Autologous nasal mucosa transplantation in severe bilateral conjunctival mucus deficiency syndrome.

Abstract:

:From 1984 to 1989, 24 patients with desperate ocular surface wetting problems due to mucus deficiency syndrome with extensive symblephara or lid fusion were treated by autologous free transplants of nasal mucosa from the nasal conchae. This procedure covers the ocular surface not only with nonkeratinizing epithelium but also with goblet cells and produces a mucus layer. This was proven by biopsy in three patients after 1 to 3 years. In all of the patients, conjunctival transplants were not available. Pronounced relief of pain and modest visual improvements are achieved with this procedure, and free autologous nasal mucosal grafts appear to be superior to buccal mucosa in reestablishing the anterior ocular surface. The authors recommend the technique for all patients with massive and otherwise intractable symblephara following lye burns.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Naumann GO,Lang GK,Rummelt V,Wigand ME

doi

10.1016/s0161-6420(90)32471-5

subject

Has Abstract

pub_date

1990-08-01 00:00:00

pages

1011-7

issue

8

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(90)32471-5

journal_volume

97

pub_type

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