:00
abstract：:We studied 30 patients with opacifications of the posterior capsule to determine if the potential acuity meter (PAM) could accurately predict final visual outcome after Nd:YAG discussion. The final visual acuity was within one line of the PAM prediction in 22 of 30 patients (73%), better by two or more lines in seven ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(86)33723-0
更新日期：1986-03-01 00:00:00
abstract：PURPOSE:The authors examined the influences of diabetes on the results of visual function testing in patients with ocular hypertension (OHT). METHODS:Color vision (desaturated D-15), contrast sensitivity together with both transient and steady-state pattern electroretinogram (PERG) findings from patients with document...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(96)30489-2
更新日期：1996-09-01 00:00:00
abstract：PURPOSE:To evaluate changes in posterior corneal curvature as a possible cause of the hyperopic refractive shift observed after Descemet's stripping automated endothelial keratoplasty (DSAEK). DESIGN:Prospective, noncomparative, interventional case series. PARTICIPANTS:Thirty-four eyes of 29 patients with Fuchs' endo...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2009.04.035
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:To present the largest cohort of preschool children screened by the MTI PhotoScreener over a 9-year period from a single, statewide vision screening effort. DESIGN:Cross-sectional study. PARTICIPANTS:We included 147,809 children screened between May 1, 2000, and April 30, 2009 by a photoscreening program. ME...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2010.03.036
更新日期：2010-10-01 00:00:00
abstract：:A cross-sectional study was undertaken to determine the prevalence of ocular and oculodermal melanocytosis. Thirteen thousand one hundred fifty patients were examined for ocular and oculodermal melanocytosis. Fifty-three percent of these patients were black, 40% were white, and 7% were of other racial groups. In the w...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：
更新日期：1982-08-01 00:00:00
abstract：PURPOSE:The ability to detect reticular pseudodrusen (RPD)/subretinal drusenoid deposits (SDDs) using 12×12-mm widefield en face swept-source optical coherence tomography (SS-OCT) imaging was compared with conventional multimodal imaging (color, fundus autofluorescence (FAF), and infrared reflectance [IR] imaging) in e...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2016.10.009
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:To quantify the vitreous traction created by pneumatic (20-, 23-, and 25-gauge) and electric cutters (20- and 25-gauge) during vitrectomy. DESIGN:Experimental study. PARTICIPANTS:This is a preclinical study, and no patients were involved. METHODS:Five separate cutters for each drive mechanism and gauge (20-,...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2009.11.004
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVES:To determine the proportion of all Myocilin coding mutations responsible for advanced primary open-angle glaucoma (POAG) in early-age-at-onset individuals and to investigate the prevalence of exon 3 Myocilin mutations in advanced POAG at any age at onset in a large Australasian cohort. DESIGN:Cross-sectiona...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2012.11.029
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:To describe the clinical characteristics of and risk factors for the development of optic neuropathy after pars plana vitrectomy (PPV) for macula-sparing primary rhegmatogenous retinal detachment (RRD) repair. DESIGN:Retrospective case-control study. PARTICIPANTS:Seven patients who underwent PPV for macula-sp...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2012.06.002
更新日期：2012-11-01 00:00:00
abstract：OBJECTIVE:This study aimed to assess the effect of contact lens wear on the mucosal defenses of the outer eye against infection. DESIGN:A case-controlled study of daily contact lens wearers in their initial 6 months of contact lens wear. PARTICIPANTS:Contact lens wearers (mean age, 23.1 years; 47 subjects) were compa...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/S0161-6420(98)98031-9
更新日期：1998-08-01 00:00:00
