Abstract：
OBJECTIVE:To determine the safety and efficacy of subconjunctival triamcinolone (Kenalog) in treating nonnecrotizing anterior scleritis. DESIGN:The authors conducted a retrospective review of all patients treated with depot subconjunctival corticosteroid injection for scleritis from January 1988 to May 1993. Response to therapy was determined by subjective improvement in pain and a decrease in clinical signs of ocular inflammation. All patients received subconjunctival injections of triamcinolone by the same technique, and the minimum observation period for complications was 6 weeks. RESULTS:Eighteen patients (90%) had relief of their symptoms with clinically observable improvement in inflammation, whereas two patients (10%) responded poorly. Nine patients (45%) required no further therapy. Average symptom-free interval was 18 weeks in patients with recurrent scleritis. No complications of scleral thinning, perforation, or glaucoma occurred in any patients. CONCLUSION:Subconjunctival triamcinolone injection is highly efficacious in treating nonnecrotizing anterior scleritis without unreasonable risk of thinning and/or perforation and should be considered as adjunctive therapy in localized disease.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Tu EY,Culbertson WW,Pflugfelder SC,Huang A,Chodosh JCdoi
10.1016/s0161-6420(95)30963-3subject
Has Abstractpub_date
1995-05-01 00:00:00pages
718-24issue
5eissn
0161-6420issn
1549-4713pii
S0161-6420(95)30963-3journal_volume
102pub_type
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