Abstract:
:Fifty-eight patients with keratitis sicca were enrolled in a long-term study to test the effectiveness of slow-release artificial tears (SRAT). The average follow up period of 39 weeks, with a range of 9 to 136 weeks. Forty-six (79%) are still being followed. Almost all of these patients have had marked relief from their symptoms and a significant decrease in corneal abnormalities. The high rate of success in this patient population was probably due in large part to patient selection, that is, patients were quite symptomatic and had been symptomatic for an average of three years prior to entering this study. For patients with fairly severe keratitis sicca for whom artificial tears alone are insufficient, SRAT offers an important and practical means of markedly decreasing symptoms and improving vision with ony minor side effects.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Werblin TP,Rheinstrom SD,Kaufman HEdoi
10.1016/s0161-6420(81)35074-xsubject
Has Abstractpub_date
1981-01-01 00:00:00pages
78-81issue
1eissn
0161-6420issn
1549-4713pii
S0161-6420(81)35074-Xjournal_volume
88pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract:PURPOSE:To investigate if previous intravitreal therapy is a predictor of posterior capsule rupture (PCR) during cataract surgery. DESIGN:Multicenter, national electronic medical record (EMR) database study with univariate and multivariate regression modeling. PARTICIPANTS:A total of 65 836 eyes of 44 635 patients un...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2016.02.014
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:To investigate whether confluent drusen may be accompanied by fluid accumulation underneath the sensory retina and to determine if the detection of subretinal fluid on spectral-domain optical coherence tomography (OCT) in patients with coalescent drusen is indicative of choroidal neovascularization (CNV). DESI...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.04.017
更新日期:2011-01-01 00:00:00
abstract::Carbonic anhydrase inhibitors used in the treatment of glaucoma are rarely associated with blood dyscrasias. Several case reports of aplastic anemia with use of acetazolamide, and two cases with use of methazolamide, have appeared in the literature. This report documents two cases of aplastic anemia, at least one of w...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(80)35229-9
更新日期:1980-04-01 00:00:00
abstract:PURPOSE:To evaluate photodynamic therapy (PDT) for symptomatic circumscribed choroidal hemangioma (CCH). DESIGN:Prospective, multicenter, nonrandomized clinical trial. PARTICIPANTS:Thirty-one eyes of 31 patients with posterior pole CCH and symptoms caused by exudation into the macular area. INTERVENTION:Photodynamic...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2008.08.029
更新日期:2009-01-01 00:00:00
abstract::A review of all cases of aponeurotic repair done since 1980 by the author identified 140 patients and 174 eyelids. An acceptable result at 6 weeks was defined as a lid level within 1 mm of the desired level achieved in 74% of lids with acquired ptosis. The amount of ptosis present preoperatively was the major factor i...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract:OBJECTIVE:This study aimed to review the best postoperative visual recovery in patients with macula-off detachments of 7 days' duration or less. DESIGN:Noncontrolled, prospective, interventional case series. PARTICIPANTS:A total of 104 patients with macula-off detachments of 7 days or less were studied, and the time ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(98)91142-3
更新日期:1998-11-01 00:00:00
abstract:PURPOSE:To determine the microstructure of the fovea in patients with Stickler syndrome using imaging by spectral-domain optical coherence tomography (SD OCT) and swept-source OCT. DESIGN:Retrospective case series study. PARTICIPANTS:A total of 39 eyes of 25 patients with genetically confirmed Stickler syndrome were ...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2017.01.046
更新日期:2017-06-01 00:00:00
abstract::Nabilone is a synthesized crystalline benzopyran that resembles the cannabinols but is not a tetrahydrocannabinol. Oral administration of 0.5 to 2 mg to patients with open-angle glaucoma reduced the intraocular pressure from 10% to 54% with an average of 28%. Administration of a topical ophthalmic nabilone solution (0...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(79)35539-7
更新日期:1979-01-01 00:00:00
abstract::Circadian rhythms in serotonin metabolism have been observed in the pineal gland and retina, and there is evidence that the levels of serotonin and melatonin in these tissues may mediate events in the brain's sleep-wake cycle and the retina's cycle of disc shedding. Because the ciliary epithelium, which produces aqueo...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(88)33025-3
更新日期:1988-09-01 00:00:00
abstract::The authors prospectively studied 106 consecutive phakic eyes with acute posterior vitreous detachment to determine the correlation between anterior vitreous pigment granules and retinal breaks. Pigment granules were identified in 15 eyes (14.1%), all of which had either a flap or an operculated retinal break. A retin...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32124-9
更新日期:1991-09-01 00:00:00
abstract:OBJECTIVE:To compare the long-term safety and ocular-hypotensive efficacy of brimonidine tartrate 0.2% with timolol maleate 0.5% administered twice daily in patients with glaucoma or ocular hypertension. DESIGN:A double-masked, parallel-group, active-controlled, multicenter clinical trial of 12 months' duration. PART...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0161-6420(98)91048-x
更新日期:1998-10-01 00:00:00
abstract:PURPOSE:To investigate when retinal pigment epithelium (RPE) tears occur and their associated treatment patterns and long-term visual outcomes in patients with neovascular age-related macular degeneration (nAMD) during anti-vascular endothelial growth factor (VEGF) treatment. DESIGN:Case-control analysis from a prospe...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2017.08.039
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To determine the association between physical activity levels and the rate of visual field (VF) loss in glaucoma. DESIGN:Longitudinal, observational study. PARTICIPANTS:Older adults with suspect or manifest glaucoma. METHODS:Participants wore accelerometers for 1 week to define average steps per day, minutes...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2018.10.012
更新日期:2019-07-01 00:00:00
abstract::Although the majority of aphakic patients will have intraocular lens implants (IOLs), there are several groups of patients for whom IOLs are not indicated. Synthetic keratophakia for the correction of aphakia has several inherent advantages over alternative forms of refractive surgery which use lathed corneal tissue. ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(87)33342-1
更新日期:1987-08-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine the prevalence of open-angle glaucoma and ocular hypertension in an Australian community whose residents are 49 years of age or older. SUBJECTS:There were 3654 persons, representing 82.4% of permanent residents from an area west of Sydney, Australia, who were examined...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(96)30449-1
更新日期:1996-10-01 00:00:00
abstract::Computed tomographic scanning is an excellent modality for evaluation of most orbital and intracranial tumors and strokes. However, MR scanning is definitely superior to CT when evaluating for multiple sclerosis, posterior fossa lesions (evaluation of gaze palsies, internuclear ophthalmoplegia, and downbeat nystagmus)...
journal_title:Ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/s0161-6420(89)32877-6
更新日期:1989-04-01 00:00:00
abstract:PURPOSE:Advances in cataract removal using topical anesthesia through a clear corneal microincision have created a new opportunity to fully correct refractive errors at the time of cataract surgery. This study was undertaken to assess the effectiveness of keratolenticuloplasty (KLP), the simultaneous modification of th...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(97)30304-2
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:Optic nerve gangliogliomas are extremely rate tumors of the central nervous system composed of elements of glial and neuronal origin. The clinical and biologic behavior of gangliogliomas depends on the glial component. Pilocytic gangliogliomas generally have a low growth rate and good ultimate prognosis. No ...
journal_title:Ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/s0161-6420(96)30613-1
更新日期:1996-05-01 00:00:00
abstract::Seven cases of hypofunctioning trabeculectomies or full-thickness filters were treated using the Q-switched neodymium:YAG (Nd:YAG) laser delivered either transconjunctivally, gonioscopically, or by a combination approach. In four eyes, internal laser revision was attempted initially. Internal revision was successful i...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32314-5
更新日期:1991-02-01 00:00:00
abstract:PURPOSE:To calculate the relationship between Medicare payment and service volume for the 3 highest-volume retina procedures: intravitreal injection (Current Procedural Terminology [CPT] code 67028), laser treatment for retinal edema (CPT code 67210), and laser treatment for proliferative retinopathy (CPT code 67228). ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2015.04.040
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:To assess agreement between rotating Scheimpflug camera and ultrasound pachymetry in measuring graft central thickness, and compare reproducibility/repeatability of these methods in corneal grafts and normal corneas. DESIGN:Experimental study. PARTICIPANTS:Sixty-five patients with corneal grafts after penetra...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2006.10.059
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and efficacy of transnasal orbital decompression for severe Graves' ophthalmopathy. DESIGN:Retrospective noncomparative case series with extended clinical follow-up. PARTICIPANTS:Seventy-eight consecutive subjects who were operated on for compressive optic neuropathy with loss of visu...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00533-9
更新日期:2001-02-01 00:00:00
abstract:PURPOSE:To investigate the associations of serum amyloid A (SAA) protein and soluble tumor necrosis factor receptors 1 and 2 (sTNF-R1 and sTNF-R2) with diabetic retinopathy (DR) in Hispanics. DESIGN:Prospective, nonrandomized, cross-sectional, family-based observational cohort study. PARTICIPANTS:A total of 473 Hispa...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.10.040
更新日期:2012-05-01 00:00:00
abstract::This paper presents a sampling of the psychophysical and electrophysiologic examinations which have been applied to determine the location of the visual processing defect in functional amblyopia. Areal summation and lateral inhibition are discussed along with methods for determining their extent at different locations...
journal_title:Ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/s0161-6420(78)35650-5
更新日期:1978-05-01 00:00:00
abstract:PURPOSE:To evaluate visual outcomes and astigmatism in patients who underwent penetrating keratoplasty (PK) with 2 different incision techniques. DESIGN:Retrospective comparison of a consecutive surgical series. PARTICIPANTS:Fifty-seven consecutive patients who underwent PK at the University of California, Irvine, ac...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.05.003
更新日期:2009-09-01 00:00:00
abstract::A 39-year-old man had an enlarging intrastromal iris cyst that obstructed the chamber angle inferotemporally and abutted the cornea. No history of ocular trauma or previous surgery was present. Iridocyclectomy with en bloc resection of the cyst was performed. The cyst was lined by one to three cell layers of focally p...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(85)34093-9
更新日期:1985-12-01 00:00:00
abstract:PURPOSE:To study the clinicopathologic features of mantle cell lymphoma (MCL) in the ocular adnexal region. DESIGN:Retrospective review. METHODS:The slides of 23 suspect patients were reevaluated with a panel of monoclonal antibodies, including anti-CD20, cyclin-D1, CD5, CD3, and p53 immunostains. Patients confirmed ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2004.07.025
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:We developed low-concentration homogenized castor oil eye drops for the treatment of patients with noninflamed obstructive meibomian gland dysfunction (MGD), a major cause of lipid-deficiency dry eye, and assessed the safety, stability, and efficacy of the eye drops. DESIGN:Randomized, double-masked, placebo...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0161-6420(02)01262-9
更新日期:2002-11-01 00:00:00
abstract:PURPOSE:To investigate the adherence of one clinically relevant ocular isolate of Staphylococcus epidermidis to polymethyl methacrylate (PMMA) and Acrysof (Alcon Surgical, Fort Worth, TX) intraocular lenses (IOLs). DESIGN:Experimental study. PARTICIPANTS:The authors examined the in vitro adherence of one clinically r...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00080-4
更新日期:2000-06-01 00:00:00
abstract:OBJECTIVE:The authors describe the clinical findings and surgical treatment of two patients affected by chronic eyelid lymphedema associated with facial acne rosacea. DESIGN:Two interventional case reports. METHODS AND INTERVENTION: The clinical diagnosis of acne rosacea was based on the physical examination and confi...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00429-2
更新日期:2000-12-01 00:00:00