Abstract:
PURPOSE:To determine if patients with prior glaucoma surgery experience higher rates of postoperative graft dislocation after Descemet's stripping automated endothelial keratoplasty (DSAEK) and to determine if postoperative hypotony may be a risk factor in these patients. DESIGN:Retrospective, comparative analysis of an interventional case series. PARTICIPANTS:Eight hundred fifty-four eyes (67 eyes with prior glaucoma surgery and 787 controls) from 582 patients who underwent DSAEK at 1 institution between January 2005 and April 2011. METHODS:Groups were compared with regard to preoperative, intraoperative, and postoperative parameters. Continuous variables were compared using the independent samples t test or Mann-Whitney U test. Categorical variables were compared using the chi-square test or Fisher exact test. MAIN OUTCOME MEASURES:Frequencies of postoperative graft dislocation and postoperative hypotony. RESULTS:Study eyes before surgery differed from control eyes with regard to corneal thickness (768 vs. 655 μm; P<0.001) and intraocular pressure (13 vs. 16 mmHg; P<0.001). Postoperative graft dislocation occurred significantly more frequently in study eyes compared with control eyes (9% vs. 2%; P = 0.008). Among eyes in which dislocation occurred, postoperative hypotony was present in 5 study eyes (83%) and 0 control eyes. CONCLUSIONS:Previous glaucoma surgery was associated with a significantly increased rate of graft dislocation compared with control eyes. Dislocation was related strongly to postoperative hypotony in eyes with prior glaucoma surgery. FINANCIAL DISCLOSURE(S):Proprietary or commercial disclosure may be found after the references.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Goshe JM,Terry MA,Li JY,Straiko MD,Davis-Boozer Ddoi
10.1016/j.ophtha.2012.01.012subject
Has Abstractpub_date
2012-06-01 00:00:00pages
1130-3issue
6eissn
0161-6420issn
1549-4713pii
S0161-6420(12)00032-2journal_volume
119pub_type
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