Abstract：
PURPOSE:The authors examined the influences of diabetes on the results of visual function testing in patients with ocular hypertension (OHT). METHODS:Color vision (desaturated D-15), contrast sensitivity together with both transient and steady-state pattern electroretinogram (PERG) findings from patients with documented OHT were examined in a historic cohort study. All patients were examined at least four times (mean, 7.8 examinations) during a follow-up period that ranged from 1.5 to 4 years. Only individuals who maintained normal visual fields throughout the follow-up period were included in this analysis. The sample included 158 patients with OHT. Of these patients, 32 were African-American and 23 had a history of noninsulin-dependent diabetes with no evidence of retinopathy (by ophthalmoscopy). Normative data were obtained from a control group that included 65 white subjects with normal vision who did not have diabetes and who were similar in age to the patients in the OHT group. RESULTS:Color vision, contrast sensitivity, and PERG results were reduced significantly in patients with diabetes and OHT relative to control subjects. Patients with OHT who did not have diabetes did not have similar abnormalities. Color vision and PERG results also were reduced significantly in patients with diabetes and OHT relative to those with OHT who did not have diabetes. Only the steady-state PERG was reduced in African-American patients with OHT (relative to both control subjects and white patients with OHT). CONCLUSIONS:Patients with diabetes and OHT have significantly greater color vision, contrast sensitivity and PERG abnormalities than patients with OHT without diabetes. Race factors do not play a major role in these differences. Screening for diabetes is recommended before drawing conclusions from the results of these types of functional tests in patients with OHT.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Vesti E,Trick GLdoi
10.1016/s0161-6420(96)30489-2subject
Has Abstractpub_date
1996-09-01 00:00:00pages
1419-25issue
9eissn
0161-6420issn
1549-4713pii
S0161-6420(96)30489-2journal_volume
103pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract：PURPOSE:To compare the rotational stability of the 2 most commonly used toric intraocular lenses (TIOLs). DESIGN:Retrospective cohort study in a single private practice. SUBJECTS:The study included all patients receiving an Acrysof (n = 626) or Tecnis TIOL (n = 647) over an 18-month period from April 2015 to Septembe...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2018.02.012
更新日期：2018-09-01 00:00:00
abstract：:A case of preseptal cellulitis caused by Mycobacterium intracellulare is presented. A 56-year-old white woman developed erythema, induration, and tenderness of the lids of her right eye after chalazion removal, which did not respond to three weeks of broad spectrum antibiotics. Incision and drainage with biopsy reveal...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(82)34762-4
更新日期：1982-05-01 00:00:00
abstract：PURPOSE:To compare monthly dosing with a treat and extend algorithm using ranibizumab 0.3 mg with and without angiography-guided macular laser photocoagulation for center-involving diabetic macular edema (DME). DESIGN:Multicenter, prospective, randomized clinical trial. PARTICIPANTS:A total of 150 eyes from 116 subje...
journal_title：Ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ophtha.2016.09.021
更新日期：2017-01-01 00:00:00
abstract：:The first 290 consecutive eyes (192 patients) to undergo radial keratotomy by one surgeon were evaluated prospectively. All had had complete preoperative evaluation and 269 (93%) were examined one or more years after surgery. Preoperatively, all patients except one had worse than 20/100 uncorrected visual acuity, 65% ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(84)34264-6
更新日期：1984-05-01 00:00:00
abstract：PURPOSE:To describe a patient with conjunctival metastasis as the initial manifestation of metastasis from a cutaneous melanoma. DESIGN:Single interventional case report. METHODS:A 48-year-old woman with a history of cutaneous axillary melanoma developed a rapidly growing conjunctival mass. Subsequent systemic evalua...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2004.04.020
更新日期：2004-10-01 00:00:00
abstract：PURPOSE:To investigate characteristics associated with visual and anatomic outcomes in branch and central retinal vein occlusion (BRVO and CRVO) patients treated with ranibizumab. DESIGN:Post hoc analysis of patients with BRVO and CRVO from 2 multicenter clinical trials who completed month 12 of the HORIZON extension ...
journal_title：Ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ophtha.2019.07.018
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:A trabeculectomy is frequently combined with extracapsular cataract surgery to minimize the risks of further optic nerve damage associated with intraocular pressure (IOP) elevations after cataract surgery in eyes with glaucoma. Acute IOP elevations still occur after this combined surgery. The author evaluated t...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0161-6420(93)31603-9
更新日期：1993-05-01 00:00:00
abstract：PURPOSE:The purpose of this article is to demonstrate how mobilization of the orbicularis oculi muscle can improve viability, appearance, and function of free skin grafts in the periocular region. By enhancing blood supply with this technique, healing often can be achieved in difficult reconstructive cases. METHODS:Se...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(95)30995-5
更新日期：1995-03-01 00:00:00
abstract：PURPOSE:To determine the independent, relative, and combined impact of reduced distance and near vision on the vision-specific quality of life (VS QOL) of adults in Timor-Leste. DESIGN:A population-based cross-sectional eye health survey was conducted in urban and rural areas in Timor-Leste. PARTICIPANTS:Participants...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2010.03.041
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:To characterize the types and frequencies of image artifacts associated with macular scanning using 2 common spectral-domain optical coherence tomography (SD OCT) instruments and to evaluate the impact of artifacts on foveal thickness measurements. DESIGN:Retrospective, observational chart review. PARTICIPANT...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2009.10.029
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVE:To test whether alternate day vitamin E affects the incidence of age-related macular degeneration (AMD) in a large-scale randomized trial of women. DESIGN:Randomized, double-masked, placebo-controlled trial. PARTICIPANTS:Thirty-nine thousand eight hundred seventy-six apparently healthy female health profess...
journal_title：Ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ophtha.2009.10.043
更新日期：2010-06-01 00:00:00
abstract：:A study group of eight patients with diabetic retinopathy and marked accumulation of hard exudates in the fundi is described. There was a significant increase in serum triglyceride levels (P less than 0.05) in the study group as compared to a control group of 23 consecutive patients with diabetic retinopathy. This exu...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(84)34098-2
更新日期：1984-12-01 00:00:00
abstract：OBJECTIVE:To determine the outcome of pediatric dacryocystorhinostomy (DCR) for large mucoceles or for primary nasolacrimal duct obstruction unresponsive to multiple probings. DESIGN:Retrospective noncomparative case series. PARTICIPANTS:One hundred thirty-four external dacryocystorhinostomies were performed in 121 c...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(01)00699-6
更新日期：2001-09-01 00:00:00
abstract：:Twelve patients with hypereosinophilic syndrome were studied to determine the frequency and type of eye involvement in this systemic disease. Four patients (33%) had visual symptoms, including blurred vision in one or both eyes, and one patient had an episode of complete blindness following cardiac surgery. Five patie...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(82)34625-4
更新日期：1982-12-01 00:00:00
abstract：:Two patients, a 43-year-old woman and a 62-year-old man, developed benign peripheral nerve sheath tumors (neurofibromas) of the lacrimal gland, in the former case of the deep orbital lobe, and in the latter of the palpebral lobe. A neurogenic tumor was not seriously considered clinically in either case, because of the...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(83)34365-7
更新日期：1983-12-01 00:00:00
abstract：PURPOSE:To evaluate the safety, efficacy, and quality of vision after photorefractive keratectomy (PRK) in active-duty military personnel. METHODS:Photorefractive keratectomy (6.0-mm ablation zone) was performed on 30 navy/marine personnel(-2.00 to -5.50 diopters [D]; mean, -3.35 D). Glare disability was assessed with...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(96)30733-1
更新日期：1996-01-01 00:00:00
abstract：:Long-term management of cytomegalovirus (CMV) retinitis by intravitreal injection of ganciclovir was evaluated in ten patients with acquired immune deficiency syndrome (AIDS). Patients were unable to tolerate systemic ganciclovir because of severe neutropenia (8 cases), catheter-induced sepsis (1 case), or the need to...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(89)32900-9
更新日期：1989-03-01 00:00:00
abstract：PURPOSE:To investigate the ability of sectorial analysis using the Heidelberg Retinal Tomograph 3 (HRT3) to discriminate between healthy and glaucomatous eyes and to determine whether this is affected by disc size and glaucoma severity. DESIGN:Multicenter, cross-sectional evaluation of diagnostic tests. PARTICIPANTS:...
journal_title：Ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ophtha.2009.01.020
更新日期：2009-06-01 00:00:00
abstract：PURPOSE:The purpose of this study was to evaluate 24-hour intraocular pressure (IOP) control in patients with moderate to severe open-angle glaucoma treated by trabeculectomy and mitomycin C versus maximum tolerated medical therapy. DESIGN:Prospective observational study. PARTICIPANTS:Thirty surgical patients and 30 ...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/j.ophtha.2006.01.029
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a rare disorder. This study investigated the types of ocular signs and symptoms in patients with POEMS and any systemic factors that may be associated with development of such ocular findings. DESIGN:Cas...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2010.08.013
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:To determine the efficacy of a combination of 5-fluorouracil and low-molecular-weight heparin (LMWH) to improve the outcome of surgery for established proliferative vitreoretinopathy (PVR). DESIGN:Double-masked, prospective, randomized, placebo-controlled clinical trial. SETTING:Three tertiary-referral teac...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ophtha.2004.05.036
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVE:The aims of this study were to describe the clinical features and biometric findings in the eyes of children with coloboma and to develop a classification of coloboma that correlates with visual function. DESIGN:Retrospective observational case series. PARTICIPANTS:One hundred thirteen children and young ad...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(99)00140-2
更新日期：2000-03-01 00:00:00
abstract：PURPOSE:Novel anterior segment optical coherence tomography (ASOCT) parameters associated with angle closure include anterior chamber area (ACA), anterior chamber volume (ACV), anterior chamber width (ACW), lens vault (LV), iris thickness (IT), iris area (I-area), and iris curvature (I-curv). We aimed to investigate ch...
journal_title：Ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ophtha.2012.01.019
更新日期：2012-07-01 00:00:00
abstract：:The recent establishment of a rare book collection as part of the American Academy of Ophthalmology Foundation Museum gives Academy members additional access to an important facet of our ophthalmic heritage. Many 17th and 18th century works, such as those of Cotton Mather and Philip Syng Physick, long remained in manu...
journal_title：Ophthalmology
pub_type： 历史文章,杂志文章
doi：10.1016/s0161-6420(86)33693-5
更新日期：1986-05-01 00:00:00
abstract：OBJECTIVE:A study was conducted to determine the sensitivity and specificity of masked experts in classifying results obtained from normal eyes, glaucomatous eyes, and eyes suspicious for glaucoma using the Nerve Fiber Analyzer GDx (Laser Diagnostic Technologies, San Diego, CA), a scanning polarimeter. DESIGN:Retrospe...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(00)00652-7
更新日期：2001-05-01 00:00:00
abstract：PURPOSE:To estimate retinal ganglion cell (RGC) losses associated with the earliest development of visual field defects in glaucoma. DESIGN:Observational cohort study. PARTICIPANTS:The study group included 53 eyes of 53 patients with suspected glaucoma who were followed as part of the Diagnostic Innovations in Glauco...
journal_title：Ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ophtha.2012.09.039
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND:Non-Hodgkin lymphoma is more common in patients with the acquired immune deficiency syndrome (AIDS), and the incidence of non-Hodgkin lymphoma in the AIDS population has been increasing as the life expectancy of these patients has increased. Nevertheless, intraocular lymphoma, as part of primary central nerv...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(94)31248-6
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of nerve growth factor (NGF) in patients with neurotrophic keratitis. DESIGN:Prospective, noncomparative, interventional case series. PARTICIPANTS:Forty-five eyes of 43 consecutive patients with moderate (stage 2, n = 17) to severe (stage 3, n = 28) neurotrophic keratitis unresponsi...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/s0161-6420(00)00163-9
更新日期：2000-07-01 00:00:00
abstract：PURPOSE:The purpose of the study is to evaluate the induced astigmatism after spherical photorefractive keratectomy on the Summit Omnimed (Summit Instruments, Waltham, MA) and the Nidek EC-5000 (Nidek Co. Ltd, Aichi, Japan) excimer lasers. METHODS:A total of 4269 eyes of 3289 patients were treated with a 5-mm optical ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(97)30141-9
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVE:The authors describe the clinical findings and surgical treatment of two patients affected by chronic eyelid lymphedema associated with facial acne rosacea. DESIGN:Two interventional case reports. METHODS AND INTERVENTION: The clinical diagnosis of acne rosacea was based on the physical examination and confi...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(00)00429-2
更新日期：2000-12-01 00:00:00
