Surgical management of subfoveal neovascularization in children.

Abstract:

OBJECTIVE:To report the authors' clinical experience with submacular surgery for subfoveal membranes in children and to evaluate the histopathologic findings of membranes in children with various etiologies of choroidal neovascularization. DESIGN:Retrospective, noncomparative, interventional case series. PARTICIPANTS:Twelve eyes of 12 consecutive children with subfoveal choroidal neovascularization treated by vitrectomy and excision of the choroidal neovascular complex. INTERVENTION:Vitrectomy, excision of the choroidal neovascular complex, and air-fluid exchange. MAIN OUTCOME MEASURES:Visual acuity and recurrence of choroidal neovascular membrane. RESULTS:Preoperative visual acuities ranged from 20/60 to 20/800 (median, 20/300). Postoperative visual acuities ranged from 20/25 to 20/400 (median, 20/80) after an average follow-up of 20 months (range, 7-62 months). Ten of 12 eyes improved from immediate preoperative visual acuity, and four eyes developed recurrence of neovascular membranes over a mean follow-up of 18 months. Histopathologic examination of six excised membranes showed that the most common components of the membranes were retinal pigment epithelium, fibrocytes, vascular endothelium, and collagen. CONCLUSION:Selected eyes of children with subfoveal neovascular membranes and no evidence of membrane regression may benefit from submacular surgery. The histopathologic findings were similar to adult choroidal neovascularization not associated with age-related macular degeneration.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Sears J,Capone A Jr,Aaberg T Sr,Lewis H,Grossniklaus H,Sternberg P Jr,DeJuan E

doi

10.1016/S0161-6420(99)00510-2

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

920-4

issue

5

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(99)00510-2

journal_volume

106

pub_type

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